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Found 31 studies with search of: Open Studies | "Neurofibromatoses"
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Rank Status Study
1 Recruiting Topical Rapamycin Therapy to Alleviate Cutaneous Manifestations of Tuberous Sclerosis Complex (TSC) and Neurofibromatosis I (NF1)
Conditions: Tuberous Sclerosis;   Neurofibromatoses;   Angiofibroma;   Neurofibroma
Interventions: Drug: Skincerity;   Drug: Skincerity plus sirolimus/rapamycin;   Drug: Skinercity plus sirolimus/rapamycin
2 Recruiting Sunitinib in Treating Patients With Recurrent or Unresectable Meningioma, Intracranial Hemangiopericytoma, or Intracranial Hemangioblastoma
Conditions: Brain and Central Nervous System Tumors;   Neurofibromatosis Type 1;   Neurofibromatosis Type 2;   Precancerous Condition
Intervention: Drug: sunitinib malate
3 Recruiting Study of Disease Severity in Adults With Neurofibromatosis Type 1 (NF1)
Condition: Neurofibromatosis Type I
Intervention:
4 Recruiting Neurofibromatosis Type 1 (NF1) and Tibial Dysplasia
Conditions: Neurofibromatosis Type 1;   Tibial Dysplasia
Intervention:
5 Recruiting PTC299 for Treatment of Neurofibromatosis Type 2
Condition: Neurofibromatosis 2
Intervention: Drug: PTC299
6 Recruiting Spinal Abnormalities in Neurofibromatosis Type 1 (NF1)
Condition: Neurofibromatosis Type 1
Intervention:
7 Recruiting Natural History Study of Patients With Neurofibromatosis Type I
Conditions: Neurofibromatosis Type 1;   Malignant Peripheral Nerve Sheath Tumor;   Plexiform Neurofibroma;   Optic Glioma;   Neurofibroma
Intervention:
8 Recruiting Trial to Evaluate the Safety of Lovastatin in Individuals With Neurofibromatosis Type I (NF1)
Condition: Neurofibromatosis 1
Interventions: Drug: Lovastatin;   Drug: placebo pill
9 Recruiting A Randomized Placebo-Controlled Study of Lovastatin in Children With Neurofibromatosis Type 1
Condition: Neurofibromatosis Type 1
Interventions: Drug: Lovastatin ™;   Device: placebo
10 Recruiting Multi-Center Project: Spinal Abnormalities in Neurofibromatosis Type1 (NF1) Patients
Condition: Neurofibromatosis Type 1
Intervention:
11 Recruiting Sirolimus in Treating Patients With Neurofibromatosis Type 1 and Plexiform Neurofibromas That Cannot Be Removed By Surgery
Conditions: Neurofibromatosis Type 1;   Precancerous Condition
Intervention: Drug: sirolimus
12 Recruiting NF1-Attention: Study of Children With Neurofibromatosis Type 1 Treated by Methylphenidate
Condition: Neurofibromatosis Type 1
Intervention: Drug: methylphenidate
13 Recruiting AZD2171 in Treating Patients With Neurofibromatosis Type 1 and Plexiform Neurofibroma and/or Neurofibroma Near the Spine
Conditions: Neurofibromatosis Type 1;   Precancerous Condition
Intervention: Drug: cediranib maleate
14 Recruiting A Phase II Study of the mTOR Inhibitor Sirolimus in Neurofibromatosis Type 1 Related Plexiform Neurofibromas
Condition: Neurofibromatosis Type 1
Intervention: Drug: Sirolimus, Rapamycin
15 Recruiting PEG-Interferon Alfa-2b in Treating Young Patients With Unresectable Plexiform Neurofibromas Associated With Neurofibromatosis Type 1
Conditions: Neurofibromatosis Type 1;   Precancerous Condition
Intervention: Biological: PEG-interferon alfa-2b
16 Recruiting Sorafenib in Treating Young Patients With Neurofibromatosis Type 1 and Plexiform Neurofibromas That Cannot Be Removed by Surgery
Conditions: Neurofibromatosis Type 1;   Precancerous Condition
Interventions: Drug: sorafenib tosylate;   Other: laboratory biomarker analysis;   Other: pharmacological study;   Other: questionnaire administration;   Procedure: quality-of-life assessment
17 Recruiting Ranibizumab for Neurofibromas Associated With Neurofibromatosis 1
Conditions: Neurofibromatosis Type 1;   Cutaneous Neurofibromas
Intervention: Drug: Ranibizumab
18 Recruiting Topical Imiquimod 5% Cream for Treatment of Cutaneous Neurofibromas in Adults With Neurofibromatosis 1
Conditions: Neurofibromatosis Type 1;   Cutaneous Neurofibromas
Intervention: Drug: Imiquimod 5% Cream
19 Recruiting Combination Chemotherapy in Treating Patients With Neurofibromatosis and Progressive Plexiform Neurofibromas
Conditions: Neurofibromatosis Type 1;   Precancerous Condition
Interventions: Drug: methotrexate;   Drug: vinblastine
20 Recruiting Fludeoxyglucose F 18 Positron Emission Tomography and Magnetic Resonance Perfusion Imaging in Patients With Neurofibromatosis 1 and Plexiform Neurofibroma
Conditions: Neurofibromatosis Type 1;   Precancerous Condition
Interventions: Procedure: magnetic resonance imaging;   Procedure: positron emission tomography;   Procedure: radionuclide imaging;   Radiation: fludeoxyglucose F 18;   Radiation: gadopentetate dimeglumine

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