Trial record 1 of 1 for:    SWOG S1201
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S1201: Combination Chemo for Patients W/Advanced or Metastatic Esophageal, Gastric, or Gastroesophageal Junction Cancer

This study is currently recruiting participants.
Verified January 2014 by Southwest Oncology Group
Sponsor:
Collaborator:
Information provided by (Responsible Party):
Southwest Oncology Group
ClinicalTrials.gov Identifier:
NCT01498289
First received: December 22, 2011
Last updated: January 13, 2014
Last verified: January 2014
  Purpose

RATIONALE: Drugs used in chemotherapy, such as oxaliplatin, leucovorin calcium, fluorouracil, irinotecan hydrochloride, and docetaxel, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Combining more than one drug may kill more tumor cells. It is not yet known which regimen of combination chemotherapy is more effective in treating tumor cells.

PURPOSE: This randomized phase II trial studies how well oxaliplatin, leucovorin calcium, and fluorouracil work compared to irinotecan hydrochloride and docetaxel in treating patients with esophageal cancer, gastric cancer, or gastroesophageal junction cancer.


Condition Intervention Phase
Adenocarcinoma of the Gastroesophageal Junction
Esophageal Cancer
Gastric Cancer
Drug: FOLFOX regimen
Drug: docetaxel
Drug: fluorouracil
Drug: irinotecan hydrochloride
Drug: leucovorin calcium
Drug: oxaliplatin
Phase 2

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Treatment
Official Title: A Randomized Phase II Pilot Study Prospectively Evaluating Treatment for Patients Based on ERCC1(Excision Repair Cross-Complementing 1) for Advanced/Metastatic Esophageal, Gastric or Gastroesophageal Junction (GEJ) Cancer

Resource links provided by NLM:


Further study details as provided by Southwest Oncology Group:

Primary Outcome Measures:
  • Progression-free survival (PFS) between high-ERCC1 and low-ERCC1 patients treated with FOLFOX versus irinotecan hydrochloride plus docetaxel [ Time Frame: Up to 3 years ] [ Designated as safety issue: No ]
  • PFS between low-ERCC1 and high-ERCC1 patients treated with FOLFOX [ Time Frame: Up to 3 years ] [ Designated as safety issue: No ]
  • PFS between low-ERCC1 and high-ERCC1 patients treated with irinotecan hydrochloride plus docetaxel [ Time Frame: Up to 3 years ] [ Designated as safety issue: No ]

Secondary Outcome Measures:
  • Overall survival [ Time Frame: Up to 3 years ] [ Designated as safety issue: No ]
  • Response rate [ Time Frame: Up to 3 years ] [ Designated as safety issue: No ]
  • Toxicity [ Time Frame: Up to 3 years ] [ Designated as safety issue: Yes ]

Estimated Enrollment: 225
Study Start Date: February 2012
Estimated Study Completion Date: March 2019
Estimated Primary Completion Date: March 2018 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: Arm I
FOLFOX regimen: Patients receive oxaliplatin IV over 2 hours and leucovorin calcium IV over 2 hours on day 1, and fluorouracil IV over 46-48 hours on days 1-2. Courses repeat every 14 days in the absence of disease progression or unacceptable toxicity.
Drug: FOLFOX regimen
Given IV. Fluorouracil, oxaliplatin, & leucovorin calcium.
Drug: fluorouracil
400 mg/m^2, IV bolus on Day 1 of each 14 day cycle; 2400 mg/m^2 IV over 46-48 hours on Days 1-2 of each 14 day cycle.
Other Names:
  • 5-fluorouracil
  • 5-FU
  • NSC-19893
Drug: leucovorin calcium
400 mg/m^2, IV over 2 hours on Day 1 of every 14 day cycle.
Other Name: NSC-3590
Drug: oxaliplatin
85 mg/m^2, IV over 2 hours on Day 1 of every 14 day cycle.
Other Names:
  • Eloxatin
  • NSC-266046
Experimental: Arm II
Patients receive irinotecan hydrochloride IV over 90 minutes and docetaxel IV over 30-60 minutes on days 1 and 8. Courses repeat every 21 days in the absence of disease progression or unacceptable toxicity.
Drug: docetaxel
30 mg/m^2, IV over 30 minutes on Day 1,8 of each 21 day cycle.
Other Names:
  • Taxotere
  • RP56976
  • NSC-628503
Drug: irinotecan hydrochloride
65 mg/m^2, IV over 90 minutes on Days 1 & 8 of every 21 day cycle.
Other Names:
  • CPT-11
  • NSC-616348

Detailed Description:

OBJECTIVES:

  • To assess progression-free survival of high-excision repair cross-complementing 1(ERCC1) patients with advanced or metastatic cancer of the esophagus, stomach, or gastroesophageal junction (GEJ) treated with FOLFOX comprising oxaliplatin, leucovorin calcium, and fluorouracil compared to those treated with irinotecan hydrochloride plus docetaxel.
  • To assess progression-free survival of low-ERCC1 patients with advanced or metastatic cancer of the esophagus, stomach, or GEJ treated with FOLFOX compared to those treated with irinotecan hydrochloride plus docetaxel.
  • To assess progression-free survival of low-ERCC1 patients with advanced or metastatic cancer of the esophagus, stomach, or GEJ treated with FOLFOX compared to high-ERCC1 patients treated with FOLFOX.
  • To assess overall survival of and toxicities in each of the two treatment arms in this group of patients.
  • To assess the response probability (confirmed and unconfirmed, complete and partial responses) in the subset of patients with measurable disease in each of the two treatment arms.
  • To explore whether there is evidence of interaction between treatment arm and ERCC1 expression in this group of patients. (Exploratory)
  • To bank tissue and blood for future translational medicine studies; a) To explore the relationship of ERCC-1 and ERCC-2 single nucleotide polymorphism (SNP) genotypes with clinical outcome in these patients; and b) To explore the association between germline variations in these SNPs and ERCC-1 mRNA expression in these patients. (Exploratory)

OUTLINE: This is a multicenter study. Patients are stratified according to ERCC1 expression (high [≥ 1.7] vs low [< 1.7]), and disease site (esophageal vs gastric/gastroesophageal junction). Patients are randomized to 1 of 2 treatment arms.

  • Arm I (FOLFOX): Patients receive oxaliplatin IV over 2 hours and leucovorin calcium IV over 2 hours on day 1, and fluorouracil IV over 46-48 hours on days 1-2. Courses repeat every 14 days in the absence of disease progression or unacceptable toxicity.
  • Arm II: Patients receive irinotecan hydrochloride IV over 90 minutes and docetaxel IV over 30-60 minutes on days 1 and 8. Courses repeat every 21 days in the absence of disease progression or unacceptable toxicity.

Blood and tumor tissue samples may be collected for ERCC1 expression analysis and future research studies.

After completion of study treatment, patients are followed up every 3 months for up to 3 years.

  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

DISEASE CHARACTERISTICS:

  • Patients must have unresectable advanced or metastatic histologically or cytologically confirmed adenocarcinoma of the esophagus, stomach, or gastroesophageal junction (GEJ)

    • Patients must not have received treatment for metastatic or unresectable disease
    • Patients must not have brain metastases
  • Patients must have measurable and/or non-measurable disease
  • Patients who have had HER-2 expression testing prior to patient consent to this study must be HER-2 negative; if HER-2 expression has not been tested prior to patient consent to this study, a second specimen must be submitted for HER-2 expression; if the specimen is HER-2 positive (or if HER-2 could not be evaluated), the patient will not be randomized
  • Patients must have completed any prior neoadjuvant and adjuvant therapy for resectable disease at least 180 days prior to registration

PATIENT CHARACTERISTICS:

  • Zubrod performance status of 0-1
  • Hemoglobin ≥ 9 g/dL
  • Absolute neutrophil count (ANC) ≥ 1,500/mcL
  • Platelets ≥ 100,000/mcL
  • Total bilirubin ≤ 1.5 mg/dL regardless of whether patients have liver involvement secondary to tumor
  • AST and ALT both ≤ 3 times institutional upper limit of normal (IULN) unless the liver is involved with tumor, in which case both AST and ALT must be ≤ 5 times IULN
  • Serum creatinine < 1.5 mg/dL within 28 days prior to registration AND/OR calculated creatinine clearance > 60 mL/min
  • Patients must not have motor or sensory neuropathy > Grade 1 using CTCAE version 4.0
  • Patients must not be pregnant or nursing; women and men of reproductive potential must have agreed to use an effective contraceptive method
  • No other prior malignancy is allowed except for the following: adequately treated basal cell or squamous cell skin cancer, in situ cervical cancer, adequately treated stage I or II cancer from which the patient is currently in complete remission, or any other cancer from which the patient has been disease-free for five years

PRIOR CONCURRENT THERAPY:

  • See Disease Characteristics
  • All palliative radiation therapy alone must be completed at least 14 days prior to registration
  • Patient must have no plans to receive concurrent chemotherapy, hormonal therapy, radiotherapy, immunotherapy, or any other type of therapy for treatment of cancer while on this protocol treatment
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT01498289

Contacts
Contact: Kimberly Kaberle 2106148808 ext 1022 kkaberle@swog.org
Contact: Dana Sparks, MAT 2106148808 ext 1004 dsparks@swog.org

  Hide Study Locations
Locations
United States, Alabama
University of South Alabama Mitchell Cancer Institute Active, not recruiting
Mobile, Alabama, United States, 36688
United States, Arkansas
University of Arkansas for Medical Sciences Recruiting
Little Rock, Arkansas, United States, 72205
Contact: Laura F. Hutchins    501-686-8274      
Principal Investigator: Laura F. Hutchins         
United States, California
Los Angeles County-USC Medical Center Recruiting
Los Angeles, California, United States, 90033
Contact: Syma Iqbal    323-865-0451      
Principal Investigator: Syma Iqbal         
University of Southern California Recruiting
Los Angeles, California, United States, 90033-0804
Contact: Syma Iqbal    323-865-0451      
Principal Investigator: Syma Iqbal         
Fremont - Rideout Cancer Center Recruiting
Marysville, California, United States, 95901
Contact: Thomas J. Semrad    916-734-3089      
Principal Investigator: Thomas J. Semrad         
University of California Medical Center At Irvine-Orange Campus Recruiting
Orange, California, United States, 92868
Contact: Chaitali S. Nangia    877-827-8839    ucstudy@uci.edu   
Principal Investigator: Chaitali S. Nangia         
Valley Medical Oncology Consultants Recruiting
Pleasanton, California, United States, 94588
Contact: Thomas J. Semrad    916-734-3089      
Principal Investigator: Thomas J. Semrad         
Sutter Roseville Medical Center Recruiting
Roseville, California, United States, 95661
Contact: Stacy D. D'Andre    916-454-6500    cancerinfo@sutterhealth.org   
Principal Investigator: Stacy D. D'Andre         
UC Davis Comprehensive Cancer Center Recruiting
Sacramento, California, United States, 95817
Contact: Thomas J. Semrad    916-734-3089      
Principal Investigator: Thomas J. Semrad         
Sutter General Hospital Recruiting
Sacramento, California, United States, 95816
Contact: Stacy D. D'Andre    916-454-6500    cancerinfo@sutterhealth.org   
Principal Investigator: Stacy D. D'Andre         
Tahoe Forest Cancer Center Recruiting
Truckee, California, United States, 96161
Contact: Thomas J. Semrad    916-734-3089      
Principal Investigator: Thomas J. Semrad         
United States, Colorado
The Medical Center of Aurora Recruiting
Aurora, Colorado, United States, 80012
Contact: Keren Sturtz    888-785-6789      
Principal Investigator: Keren Sturtz         
Boulder Community Hospital Recruiting
Boulder, Colorado, United States, 80301
Contact: Keren Sturtz    888-785-6789      
Principal Investigator: Keren Sturtz         
Penrose-Saint Francis Healthcare Recruiting
Colorado Springs, Colorado, United States, 80907
Contact: Keren Sturtz    888-785-6789      
Principal Investigator: Keren Sturtz         
Exempla Saint Joseph Hospital Recruiting
Denver, Colorado, United States, 80218
Contact: Keren Sturtz    888-785-6789      
Principal Investigator: Keren Sturtz         
Saint Anthony Central Hospital Recruiting
Denver, Colorado, United States, 80204
Contact: Keren Sturtz    888-785-6789      
Principal Investigator: Keren Sturtz         
Colorado Cancer Research Program CCOP Recruiting
Denver, Colorado, United States, 80224-2522
Contact: Keren Sturtz    888-785-6789      
Principal Investigator: Keren Sturtz         
Rose Medical Center Recruiting
Denver, Colorado, United States, 80220
Contact: Keren Sturtz    888-785-6789      
Principal Investigator: Keren Sturtz         
Porter Adventist Hospital Recruiting
Denver, Colorado, United States, 80210
Contact: Keren Sturtz    888-785-6789      
Principal Investigator: Keren Sturtz         
Presbyterian - Saint Lukes Medical Center - Health One Recruiting
Denver, Colorado, United States, 80218
Contact: Keren Sturtz    888-785-6789      
Principal Investigator: Keren Sturtz         
Swedish Medical Center Recruiting
Englewood, Colorado, United States, 80110
Contact: Keren Sturtz    888-785-6789      
Principal Investigator: Keren Sturtz         
Front Range Cancer Specialists Recruiting
Fort Collins, Colorado, United States, 80528
Contact: Diana C. Medgyesy    970-212-7600      
Principal Investigator: Diana C. Medgyesy         
Poudre Valley Hospital Recruiting
Fort Collins, Colorado, United States, 80524
Contact: Regina J. Brown    970-495-8226      
Principal Investigator: Regina J. Brown         
North Colorado Medical Center Recruiting
Greeley, Colorado, United States, 80631
Contact: Keren Sturtz    888-785-6789      
Principal Investigator: Keren Sturtz         
Littleton Adventist Hospital Recruiting
Littleton, Colorado, United States, 80122
Contact: Keren Sturtz    888-785-6789      
Principal Investigator: Keren Sturtz         
Sky Ridge Medical Center Recruiting
Lone Tree, Colorado, United States, 80124
Contact: Keren Sturtz    888-785-6789      
Principal Investigator: Keren Sturtz         
Longmont United Hospital Recruiting
Longmont, Colorado, United States, 80501
Contact: Keren Sturtz    888-785-6789      
Principal Investigator: Keren Sturtz         
McKee Medical Center Recruiting
Loveland, Colorado, United States, 80539
Contact: Keren Sturtz    888-785-6789      
Principal Investigator: Keren Sturtz         
Parker Adventist Hospital Recruiting
Parker, Colorado, United States, 80138
Contact: Keren Sturtz    888-785-6789      
Principal Investigator: Keren Sturtz         
Saint Mary Corwin Medical Center Recruiting
Pueblo, Colorado, United States, 81004
Contact: Keren Sturtz    888-785-6789      
Principal Investigator: Keren Sturtz         
Exempla Lutheran Medical Center Recruiting
Wheat Ridge, Colorado, United States, 80033
Contact: Keren Sturtz    888-785-6789      
Principal Investigator: Keren Sturtz         
United States, Connecticut
Saint Francis Hospital and Medical Center Recruiting
Hartford, Connecticut, United States, 06105
Contact: Christopher M. Reynolds    734-712-3456      
Principal Investigator: Christopher M. Reynolds         
United States, Delaware
Beebe Medical Center Recruiting
Lewes, Delaware, United States, 19958
Contact: Stephen S. Grubbs    302-733-6227      
Principal Investigator: Stephen S. Grubbs         
Christiana Care Health System-Christiana Hospital Recruiting
Newark, Delaware, United States, 19718
Contact: Stephen S. Grubbs    302-733-6227      
Principal Investigator: Stephen S. Grubbs         
United States, Florida
Broward Health Medical Center Recruiting
Fort Lauderdale, Florida, United States, 33316
Contact: Archana Maini    954-355-5346      
Principal Investigator: Archana Maini         
Holy Cross Hospital Recruiting
Fort Lauderdale, Florida, United States, 33308
Contact: Mike Cusnir    305-674-2625    info@msccop.com   
Principal Investigator: Mike Cusnir         
Jupiter Medical Center Recruiting
Jupiter, Florida, United States, 33458
Contact: Mike Cusnir    305-674-2625    info@msccop.com   
Principal Investigator: Mike Cusnir         
Mount Sinai Medical Center CCOP Recruiting
Miami Beach, Florida, United States, 33140
Contact: Mike Cusnir    305-674-2625    info@msccop.com   
Principal Investigator: Mike Cusnir         
Florida Hospital Recruiting
Orlando, Florida, United States, 32803
Contact: Lee M. Zehngebot    407-303-5623      
Principal Investigator: Lee M. Zehngebot         
United States, Georgia
Phoebe Putney Memorial Hospital Recruiting
Albany, Georgia, United States, 31701
Contact: Robert F. Krywicki    229-312-2251      
Principal Investigator: Robert F. Krywicki         
John B Amos Cancer Center Recruiting
Columbus, Georgia, United States, 31904
Contact: Andrew W. Pippas    706-660-6404      
Principal Investigator: Andrew W. Pippas         
Memorial Health University Medical Center Recruiting
Savannah, Georgia, United States, 31403
Contact: Harvey C. Lebos    912-350-8568      
Principal Investigator: Harvey C. Lebos         
United States, Hawaii
Oncare Hawaii Inc - Kapiolani Medical Center at Pali Momi Recruiting
Aiea, Hawaii, United States, 96701
Contact: Jeffrey L. Berenberg    808-586-2979      
Principal Investigator: Jeffrey L. Berenberg         
Kapiolani Medical Center at Pali Momi Recruiting
Aiea, Hawaii, United States, 96701
Contact: Jeffrey L. Berenberg    808-586-2979      
Principal Investigator: Jeffrey L. Berenberg         
Kapiolani Medical Center for Women and Children Recruiting
Honolulu, Hawaii, United States, 96826
Contact: Jeffrey L. Berenberg    808-586-2979      
Principal Investigator: Jeffrey L. Berenberg         
Kuakini Medical Center Recruiting
Honolulu, Hawaii, United States, 96817
Contact: Jeffrey L. Berenberg    808-586-2979      
Principal Investigator: Jeffrey L. Berenberg         
OnCare Hawaii-Liliha Recruiting
Honolulu, Hawaii, United States, 96817-3169
Contact: Jeffrey L. Berenberg    808-586-2979      
Principal Investigator: Jeffrey L. Berenberg         
Oncare Hawaii Inc-POB II Recruiting
Honolulu, Hawaii, United States, 96813
Contact: Jeffrey L. Berenberg    808-586-2979      
Principal Investigator: Jeffrey L. Berenberg         
Oncare Hawaii Inc-Kuakini Recruiting
Honolulu, Hawaii, United States, 96817
Contact: Jeffrey L. Berenberg    808-586-2979      
Principal Investigator: Jeffrey L. Berenberg         
Queen's Medical Center Recruiting
Honolulu, Hawaii, United States, 96813
Contact: Jeffrey L. Berenberg    808-586-2979      
Principal Investigator: Jeffrey L. Berenberg         
Straub Clinic and Hospital Recruiting
Honolulu, Hawaii, United States, 96813
Contact: Jeffrey L. Berenberg    808-586-2979      
Principal Investigator: Jeffrey L. Berenberg         
University of Hawaii Recruiting
Honolulu, Hawaii, United States, 96813
Contact: Jeffrey L. Berenberg    808-586-2979      
Principal Investigator: Jeffrey L. Berenberg         
Castle Medical Center Recruiting
Kailua, Hawaii, United States, 96734
Contact: Jeffrey L. Berenberg    808-586-2979      
Principal Investigator: Jeffrey L. Berenberg         
Wilcox Memorial Hospital and Kauai Medical Clinic Recruiting
Lihue, Hawaii, United States, 96766
Contact: Jeffrey L. Berenberg    808-586-2979      
Principal Investigator: Jeffrey L. Berenberg         
United States, Idaho
Saint Alphonsus Regional Medical Center Recruiting
Boise, Idaho, United States, 83706
Contact: Christopher M. Reynolds    734-712-3456      
Principal Investigator: Christopher M. Reynolds         
Saint Joseph Regional Medical Center Recruiting
Lewiston, Idaho, United States, 83501
Contact: Yoshio Inoue    253-403-2394      
Principal Investigator: Yoshio Inoue         
Idaho Urologic Institute PA Active, not recruiting
Meridian, Idaho, United States, 83642
Kootenai Cancer Center Recruiting
Post Falls, Idaho, United States, 83854
Contact: Benjamin T. Marchello    800-648-6274      
Principal Investigator: Benjamin T. Marchello         
United States, Illinois
Saint Anthony's Health Active, not recruiting
Alton, Illinois, United States, 62002
Saint Joseph Medical Center Recruiting
Bloomington, Illinois, United States, 61701
Contact: Nguyet A. Le-Lindqwister    800-793-2262      
Principal Investigator: Nguyet A. Le-Lindqwister         
Illinois CancerCare-Bloomington Recruiting
Bloomington, Illinois, United States, 61701
Contact: Nguyet A. Le-Lindqwister    800-793-2262      
Principal Investigator: Nguyet A. Le-Lindqwister         
Illinois CancerCare-Canton Recruiting
Canton, Illinois, United States, 61520
Contact: Nguyet A. Le-Lindqwister    800-793-2262      
Principal Investigator: Nguyet A. Le-Lindqwister         
Graham Hospital Association Active, not recruiting
Canton, Illinois, United States, 61520
Illinois CancerCare-Carthage Recruiting
Carthage, Illinois, United States, 62321
Contact: Nguyet A. Le-Lindqwister    800-793-2262      
Principal Investigator: Nguyet A. Le-Lindqwister         
Memorial Hospital Active, not recruiting
Carthage, Illinois, United States, 62321
Northwestern University Recruiting
Chicago, Illinois, United States, 60611
Contact: Al B. Benson    312-695-1301    cancer@northwestern.edu   
Principal Investigator: Al B. Benson         
University of Illinois Recruiting
Chicago, Illinois, United States, 60612
Contact: Neeta K. Venepalli    312-355-3046      
Principal Investigator: Neeta K. Venepalli         
Hematology and Oncology Associates Terminated
Chicago, Illinois, United States, 60611
Decatur Memorial Hospital Recruiting
Decatur, Illinois, United States, 62526
Contact: James L. Wade    217-876-4740    kcheek@dmhhs.org   
Principal Investigator: James L. Wade         
Eureka Hospital Active, not recruiting
Eureka, Illinois, United States, 61530
Illinois CancerCare-Eureka Recruiting
Eureka, Illinois, United States, 61530
Contact: Nguyet A. Le-Lindqwister    800-793-2262      
Principal Investigator: Nguyet A. Le-Lindqwister         
Medical and Surgical Specialists Recruiting
Galesburg, Illinois, United States, 61401
Contact: Nguyet A. Le-Lindqwister    800-793-2262      
Principal Investigator: Nguyet A. Le-Lindqwister         
Illinois CancerCare Galesburg Recruiting
Galesburg, Illinois, United States, 61401
Contact: Nguyet A. Le-Lindqwister    800-793-2262      
Principal Investigator: Nguyet A. Le-Lindqwister         
Illinois CancerCare-Havana Active, not recruiting
Havana, Illinois, United States, 62644
Mason District Hospital Active, not recruiting
Havana, Illinois, United States, 62644
Hematology Oncology Associates of Illinois-Highland Park Recruiting
Highland Park, Illinois, United States, 60035
Contact: Al B. Benson    312-695-1301    cancer@northwestern.edu   
Principal Investigator: Al B. Benson         
Presence Saint Mary's Hospital Recruiting
Kankakee, Illinois, United States, 60901
Contact: Al B. Benson    312-695-1301    cancer@northwestern.edu   
Principal Investigator: Al B. Benson         
Illinois CancerCare-Kewanee Clinic Recruiting
Kewanee, Illinois, United States, 61443
Contact: Nguyet A. Le-Lindqwister    800-793-2262      
Principal Investigator: Nguyet A. Le-Lindqwister         
Adventist La Grange Memorial Hospital Recruiting
La Grange, Illinois, United States, 60525
Contact: Renee H. Jacobs    630-856-7526      
Principal Investigator: Renee H. Jacobs         
North Shore Hematology Oncology Recruiting
Libertyville, Illinois, United States, 60048
Contact: Al B. Benson    312-695-1301    cancer@northwestern.edu   
Principal Investigator: Al B. Benson         
Illinois CancerCare-Macomb Recruiting
Macomb, Illinois, United States, 61455
Contact: Nguyet A. Le-Lindqwister    800-793-2262      
Principal Investigator: Nguyet A. Le-Lindqwister         
Mcdonough District Hospital Active, not recruiting
Macomb, Illinois, United States, 61455
Loyola University Medical Center Recruiting
Maywood, Illinois, United States, 60153
Contact: Janelle M. Meyer    708-226-4357      
Principal Investigator: Janelle M. Meyer         
Garneau, Stewart C MD (UIA Investigator) Recruiting
Moline, Illinois, United States, 61265
Contact: Costas L. Constantinou    319-363-2690      
Principal Investigator: Costas L. Constantinou         
Trinity Medical Center Recruiting
Moline, Illinois, United States, 61265
Contact: Costas L. Constantinou    319-363-2690      
Principal Investigator: Costas L. Constantinou         
Spector, David MD (UIA Investigator) Recruiting
Moline, Illinois, United States, 61265
Contact: Costas L. Constantinou    319-363-2690      
Principal Investigator: Costas L. Constantinou         
Porubcin, Michael MD (UIA Investigator) Recruiting
Moline, Illinois, United States, 61265
Contact: Costas L. Constantinou    319-363-2690      
Principal Investigator: Costas L. Constantinou         
Illinois CancerCare-Monmouth Recruiting
Monmouth, Illinois, United States, 61462
Contact: Nguyet A. Le-Lindqwister    800-793-2262      
Principal Investigator: Nguyet A. Le-Lindqwister         
Holy Family Medical Center Terminated
Monmouth, Illinois, United States, 61462
Good Samaritan Regional Medical Center Recruiting
Mt. Vernon, Illinois, United States, 62864
Contact: Robert L. Carolla    417-269-4520      
Principal Investigator: Robert L. Carolla         
Hematology Oncology Consultants Limited Recruiting
Naperville, Illinois, United States, 60540
Contact: Fariborze B. Barhamand    630-369-1501      
Principal Investigator: Fariborze B. Barhamand         
Illinois Cancer Specialists-Niles Recruiting
Niles, Illinois, United States, 60714
Contact: Al B. Benson    312-695-1301    cancer@northwestern.edu   
Principal Investigator: Al B. Benson         
Illinois CancerCare-Community Cancer Center Active, not recruiting
Normal, Illinois, United States, 61761
Community Cancer Center Foundation Recruiting
Normal, Illinois, United States, 61761
Contact: Nguyet A. Le-Lindqwister    800-793-2262      
Principal Investigator: Nguyet A. Le-Lindqwister         
Bromenn Regional Medical Center Active, not recruiting
Normal, Illinois, United States, 61761
Illinois CancerCare-Ottawa Clinic Recruiting
Ottawa, Illinois, United States, 61350
Contact: Nguyet A. Le-Lindqwister    800-793-2262      
Principal Investigator: Nguyet A. Le-Lindqwister         
Ottawa Regional Hospital and Healthcare Center Recruiting
Ottawa, Illinois, United States, 61350
Contact: Nguyet A. Le-Lindqwister    800-793-2262      
Principal Investigator: Nguyet A. Le-Lindqwister         
Pekin Cancer Treatment Center Recruiting
Pekin, Illinois, United States, 61554
Contact: Nguyet A. Le-Lindqwister    800-793-2262      
Principal Investigator: Nguyet A. Le-Lindqwister         
Illinois CancerCare-Pekin Recruiting
Pekin, Illinois, United States, 61603
Contact: Nguyet A. Le-Lindqwister    800-793-2262      
Principal Investigator: Nguyet A. Le-Lindqwister         
OSF Saint Francis Medical Center Recruiting
Peoria, Illinois, United States, 61637
Contact: Nguyet A. Le-Lindqwister    800-793-2262      
Principal Investigator: Nguyet A. Le-Lindqwister         
Illinois CancerCare-Peoria Recruiting
Peoria, Illinois, United States, 61615
Contact: Nguyet A. Le-Lindqwister    800-793-2262      
Principal Investigator: Nguyet A. Le-Lindqwister         
Illinois Oncology Research Association CCOP Recruiting
Peoria, Illinois, United States, 61615
Contact: Nguyet A. Le-Lindqwister    800-793-2262      
Principal Investigator: Nguyet A. Le-Lindqwister         
Methodist Medical Center of Illinois Recruiting
Peoria, Illinois, United States, 61603
Contact: Nguyet A. Le-Lindqwister    800-793-2262      
Principal Investigator: Nguyet A. Le-Lindqwister         
Proctor Hospital Recruiting
Peoria, Illinois, United States, 61614
Contact: Nguyet A. Le-Lindqwister    800-793-2262      
Principal Investigator: Nguyet A. Le-Lindqwister         
Illinois CancerCare-Peru Recruiting
Peru, Illinois, United States, 61354
Contact: Nguyet A. Le-Lindqwister    800-793-2262      
Principal Investigator: Nguyet A. Le-Lindqwister         
Illinois Valley Hospital Active, not recruiting
Peru, Illinois, United States, 61354
Perry Memorial Hospital Active, not recruiting
Princeton, Illinois, United States, 61356
Illinois CancerCare-Princeton Recruiting
Princeton, Illinois, United States, 61356
Contact: Nguyet A. Le-Lindqwister    800-793-2262      
Principal Investigator: Nguyet A. Le-Lindqwister         
SwedishAmerican Regional Cancer Center/ACT Recruiting
Rockford, Illinois, United States, 61107
Contact: Harvey E. Einhorn    779-696-9400    cancercare@swedishamerican.org   
Principal Investigator: Harvey E. Einhorn         
Swedish American Hospital Withdrawn
Rockford, Illinois, United States, 61104
Hematology Oncology Associates of Illinois - Skokie Recruiting
Skokie, Illinois, United States, 60076
Contact: Al B. Benson    312-695-1301    cancer@northwestern.edu   
Principal Investigator: Al B. Benson         
Illinois CancerCare-Spring Valley Active, not recruiting
Spring Valley, Illinois, United States, 61362
Memorial Medical Center Recruiting
Springfield, Illinois, United States, 62781-0001
Contact: James L. Wade    217-876-4740    kcheek@dmhhs.org   
Principal Investigator: James L. Wade         
United States, Indiana
Saint Francis Hospital and Health Centers Recruiting
Beech Grove, Indiana, United States, 46107
Contact: Howard M. Gross    765-983-3000      
Principal Investigator: Howard M. Gross         
Elkhart Clinic Recruiting
Elkhart, Indiana, United States, 46514-2098
Contact: Robin T. Zon    574-234-5123      
Principal Investigator: Robin T. Zon         
Elkhart General Hospital Recruiting
Elkhart, Indiana, United States, 46515
Contact: Robin T. Zon    574-234-5123      
Principal Investigator: Robin T. Zon         
Michiana Hematology Oncology PC-Elkhart Recruiting
Elkhart, Indiana, United States, 46514
Contact: Robin T. Zon    574-234-5123      
Principal Investigator: Robin T. Zon         
Fort Wayne Medical Oncology and Hematology Inc - State Boulevard Recruiting
Fort Wayne, Indiana, United States, 46845
Contact: Sreenivasa R. Nattam    260-484-8830    ledgar@fwmoh.com   
Principal Investigator: Sreenivasa R. Nattam         
Franciscan St. Francis Health Recruiting
Indianapolis, Indiana, United States, 46237
Contact: Howard M. Gross    765-983-3000      
Principal Investigator: Howard M. Gross         
Community Howard Regional Health Recruiting
Kokomo, Indiana, United States, 46904
Contact: Robin T. Zon    574-234-5123      
Principal Investigator: Robin T. Zon         
Indiana University Health La Porte Hospital Recruiting
La Porte, Indiana, United States, 46350
Contact: Robin T. Zon    574-234-5123      
Principal Investigator: Robin T. Zon         
Cancer Care Partners LLC Recruiting
Mishawaka, Indiana, United States, 46545
Contact: Robin T. Zon    574-234-5123      
Principal Investigator: Robin T. Zon         
Michiana Hematology Oncology PC-Mishawaka Recruiting
Mishawaka, Indiana, United States, 46545-1470
Contact: Robin T. Zon    574-234-5123      
Principal Investigator: Robin T. Zon         
Saint Joseph Regional Medical Center-Mishawaka Recruiting
Mishawaka, Indiana, United States, 46545-1470
Contact: Robin T. Zon    574-234-5123      
Principal Investigator: Robin T. Zon         
Michiana Hematology Oncology PC-Plymouth Recruiting
Plymouth, Indiana, United States, 46563
Contact: Robin T. Zon    574-234-5123      
Principal Investigator: Robin T. Zon         
Reid Hospital and Health Care Services Recruiting
Richmond, Indiana, United States, 47374
Contact: Howard M. Gross    317-783-8918      
Principal Investigator: Howard M. Gross         
Memorial Hospital of South Bend Recruiting
South Bend, Indiana, United States, 46601
Contact: Robin T. Zon    574-234-5123      
Principal Investigator: Robin T. Zon         
Michiana Hematology Oncology PC-South Bend Recruiting
South Bend, Indiana, United States, 46601
Contact: Robin T. Zon    574-234-5123      
Principal Investigator: Robin T. Zon         
Northern Indiana Cancer Research Consortium Recruiting
South Bend, Indiana, United States, 46628
Contact: Robin T. Zon    574-234-5123      
Principal Investigator: Robin T. Zon         
South Bend Clinic Recruiting
South Bend, Indiana, United States, 46617
Contact: Robin T. Zon    574-234-5123      
Principal Investigator: Robin T. Zon         
Michiana Hematology Oncology-PC Westville Recruiting
Westville, Indiana, United States, 46391
Contact: Robin T. Zon    574-234-5123      
Principal Investigator: Robin T. Zon         
United States, Iowa
McFarland Clinic Recruiting
Ames, Iowa, United States, 50010
Contact: Joseph J. Merchant    515-239-2621      
Principal Investigator: Joseph J. Merchant         
Constantinou, Costas L MD (UIA Investigator) Recruiting
Bettendorf, Iowa, United States, 52722
Contact: Costas L. Constantinou    319-363-2690      
Principal Investigator: Costas L. Constantinou         
Genesis Medical Center - East Campus Recruiting
Davenport, Iowa, United States, 52803
Contact: George Kovach    800-446-6088    werners@genesishealth.com   
Principal Investigator: George Kovach         
Mercy Medical Center-Sioux City Recruiting
Sioux City, Iowa, United States, 51104
Contact: Donald B. Wender    712-252-0088      
Principal Investigator: Donald B. Wender         
Saint Luke's Regional Medical Center Recruiting
Sioux City, Iowa, United States, 51104
Contact: Donald B. Wender    712-252-0088      
Principal Investigator: Donald B. Wender         
Siouxland Hematology Oncology Associates Recruiting
Sioux City, Iowa, United States, 51101
Contact: Donald B. Wender    712-252-0088      
Principal Investigator: Donald B. Wender         
Covenant Medical Center Recruiting
Waterloo, Iowa, United States, 50702
Contact: Mohammed T. Masri    319-272-2070      
Principal Investigator: Mohammed T. Masri         
United States, Kansas
Cancer Center of Kansas - Chanute Recruiting
Chanute, Kansas, United States, 66720
Contact: Shaker R. Dakhil    316-262-4467      
Principal Investigator: Shaker R. Dakhil         
Cancer Center of Kansas - Dodge City Recruiting
Dodge City, Kansas, United States, 67801
Contact: Shaker R. Dakhil    316-262-4467      
Principal Investigator: Shaker R. Dakhil         
Cancer Center of Kansas - El Dorado Recruiting
El Dorado, Kansas, United States, 67042
Contact: Shaker R. Dakhil    316-262-4467      
Principal Investigator: Shaker R. Dakhil         
Cancer Center of Kansas - Fort Scott Recruiting
Fort Scott, Kansas, United States, 66701
Contact: Shaker R. Dakhil    316-262-4467      
Principal Investigator: Shaker R. Dakhil         
Saint Rose Ambulatory and Surgery Center Recruiting
Great Bend, Kansas, United States, 67530
Contact: Peter J. Van Veldhuizen    800-525-1483      
Principal Investigator: Peter J. Van Veldhuizen         
Hays Medical Center Recruiting
Hays, Kansas, United States, 67601
Contact: Peter J. Van Veldhuizen    800-525-1483      
Principal Investigator: Peter J. Van Veldhuizen         
Promise Regional Medical Center-Hutchinson Terminated
Hutchinson, Kansas, United States, 65702
Cancer Center of Kansas-Independence Recruiting
Independence, Kansas, United States, 67301
Contact: Shaker R. Dakhil    316-262-4467      
Principal Investigator: Shaker R. Dakhil         
Kansas City Cancer Center-West Recruiting
Kansas City, Kansas, United States, 66112
Contact: Peter J. Van Veldhuizen    800-525-1483      
Principal Investigator: Peter J. Van Veldhuizen         
Providence Medical Center Recruiting
Kansas City, Kansas, United States, 66112
Contact: Rakesh Gaur    913-948-5588    amy.krushelniski@hcahealthcare.com   
Principal Investigator: Rakesh Gaur         
University of Kansas Medical Center Recruiting
Kansas City, Kansas, United States, 66160
Contact: Peter J. Van Veldhuizen    800-525-1483      
Principal Investigator: Peter J. Van Veldhuizen         
Cancer Center of Kansas-Kingman Recruiting
Kingman, Kansas, United States, 67068
Contact: Shaker R. Dakhil    316-262-4467      
Principal Investigator: Shaker R. Dakhil         
Lawrence Memorial Hospital Recruiting
Lawrence, Kansas, United States, 66044
Contact: Shaker R. Dakhil    316-262-4467      
Principal Investigator: Shaker R. Dakhil         
Cancer Center of Kansas-Liberal Recruiting
Liberal, Kansas, United States, 67901
Contact: Shaker R. Dakhil    316-262-4467      
Principal Investigator: Shaker R. Dakhil         
Cancer Center of Kansas - McPherson Recruiting
McPherson, Kansas, United States, 67460
Contact: Shaker R. Dakhil    316-262-4467      
Principal Investigator: Shaker R. Dakhil         
Cancer Center of Kansas - Newton Recruiting
Newton, Kansas, United States, 67114
Contact: Shaker R. Dakhil    316-262-4467      
Principal Investigator: Shaker R. Dakhil         
Menorah Medical Center Recruiting
Overland Park, Kansas, United States, 66209
Contact: Rakesh Gaur    913-948-5588    amy.krushelniski@hcahealthcare.com   
Principal Investigator: Rakesh Gaur         
Saint Luke's South Hospital Recruiting
Overland Park, Kansas, United States, 66213
Contact: Rakesh Gaur    913-948-5588    amy.krushelniski@hcahealthcare.com   
Principal Investigator: Rakesh Gaur         
Kansas City Cancer Centers-Southwest Recruiting
Overland Park, Kansas, United States, 66210
Contact: Peter J. Van Veldhuizen    800-525-1483      
Principal Investigator: Peter J. Van Veldhuizen         
Cancer Center of Kansas - Parsons Recruiting
Parsons, Kansas, United States, 67357
Contact: Shaker R. Dakhil    316-262-4467      
Principal Investigator: Shaker R. Dakhil         
Via Christi Hospital-Pittsburg Recruiting
Pittsburg, Kansas, United States, 66762
Contact: Peter J. Van Veldhuizen    800-525-1483      
Principal Investigator: Peter J. Van Veldhuizen         
Kansas City CCOP Recruiting
Prairie Village, Kansas, United States, 66208
Contact: Rakesh Gaur    913-948-5588    amy.krushelniski@hcahealthcare.com   
Principal Investigator: Rakesh Gaur         
Cancer Center of Kansas - Pratt Recruiting
Pratt, Kansas, United States, 67124
Contact: Shaker R. Dakhil    316-262-4467      
Principal Investigator: Shaker R. Dakhil         
Cancer Center of Kansas - Salina Recruiting
Salina, Kansas, United States, 67401
Contact: Shaker R. Dakhil    316-262-4467      
Principal Investigator: Shaker R. Dakhil         
Salina Regional Health Center Recruiting
Salina, Kansas, United States, 67401
Contact: Peter J. Van Veldhuizen    800-525-1483      
Principal Investigator: Peter J. Van Veldhuizen         
Kansas City Cancer Center-Shawnee Mission Terminated
Shawnee Mission, Kansas, United States, 66204
Saint Francis Hospital and Medical Center - Topeka Recruiting
Topeka, Kansas, United States, 66606
Contact: Peter J. Van Veldhuizen    800-525-1483      
Principal Investigator: Peter J. Van Veldhuizen         
Cancer Center of Kansas - Wellington Recruiting
Wellington, Kansas, United States, 67152
Contact: Shaker R. Dakhil    316-262-4467      
Principal Investigator: Shaker R. Dakhil         
Cancer Center of Kansas - Main Office Recruiting
Wichita, Kansas, United States, 67214
Contact: Shaker R. Dakhil    316-262-4467      
Principal Investigator: Shaker R. Dakhil         
Associates In Womens Health Recruiting
Wichita, Kansas, United States, 67208
Contact: Shaker R. Dakhil    316-262-4467      
Principal Investigator: Shaker R. Dakhil         
Cancer Center of Kansas-Wichita Medical Arts Tower Recruiting
Wichita, Kansas, United States, 67208
Contact: Shaker R. Dakhil    316-262-4467      
Principal Investigator: Shaker R. Dakhil         
Via Christi Regional Medical Center Recruiting
Wichita, Kansas, United States, 67214
Contact: Shaker R. Dakhil    316-262-4467      
Principal Investigator: Shaker R. Dakhil         
Wichita CCOP Recruiting
Wichita, Kansas, United States, 67214
Contact: Shaker R. Dakhil    316-262-4467      
Principal Investigator: Shaker R. Dakhil         
Cancer Center of Kansas - Winfield Recruiting
Winfield, Kansas, United States, 67156
Contact: Shaker R. Dakhil    316-262-4467      
Principal Investigator: Shaker R. Dakhil         
United States, Louisiana
Ochsner Clinic Foundation-Baton Rouge Recruiting
Baton Rouge, Louisiana, United States, 70809
Contact: Jyotsna Fuloria    888-562-4763      
Principal Investigator: Jyotsna Fuloria         
Ochsner Baptist Medical Center Recruiting
New Orleans, Louisiana, United States, 70115
Contact: Jyotsna Fuloria    888-562-4763      
Principal Investigator: Jyotsna Fuloria         
Ochsner Clinic Foundation Recruiting
New Orleans, Louisiana, United States, 70121
Contact: Jyotsna Fuloria    888-562-4763      
Principal Investigator: Jyotsna Fuloria         
Louisiana State University Recruiting
Shreveport, Louisiana, United States, 71130
Contact: Gary V. Burton    318-813-1412      
Principal Investigator: Gary V. Burton         
United States, Maine
Harold Alfond Center for Cancer Care Recruiting
Augusta, Maine, United States, 04330
Contact: Thomas H. Openshaw    207-973-4274      
Principal Investigator: Thomas H. Openshaw         
Eastern Maine Medical Center Recruiting
Bangor, Maine, United States, 04401
Contact: Thomas H. Openshaw    207-973-4274      
Principal Investigator: Thomas H. Openshaw         
United States, Maryland
Union Hospital of Cecil County Recruiting
Elkton MD, Maryland, United States, 21921
Contact: Stephen S. Grubbs    302-733-6227      
Principal Investigator: Stephen S. Grubbs         
Frederick Memorial Hospital Recruiting
Frederick, Maryland, United States, 21701
Contact: Mark G. Goldstein    240-566-3584    clinicaltrials@fmh.org   
Principal Investigator: Mark G. Goldstein         
United States, Michigan
Hickman Cancer Center Recruiting
Adrian, Michigan, United States, 49221
Contact: Rex B. Mowat    517-265-0116      
Principal Investigator: Rex B. Mowat         
Bixby Medical Center Recruiting
Adrian, Michigan, United States, 49221
Contact: Rex B. Mowat    517-265-0116      
Principal Investigator: Rex B. Mowat         
Saint Joseph Mercy Hospital Recruiting
Ann Arbor, Michigan, United States, 48106-0995
Contact: Christopher M. Reynolds    734-712-3456      
Principal Investigator: Christopher M. Reynolds         
University of Michigan Recruiting
Ann Arbor, Michigan, United States, 48109
Contact: Mark M. Zalupski    800-865-1125      
Principal Investigator: Mark M. Zalupski         
Veteran's Administration Medical Center - Ann Arbor Active, not recruiting
Ann Arbor, Michigan, United States, 48105
Michigan Cancer Research Consortium Community Clinical Oncology Program Recruiting
Ann Arbor, Michigan, United States, 48106
Contact: Christopher M. Reynolds    734-712-3456      
Principal Investigator: Christopher M. Reynolds         
Bronson Battle Creek Recruiting
Battle Creek, Michigan, United States, 49017
Contact: Gilbert D. Padula    616-685-5225      
Principal Investigator: Gilbert D. Padula         
Mecosta County Medical Center Recruiting
Big Rapids, Michigan, United States, 49307
Contact: Gilbert D. Padula    616-685-5225      
Principal Investigator: Gilbert D. Padula         
Oakwood Hospital Recruiting
Dearborn, Michigan, United States, 48124
Contact: Christopher M. Reynolds    734-712-3456      
Principal Investigator: Christopher M. Reynolds         
Saint John Hospital and Medical Center Recruiting
Detroit, Michigan, United States, 48236
Contact: Christopher M. Reynolds    734-712-3456      
Principal Investigator: Christopher M. Reynolds         
Wayne State University Recruiting
Detroit, Michigan, United States, 48202
Contact: Minsig Choi    313-576-9363      
Principal Investigator: Minsig Choi         
Henry Ford Hospital Recruiting
Detroit, Michigan, United States, 48202
Contact: Robert A. Chapman    313-916-1784      
Principal Investigator: Robert A. Chapman         
Green Bay Oncology - Escanaba Recruiting
Escanaba, Michigan, United States, 49431
Contact: Matthew L. Ryan    800-432-6049      
Principal Investigator: Matthew L. Ryan         
Genesys Hurley Cancer Institute Recruiting
Flint, Michigan, United States, 48503
Contact: Christopher M. Reynolds    734-712-3456      
Principal Investigator: Christopher M. Reynolds         
Hurley Medical Center Recruiting
Flint, Michigan, United States, 48502
Contact: Christopher M. Reynolds    734-712-3456      
Principal Investigator: Christopher M. Reynolds         
Genesys Regional Medical Center-West Flint Campus Recruiting
Flint, Michigan, United States, 48532
Contact: Christopher M. Reynolds    734-712-3456      
Principal Investigator: Christopher M. Reynolds         
Genesys Regional Medical Center Active, not recruiting
Grand Blanc, Michigan, United States, 48439
Spectrum Health at Butterworth Campus Recruiting
Grand Rapids, Michigan, United States, 49503
Contact: Gilbert D. Padula    616-685-5225      
Principal Investigator: Gilbert D. Padula         
Saint Mary's Health Care Recruiting
Grand Rapids, Michigan, United States, 49503
Contact: Gilbert D. Padula    616-685-5225      
Principal Investigator: Gilbert D. Padula         
Grand Rapids Clinical Oncology Program Recruiting
Grand Rapids, Michigan, United States, 49503
Contact: Gilbert D. Padula    616-685-5225      
Principal Investigator: Gilbert D. Padula         
Green Bay Oncology - Iron Mountain Recruiting
Iron Mountain, Michigan, United States, 49801
Contact: Matthew L. Ryan    800-432-6049      
Principal Investigator: Matthew L. Ryan         
Allegiance Health Recruiting
Jackson, Michigan, United States, 49201
Contact: Christopher M. Reynolds    734-712-3456      
Principal Investigator: Christopher M. Reynolds         
West Michigan Cancer Center Recruiting
Kalamazoo, Michigan, United States, 49007
Contact: Raymond S. Lord    269-373-7458      
Principal Investigator: Raymond S. Lord         
Bronson Methodist Hospital Recruiting
Kalamazoo, Michigan, United States, 49007
Contact: Raymond S. Lord    269-373-7458      
Principal Investigator: Raymond S. Lord         
Borgess Medical Center Recruiting
Kalamazoo, Michigan, United States, 49001
Contact: Raymond S. Lord    269-373-7458      
Principal Investigator: Raymond S. Lord         
Sparrow Hospital Recruiting
Lansing, Michigan, United States, 48912
Contact: Christopher M. Reynolds    734-712-3456      
Principal Investigator: Christopher M. Reynolds         
Saint Mary Mercy Hospital Recruiting
Livonia, Michigan, United States, 48154
Contact: Christopher M. Reynolds    734-712-3456      
Principal Investigator: Christopher M. Reynolds         
Community Cancer Center of Monroe Recruiting
Monroe, Michigan, United States, 48162
Contact: Rex B. Mowat    517-265-0116      
Principal Investigator: Rex B. Mowat         
Mercy Memorial Hospital Recruiting
Monroe, Michigan, United States, 48162
Contact: Rex B. Mowat    517-265-0116      
Principal Investigator: Rex B. Mowat         
Mercy Health Partners-Mercy Campus Recruiting
Muskegon, Michigan, United States, 49444
Contact: Gilbert D. Padula    616-685-5225      
Principal Investigator: Gilbert D. Padula         
Saint Joseph Mercy Oakland Recruiting
Pontiac, Michigan, United States, 48341-2985
Contact: Christopher M. Reynolds    734-712-3456      
Principal Investigator: Christopher M. Reynolds         
Saint Joseph Mercy Port Huron Recruiting
Port Huron, Michigan, United States, 48060
Contact: Christopher M. Reynolds    734-712-3456      
Principal Investigator: Christopher M. Reynolds         
Spectrum Health Reed City Hospital Recruiting
Reed City, Michigan, United States, 49677
Contact: Gilbert D. Padula    616-685-5225      
Principal Investigator: Gilbert D. Padula         
Saint Mary's of Michigan Recruiting
Saginaw, Michigan, United States, 48601
Contact: Christopher M. Reynolds    734-712-3456      
Principal Investigator: Christopher M. Reynolds         
Marie Yeager Cancer Center Recruiting
Saint Joseph, Michigan, United States, 49085
Contact: Robin T. Zon    574-234-5123      
Principal Investigator: Robin T. Zon         
Lakeland Hospital Recruiting
St. Joseph, Michigan, United States, 49085
Contact: Robin T. Zon    574-234-5123      
Principal Investigator: Robin T. Zon         
Munson Medical Center Recruiting
Traverse City, Michigan, United States, 49684
Contact: Gilbert D. Padula    616-685-5225      
Principal Investigator: Gilbert D. Padula         
Saint John Macomb-Oakland Hospital Recruiting
Warren, Michigan, United States, 48093
Contact: Christopher M. Reynolds    734-712-3456      
Principal Investigator: Christopher M. Reynolds         
United States, Minnesota
Sanford Clinic North-Bemidgi Recruiting
Bemidji, Minnesota, United States, 56601
Contact: Preston D. Steen    701-234-6161      
Principal Investigator: Preston D. Steen         
United States, Mississippi
University of Mississippi Medical Center Recruiting
Jackson, Mississippi, United States, 39216
Contact: Louis V. Puneky    601-815-6700      
Principal Investigator: Louis V. Puneky         
Singing River Hospital Recruiting
Pascagoula, Mississippi, United States, 39581
Contact: James E. Clarkson    228-809-5292      
Principal Investigator: James E. Clarkson         
United States, Missouri
Central Care Cancer Center-Carrie J Babb Cancer Center Recruiting
Bolivar, Missouri, United States, 65613
Contact: Jay W. Carlson    888-244-6061    sherrijr@iora.org   
Principal Investigator: Jay W. Carlson         
Saint Francis Medical Center Recruiting
Cape Girardeau, Missouri, United States, 63703
Contact: James L. Wade    217-876-4740    kcheek@dmhhs.org   
Principal Investigator: James L. Wade         
Southeast Cancer Center Recruiting
Cape Girardeau, Missouri, United States, 63703
Contact: Alan P. Lyss    800-392-0936      
Principal Investigator: Alan P. Lyss         
Capital Region Medical Center-Goldschmidt Cancer Center Recruiting
Jefferson City, Missouri, United States, 65109
Contact: Alan P. Lyss    800-392-0936      
Principal Investigator: Alan P. Lyss         
Freeman Health System Recruiting
Joplin, Missouri, United States, 64804
Contact: Jay W. Carlson    888-244-6061    sherrijr@iora.org   
Principal Investigator: Jay W. Carlson         
Heartland Hematology and Oncology Associates Incorporated Recruiting
Kansas City, Missouri, United States, 64118
Contact: Rakesh Gaur    913-948-5588    amy.krushelniski@hcahealthcare.com   
Principal Investigator: Rakesh Gaur         
Kansas City Cancer Centers - North Recruiting
Kansas City, Missouri, United States, 64154
Contact: Peter J. Van Veldhuizen    800-525-1483      
Principal Investigator: Peter J. Van Veldhuizen         
Kansas City Cancer Center - South Recruiting
Kansas City, Missouri, United States, 64131
Contact: Peter J. Van Veldhuizen    800-525-1483      
Principal Investigator: Peter J. Van Veldhuizen         
Saint Luke's Hospital of Kansas City Recruiting
Kansas City, Missouri, United States, 64111
Contact: Rakesh Gaur    913-948-5588    amy.krushelniski@hcahealthcare.com   
Principal Investigator: Rakesh Gaur         
Truman Medical Center Recruiting
Kansas City, Missouri, United States, 64108
Contact: Peter J. Van Veldhuizen    800-525-1483      
Principal Investigator: Peter J. Van Veldhuizen         
Saint Luke's Cancer Institute Terminated
Kansas City, Missouri, United States, 64111
Research Medical Center Recruiting
Kansas City, Missouri, United States, 64132
Contact: Rakesh Gaur    913-948-5588    amy.krushelniski@hcahealthcare.com   
Principal Investigator: Rakesh Gaur         
North Kansas City Hospital Recruiting
Kansas City, Missouri, United States, 64116
Contact: Rakesh Gaur    913-948-5588    amy.krushelniski@hcahealthcare.com   
Principal Investigator: Rakesh Gaur         
Kansas City Cancer Center-Lee's Summit Recruiting
Lee's Summit, Missouri, United States, 64064
Contact: Peter J. Van Veldhuizen    800-525-1483      
Principal Investigator: Peter J. Van Veldhuizen         
Saint Luke's East - Lee's Summit Recruiting
Lee's Summit, Missouri, United States, 64086
Contact: Rakesh Gaur    913-948-5588    amy.krushelniski@hcahealthcare.com   
Principal Investigator: Rakesh Gaur         
Liberty Radiation Oncology Clinic Recruiting
Liberty, Missouri, United States, 64068
Contact: Rakesh Gaur    913-948-5588    amy.krushelniski@hcahealthcare.com   
Principal Investigator: Rakesh Gaur         
Phelps County Regional Medical Center Recruiting
Rolla, Missouri, United States, 65401
Contact: Jay W. Carlson    888-244-6061    sherrijr@iora.org   
Principal Investigator: Jay W. Carlson         
Saint John's Clinic-Rolla-Cancer and Hematology Recruiting
Rolla, Missouri, United States, 65401
Contact: Robert L. Carolla    417-269-4520      
Principal Investigator: Robert L. Carolla         
Saint Joseph Oncology Inc Recruiting
Saint Joseph, Missouri, United States, 64507
Contact: Rakesh Gaur    913-948-5588    amy.krushelniski@hcahealthcare.com   
Principal Investigator: Rakesh Gaur         
Heartland Regional Medical Center Recruiting
Saint Joseph, Missouri, United States, 64506
Contact: Rakesh Gaur    913-948-5588    amy.krushelniski@hcahealthcare.com   
Principal Investigator: Rakesh Gaur         
Comprehensive Cancer Care PC Terminated
Saint Louis, Missouri, United States, 63141
Saint John's Mercy Medical Center Recruiting
Saint Louis, Missouri, United States, 63141
Contact: Robert L. Carolla    417-269-4520      
Principal Investigator: Robert L. Carolla         
Saint Louis Cancer and Breast Institute-South City Recruiting
Saint Louis, Missouri, United States, 63109
Contact: Jay W. Carlson    888-244-6061    sherrijr@iora.org   
Principal Investigator: Jay W. Carlson         
Saint Louis-Cape Girardeau CCOP Withdrawn
Saint Louis, Missouri, United States, 63141
Missouri Baptist Medical Center Recruiting
Saint Louis, Missouri, United States, 63131
Contact: Alan P. Lyss    800-392-0936      
Principal Investigator: Alan P. Lyss         
Cox Medical Center Recruiting
Springfield, Missouri, United States, 65807
Contact: Jay W. Carlson    888-244-6061    sherrijr@iora.org   
Principal Investigator: Jay W. Carlson         
Ozark Health Ventures LLC dba Cancer Research for The Ozarks Springfield Recruiting
Springfield, Missouri, United States, 65802
Contact: Jay W. Carlson    888-244-6061    sherrijr@iora.org   
Principal Investigator: Jay W. Carlson         
Saint John's Hospital Recruiting
Springfield, Missouri, United States, 65804
Contact: Robert L. Carolla    417-269-4520      
Principal Investigator: Robert L. Carolla         
United States, Montana
Billings Clinic Recruiting
Billings, Montana, United States, 59107-7000
Contact: Benjamin T. Marchello    800-648-6274      
Principal Investigator: Benjamin T. Marchello         
Saint Vincent Healthcare Recruiting
Billings, Montana, United States, 59101
Contact: Benjamin T. Marchello    800-648-6274      
Principal Investigator: Benjamin T. Marchello         
Montana Cancer Consortium CCOP Recruiting
Billings, Montana, United States, 59101
Contact: Benjamin T. Marchello    800-648-6274      
Principal Investigator: Benjamin T. Marchello         
Bozeman Deaconess Hospital Recruiting
Bozeman, Montana, United States, 59715
Contact: Benjamin T. Marchello    800-648-6274      
Principal Investigator: Benjamin T. Marchello         
Saint James Community Hospital and Cancer Treatment Center Recruiting
Butte, Montana, United States, 59701
Contact: Benjamin T. Marchello    800-648-6274      
Principal Investigator: Benjamin T. Marchello         
Benefis Healthcare- Sletten Cancer Institute Recruiting
Great Falls, Montana, United States, 59405
Contact: Grant W. Harrer    406-731-8217      
Principal Investigator: Grant W. Harrer         
Big Sky Oncology Active, not recruiting
Great Falls, Montana, United States, 59405
Saint Peter's Community Hospital Recruiting
Helena, Montana, United States, 59601
Contact: Benjamin T. Marchello    800-648-6274      
Principal Investigator: Benjamin T. Marchello         
Kalispell Regional Medical Center Recruiting
Kalispell, Montana, United States, 59901
Contact: Benjamin T. Marchello    800-648-6274      
Principal Investigator: Benjamin T. Marchello         
Montana Cancer Specialists Recruiting
Missoula, Montana, United States, 59802
Contact: Benjamin T. Marchello    800-648-6274      
Principal Investigator: Benjamin T. Marchello         
Saint Patrick Hospital - Community Hospital Recruiting
Missoula, Montana, United States, 59802
Contact: Benjamin T. Marchello    800-648-6274      
Principal Investigator: Benjamin T. Marchello         
United States, Nebraska
Good Samaritan Hospital Recruiting
Kearney, Nebraska, United States, 68847
Contact: George K. Bascom    308-865-7963      
Principal Investigator: George K. Bascom         
United States, New Jersey
Cooper Hospital University Medical Center Recruiting
Camden, New Jersey, United States, 08103
Contact: Stephen S. Grubbs    302-733-6227      
Principal Investigator: Stephen S. Grubbs         
Monmouth Medical Center Recruiting
Long Branch, New Jersey, United States, 07740
Contact: Seth M. Cohen    212-523-4000      
Principal Investigator: Seth M. Cohen         
UMDNJ - New Jersey Medical School Recruiting
Newark, New Jersey, United States, 07103
Contact: Robert Wieder    732-235-8675      
Principal Investigator: Robert Wieder         
United States, New York
Arnot Ogden Medical Center Recruiting
Elmira, New York, United States, 14905
Contact: Jonathan W. Friedberg    585-275-5830      
Principal Investigator: Jonathan W. Friedberg         
Glens Falls Hospital Recruiting
Glens Falls, New York, United States, 12801
Contact: Eric A. Pillemer    518-926-6700      
Principal Investigator: Eric A. Pillemer         
New York University Langone Medical Center Recruiting
New York, New York, United States, 10016
Contact: Lawrence P. Leichman    212-263-4434    prmc.coordinator@nyumc.org   
Principal Investigator: Lawrence P. Leichman         
University of Rochester Recruiting
Rochester, New York, United States, 14642
Contact: Jonathan W. Friedberg    585-275-5830      
Principal Investigator: Jonathan W. Friedberg         
United States, North Carolina
Randolph Hospital Recruiting
Asheboro, North Carolina, United States, 27203
Contact: Peter Rubin    336-832-0821      
Principal Investigator: Peter Rubin         
Wayne Memorial Hospital Recruiting
Goldsboro, North Carolina, United States, 27534
Contact: James N. Atkins    919-580-0000      
Principal Investigator: James N. Atkins         
Cone Health Cancer Center Recruiting
Greensboro, North Carolina, United States, 27403
Contact: Peter Rubin    336-832-0821      
Principal Investigator: Peter Rubin         
Margaret R Pardee Memorial Hospital Recruiting
Hendersonville, North Carolina, United States, 28791
Contact: James E. Radford    828-696-4716      
Principal Investigator: James E. Radford         
Park Ridge Hospital Breast Health Center Recruiting
Hendersonville, North Carolina, United States, 28792
Contact: James D. Bearden    800-486-5941      
Principal Investigator: James D. Bearden         
Kinston Medical Specialists PA Recruiting
Kinston, North Carolina, United States, 28501
Contact: Peter R. Watson    252-559-2200      
Principal Investigator: Peter R. Watson         
FirstHealth of the Carolinas-Moore Regional Hosiptal Recruiting
Pinehurst, North Carolina, United States, 28374
Contact: Charles S. Kuzma    910-715-2200      
Principal Investigator: Charles S. Kuzma         
Annie Penn Memorial Hospital Recruiting
Reidsville, North Carolina, United States, 27320
Contact: Peter Rubin    336-832-0821      
Principal Investigator: Peter Rubin         
Rutherford Hospital Active, not recruiting
Rutherfordton, North Carolina, United States, 28139
Iredell Memorial Hospital Recruiting
Statesville, North Carolina, United States, 28677
Contact: Ruby A. Grimm    704-873-5661      
Principal Investigator: Ruby A. Grimm         
United States, North Dakota
Sanford Clinic North-Fargo Recruiting
Fargo, North Dakota, United States, 58122
Contact: Preston D. Steen    701-234-6161      
Principal Investigator: Preston D. Steen         
Roger Maris Cancer Center Recruiting
Fargo, North Dakota, United States, 58122
Contact: Preston D. Steen    701-234-6161      
Principal Investigator: Preston D. Steen         
Sanford Medical Center-Fargo Recruiting
Fargo, North Dakota, United States, 58122
Contact: Preston D. Steen    701-234-6161      
Principal Investigator: Preston D. Steen         
Altru Cancer Center Recruiting
Grand Forks, North Dakota, United States, 58201
Contact: Grant R. Seeger    701-780-6520      
Principal Investigator: Grant R. Seeger         
United States, Ohio
Summa Akron City Hospital Recruiting
Akron, Ohio, United States, 44304
Contact: Jennifer E. Payne    330-375-6101      
Principal Investigator: Jennifer E. Payne         
Akron General Medical Center Recruiting
Akron, Ohio, United States, 44307
Contact: Esther H. Rehmus    330-344-6348      
Principal Investigator: Esther H. Rehmus         
Summa Barberton Hospital Recruiting
Barberton, Ohio, United States, 44203
Contact: Jennifer E. Payne    330-375-6101      
Principal Investigator: Jennifer E. Payne         
Toledo Clinic Cancer Centers-Bowling Green Recruiting
Bowling Green, Ohio, United States, 43402
Contact: Rex B. Mowat    517-265-0116      
Principal Investigator: Rex B. Mowat         
University of Cincinnati Recruiting
Cincinnati, Ohio, United States, 45267
Contact: John C. Morris    513-558-4553    uchealthnews@uc.edu   
Principal Investigator: John C. Morris         
MetroHealth Medical Center Recruiting
Cleveland, Ohio, United States, 44109
Contact: Bruce J. Averbook    216-778-8526    kbauchens@metrohealth.org   
Principal Investigator: Bruce J. Averbook         
Ohio State University Medical Center Recruiting
Columbus, Ohio, United States, 43210
Contact: Tanios S. Bekaii-Saab    866-627-7616    osu@emergingmed.com   
Principal Investigator: Tanios S. Bekaii-Saab         
Samaritan North Health Center Recruiting
Dayton, Ohio, United States, 45415
Contact: Howard M. Gross    765-983-3000      
Principal Investigator: Howard M. Gross         
Good Samaritan Hospital - Dayton Recruiting
Dayton, Ohio, United States, 45406
Contact: Howard M. Gross    765-983-3000      
Principal Investigator: Howard M. Gross         
Dayton CCOP Recruiting
Dayton, Ohio, United States, 45420
Contact: Howard M. Gross    317-783-8918      
Principal Investigator: Howard M. Gross         
Grandview Hospital Recruiting
Dayton, Ohio, United States, 45405
Contact: Howard M. Gross    317-783-8918      
Principal Investigator: Howard M. Gross         
Miami Valley Hospital Recruiting
Dayton, Ohio, United States, 45409
Contact: Howard M. Gross    317-783-8918      
Principal Investigator: Howard M. Gross         
Community Health Partners Regional Medical Center Recruiting
Elyria, Ohio, United States, 44035
Contact: Rex B. Mowat    517-265-0116      
Principal Investigator: Rex B. Mowat         
Hematology Oncology Center Incorporated Recruiting
Elyria, Ohio, United States, 44035
Contact: Rex B. Mowat    517-265-0116      
Principal Investigator: Rex B. Mowat         
Blanchard Valley Hospital Recruiting
Findlay, Ohio, United States, 45840
Contact: Howard M. Gross    317-783-8918      
Principal Investigator: Howard M. Gross         
Atrium Medical Center-Middletown Regional Hospital Recruiting
Franklin, Ohio, United States, 45005-1066
Contact: Howard M. Gross    317-783-8918      
Principal Investigator: Howard M. Gross         
Wayne Hospital Recruiting
Greenville, Ohio, United States, 45331
Contact: Howard M. Gross    317-783-8918      
Principal Investigator: Howard M. Gross         
Kettering Medical Center Recruiting
Kettering, Ohio, United States, 45429
Contact: Howard M. Gross    317-783-8918      
Principal Investigator: Howard M. Gross         
Saint Rita's Medical Center Recruiting
Lima, Ohio, United States, 45801
Contact: Henry Gerad    419-226-9617      
Principal Investigator: Henry Gerad         
Lima Memorial Hospital Recruiting
Lima, Ohio, United States, 45804
Contact: Rex B. Mowat    517-265-0116      
Principal Investigator: Rex B. Mowat         
Toledo Radiation Oncology at Northwest Ohio Onocolgy Center Recruiting
Maumee, Ohio, United States, 43537
Contact: Rex B. Mowat    517-265-0116      
Principal Investigator: Rex B. Mowat         
Toledo Clinic Cancer Centers-Maumee Recruiting
Maumee, Ohio, United States, 43537-1839
Contact: Rex B. Mowat    517-265-0116      
Principal Investigator: Rex B. Mowat         
Saint Charles Hospital Recruiting
Oregon, Ohio, United States, 43616
Contact: Rex B. Mowat    517-265-0116      
Principal Investigator: Rex B. Mowat         
Toledo Clinic Cancer Centers-Oregon Recruiting
Oregon, Ohio, United States, 43616
Contact: Rex B. Mowat    517-265-0116      
Principal Investigator: Rex B. Mowat         
Flower Hospital Recruiting
Sylvania, Ohio, United States, 43560
Contact: Rex B. Mowat    517-265-0116      
Principal Investigator: Rex B. Mowat         
Mercy Hospital of Tiffin Recruiting
Tiffin, Ohio, United States, 44883
Contact: Rex B. Mowat    517-265-0116      
Principal Investigator: Rex B. Mowat         
The Toledo Hospital/Toledo Children's Hospital Recruiting
Toledo, Ohio, United States, 43606
Contact: Rex B. Mowat    517-265-0116      
Principal Investigator: Rex B. Mowat         
Toledo Community Hospital Oncology Program CCOP Recruiting
Toledo, Ohio, United States, 43617
Contact: Rex B. Mowat    517-265-0116      
Principal Investigator: Rex B. Mowat         
Mercy Cancer Center at Saint Anne Mercy Hospital Recruiting
Toledo, Ohio, United States, 43623
Contact: Rex B. Mowat    517-265-0116      
Principal Investigator: Rex B. Mowat         
Saint Vincent Mercy Medical Center Recruiting
Toledo, Ohio, United States, 43608
Contact: Rex B. Mowat    517-265-0116      
Principal Investigator: Rex B. Mowat         
Toledo Clinic Cancer Centers-Toledo Recruiting
Toledo, Ohio, United States, 43623
Contact: Rex B. Mowat    517-265-0116      
Principal Investigator: Rex B. Mowat         
University of Toledo Recruiting
Toledo, Ohio, United States, 43614
Contact: Rex B. Mowat    517-265-0116      
Principal Investigator: Rex B. Mowat         
Upper Valley Medical Center Recruiting
Troy, Ohio, United States, 45373
Contact: Howard M. Gross    317-783-8918      
Principal Investigator: Howard M. Gross         
Fulton County Health Center Recruiting
Wauseon, Ohio, United States, 43567
Contact: Rex B. Mowat    517-265-0116      
Principal Investigator: Rex B. Mowat         
Wright-Patterson Medical Center Recruiting
Wright-Patterson Afb, Ohio, United States, 45433-5529
Contact: Brandon J. Cutler    937-257-1398      
Principal Investigator: Brandon J. Cutler         
Greene Memorial Hospital Recruiting
Xenia, Ohio, United States, 45385
Contact: Howard M. Gross    317-783-8918      
Principal Investigator: Howard M. Gross         
United States, Oklahoma
University of Oklahoma Health Sciences Center Recruiting
Oklahoma City, Oklahoma, United States, 73104
Contact: George B. Selby    405-271-4272    julie-traylor@ouhsc.edu   
Principal Investigator: George B. Selby         
Natalie W Bryant Cancer Center Recruiting
Tulsa, Oklahoma, United States, 74136
Contact: Joseph P. Lynch    918-494-2200      
Principal Investigator: Joseph P. Lynch         
United States, Oregon
Clackamas Radiation Oncology Center Recruiting
Clackamas, Oregon, United States, 97015
Contact: Alison K. Conlin    503-215-6412      
Principal Investigator: Alison K. Conlin         
Providence Milwaukie Hospital Recruiting
Milwaukie, Oregon, United States, 97222
Contact: Alison K. Conlin    503-215-6412      
Principal Investigator: Alison K. Conlin         
Providence Newberg Medical Center Recruiting
Newberg, Oregon, United States, 97132
Contact: Alison K. Conlin    503-215-6412      
Principal Investigator: Alison K. Conlin         
Providence Willamette Falls Medical Center Recruiting
Oregon City, Oregon, United States, 97045
Contact: Alison K. Conlin    503-215-6412      
Principal Investigator: Alison K. Conlin         
Providence Portland Medical Center Recruiting
Portland, Oregon, United States, 97213
Contact: Alison K. Conlin    503-215-6412      
Principal Investigator: Alison K. Conlin         
Providence Saint Vincent Medical Center Recruiting
Portland, Oregon, United States, 97225
Contact: Alison K. Conlin    503-215-6412      
Principal Investigator: Alison K. Conlin         
Columbia River Oncology Program Recruiting
Portland, Oregon, United States, 97225
Contact: Alison K. Conlin    503-215-6412      
Principal Investigator: Alison K. Conlin         
United States, Pennsylvania
Lehigh Valley Hospital Recruiting
Allentown, Pennsylvania, United States, 18105
Contact: Eliot L. Friedman    610-402-2273      
Principal Investigator: Eliot L. Friedman         
Lehigh Valley Hospital - Muhlenberg Active, not recruiting
Bethlehem, Pennsylvania, United States, 18017
Adams Cancer Center Recruiting
Gettysburg, Pennsylvania, United States, 17325
Contact: Amir Tabatabai    877-441-7957      
Principal Investigator: Amir Tabatabai         
Cherry Tree Cancer Center Recruiting
Hanover, Pennsylvania, United States, 17331
Contact: Amir Tabatabai    877-441-7957      
Principal Investigator: Amir Tabatabai         
Lancaster General Hospital Recruiting
Lancaster, Pennsylvania, United States, 17604
Contact: Nandi J. Reddy    717-544-5511      
Principal Investigator: Nandi J. Reddy         
Fox Chase Cancer Center Recruiting
Philadelphia, Pennsylvania, United States, 19111-2497
Contact: Barbara A. Burtness    215-728-4790      
Principal Investigator: Barbara A. Burtness         
University of Pittsburgh Recruiting
Pittsburgh, Pennsylvania, United States, 15232
Contact: Michael K. Gibson    800-641-2422      
Principal Investigator: Michael K. Gibson         
York Hospital Recruiting
York, Pennsylvania, United States, 17405
Contact: Amir Tabatabai    877-441-7957      
Principal Investigator: Amir Tabatabai         
United States, South Carolina
AnMed Health Cancer Center Recruiting
Anderson, South Carolina, United States, 29621
Contact: James D. Bearden    800-486-5941      
Principal Investigator: James D. Bearden         
AnMed Health Hospital Recruiting
Anderson, South Carolina, United States, 29621
Contact: James D. Bearden    800-486-5941      
Principal Investigator: James D. Bearden         
Roper Hospital Recruiting
Charleston, South Carolina, United States, 29401
Contact: James M. Orcutt    843-720-8386    elizabeth.strojny@roperstfrancis.com   
Principal Investigator: James M. Orcutt         
Greenville Memorial Hospital Recruiting
Greenville, South Carolina, United States, 29605
Contact: Jeffrey K. Giguere    864-241-6251      
Principal Investigator: Jeffrey K. Giguere         
Greenville CCOP Recruiting
Greenville, South Carolina, United States, 29615
Contact: Jeffrey K. Giguere    864-241-6251      
Principal Investigator: Jeffrey K. Giguere         
Cancer Centers of the Carolinas - Faris Recruiting
Greenville, South Carolina, United States, 29605
Contact: Jeffrey K. Giguere    864-241-6251      
Principal Investigator: Jeffrey K. Giguere         
Cancer Centers of the Carolinas - Grove Commons Recruiting
Greenville, South Carolina, United States, 29605
Contact: Jeffrey K. Giguere    864-241-6251      
Principal Investigator: Jeffrey K. Giguere         
Saint Francis Hospital Recruiting
Greenville, South Carolina, United States, 29601
Contact: James D. Bearden    800-486-5941      
Principal Investigator: James D. Bearden         
Gibbs Cancer Center-Pelham Active, not recruiting
Greer, South Carolina, United States, 29651
Cancer Centers of the Carolinas-Greer Medical Oncology Recruiting
Greer, South Carolina, United States, 29650
Contact: Jeffrey K. Giguere    864-241-6251      
Principal Investigator: Jeffrey K. Giguere         
Cancer Centers of the Carolinas - Seneca Recruiting
Seneca, South Carolina, United States, 29672
Contact: Jeffrey K. Giguere    864-241-6251      
Principal Investigator: Jeffrey K. Giguere         
Cancer Centers of the Carolinas - Spartanburg Recruiting
Spartanburg, South Carolina, United States, 29307
Contact: Jeffrey K. Giguere    864-241-6251      
Principal Investigator: Jeffrey K. Giguere         
Spartanburg Regional Medical Center Recruiting
Spartanburg, South Carolina, United States, 29303
Contact: James D. Bearden    800-486-5941      
Principal Investigator: James D. Bearden         
Upstate Carolina CCOP Recruiting
Spartanburg, South Carolina, United States, 29303
Contact: James D. Bearden    800-486-5941      
Principal Investigator: James D. Bearden         
United States, South Dakota
Rapid City Regional Hospital Recruiting
Rapid City, South Dakota, United States, 57701
Contact: Richard C. Tenglin    605-716-3982    research@rcrh.org   
Principal Investigator: Richard C. Tenglin         
Avera Cancer Institute Active, not recruiting
Sioux Falls, South Dakota, United States, 57105
Sanford Cancer Center-Oncology Clinic Recruiting
Sioux Falls, South Dakota, United States, 57104
Contact: Miroslaw A. Mazurczak    605-328-1367      
Principal Investigator: Miroslaw A. Mazurczak         
Sanford USD Medical Center - Sioux Falls Recruiting
Sioux Falls, South Dakota, United States, 57117-5134
Contact: Miroslaw A. Mazurczak    605-328-1367      
Principal Investigator: Miroslaw A. Mazurczak         
United States, Texas
Baylor College of Medicine Recruiting
Houston, Texas, United States, 77030
Contact: Benjamin L. Musher    713-798-1354    burton@bcm.edu   
Principal Investigator: Benjamin L. Musher         
Ben Taub General Hospital Recruiting
Houston, Texas, United States, 77030
Contact: Benjamin L. Musher    713-798-1354    burton@bcm.edu   
Principal Investigator: Benjamin L. Musher         
Veterans Administration Medical Center Recruiting
Houston, Texas, United States, 77030
Contact: Benjamin L. Musher    713-798-1354    burton@bcm.edu   
Principal Investigator: Benjamin L. Musher         
Southwest Oncology Group (SWOG) Research Base Recruiting
San Antonio, Texas, United States, 78245
Contact: Syma Iqbal    323-865-3907    iqbal@usc.edu   
Principal Investigator: Syma Iqbal         
United States, Virginia
Fredericksburg Oncology Inc Recruiting
Fredericksburg, Virginia, United States, 22401
Contact: Rex B. Mowat    517-265-0116      
Principal Investigator: Rex B. Mowat         
Virginia Commonwealth University Recruiting
Richmond, Virginia, United States, 23298
Contact: James E. Shaw    804-628-1939      
Principal Investigator: James E. Shaw         
United States, Washington
Cancer Care Center at Island Hospital Recruiting
Anacortes, Washington, United States, 98221
Contact: Gary E. Goodman    206-386-2323    patra.grevstad@swedish.org   
Principal Investigator: Gary E. Goodman         
Auburn Regional Medical Center Recruiting
Auburn, Washington, United States, 98002
Contact: Yoshio Inoue    253-403-2394      
Principal Investigator: Yoshio Inoue         
Overlake Hospital Medical Center Recruiting
Bellevue, Washington, United States, 98004
Contact: Yoshio Inoue    253-403-2394      
Principal Investigator: Yoshio Inoue         
PeaceHealth Saint Joseph Medical Center Recruiting
Bellingham, Washington, United States, 98225
Contact: Gary E. Goodman    206-386-2323    patra.grevstad@swedish.org   
Principal Investigator: Gary E. Goodman         
Harrison Bremerton Hematology and Oncology Recruiting
Bremerton, Washington, United States, 98310
Contact: Gary E. Goodman    206-386-2323    patra.grevstad@swedish.org   
Principal Investigator: Gary E. Goodman         
Highline Medical Center-Main Campus Recruiting
Burien, Washington, United States, 98166
Contact: Gary E. Goodman    206-386-2323    patra.grevstad@swedish.org   
Principal Investigator: Gary E. Goodman         
Providence Centralia Hospital Recruiting
Centralia, Washington, United States, 98531
Contact: Yoshio Inoue    253-403-2394      
Principal Investigator: Yoshio Inoue         
Swedish Medical Center-Edmonds Active, not recruiting
Edmonds, Washington, United States, 98026
Providence Regional Cancer Partnership Recruiting
Everett, Washington, United States, 98201
Contact: Yoshio Inoue    253-403-2394      
Principal Investigator: Yoshio Inoue         
Saint Francis Hospital Recruiting
Federal Way, Washington, United States, 98003
Contact: Yoshio Inoue    253-403-2394      
Principal Investigator: Yoshio Inoue         
Swedish Cancer Institute-Issaquah Recruiting
Issaquah, Washington, United States, 98029
Contact: Gary E. Goodman    206-386-2323    patra.grevstad@swedish.org   
Principal Investigator: Gary E. Goodman         
Columbia Basin Hematology and Oncology PLLC Recruiting
Kennewick, Washington, United States, 99336
Contact: Gary E. Goodman    206-386-2323    patra.grevstad@swedish.org   
Principal Investigator: Gary E. Goodman         
Skagit Valley Hospital Recruiting
Mount Vernon, Washington, United States, 98274
Contact: Gary E. Goodman    206-386-2323    patra.grevstad@swedish.org   
Principal Investigator: Gary E. Goodman         
Providence - Saint Peter Hospital Recruiting
Olympia, Washington, United States, 98506-5166
Contact: Yoshio Inoue    253-403-2394      
Principal Investigator: Yoshio Inoue         
Harrison Poulsbo Hematology and Oncology Recruiting
Poulsbo, Washington, United States, 98370
Contact: Gary E. Goodman    206-386-2323    patra.grevstad@swedish.org   
Principal Investigator: Gary E. Goodman         
Good Samaritan Community Hospital Recruiting
Puyallup, Washington, United States, 98372
Contact: Yoshio Inoue    253-403-2394      
Principal Investigator: Yoshio Inoue         
Harborview Medical Center Recruiting
Seattle, Washington, United States, 98104
Contact: Gary E. Goodman    206-386-2323    patra.grevstad@swedish.org   
Principal Investigator: Gary E. Goodman         
Minor and James Medical PLLC Recruiting
Seattle, Washington, United States, 98104
Contact: Gary E. Goodman    206-386-2323    patra.grevstad@swedish.org   
Principal Investigator: Gary E. Goodman         
Fred Hutchinson Cancer Research Center/University of Washington Cancer Consortium Recruiting
Seattle, Washington, United States, 98109
Contact: Gary E. Goodman    206-386-2323    patra.grevstad@swedish.org   
Principal Investigator: Gary E. Goodman         
Group Health Cooperative Recruiting
Seattle, Washington, United States, 98112
Contact: Gary E. Goodman    206-386-2323    patra.grevstad@swedish.org   
Principal Investigator: Gary E. Goodman         
Swedish Medical Center-Ballard Campus Recruiting
Seattle, Washington, United States, 98107
Contact: Gary E. Goodman    206-386-2323    patra.grevstad@swedish.org   
Principal Investigator: Gary E. Goodman         
The Polyclinic Active, not recruiting
Seattle, Washington, United States, 98122
University of Washington Medical Center Recruiting
Seattle, Washington, United States, 98195
Contact: Gary E. Goodman    206-386-2323    patra.grevstad@swedish.org   
Principal Investigator: Gary E. Goodman         
Swedish Medical Center-First Hill Recruiting
Seattle, Washington, United States, 98122-4307
Contact: Gary E. Goodman    206-386-2323    patra.grevstad@swedish.org   
Principal Investigator: Gary E. Goodman         
United General Hospital Recruiting
Sedro-Woolley, Washington, United States, 98284
Contact: Gary E. Goodman    206-386-2323    patra.grevstad@swedish.org   
Principal Investigator: Gary E. Goodman         
Evergreen Hematology and Oncology PS Recruiting
Spokane, Washington, United States, 99218
Contact: Gary E. Goodman    206-386-2323    patra.grevstad@swedish.org   
Principal Investigator: Gary E. Goodman         
Cancer Care Northwest - Spokane South Recruiting
Spokane, Washington, United States, 99202
Contact: Gary E. Goodman    206-386-2323    patra.grevstad@swedish.org   
Principal Investigator: Gary E. Goodman         
Rockwood Clinic Recruiting
Spokane, Washington, United States, 99220
Contact: Corliss L. Newman    509-755-5800      
Principal Investigator: Corliss L. Newman         
Saint Joseph Medical Center Recruiting
Tacoma, Washington, United States, 98405
Contact: Yoshio Inoue    253-403-2394      
Principal Investigator: Yoshio Inoue         
Allenmore Hospital Recruiting
Tacoma, Washington, United States, 98405
Contact: Yoshio Inoue    253-403-2394      
Principal Investigator: Yoshio Inoue         
Multicare Health System Recruiting
Tacoma, Washington, United States, 98415
Contact: Yoshio Inoue    253-403-2394      
Principal Investigator: Yoshio Inoue         
Northwest CCOP Recruiting
Tacoma, Washington, United States, 98405
Contact: Yoshio Inoue    253-403-2394      
Principal Investigator: Yoshio Inoue         
Saint Clare Hospital Recruiting
Tacoma, Washington, United States, 98499
Contact: Yoshio Inoue    253-403-2394      
Principal Investigator: Yoshio Inoue         
PeaceHealth Southwest Medical Center Recruiting
Vancouver, Washington, United States, 98664
Contact: Alison K. Conlin    503-215-6412      
Principal Investigator: Alison K. Conlin         
Northwest Cancer Specialists Recruiting
Vancouver, Washington, United States, 98684
Contact: Alison K. Conlin    503-215-6412      
Principal Investigator: Alison K. Conlin         
Wenatchee Valley Medical Center Recruiting
Wenatchee, Washington, United States, 98801
Contact: Gary E. Goodman    206-386-2323    patra.grevstad@swedish.org   
Principal Investigator: Gary E. Goodman         
United States, Wisconsin
Langlade Hospital and Cancer Center Recruiting
Antigo, Wisconsin, United States, 54409
Contact: Christopher G. Peterson    877-405-6866      
Principal Investigator: Christopher G. Peterson         
Sacred Heart Hospital Recruiting
Eau Claire, Wisconsin, United States, 54701
Contact: Elena N. Theodosiou    715-389-4457      
Principal Investigator: Elena N. Theodosiou         
Marshfield Clinic Cancer Center at Sacred Heart Recruiting
Eau Claire, Wisconsin, United States, 54701
Contact: Elena N. Theodosiou    715-389-4457      
Principal Investigator: Elena N. Theodosiou         
Saint Mary's Hospital Recruiting
Green Bay, Wisconsin, United States, 54303
Contact: Matthew L. Ryan    800-432-6049      
Principal Investigator: Matthew L. Ryan         
Green Bay Oncology at Saint Vincent Hospital Recruiting
Green Bay, Wisconsin, United States, 54301-3526
Contact: Matthew L. Ryan    800-432-6049      
Principal Investigator: Matthew L. Ryan         
Green Bay Oncology Limited at Saint Mary's Hospital Recruiting
Green Bay, Wisconsin, United States, 54303
Contact: Matthew L. Ryan    800-432-6049      
Principal Investigator: Matthew L. Ryan         
Saint Vincent Hospital Recruiting
Green Bay, Wisconsin, United States, 54301
Contact: Matthew L. Ryan    800-432-6049      
Principal Investigator: Matthew L. Ryan         
Gundersen Lutheran Recruiting
La Crosse, Wisconsin, United States, 54601
Contact: Kurt Oettel    608-775-2385    cancerctr@gundluth.org   
Principal Investigator: Kurt Oettel         
University of Wisconsin Hospital and Clinics Recruiting
Madison, Wisconsin, United States, 53792
Contact: Sam J. Lubner    877-405-6866      
Principal Investigator: Sam J. Lubner         
Holy Family Memorial Hospital Recruiting
Manitowoc, Wisconsin, United States, 54221
Contact: Matthew L. Ryan    800-432-6049      
Principal Investigator: Matthew L. Ryan         
Bay Area Medical Center Recruiting
Marinette, Wisconsin, United States, 54143
Contact: Matthew L. Ryan    800-432-6049      
Principal Investigator: Matthew L. Ryan         
Marshfield Clinic Recruiting
Marshfield, Wisconsin, United States, 54449
Contact: Elena N. Theodosiou    715-389-4457      
Principal Investigator: Elena N. Theodosiou         
Saint Joseph's Hospital Recruiting
Marshfield, Wisconsin, United States, 54449
Contact: Elena N. Theodosiou    715-389-4457      
Principal Investigator: Elena N. Theodosiou         
Froedtert and the Medical College of Wisconsin Withdrawn
Milwaukee, Wisconsin, United States, 53226
Marshfield Clinic-Minocqua Center Recruiting
Minocqua, Wisconsin, United States, 54548
Contact: Elena N. Theodosiou    715-389-4457      
Principal Investigator: Elena N. Theodosiou         
Green Bay Oncology - Oconto Falls Recruiting
Oconto Falls, Wisconsin, United States, 54154
Contact: Matthew L. Ryan    800-432-6049      
Principal Investigator: Matthew L. Ryan         
Saint Mary's Hospital Recruiting
Rhinelander, Wisconsin, United States, 54501
Contact: Elena N. Theodosiou    715-389-4457      
Principal Investigator: Elena N. Theodosiou         
Marshfield Clinic at James Beck Cancer Center Recruiting
Rhinelander, Wisconsin, United States, 54501
Contact: Elena N. Theodosiou    715-389-4457      
Principal Investigator: Elena N. Theodosiou         
Marshfield Clinic-Rice Lake Center Recruiting
Rice Lake, Wisconsin, United States, 54868
Contact: Elena N. Theodosiou    715-389-4457      
Principal Investigator: Elena N. Theodosiou         
Saint Nicholas Hospital Recruiting
Sheboygan, Wisconsin, United States, 53081
Contact: Matthew L. Ryan    800-432-6049      
Principal Investigator: Matthew L. Ryan         
Saint Michael's Hospital Recruiting
Stevens Point, Wisconsin, United States, 54481
Contact: Elena N. Theodosiou    715-389-4457      
Principal Investigator: Elena N. Theodosiou         
Marshfield Clinic Cancer Care at Saint Michael's Hospital Recruiting
Stevens Point, Wisconsin, United States, 54481
Contact: Elena N. Theodosiou    715-389-4457      
Principal Investigator: Elena N. Theodosiou         
Green Bay Oncology - Sturgeon Bay Recruiting
Sturgeon Bay, Wisconsin, United States, 54235
Contact: Matthew L. Ryan    800-432-6049      
Principal Investigator: Matthew L. Ryan         
Aspirus Regional Cancer Center Recruiting
Wausau, Wisconsin, United States, 54401
Contact: Christopher G. Peterson    877-405-6866      
Principal Investigator: Christopher G. Peterson         
Marshfield Clinic - Weston Center Recruiting
Weston, Wisconsin, United States, 54476
Contact: Elena N. Theodosiou    715-389-4457      
Principal Investigator: Elena N. Theodosiou         
Saint Clare's Hospital Recruiting
Weston, Wisconsin, United States, 54476
Contact: Elena N. Theodosiou    715-389-4457      
Principal Investigator: Elena N. Theodosiou         
Marshfield Clinic - Wisconsin Rapids Center Recruiting
Wisconsin Rapids, Wisconsin, United States, 54494
Contact: Elena N. Theodosiou    715-389-4457      
Principal Investigator: Elena N. Theodosiou         
Riverview Hospital Recruiting
Wisconsin Rapids, Wisconsin, United States, 54494
Contact: Ronnie J. Kirschling    877-405-6866      
Principal Investigator: Ronnie J. Kirschling         
United States, Wyoming
Rocky Mountain Oncology Recruiting
Casper, Wyoming, United States, 82609
Contact: Benjamin T. Marchello    800-648-6274      
Principal Investigator: Benjamin T. Marchello         
Welch Cancer Center Recruiting
Sheridan, Wyoming, United States, 82801
Contact: Benjamin T. Marchello    800-648-6274      
Principal Investigator: Benjamin T. Marchello         
Sponsors and Collaborators
Southwest Oncology Group
Investigators
Principal Investigator: Syma Iqbal, MD University of Southern California
  More Information

Additional Information:
No publications provided

Responsible Party: Southwest Oncology Group
ClinicalTrials.gov Identifier: NCT01498289     History of Changes
Other Study ID Numbers: S1201, S1201, U10CA032102, NCI-2012-00096
Study First Received: December 22, 2011
Last Updated: January 13, 2014
Health Authority: United States: Federal Government

Keywords provided by Southwest Oncology Group:
recurrent esophageal cancer
stage IV esophageal cancer
recurrent gastric cancer
stage IV gastric cancer
adenocarcinoma of the gastroesophageal junction
stage IIIB gastric cancer
stage IIIC gastric cancer
stage IIIB esophageal cancer
stage IIIC esophageal cancer
adenocarcinoma of the esophagus
adenocarcinoma of the stomach

Additional relevant MeSH terms:
Adenocarcinoma
Esophageal Neoplasms
Stomach Neoplasms
Carcinoma
Neoplasms, Glandular and Epithelial
Neoplasms by Histologic Type
Neoplasms
Gastrointestinal Neoplasms
Digestive System Neoplasms
Neoplasms by Site
Head and Neck Neoplasms
Digestive System Diseases
Esophageal Diseases
Gastrointestinal Diseases
Stomach Diseases
Fluorouracil
Oxaliplatin
Irinotecan
Docetaxel
Camptothecin
Leucovorin
Levoleucovorin
Antimetabolites
Molecular Mechanisms of Pharmacological Action
Pharmacologic Actions
Antimetabolites, Antineoplastic
Antineoplastic Agents
Therapeutic Uses
Immunosuppressive Agents
Immunologic Factors

ClinicalTrials.gov processed this record on April 17, 2014