81 studies found for:    Open Studies | "Lacrimal Apparatus Diseases"
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Rank Status Study
1 Unknown  Pilot Study of a Homeopathic Therapy in Combination With Cyclosporin (Restasis) in the Treatment of Dry Eye Disease
Condition: Dry Eye Syndromes
Interventions: Drug: euphrasia based homeopathic therapy and cyclosporin;   Drug: cyclosporin solution
2 Recruiting Safety and Efficacy of rhNGF Eye Drops at Different Doses in Patients With Dry Eye
Condition: Dry Eye Syndrome.
Interventions: Biological: Human nerve growth factor 20 µg/mL;   Biological: Human nerve growth factor 4 µg/mL or 60 µg/mL
3 Recruiting Ocular Surface Immune Response in Dry Eye Disease: Analysis of Conjunctival and Peripheral Corneal Immune Cell Alterations by In Vivo Confocal Microscopy and Clinical Correlation
Condition: Dry Eye Disease
Intervention: Other: In vivo confocal microscopy (IVCM)
4 Recruiting PD of VAY736 in Patients With Primary Sjögren's Syndrome
Condition: Primary Sjögren's Syndrome
Interventions: Drug: VAY736;   Drug: Placebo
5 Recruiting The Effect of Intravenous Glucocorticoids on the Tearfilm in Eyes With Thyroid-associated Ophthalmopathy
Conditions: Thyroid-associated Ophthalmopathy;   Dry Eye Syndrome
Interventions: Drug: Methylprednisolone;   Drug: Esomeprazole
6 Recruiting Efficacy of Pulsed Light Therapy for Meibomian Gland Dysfunction and Dry Eye Syndrome
Conditions: Meibomian Gland Dysfunction;   Dry Eye Syndrome
Interventions: Device: Cutera Xeo Platform-Limelight;   Device: Sciton BroadBand Light
7 Not yet recruiting Dry Eye Assessment and Management Study
Condition: Dry Eye
Interventions: Drug: Omega-3 supplements;   Drug: Placebo
8 Recruiting Efficacy and Safety of XG-104 for the Treatment of Dry Eye
Condition: Dry Eye
Interventions: Drug: XG-104;   Drug: Placebo
9 Recruiting Efficacy and Safety of PRO-148 Versus Systane®, in Patients With Mild to Moderate Dry Eye
Condition: Dry Eye
Interventions: Drug: PRO-148;   Drug: Systane
10 Recruiting Regulatory B Cells in Inflammatory Rheumatisms and Biomarkers of Response to Biologic Treatments
Conditions: Rheumatoid Arthritis;   Healthy Subjects;   Osteoarthritis;   Auto-immune Disease;   Lupus;   Systemic Sclerosis;   Sjögren Syndrome;   Spondylitis;   Crystal Rheumatisms
Intervention: Other: Comparison of Bregs levels
11 Recruiting Safety and Efficacy Study of R932348 Ophthalmic Solution in Chronic Ocular Graft Versus Host Disease Patients(DROPS-2)
Condition: Chronic Graft-versus-host Disease
Interventions: Drug: R348 Ophthalmic Solution, 0.2%;   Drug: R348 Ophthalmic Solution, 0.5%;   Other: Placebo Ophthalmic Solution
12 Recruiting Efficacy and Safety of Fluorometholone (FML) in Dry Eye Disease (Keratoconjunctivitis Sicca)
Condition: Dry Eye
Interventions: Drug: FML 0.1% eyedrops;   Drug: Liquifilm artificial tears eyedrops
13 Recruiting The Pathogenesis and Natural History of Sjogren s Syndrome
Conditions: Pathogenesis;   Sjogren's Syndrome;   Salivary Gland
Intervention:
14 Unknown  Efficacy of FreshKote and Systane for the Treatment of Dry Eye and Improvement of Osmolarity
Condition: Dry Eye
Interventions: Drug: FreshKote;   Drug: Systane
15 Recruiting The Research Registry for Neonatal Lupus
Conditions: Neonatal Lupus;   Systemic Lupus Erythematosus;   Sjogren's Syndrome;   Congenital Heart Block
Intervention: Other: No intervention; observational
16 Recruiting Efficacy and Safety of T2762 and Vismed® in Dry Eye Syndrome
Condition: Dry Eye Syndrome
Interventions: Device: T2762;   Device: Vismed®
17 Recruiting Study of Cyclosporine Ophthalmic Soution Group and Cyclosporine Ophthalmic Suspension Group
Condition: Dry Eye Syndromes
Intervention: Drug: Cyclosporine ophthalmic solution
18 Recruiting Functional Impairment of Reading Ability in Dry Eye Patients and Effects of Sustained Reading on the Ocular Surface
Condition: Dry Eye Syndromes
Intervention: Other: 30 minutes sustained reading
19 Recruiting Omalizumab for Lupus
Conditions: Systemic Lupus Erthematosus;   Sjogren's Syndrome
Interventions: Drug: Omalizumab;   Drug: Placebo
20 Recruiting A Phase IV, Randomized, Parallel Group, Investigator-Masked Evaluation of the Effect of Loteprednol Etabonate Ophthalmic Gel 0.5% on the Initiation of Dry Eye Treatment With Restasis®
Condition: Dry Eye Disease
Interventions: Drug: Loteprednol etabonate;   Drug: Artificial Tears;   Drug: Restasis

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Indicates status has not been verified in more than two years