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Found 425 studies with search of: Open Studies | "Glioma"
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Rank Status Study
1 Recruiting A Pilot Study of Glioma Associated Antigen Vaccines in Conjunction With Poly-ICLC in Pediatric Gliomas
Conditions: Newly Diagnosed Pediatric Pontine Glioma.;   Newly Diagnosed Pediatric High Grade Glioma.;   Recurrent Pediatric High Grade Glioma.;   Recurrent Pediatric Low Grade Glioma.
Interventions: Biological: HLA-A2 restricted synthetic glioma antigen peptides vaccine;   Drug: Poly ICLC;   Genetic: Reverse transcriptase-polymerase chain reaction;   Other: enzyme-linked immunosorbent assay;   Other: flow cytometry;   Other: immunohistochemistry staining method;   Other: laboratory biomarker analysis
2 Recruiting Molecular Analysis of Samples From Patients With Diffuse Intrinsic Pontine Glioma and Brainstem Glioma
Conditions: Diffuse Intrinsic Pontine Glioma;   Brainstem Glioma
Intervention:
3 Recruiting Lenalidomide and Radiation Therapy in High Grade Gliomas or Diffuse Intrinsic Pontine Gliomas
Conditions: Diffuse Intrinsic Pontine Glioma;   Anaplastic Astrocytoma;   High Grade Glioma
Interventions: Drug: Lenalidomide;   Radiation: Radiation Therapy
4 Recruiting PDGFR Inhibitor Crenolanib in Children/Young Adults With Diffuse Intrinsic Pontine Glioma or Recurrent High-Grade Glioma
Conditions: Diffuse Intrinsic Pontine Glioma;   Progressive or Refractory High-Grade Glioma
Intervention: Drug: Crenolanib
5 Recruiting A Pilot Feasibility Study of Oral 5-Fluorocytosine and Genetically-Modified Neural Stem Cells Expressing E.Coli Cytosine Deaminase for Treatment of Recurrent High Grade Gliomas
Conditions: Adult Anaplastic Astrocytoma;   Recurrent Grade III Glioma;   Recurrent Grade IV Glioma;   Adult Anaplastic Oligodendroglioma;   Adult Brain Tumor;   Adult Giant Cell Glioblastoma;   Adult Glioblastoma;   Adult Gliosarcoma;   Adult Mixed Glioma;   Recurrent Adult Brain Tumor;   Adult Anaplastic Oligoastrocytoma;   Recurrent High Grade Glioma
Interventions: Drug: flucytosine;   Other: polymerase chain reaction;   Other: immunohistochemistry staining method;   Biological: gene therapy;   Other: pharmacological study;   Other: 3-Tesla magnetic resonance imaging;   Other: laboratory biomarker analysis;   Procedure: therapeutic conventional surgery;   Biological: E. coli CD-expressing genetically modified neural stem cells
6 Recruiting AZD6244 in Children With Low-Grade Gliomas
Conditions: Optic Glioma;   Pilocytic Astrocytoma;   Low Grade Glioma;   Fibriullary Astrocytoma
Intervention: Drug: AZD6244
7 Recruiting Hypofractionated Stereotactic Radiotherapy With Bevacizumab in the Treatment of Recurrent Malignant Glioma
Conditions: Brain Cancer;   MALIGNANT GLIOMA;   Glioblastoma;   Anaplastic Astrocytoma (AA);   Anaplastic Oligodendroglioma (AO);   Anaplastic Oligo-astrocytoma (AOA);   Anaplastic Mixed Gliomas;   Malignant Glioma NOS
Intervention: Other: Bevacizumab & stereotactic radiotherapy
8 Recruiting Valproic Acid and Radiation Followed by Maintenance Valproic Acid and Bevacizumab in Children With High Grade Gliomas
Conditions: Glial Cell Tumors;   Malignant Gliomas;   Glioblastoma Multiforme;   Anaplastic Astrocytoma;   Gliomatosis Cerebri;   Gliosarcoma;   Brainstem Glioma
Interventions: Drug: Valproic acid;   Drug: Bevacizumab;   Radiation: Radiation therapy
9 Recruiting A Study of Bevacizumab Therapy in Patients With Newly Diagnosed High-Grade Gliomas and Diffuse Intrinsic Pontine Gliomas
Conditions: Newly Diagnosed High-Grade Gliomas;   Diffuse Intrinsic Pontine Glioma
Interventions: Drug: Temozolomide;   Drug: Bevacizumab;   Drug: Irinotecan
10 Recruiting Phase I Study of Cellular Immunotherapy for Recurrent/Refractory Malignant Glioma Using Intratumoral Infusions of GRm13Z40-2, An Allogeneic CD8+ Cytolitic T-Cell Line Genetically Modified to Express the IL 13-Zetakine and HyTK and to be Resistant to Glucocorticoids, in Combination With Interleukin-2
Conditions: Anaplastic Astrocytoma;   Anaplastic Ependymoma;   Anaplastic Meningioma;   Anaplastic Oligodendroglioma;   Brain Stem Glioma;   Ependymoblastoma;   Giant Cell Glioblastoma;   Glioblastoma;   Gliosarcoma;   Grade III Meningioma;   Meningeal Hemangiopericytoma;   Mixed Glioma;   Pineal Gland Astrocytoma;   Brain Tumor
Interventions: Biological: therapeutic allogeneic lymphocytes;   Biological: aldesleukin;   Other: laboratory biomarker analysis;   Procedure: positron emission tomography
11 Recruiting AZD8055 for Adults With Recurrent Gliomas
Conditions: Glioblastoma Multiforme;   Anaplastic Astrocytoma;   Anaplastic Oligodendroglioma;   Malignant Glioma;   Brainstem Glioma
Intervention: Drug: AZD8055
12 Recruiting Fluorine F 18 Fluorodopa-Labeled PET Scan in Planning Surgery and Radiation Therapy in Treating Patients With Newly Diagnosed High- or Low-Grade Malignant Glioma
Conditions: Adult Anaplastic Astrocytoma;   Adult Anaplastic Ependymoma;   Adult Anaplastic Oligodendroglioma;   Adult Brain Stem Glioma;   Adult Diffuse Astrocytoma;   Adult Ependymoma;   Adult Giant Cell Glioblastoma;   Adult Glioblastoma;   Adult Gliosarcoma;   Adult Mixed Glioma;   Adult Myxopapillary Ependymoma;   Adult Oligodendroglioma;   Adult Pilocytic Astrocytoma;   Adult Pineal Gland Astrocytoma;   Adult Subependymal Giant Cell Astrocytoma;   Adult Subependymoma
Interventions: Procedure: biopsy;   Procedure: computed tomography;   Procedure: therapeutic conventional surgery;   Radiation: radiation therapy treatment planning/simulation;   Radiation: radiation therapy;   Procedure: magnetic resonance imaging;   Procedure: positron emission tomography;   Drug: fluorine F 18 fluorodopa
13 Recruiting Everolimus (RAD001) for Children With Chemotherapy-Refractory Progressive or Recurrent Low-Grade Gliomas
Conditions: Glioma;   Low-grade Glioma
Intervention: Drug: RAD001
14 Recruiting Proton Beam Radiation Therapy in Treating Patients With Low Grade Gliomas
Conditions: Adult Brain Tumor;   Adult Brain Stem Glioma;   Adult Diffuse Astrocytoma;   Adult Ependymoma;   Adult Grade II Meningioma;   Adult Melanocytic Lesion;   Adult Meningeal Hemangiopericytoma;   Adult Mixed Glioma;   Adult Oligodendroglioma;   Adult Pineal Gland Astrocytoma;   Adult Pineocytoma;   Recurrent Adult Brain Tumor
Interventions: Radiation: proton beam radiation therapy;   Procedure: quality-of-life assessment;   Other: questionnaire administration
15 Recruiting Plerixafor (AMD3100) and Bevacizumab for Recurrent High-Grade Glioma
Conditions: High Grade Glioma: Glioblastoma (GBM);   High Grade Glioma: Gliosarcoma;   Anaplastic Astrocytoma (AA);   Anaplastic Oligodendroglioma (AO);   Mixed Anaplastic Oligoastrocytoma (AOA)
Interventions: Drug: Plerixafor;   Drug: Bevacizumab;   Procedure: Surgery
16 Recruiting An Open Label Dose Escalation Safety Study of Convection-Enhanced Delivery of IL13-PE38QQR in Patients With Progressive Pediatric Diffuse Infiltrating Brainstem Glioma and Supratentorial High-grade Glioma
Conditions: Brain Neoplasm;   Glioma
Intervention: Drug: IL13-PE38QQR
17 Recruiting A Study of XL765 (SAR245409) in Combination With Temozolomide With and Without Radiation in Adults With Malignant Gliomas
Conditions: Mixed Gliomas;   Malignant Gliomas;   Glioblastoma Multiforme
Interventions: Drug: XL765 (SAR245409);   Drug: Temozolomide
18 Recruiting Proton Radiation Therapy for Low Grade Gliomas
Conditions: Low Grade Gliomas;   Protoplasmic Astrocytomas;   Fibrillary Astrocytomas;   Gemistocytic Astrocytomas;   Oligoastrocytomas;   Oligodendrogliomas;   Other WHO Grade II/IV Gliomas
Intervention: Radiation: Proton radiation
19 Recruiting Identification of Clinically Occult Glioma Cells and Characterization of Glioma Behavior Through Machine Learning Analysis of Advanced Imaging Technology
Condition: Glioma
Interventions: Procedure: MRS Imaging;   Procedure: PET Scanning;   Procedure: Diffusion Tensor Imaging
20 Recruiting A Study of Aminolevulinic Acid Used to Enhance Visualization and Surgical Removal of Brain Tumors
Conditions: Malignant Glioma;   Glioma;   Glioblastoma;   Glioblastoma Multiforme;   Astrocytoma
Intervention: Drug: Aminolevulinic Acid

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