Ventricular Pace Suppression Versus Intrinsic Rhythm Support Study (VIPERS)

Inclusion Criteria:

• Patients over 18 years of age;
• Patient has proven informed consent;
• Subject with indication of dual chamber pacemaker due to Sinus Node Dysfunction;
• Subjects with a dual chamber pacemaker already implanted within six months from enrollment, provided that ventricular pacing percentage ≤ 40% and with the RV lead in the apical position;
• Stable medical situation;
• Stable geographical situation;

Exclusion Criteria:

• Permanent or paroxysmal AV block ≥ II;
• Permanent AF/Afl;
• Device Replacement;
• Patient with a poor echocardiographic window;
• Patient already implanted with the RV lead not in the apical position;
• Subjects with a dual chamber pacemaker, implanted later than six months;
• Subjects with a dual chamber pacemaker with ventricular pacing percentage ≥ 40%;
• Contraindication for DDD(R)-ADI(R) or DDD(R) pacing modes;
• VpS or IRSplus algorithm contraindications;
• Age < 18 years;
• Life expectancy < 12 months;
• Cardiac surgery planned within the FU period;
• Participation to another clinical investigation;