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Found 23 studies with search of: "alpha-1 antitrypsin deficiency"
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Rank Status Study
1 Active, not recruiting The Use of High Resolution Chest Computed Tomography in Alpha-1 Antitrypsin Deficiency
Condition: Alpha-1 Antitrypsin Deficiency
Intervention:
2 Completed Phase II/III Study of an Alpha-1 Proteinase Inhibitor (Kamada-API) in Individuals With Alpha-1 Antitrypsin Deficiency
Condition: Alpha 1-Antitrypsin Deficiency
Intervention: Drug: Kamada-API
3 Recruiting Management of Patients With Alpha-1 Antitrypsin Deficiency Associated Emphysema
Conditions: Alpha 1-Antitrypsin Deficiency;   Emphysema
Intervention:
4 Completed Safety Study of an Aerosolized, Recombinant Alpha 1-Antitrypsin in Subjects With Alpha 1-Antitrypsin Deficiency
Condition: Alpha 1-Antitrypsin Deficiency
Intervention: Drug: Aerosolized, Recombinant Alpha 1-Antitrypsin
5 Completed Study of the Effect of Aerosolized, Recombinant Alpha 1-Antitrypsin on Epithelial Lining Fluid Analytes in Subjects With Alpha 1-Antitrypsin Deficiency
Condition: Alpha 1-Antitrypsin Deficiency
Intervention: Drug: Aerosolized, Recombinant Alpha 1-Antitrypsin
6 Enrolling by invitation Extension Study of Zemaira i.v. Administration in Subjects With Emphysema Due to alpha1-Proteinase Inhibitor Deficiency.
Conditions: Emphysema;   Alpha 1-Proteinase Inhibitor Deficiency
Intervention: Biological: Alpha 1- proteinase inhibitor [human]
7 Completed Aralast alpha1-Proteinase Inhibitor Surveillance Study
Condition: Alpha 1-Antitrypsin Deficiency
Intervention: Drug: ARALAST Fraction IV-1 Alpha1-Proteinase Inhibitor
8 Completed Efficacy and Safety Study of Augmentation Therapy With Aralast (Human Alpha 1 - Proteinase Inhibitor)
Condition: Alpha 1-Antitrypsin Deficiency
Intervention: Drug: ARALAST Fraction IV-1 Alpha1-Proteinase Inhibitor (ARALAST Fr. IV-1)
9 Recruiting Zemaira in Subjects With Emphysema Due to Alpha1-Proteinase Inhibitor (API) Deficiency
Conditions: Alpha1-proteinase Inhibitor Deficiency;   Emphysema
Interventions: Biological: Alpha1-proteinase inhibitor;   Other: Placebo
10 Terminated Study of Genotype and Phenotype in Patients With Alpha 1-Antitrypsin Deficiency
Condition: Alpha 1-Antitrypsin Deficiency
Intervention:
11 Completed Alpha-1-Antitrypsin (AAT) To Treat Emphysema In AAT-Deficient Patients (EXACTLE)
Condition: Alpha 1-Antitrypsin Deficiency
Interventions: Drug: Alpha1-Proteinase Inhibitor (Human);   Drug: Albumin (Human) 20%, USP
12 Completed Alpha1-Antitrypsin Deficiency Registry
Conditions: Lung Diseases;   Emphysema;   Alpha-1 Antitrypsin Deficiency;   Chronic Obstructive Pulmonary Disease
Intervention:
13 Completed The Comparison of the Pharmacokinetic, Safety and Tolerability of Alpha-1 MP and Prolastin In Adult Alpha1-Antitrypsin Deficient Patients
Condition: Alpha 1-Antitrypsin Deficiency
Intervention: Drug: alpha-1 proteinase inhibitor (human)
14 Completed Pharmacokinetic Study of Aralast (Human Alpha1- PI)
Condition: Alpha 1-Antitrypsin Deficiency
Intervention: Drug: ARALAST Fraction IV-1 Alpha1-Proteinase Inhibitor (ARALAST Fr. IV-1)
15 Active, not recruiting Experimental Gene Transfer Procedure to Treat Alpha 1-Antitrypsin Deficiency
Condition: Alpha 1-Antitrypsin Deficiency
Intervention: Genetic: rAAV2-CB-hAAT Gene Vector
16 Active, not recruiting Experimental Gene Transfer Procedure to Treat Alpha 1-Antitrypsin Deficiency
Condition: Alpha 1-Antitrypsin Deficiency
Intervention: Biological: rAAV1-CB-hAAT
17 Completed 4-PBA: Will it Increase the Level of Alpha 1-Antitrypsin(AAT) in Persons With AAT Deficiency?
Condition: Alpha 1-Antitrypsin Deficiency
Intervention: Drug: 4 Phenyl Butyrate (4PBA)
18 Recruiting Alpha-1 Coded Testing Study (ACT Trial)
Condition: Alpha 1-Antitrypsin Deficiency
Intervention: Procedure: Alpha-1 Antitrypsin Genotype
19 Recruiting Alpha-1 Foundation Research Registry
Condition: Alpha 1-Antitrypsin Deficiency
Intervention:
20 Completed Characterization of the Pathobiology of Early Lung Destruction in Alpha 1-Antitrypsin Deficient Individuals
Conditions: Emphysema;   Lung Diseases, Obstructive;   Alpha 1-Antitrypsin Deficiency
Intervention:

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