41 studies found for:    Open Studies | "Down Syndrome"
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Rank Status Study
1 Recruiting Down Syndrome Metabolic Health Study
Conditions: Down Syndrome;   Trisomy 21
Intervention:
2 Recruiting Nicotine Treatment of Cognitive Decline in Down Syndrome
Conditions: Down Syndrome;   Mild Cognitive Impairment
Interventions: Drug: Low Dose Nicotine (7mg);   Drug: Moderate Dose Nicotine (14mg)
3 Recruiting Treatment Trial of Subclinical Hypothyroidism in Down Syndrome
Conditions: Down Syndrome;   Subclinical Hypothyroidism
Intervention: Drug: Levothyroxine
4 Unknown  History of Amyloid Deposition in Adults With Down Syndrome
Conditions: Down Syndrome;   Amyloid Deposition;   Alzheimers Disease
Intervention:
5 Recruiting Computer Models of Airways in Children and Young Adults With Sleep Apnea and Down Syndrome
Conditions: Down Syndrome;   Obstructive Sleep Apnea
Intervention:
6 Recruiting Obstructive Sleep Apnea and Neurocognitive and Cardiovascular Function in Children With Down Syndrome
Conditions: Down Syndrome;   Obstructive Sleep Apnea Syndrome
Interventions: Device: Continuous positive airway pressure;   Device: Sham or placebo continuous positive airway pressure
7 Recruiting Evaluation of a Simplified Method for Diagnosis of Sleep Apnea in Children and Adults With Down Syndrome
Condition: Down Syndrome
Intervention: Other: Polysomnography
8 Unknown  Trends in Intellectual Development in Down Syndrome
Condition: Down Syndrome
Intervention:
9 Recruiting Down Syndrome and Continuous Positive Pressure Therapy
Conditions: Down Syndrome;   Obstructive Sleep Apnea Syndrome
Intervention: Device: Continuous Positive Pressure
10 Recruiting DS-Connect {TM}: The Down Syndrome Registry
Condition: Down Syndrome
Intervention:
11 Recruiting Gait Parameters of Persons With Down Syndrome With and Without Orthotics Using GaitRite
Condition: Down Syndrome
Intervention: Procedure: custom orthotics
12 Recruiting Efficacy Assessment of Systematic Treatment With Folinic Acid and Thyroid Hormone on Psychomotor Development of Down Syndrome Young Children
Condition: Down Syndrome
Intervention: Drug: thyroid hormone and folinic acid
13 Recruiting A Double-blind, Placebo-controlled Comparative Study and Open-label Extension Study to Confirm the Efficacy and Safety of E2020 in Subjects With Down Syndrome Having Regression Symptoms and Disabled Activities of Daily Living.
Condition: Down Syndrome
Interventions: Drug: E2020-Donepezil hydrochloride;   Drug: Placebo
14 Unknown  Natural History of Amyloid Deposition in Adults With Down Syndrome
Condition: Down Syndrome
Intervention:
15 Not yet recruiting Intensive Dysarthria Sessions in Adults and Children With Down Syndrome
Conditions: Dysarthria;   Down Syndrome
Intervention: Behavioral: Speech sessions
16 Unknown  Amyloid Plaque and Tangle Imaging in Alzheimer's Disease and Down Syndrome
Conditions: Down Syndrome;   Alzheimer's Disease
Intervention:
17 Unknown  Neuromuscular Characteristics of Individuals With Down Syndrome (DS)
Condition: Down Syndrome
Intervention: Other: muscle strength
18 Not yet recruiting Trisomy 21 in Adulthood
Condition: Down Syndrome
Intervention: Genetic: karyotype
19 Unknown  Glucose Metabolic, Amyloid, and Tau Brain Imaging in Down Syndrome and Dementia
Conditions: Down Syndrome;   Alzheimer's Disease
Intervention:
20 Not yet recruiting A Study of RG1662 in Adults and Adolescents With Down Syndrome (CLEMATIS)
Condition: Down Syndrome
Interventions: Drug: RG1662;   Drug: Placebo

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Indicates status has not been verified in more than two years