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Found 43 studies with search of: Open Studies | "Scleroderma, Systemic"
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Rank Status Study
1 Recruiting Effectiveness of UVA1-irradiation in the Treatment of Early Skin Fibrosis in Patients Suffering From Systemic Sclerosis
Conditions: Systemic Scleroderma;   Systemic Sclerosis
Interventions: Radiation: UVA1;   Other: UVA1
2 Recruiting Imatinib in Systemic Sclerosis
Condition: Scleroderma, Systemic
Intervention: Drug: Imatinib mesylate
3 Recruiting A Study to Evaluate the Safety and Efficacy of Abatacept in Patients With Diffuse Systemic Sclerosis (Scleroderma)
Conditions: Scleroderma, Diffuse;   Scleroderma, Systemic
Intervention: Drug: Abatacept
4 Recruiting A Study to Evaluate the Efficacy of an Oral Medication in the Treatment and Prevention of Digital Ulcers in Patients With Systemic Sclerosis (Scleroderma).
Conditions: n Ulcer;   Scleroderma, Systemic
Intervention: Drug: Ambrisentan
5 Recruiting AIMSPRO in Established Diffuse Cutaneous Systemic Sclerosis
Condition: Systemic Sclerosis
Interventions: Drug: Hyperimmune caprine serum;   Drug: Albumin
6 Recruiting Platelet Gel in Systemic Sclerosis
Condition: Scleroderma, Systemic
Intervention: Drug: Platelet Gel
7 Recruiting Pharmacokinetics of Oral Treprostinil in Patients With Systemic Sclerosis
Condition: Systemic Sclerosis
Intervention: Drug: treprostinil diethanolamine
8 Recruiting Genetic Study of the FBN1 Gene and Fibrillin-1 Abnormalities in Choctaw Native Americans and Other Patients With Systemic Sclerosis
Condition: Systemic Sclerosis
Intervention:
9 Recruiting A Study Using The Experimental Drug Called Imatinib (Gleevec) in Subjects With Systemic Sclerosis
Conditions: Alveolitis;   Systemic Sclerosis
Intervention: Drug: Gleevec
10 Recruiting Skin Biopsy Specimens as Biomarkers of Systemic Sclerosis and Response to Various Treatments
Condition: Systemic Sclerosis
Intervention:
11 Recruiting Exercise Induced Pulmonary Hypertension in Systemic Sclerosis and Treatment With Ambrisentan
Conditions: Systemic Sclerosis;   Shortness of Breath;   Pulmonary Hypertension
Intervention: Drug: Ambrisentan
12 Recruiting Pulmonary Arterial Hypertension in Systemic Sclerosis
Conditions: Systemic Sclerosis;   Pulmonary Arterial Hypertension
Intervention:
13 Recruiting Investigation of Coronary and Pulmonary Circulatory Parameters in Systemic Sclerosis
Condition: Systemic Sclerosis
Intervention:
14 Recruiting A Clinical Trial of Ambrisentan and Tadalafil in Pulmonary Arterial Hypertension Associated With Systemic Sclerosis
Conditions: Pulmonary Arterial Hypertension;   Systemic Sclerosis;   Scleroderma Spectrum of Diseases;   Connective Tissue Disease;   Pulmonary Hypertension
Interventions: Drug: Tadalafil monotherapy;   Drug: Ambrisentan monotherapy;   Drug: tadalafil and ambrisentan
15 Not yet recruiting Low-Dose Conditioning Followed by Donor Stem Cell Transplant in Treating Patients With Severe Systemic Sclerosis
Condition: Systemic Scleroderma
Interventions: Procedure: nonmyeloablative allogeneic hematopoietic stem cell transplantation;   Drug: fludarabine phosphate;   Radiation: total-body irradiation;   Drug: tacrolimus;   Drug: mycophenolate mofetil;   Other: quality-of-life assessment;   Procedure: peripheral blood stem cell transplantation;   Drug: rituximab;   Drug: cyclophosphamide
16 Recruiting Cyclophosphamide and rATG With Hematopoietic Stem Cell Support in Systemic Scleroderma
Condition: Systemic Scleroderma
Intervention: Procedure: Hematopoietic stem cell support
17 Recruiting Effects of a Personalized Standardized Rehabilitation Program in Systemic Sclerosis
Condition: Systemic Scleroderma
Intervention: Procedure: standardized reeducation and readaptation program
18 Recruiting Mycophenolate Mofetil in Systemic Sclerosis
Condition: Diffuse Cutaneous Systemic Sclerosis
Intervention: Drug: Mycophenolate Mofetil
19 Not yet recruiting Scleroderma: Cyclophosphamide or Transplantation (SCOT) Substudy 02
Conditions: Scleroderma, Systemic;   Sclerosis
Intervention: Procedure: Skin biopsy and blood sampling
20 Recruiting Efficacy and Safety of Imatinib in Scleroderma
Conditions: Scleroderma, Localized;   Scleroderma, Systemic
Intervention: Drug: imatinib mesylate

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