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9 studies found for:    Open Studies | "Histamine Antagonists"

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Rank Status Study
1 Recruiting Impact of Omalizumab on Quality of Life Measures and Angioedema Occurrence in Patients With CSU Refractory to Therapy
Conditions: Diagnosis of Chronic Spontaneous Urticaria (CSU) Refractory to H1-antihistamine Treatment;   Presence of Itch an Hives for More Than 6 Weeks;   UAS7 Score of More Than 14 (Range 0-42);   Patient Has History of Insufficient Response to 4x of the Approved Dose of H1-antihistamines;   CSU Diagnosis for More Than 6 Months;   Angioedema at Least 4x in the Last 6 Months
Interventions: Biological: Omalizumab;   Drug: Placebo
2 Not yet recruiting Study of Using Long Acting Antihistamine to Treat Opioid Induced Itching
Condition: Pruritus
Interventions: Drug: Cetirizine;   Drug: Placebo or sugar pill
3 Recruiting Mode of Action Study of Omalizumab in Patients With Chronic Idiopathic Urticaria (CIU) Who Fail to Respond to Antihistamine Treatment
Condition: Chronic Idiopathic Urticaria
Interventions: Drug: IGE025;   Drug: placebo
4 Recruiting Cold Urticaria Treatment With Xolair
Condition: Cold Contact Urticaria
Interventions: Drug: Omalizumab;   Drug: Placebo
5 Not yet recruiting Effects of Levocetirizine and Hydroxyzine on Cognitive and Psychomotor Functioning During Simulated Diving
Condition: Healthy Volunteers
Interventions: Drug: Levocetirizine;   Drug: Hydroxyzine;   Drug: Placebo
6 Recruiting Levocetirizine Plus Bed-Time Hydroxyzine in the Management of Corticodependent Chronic Urticaria Versus Both Drugs Alone in High Doses
Condition: Chronic Urticaria
Interventions: Drug: Levocetirizine;   Drug: Hydroxyzine;   Drug: Levocetirizine plus Hydroxyzine
7 Not yet recruiting Refractory Eustachian Tube Dysfunction: Are the Symptoms Related to Endolymphatic Hydrops
Conditions: Eustachian Tube Dysfunction;   Endolymphatic Hydrops
Interventions: Drug: Nasal steroid;   Procedure: Myringotomy tube placement;   Drug: Diuretic;   Drug: Antihistamine;   Behavioral: Low salt diet
8 Recruiting NOLAN: Naproxen or Loratadine and Neulasta
Condition: Bone Pain in Stage I - III Breast Cancer
Interventions: Drug: Naproxen;   Drug: Loratadine
9 Recruiting Efficacy and Safety of PRO-118 Ophthalmic Solution in Allergic Conjunctivitis
Conditions: Ocular Itching;   Ocular Allergy;   Seasonal Allergic Conjunctivitis;   Perennial Allergic Conjunctivitis;   Conjunctivitis, Allergic
Interventions: Drug: PRO-118 Ophthalmic Solution 0.015%;   Drug: PRO-118 Ophthalmic Solution 0.015 %;   Drug: PRO-118 Ophthalmic Solution 0.020 %;   Drug: Placebo Ophthalmic Solution
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† Indicates status has not been verified in more than two years