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Found 217 studies with search of: "gene therapy"
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Rank Status Study
1 Recruiting rAd-p53 Gene Therapy for Advanced Malignant Thyroid Tumors
Condition: Advanced Malignant Thyroid Tumors
Interventions: Drug: rAd-p53 gene;   Procedure: surgery;   Drug: p53 gene therapy;   Radiation: p53 gene therapy with radioactive iodine
2 Completed Study of Intra-articular Delivery of tgAAC94 in Inflammatory Arthritis Subjects
Conditions: Arthritis, Rheumatoid;   Arthritis, Psoriatic;   Ankylosing Spondylitis
Interventions: Genetic: tgAAC94 gene therapy vector;   Genetic: tgAAC94 placebo
3 Recruiting rAd-p53 Gene Therapy for Advanced Oral and Maxillofacial Malignant Tumors
Condition: Advanced Oral and Maxillofacial Malignant Tumors
Interventions: Drug: p53 gene with surgery;   Procedure: surgery;   Drug: p53 with chemotherapy;   Drug: p53 gene therapy
4 Recruiting Gene Therapy of Pancreatic Ductal Adenocarcinoma
Condition: Gene Therapy in Pancreatic Adenocarcinoma
Intervention: Genetic: Gene Therapy product CYL-02 = plasmid DNA pre-complexed to linear polyethylenimine encoding sst2 + dck::umk genes
5 Recruiting Gene Therapy for WAS
Condition: Wiskott-Aldrich Syndrome
Intervention: Biological: ex vivo gene therapy
6 Recruiting Gene Therapy for Wiskott-Aldrich Syndrome (WAS)
Condition: Wiskott-Aldrich Syndrome
Intervention: Biological: ex vivo gene therapy
7 Completed Liver Transplantation With ADV-TK Gene Therapy Improves Survival in Patients With Advanced Hepatocellular Carcinoma
Conditions: Hepatocellular Carcinoma;   Liver Transplantation
Intervention: Genetic: ADV-TK (adenovirus-thymidine kinase enzyme) gene therapy
8 Not yet recruiting rAd-p53 Gene Combined With Chemotherapy in Treatment Advanced Non-small-cell Carcinoma
Condition: Non-small Cell Lung Cancer
Interventions: Drug: rAd-p53 gene therapy plus chemotherapy;   Drug: chemotherapy
9 Completed Gene Therapy for ADA-SCID
Condition: Severe Combined Immunodeficiency Syndrome
Intervention: Genetic: gene transduced PBL and/or gene transduced HSC
10 Completed Gene Therapy in Treating Patients With Primary Brain Tumors
Condition: Brain and Central Nervous System Tumors
Interventions: Biological: gene therapy;   Drug: chemotherapy;   Drug: ganciclovir;   Procedure: conventional surgery
11 Completed Gene Therapy for Gyrate Atrophy
Condition: Gyrate Atrophy
Intervention: Procedure: Gene therapy
12 Completed Gene Therapy for Chronic Granulomatous Diseases - Long-term Follow-up
Conditions: Chronic Granulomatous Disease;   Communicable Disease
Interventions: Drug: Gene Therapy Method for CGD;   Device: Isolex 300i Magnetic Cell Selector
13 Active, not recruiting Randomized Trial of Suicide Gene Therapy and Prostate Cancer
Condition: Prostate Cancer
Interventions: Biological: Ad5-yCD/mutTKSR39rep-ADP;   Radiation: IMRT
14 Completed Clinical Study of AAV1-gamma-sarcoglycan Gene Therapy for Limb Girdle Muscular Dystrophy Type 2C
Conditions: Limb Girdle Muscular Dystrophy Type 2C;   Gamma-sarcoglycanopathy
Intervention: Biological: AAV1-gamma-sarcoglycan vector injection
15 Recruiting EndocardialVascularEndothelialGrowth Factor D(VEGF-D)Gene Therapy for the Treatment of Severe Coronary Heart Disease
Conditions: Angina Pectoris;   Myocardial Infarction
Intervention: Biological: VEGF-D gene transfer
16 Completed Phase 1 Dose Escalation Study of Intra-Articular Administration of tgAAC94
Condition: Rheumatoid Arthritis
Interventions: Genetic: tgAAC94 gene therapy vector;   Genetic: tgAAC94 placebo
17 Active, not recruiting Combination Chemotherapy Plus Gene Therapy in Treating Patients With CNS Tumors
Conditions: Bone Marrow Suppression;   Brain and Central Nervous System Tumors;   Drug/Agent Toxicity by Tissue/Organ
Interventions: Procedure: filgrastim;   Biological: gene therapy;   Drug: lomustine;   Drug: procarbazine hydrochloride;   Drug: vincristine sulfate;   Procedure: in vitro-treated peripheral blood stem cell transplantation
18 Active, not recruiting Gene Therapy-Treated Stem Cells in Treating Patients Undergoing Stem Cell Transplant for Intermediate-Grade or High-Grade AIDS-Related Lymphoma
Condition: Lymphoma
Interventions: Biological: filgrastim;   Biological: gene therapy;   Drug: carmustine;   Drug: cyclophosphamide;   Drug: etoposide;   Procedure: autologous hematopoietic stem cell transplantation;   Procedure: in vitro-treated peripheral blood stem cell transplantation
19 Completed Phase I Study of Ex Vivo Liver-Directed Gene Therapy for Familial Hypercholesterolemia
Condition: Familial Hypercholesterolemia
Intervention: Procedure: gene therapy
20 Recruiting Safety Study of Recombinant Adeno-Associated Virus Acid Alpha-Glucosidase to Treat Pompe Disease
Condition: Pompe Disease
Intervention: Drug: rAAV1-CMV-GAA

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