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25 studies found for:    Open Studies | "Retinoblastoma"

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Rank Status Study
1 Recruiting Proton Beam Radiation Therapy for Intraocular and Periocular Retinoblastoma
Condition: Retinoblastoma
Interventions: Radiation: Proton Beam Radiation Therapy;   Procedure: Ophthalmic EUA
2 Recruiting Genetic Mutations and Environmental Exposure in Young Patients With Retinoblastoma and in Their Parents and Young Healthy Unrelated Volunteers
Condition: Retinoblastoma
Interventions: Genetic: DNA ploidy analysis;   Genetic: DNA stability analysis;   Genetic: Southern blotting;   Genetic: genetic linkage analysis;   Genetic: loss of heterozygosity analysis;   Genetic: mutation analysis;   Genetic: polymorphism analysis;   Genetic: reverse transcriptase-polymerase chain reaction;   Other: environmental carcinogenesis study;   Other: questionnaire administration;   Other: study of socioeconomic and demographic variables;   Procedure: evaluation of cancer risk factors;   Procedure: mutation carrier screening
3 Recruiting Cancer Biology of Retinoblastoma
Condition: Retinoblastoma
Intervention:
4 Not yet recruiting Intravitreal Injections of Melphalan for Retinoblastoma
Condition: Retinoblastoma
Intervention: Drug: IVit Melphalan
5 Unknown † Quality of Life in Children Cured of Retinoblastoma
Condition: Retinoblastoma
Intervention:
6 Recruiting Intra-arterial Chemotherapy for the Treatment of Intraocular Retinoblastoma
Condition: Retinoblastoma
Intervention: Drug: Melphalan hydrochloride
7 Unknown † A Study of the Effectiveness of a Local Injection of Chemotherapy for Retinoblastoma
Condition: Retinoblastoma
Intervention: Drug: Melphalan, Carboplatin
8 Unknown † Intra-arterial Chemotherapy for Children With Retinoblastoma
Condition: Retinoblastoma
Interventions: Drug: Intra-arterial injection of melphalan;   Drug: Injection of melphalan into the ophthalmic artery
9 Not yet recruiting Protocol for the Study and Treatment of Participants With Intraocular Retinoblastoma
Condition: Retinoblastoma
Interventions: Drug: vincristine;   Drug: topotecan;   Drug: filgrastim;   Drug: PEG-filgrastim;   Drug: carboplatin;   Other: focal therapy;   Drug: etoposide;   Drug: cyclophosphamide;   Drug: MESNA;   Drug: doxorubicin;   Procedure: enucleation;   Radiation: external beam radiation
10 Recruiting Combination Chemotherapy, Autologous Stem Cell Transplant, and/or Radiation Therapy in Treating Young Patients With Extraocular Retinoblastoma
Condition: Retinoblastoma
Interventions: Biological: filgrastim;   Drug: carboplatin;   Drug: cisplatin;   Drug: cyclophosphamide;   Drug: etoposide;   Drug: thiotepa;   Drug: vincristine sulfate;   Procedure: autologous bone marrow transplantation;   Procedure: autologous hematopoietic stem cell transplantation;   Procedure: peripheral blood stem cell transplantation;   Radiation: radiation therapy
11 Recruiting Intra-arterial Chemotherapy With Melphalan for the Treatment of Retinoblastoma (RTB) in Advanced Intraocular Stage
Condition: Retinoblastoma
Intervention: Drug: Melphalan
12 Recruiting Combination Chemotherapy and Cyclosporine Followed By Cryotherapy and/or Laser Therapy in Treating Patients With Newly Diagnosed Retinoblastoma in Both Eyes
Condition: Retinoblastoma
Interventions: Biological: filgrastim;   Drug: carboplatin;   Drug: cyclosporine;   Drug: etoposide;   Drug: vincristine sulfate;   Procedure: cryosurgery;   Procedure: laser therapy;   Procedure: neoadjuvant therapy
13 Recruiting Molecular Analysis of Retinoblastoma
Condition: Retinoblastoma
Interventions: Other: Tissue samples taken from retinoblastoma;   Other: 5 ml peripheral blood
14 Recruiting Pilot Study of Topotecan/Vincristine With Subconjunctival Carboplatin for Patients With Bilateral Retinoblastoma
Condition: Retinoblastoma
Interventions: Drug: subtenon Carboplatin;   Drug: Topotecan Hydrochloride;   Drug: Vincristine;   Drug: Filgrastim
15 Recruiting Iodine I 131 Monoclonal Antibody 3F8 in Treating Patients With Central Nervous System Cancer or Leptomeningeal Cancer
Conditions: Brain and Central Nervous System Tumors;   Intraocular Melanoma;   Lung Cancer;   Melanoma (Skin);   Metastatic Cancer;   Neuroblastoma;   Ovarian Cancer;   Retinoblastoma;   Sarcoma;   Small Intestine Cancer
Interventions: Genetic: DNA analysis;   Other: immunologic technique;   Other: pharmacological study;   Radiation: iodine I 131 monoclonal antibody 3F8;   Radiation: 131I-3F8
16 Recruiting Seneca Valley Virus-001 and Cyclophosphamide in Treating Young Patients With Relapsed or Refractory Neuroblastoma, Rhabdomyosarcoma, or Rare Tumors With Neuroendocrine Features
Conditions: Adrenocortical Carcinoma;   Gastrointestinal Carcinoid Tumor;   Kidney Cancer;   Neuroblastoma;   Retinoblastoma;   Sarcoma
Interventions: Biological: Seneca Valley virus-001;   Drug: cyclophosphamide;   Other: laboratory biomarker analysis;   Other: pharmacological study
17 Not yet recruiting Anti-Angiogenic Therapy Post Transplant (ASCR) for Relapsed and Refractory Pediatric Solid Tumors
Conditions: Glioma;   Neuroectodermal Tumors, Primitive;   Wilms Tumor;   Rhabdomyosarcoma;   Sarcoma, Ewing;   Osteosarcoma;   Retinoblastoma
Interventions: Other: Control;   Drug: Metronomic Cyclophosphamide;   Drug: Thalomide
18 Recruiting Aflac ST0901 CHOANOME - Sirolimus in Solid Tumors
Conditions: Ewing's Sarcoma;   Osteosarcoma;   Astrocytoma;   Atypical Teratoid/Rhabdoid Tumor;   Ependymoma;   Germ Cell Tumor;   Glioma;   Medulloblastoma;   Rhabdoid Tumor;   Retinoblastoma;   Clear Cell Sarcoma;   Renal Cell Carcinoma;   Wilms Tumor;   Hepatoblastoma;   Neuroblastoma;   Rhabdomyosarcoma
Intervention: Drug: sirolimus
19 Recruiting Use of Racotumomab in Patients With Pediatric Tumors Expressing N-glycolylated Gangliosides
Conditions: Neuroblastoma;   Ewing's Sarcoma;   Wilm's Tumor;   Retinoblastoma;   Glioma
Intervention: Drug: racotumomab
20 Recruiting Comprehensive Omics Analysis of Pediatric Solid Tumors and Establishment of a Repository for Related Biological Studies
Conditions: Sarcoma;   Endocrine Tumors;   Neuroblastoma;   Retinoblastoma;   Renal Cancer
Intervention:
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† Indicates status has not been verified in more than two years