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Found 16 studies with search of: Open Studies | "Scleroderma, Localized"
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1 Recruiting A Protocol Based Treatment for Debilitating Fibrosing Skin Disorders With (Anti-CD 20), Rituximab, Evaluating Safety and Efficacy
Condition: Debilitating Fibrosing Skin Disorders (Localised Scleroderma, Eosinophilic Fasciitis)
Intervention: Drug: Rituximab
2 Not yet recruiting High-Dose Cyclophosphamide and Anti-Thymocyte Globulin Followed by Peripheral Blood Stem Cell Transplant in Treating Patients With Systemic Scleroderma
Condition: Systemic Scleroderma
Interventions: Procedure: peripheral blood stem cell transplantation;   Drug: cyclophosphamide;   Biological: anti-thymocyte globulin;   Other: questionnaire administration;   Other: laboratory biomarker analysis;   Procedure: quality-of-life assessment;   Biological: filgrastim;   Procedure: autologous hematopoietic stem cell transplantation
3 Not yet recruiting Scleroderma: Cyclophosphamide or Transplantation (SCOT) Substudy 03
Conditions: Scleroderma, Systemic;   Sclerosis
Intervention: Procedure: Peripheral blood collection
4 Unknown † Influenza Vaccination in Patients With Scleroderma
Condition: Influenza Vaccine in Scleroderma
Intervention: Biological: Influenza vaccine
5 Recruiting Effect of Sildenafil on the Microcirculatory Blood Flow and Endothelial Progenitor Cells in Systemic Sclerosis
Conditions: Scleroderma, Systemic;   Scleroderma, Diffuse;   Scleroderma, Limited;   Raynaud Phenomenon
Interventions: Drug: Sildenafil citrate;   Drug: Placebo
6 Recruiting IL1-TRAP, Rilonacept, in Systemic Sclerosis
Conditions: Scleroderma;   Systemic Sclerosis;   Diffuse Scleroderma;   Diffuse Systemic Sclerosis
Interventions: Drug: Rilonacept;   Drug: Placebo
7 Unknown † Scleroderma: Cyclophosphamide or Transplantation (SCOT) Substudy 02
Conditions: Scleroderma, Systemic;   Sclerosis
Intervention: Procedure: Skin biopsy and blood sampling
8 Recruiting Autologous Stem Cell Systemic Sclerosis Immune Suppression Trial
Condition: Scleroderma
Interventions: Procedure: Rituximab sandwich regiment followed by SCT;   Procedure: cyclophosphamide regiment followed by SCT
9 Unknown † Genesis of Scleroderma: Role of Environmental Factors in 100 Patients With Scleroderma and 300 Controls
Condition: Scleroderma
Intervention:
10 Recruiting Comparison of Therapeutic Regimens for Scleroderma Interstitial Lung Disease (The Scleroderma Lung Study II)
Conditions: Scleroderma;   Interstitial Lung Disease
Interventions: Drug: Mycophenolate mofetil;   Drug: Cyclophosphamide;   Drug: Placebo
11 Not yet recruiting Study of Pomalidomide (CC-4047) to Evaluate Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Effectiveness for Subjects With Systemic Sclerosis With Interstitial Lung Disease
Conditions: Scleroderma, Systemic;   Sclerosis, Systemic;   Systemic Scleroderma;   Systemic Sclerosis
Interventions: Drug: Pomalidomide (CC-4047);   Drug: Placebo
12 Recruiting Sildenafil Effect on Digital Ulcer Healing in sClerodErma SEDUCE STUDY
Condition: Systemic Scleroderma
Interventions: Drug: Sildenafil;   Drug: placebo
13 Recruiting SCOT Scleroderma Treatment Alternative Registry (STAR Registry)
Conditions: Scleroderma, Systemic;   Sclerosis
Intervention: Behavioral: Telephone Call
14 Recruiting Multi-center, Web Based Observational Study of Pulmonary Hypertension in Scleroderma Patients
Conditions: Systemic Sclerosis;   Scleroderma;   Pulmonary Hypertension;   Pulmonary Arterial Hypertension
Intervention:
15 Unknown † Scleroderma Registry
Conditions: Systemic Sclerosis;   Scleroderma
Intervention:
16 Not yet recruiting Empirical Comparative Study of Variation Blood Level Antibody Vitamin D at Scleroderma (SSc) Patients Compared Healthy Peoples
Condition: Scleroderma
Intervention: Other: Blood sample

† Indicates status has not been verified in more than two years
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