Long Term Diabetes Improvement After Cancer Gastrectomy and Colectomy

• Fasting blood glucose [ Time Frame: 3-12 years change ] [ Designated as safety issue: No ]
  Glucose improvement or deterioration comparing preoperative versus late postoperative value. Classification according to the American Diabetes Association
  
  

• HbA1c [ Time Frame: 3-12 years ] [ Designated as safety issue: No ]
  Same as fasting blood glucose (preoperative versus current change). Classification according to the American Diabetes Association.
  
  

In a prospective protocol with retrospective information, patients (N=240) undergoing bariatric Roux-en-Y gastric bypass (n=80), cancer subtotal or total gastrectomy (n=80) and right colectomy or rectosigmoidectomy (n=80) with follow-up >3 years free of disease, with or without previously impaired fasting blood glucose, will be recruited. Patients will be submitted to a questionnaire involving diet, diagnosis of diabetes and glucose-lowering drugs, body weight and other clinical items. Preoperative information available in the hospital system will be completed and current findings will be updated, including body mass index and biochemical measurements. Using the outcomes of the bariatric population as benchmark, both concerning diabetics that were ameliorated and nondiabetics that progressed to new-onset diabetes,results in the other groups will be compared. The study should answer whether gastric and colorectal surgery for cancer 1) Are beneficial for established diabetes; 2) Attenuate the conversion of normal patients to diabetes, both within a follow-up period of 3- 12 years;