Trial record 1 of 1 for:    GOG 0273
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Chemotherapy Toxicity On Quality of Life in Older Patients With Stage I, Stage II, Stage III, or Stage IV Ovarian Epithelial, Primary Peritoneal Cavity, or Fallopian Tube Cancer

This study is currently recruiting participants.
Verified March 2014 by Gynecologic Oncology Group
Sponsor:
Collaborator:
Information provided by (Responsible Party):
Gynecologic Oncology Group
ClinicalTrials.gov Identifier:
NCT01366183
First received: June 2, 2011
Last updated: March 25, 2014
Last verified: March 2014
  Purpose

This trial studies the chemotherapy toxicity on quality of life in older patients with stage I, stage II, stage III, or stage IV ovarian epithelial, primary peritoneal cavity, or fallopian tube cancer. Learning about the side effects of chemotherapy in older patients may help doctors plan better ways to treat cancer.


Condition Intervention
Stage I Ovarian Epithelial Cancer
Stage I Primary Peritoneal Cavity Cancer
Stage IA Fallopian Tube Cancer
Stage IB Fallopian Tube Cancer
Stage IC Fallopian Tube Cancer
Stage II Ovarian Epithelial Cancer
Stage II Primary Peritoneal Cavity Cancer
Stage IIA Fallopian Tube Cancer
Stage IIB Fallopian Tube Cancer
Stage IIC Fallopian Tube Cancer
Stage III Ovarian Epithelial Cancer
Stage III Primary Peritoneal Cavity Cancer
Stage IIIA Fallopian Tube Cancer
Stage IIIB Fallopian Tube Cancer
Stage IIIC Fallopian Tube Cancer
Stage IV Fallopian Tube Cancer
Stage IV Ovarian Epithelial Cancer
Stage IV Primary Peritoneal Cavity Cancer
Other: pharmacological study
Other: questionnaire administration
Procedure: assessment of therapy complications
Other: quality-of-life assessment
Drug: carboplatin
Drug: paclitaxel
Biological: filgrastim

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Retrospective
Official Title: Chemotherapy Toxicity in Elderly Women With Ovarian, Primary Peritoneal or Fallopian Tube Cancer

Resource links provided by NLM:


Further study details as provided by Gynecologic Oncology Group:

Primary Outcome Measures:
  • Tolerance to study treatment, defined as completing four cycles of study treatment, without dose reductions or treatment delays of over seven days [ Time Frame: Up to 5 years ] [ Designated as safety issue: Yes ]
    Will be modeled with logistic regression using baseline IADL scores as a covariate. Exploratory analysis will evaluate baseline IADL scores adjusting for covariates such as: Charlson scale, nutritional status, or age.

  • Percent of women, who are 70 years or older, able to complete at least 4 cycles of treatment regardless of dose reduction and delays [ Time Frame: Up to 5 years ] [ Designated as safety issue: No ]
    While this percentage will be estimated for each study regimen separately, the targeted sample size will limit the width of the 95%-confidence interval for the marginal percentage so that it is no larger than 0.15.


Secondary Outcome Measures:
  • Changes in quality-of-life measured by FACT-O, FACT/GOG-Ntx-4 subscale, IADL, and ADL [ Time Frame: Baseline to up to 6 weeks after completion of course 4 ] [ Designated as safety issue: No ]
    The changes in FACT-O, FACT/GOG-Ntx-4 subscale, IADL, and ADL will be summarized descriptively as the differences of scores between pre and post chemotherapy. Assuming 80% of patients complete the assessment at the completion of chemotherapy, then a sample of 148 patients will provide 90% power to detect 5 unit changes in FACT-O, 0.5 unit change in FACT/GOG-Ntx subscale score, 1 unit change in IADL or ADL score using paired t-test at significant level of 0.05.

  • Changes in comorbidity index measured by the Charlson scale [ Time Frame: Baseline to up to 6 weeks after completion of course 4 ] [ Designated as safety issue: No ]
  • Changes in nutritional status measured by weight [ Time Frame: Baseline to up to 6 weeks after completion of course 4 ] [ Designated as safety issue: No ]
    The changes in weight will be summarized descriptively as the differences of scores between pre and post chemotherapy. The change of nutritional status after completing chemotherapy will be examined using McNemar's test.

  • Clinical response of elderly patients with ovarian, primary peritoneal cavity, or fallopian tube cancer [ Time Frame: Up to 5 years ] [ Designated as safety issue: No ]
  • Percent of patients reporting adverse events as assessed by the National Cancer Institute's Common Terminology Criteria for Adverse Events [ Time Frame: Up to 6 weeks after course 4 ] [ Designated as safety issue: Yes ]
    The probability of an adverse event will be estimated as the percent of patients reporting an adverse event out of all patients beginning treatment.


Other Outcome Measures:
  • Pharmacokinetic parameters including paclitaxel AUC, carboplatin AUC, paclitaxel total body clearance, and time that plasma paclitaxel concentration remains above threshold 0.05 uM/L [ Time Frame: Pre-dose, 1, 6, and 24 hours ] [ Designated as safety issue: No ]
    The observed pharmacokinetics of paclitaxel and carboplatin will be compared with published pharmacokinetic measures of paclitaxel and carboplatin in a descriptive fashion. No formal statistical testing will be performed for the comparisons.


Estimated Enrollment: 290
Study Start Date: August 2011
Estimated Primary Completion Date: December 2019 (Final data collection date for primary outcome measure)
Groups/Cohorts Assigned Interventions
Observational (quality of life questionnaire)

Patients receive chemotherapy comprising carboplatin, paclitaxel, and filgrastim (regimen 1) or carboplatin alone (regimen 2) every 21 days for 4 courses according to their physicians and/or patients' choice. Patients may undergo surgery and/or further chemotherapy at the discretion of treating physician. Patients undergo blood sample collection at baseline and periodically during course 1 for pharmacokinetic studies.

Patients' quality of life is assessed by the FACT-O, the FACT-Ntx subscale, the IADL, and the Ability to Complete Social Activity questionnaires at baseline, prior to courses 1 and 3, and then 3-6 weeks after completion of course 4. Nutritional status, such as body mass index and weight loss, and comorbidity and hearing impairment are also assessed.

Other: pharmacological study
Correlative studies
Other Name: pharmacological studies
Other: questionnaire administration
Ancillary studies
Procedure: assessment of therapy complications
Undergo nutritional status, such as body mass index and weight loss, and comorbidity and hearing impairment assessments
Other: quality-of-life assessment
Ancillary studies
Other Name: quality of life assessment
Drug: carboplatin
Undergo chemotherapy
Other Names:
  • Carboplat
  • CBDCA
  • JM-8
  • Paraplat
  • Paraplatin
Drug: paclitaxel
Undergo chemotherapy
Other Names:
  • Anzatax
  • Asotax
  • TAX
  • Taxol
Biological: filgrastim
Undergo chemotherapy
Other Names:
  • G-CSF
  • Neupogen

Detailed Description:

PRIMARY OBJECTIVES:

l. To determine whether the score on Instrumental Activities of Daily Living (IADL) obtained prior to treatment is associated with the ability of patients to complete four cycles of chemotherapy without dose reduction or a more than 7-day delay.

II. To estimate by regimen the percentage of patients who are able to complete four cycles of chemotherapy regardless of dose reductions and delays.

III. To compare actual and calculated carboplatin area under the curve (AUC) in this patient population.

SECONDARY OBJECTIVES:

I. To describe the percentage of patients who are entered after primary surgery versus those entered to receive primary or neoadjuvant chemotherapy, the percentage of patients who are treated with each allowed regimen, and the percentage of patients who eventually receive surgery in the primary chemotherapy group.

II. To determine whether the need for assistance with IADLs at time of registration is associated with choice of chemotherapy regimen (in both primary chemotherapy and primary surgery patients).

III. To explore whether age, baseline scores on the geriatric measures (functional status, nutritional status, or co-morbidity) and quality-of-life (QOL) are correlated with likelihood of completing four courses of chemotherapy without dose reduction or a more than 7-day delay.

IV. To explore reasons for and timing of dose reductions and delays. V. To describe toxicities, pre-/post-chemotherapy QOL, and pre-/post-chemotherapy scores on geriatric measures in this patient population.

TERTIARY OBJECTIVES:

I. To explore potential relationships of carboplatin AUC, paclitaxel clearance, and paclitaxel time above a plasma concentration of 0.05 mcM to nadir neutrophil and platelet counts during course 1 of treatment.

II. To explore the association between baseline IADL and survival. III. To explore the association between IADL and the functional well-being (FWB) subscale in the Functional Assessment of Cancer Therapy - Ovary (FACT-O).

OUTLINE:

Patients receive chemotherapy comprising carboplatin, paclitaxel, and filgrastim (regimen 1) or carboplatin alone (regimen 2) every 21 days for 4 courses according to their physicians and/or patients' choice. Patients may undergo surgery and/or further chemotherapy at the discretion of treating physician. Patients undergo blood sample collection at baseline and periodically during course 1 for pharmacokinetic studies.

Patients' quality of life is assessed by the FACT-O, the Functional Assessment of Cancer Treatment - Neurotoxicity (FACT-Ntx subscale), the IADL, and the Ability to Complete Social Activity questionnaires at baseline, prior to courses 1 and 3, and then 3-6 weeks after completion of course 4. Nutritional status, such as body mass index and weight loss, and comorbidity and hearing impairment are also assessed.

  Eligibility

Ages Eligible for Study:   75 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population

Patients over 75 years old with ovarian, fallopian tube or primary peritoneal caner

Criteria

Inclusion Criteria:

  • Eligible patients must have a histologically or cytologically confirmed diagnosis of adenocarcinoma of the ovary, peritoneum, or fallopian tube either by surgery, biopsy, fine-needle aspiration (FNA), paracentesis, or thoracentesis; a diagnosis of a mucinous cancer must be made by biopsy only
  • International Federation of Gynecology and Obstetrics (FIGO) stage I, II, III, and IV are eligible
  • Patients must have received no previous treatment for this malignancy other than surgery
  • Patients must be entered within eight weeks of confirmation of disease diagnosis by surgery, biopsy, FNA, paracentesis or thoracentesis if there is no primary surgery, and within twelve weeks of primary or staging surgery if patient received primary surgery
  • Absolute neutrophil count (ANC) greater than or equal to 1,500/mcl
  • Platelets greater than or equal to 100,000/mcl
  • Bilirubin less than or equal upper limit of normal (ULN)
  • Creatinine less than or equal to 1.5 x ULN
  • Patients must have a Gynecologic Oncology Group (GOG) performance status of 0, 1, 2 or 3
  • Effective XX/XX/2014, only patients 75 years of age or older are eligible for enrollment; (04/23/2012) (08/12/2013)
  • Patients must have recovered from the effects of recent surgery
  • Patients must be free of active infection requiring antibiotics
  • Patients must have signed an approved informed consent and Health Insurance Portability and Accountability Act (HIPAA)
  • Patient and physician agree that they plan to conduct treatment according to Regimen 3
  • Patient can read and understand sufficient English to be able to respond to questions posed by the study instruments

Exclusion Criteria:

  • Patients who have received previous treatment for this malignancy other than surgery
  • Patients with other invasive malignancies whose previous cancer treatment contraindicates this protocol therapy
  • "Borderline tumors" (tumors of low malignant potential) by surgery or biopsy are excluded
  • Patients with medical conditions that in the opinion of the investigator render treatment on this protocol unsafe should be excluded
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT01366183

  Hide Study Locations
Locations
United States, Alabama
University of Alabama at Birmingham Recruiting
Birmingham, Alabama, United States, 35294
Contact: Larry C. Kilgore    865-544-9773      
Principal Investigator: Larry C. Kilgore         
United States, Arizona
Saint Joseph's Hospital and Medical Center Recruiting
Phoenix, Arizona, United States, 85013
Contact: John H. Farley    877-602-4111      
Principal Investigator: John H. Farley         
Gynecologic Oncology Group of Arizona Recruiting
Phoenix, Arizona, United States, 85012
Contact: Vivian E. von Gruenigen    330-379-3514    vongruev@summahealth.org   
Principal Investigator: Vivian E. von Gruenigen         
Mayo Clinic Hospital Active, not recruiting
Phoenix, Arizona, United States, 85054
Mayo Clinic in Arizona Recruiting
Scottsdale, Arizona, United States, 85259
Contact: Jamie N. Bakkum-Gamez    507-538-7623      
Principal Investigator: Jamie N. Bakkum-Gamez         
Arizona Cancer Center at University Medical Center North Recruiting
Tucson, Arizona, United States, 85719
Contact: Setsuko K. Chambers    520-626-9008      
Principal Investigator: Setsuko K. Chambers         
United States, California
John Muir Medical Center-Concord Campus Recruiting
Concord, California, United States, 94520
Contact: Babak Edraki    925-674-2580      
Principal Investigator: Babak Edraki         
UC San Diego Moores Cancer Center Recruiting
LA Jolla, California, United States, 92093
Contact: Michael T. McHale    858-822-5354    cancercto@ucsd.edu   
Principal Investigator: Michael T. McHale         
Palo Alto Medical Foundation-Gynecologic Oncology Recruiting
Mountain View, California, United States, 94040
Contact: Albert L. Pisani    650-934-7000      
Principal Investigator: Albert L. Pisani         
Saint Joseph Hospital - Orange Recruiting
Orange, California, United States, 92868
Contact: Michael L. Berman    877-827-8839    ucstudy@uci.edu   
Principal Investigator: Michael L. Berman         
University of California Medical Center At Irvine-Orange Campus Recruiting
Orange, California, United States, 92868
Contact: Krishnansu S. Tewari    714-456-6191    awallick@uci.edu   
Principal Investigator: Krishnansu S. Tewari         
UCSF-Mount Zion Recruiting
San Francisco, California, United States, 94115
Contact: John K. Chan    415-600-1182    SchmidtJ@cpmcri.org   
Principal Investigator: John K. Chan         
Stanford University Hospitals and Clinics Recruiting
Stanford, California, United States, 94305
Contact: Jonathan S. Berek    650-498-7061    clinicaltrials@med.stanford.edu   
Principal Investigator: Jonathan S. Berek         
Olive View-University of California Los Angeles Medical Center Recruiting
Sylmar, California, United States, 91342
Contact: Christine H. Holschneider    888-798-0719      
Principal Investigator: Christine H. Holschneider         
United States, Colorado
Rocky Mountain Gynecologic Oncology PC Active, not recruiting
Englewood, Colorado, United States, 80110
United States, Connecticut
Danbury Hospital Active, not recruiting
Danbury, Connecticut, United States, 06810
Hartford Hospital Recruiting
Hartford, Connecticut, United States, 06102
Contact: James S. Hoffman    860-224-5660      
Principal Investigator: James S. Hoffman         
Saint Francis Hospital and Medical Center Recruiting
Hartford, Connecticut, United States, 06105
Contact: Philip J. Stella    734-712-3456      
Principal Investigator: Philip J. Stella         
Middlesex Hospital Recruiting
Middletown, Connecticut, United States, 06457
Contact: Susanna Hong    860-358-2058      
Principal Investigator: Susanna Hong         
The Hospital of Central Connecticut Recruiting
New Britain, Connecticut, United States, 06050
Contact: James S. Hoffman    860-224-5660      
Principal Investigator: James S. Hoffman         
Yale University Active, not recruiting
New Haven, Connecticut, United States, 06520
Stamford Hospital/Bennett Cancer Center Terminated
Stamford, Connecticut, United States, 06904
United States, Delaware
Beebe Medical Center Recruiting
Lewes, Delaware, United States, 19958
Contact: Mark E. Borowsky    302-733-6227      
Principal Investigator: Mark E. Borowsky         
Christiana Care Health System-Christiana Hospital Recruiting
Newark, Delaware, United States, 19718
Contact: Mark E. Borowsky    302-733-6227      
Principal Investigator: Mark E. Borowsky         
United States, Florida
Holy Cross Hospital Recruiting
Fort Lauderdale, Florida, United States, 33308
Contact: Michael A. Schwartz    305-674-2625    info@msccop.com   
Principal Investigator: Michael A. Schwartz         
Florida Gynecologic Oncology Recruiting
Fort Myers, Florida, United States, 33905
Contact: Edward C. Grendys    800-874-7502      
Principal Investigator: Edward C. Grendys         
Jupiter Medical Center Recruiting
Jupiter, Florida, United States, 33458
Contact: Michael A. Schwartz    305-674-2625    info@msccop.com   
Principal Investigator: Michael A. Schwartz         
Mercy Hospital Active, not recruiting
Miami, Florida, United States, 33133
Mount Sinai Medical Center CCOP Recruiting
Miami Beach, Florida, United States, 33140
Contact: Michael A. Schwartz    305-674-2625    info@msccop.com   
Principal Investigator: Michael A. Schwartz         
Sarasota Memorial Hospital Recruiting
Sarasota, Florida, United States, 34239
Contact: James V. Fiorica    941-917-2225      
Principal Investigator: James V. Fiorica         
H. Lee Moffitt Cancer Center and Research Institute Recruiting
Tampa, Florida, United States, 33612
Contact: Robert M. Wenham    800-456-7121    canceranswers@moffitt.org   
Principal Investigator: Robert M. Wenham         
United States, Georgia
Georgia Regents University Recruiting
Augusta, Georgia, United States, 30912
Contact: Sharad A. Ghamande    706-721-1663    cancer@georgiahealth.edu   
Principal Investigator: Sharad A. Ghamande         
John B Amos Cancer Center Recruiting
Columbus, Georgia, United States, 31904
Contact: Gregory P. Sfakianos    706-660-6404      
Principal Investigator: Gregory P. Sfakianos         
Dekalb Medical Center Recruiting
Decatur, Georgia, United States, 30033
Contact: Jayanthi Srinivasiah    404-501-3279      
Principal Investigator: Jayanthi Srinivasiah         
Northeast Georgia Medical Center Recruiting
Gainesville, Georgia, United States, 30501
Contact: Andrew E. Green    770-219-8800    cancerpatient.navigator@nghs.com   
Principal Investigator: Andrew E. Green         
Saint Joseph's-Candler Health System Recruiting
Savannah, Georgia, United States, 31405
Contact: William E. Richards    800-622-6877    uchealthnews@uc.edu   
Principal Investigator: William E. Richards         
Memorial Health University Medical Center Recruiting
Savannah, Georgia, United States, 31403
Contact: James J. Burke    912-350-8568      
Principal Investigator: James J. Burke         
United States, Idaho
Saint Alphonsus Regional Medical Center Recruiting
Boise, Idaho, United States, 83706
Contact: Philip J. Stella    734-712-3456      
Principal Investigator: Philip J. Stella         
United States, Illinois
Northwestern University Active, not recruiting
Chicago, Illinois, United States, 60611
University of Chicago Active, not recruiting
Chicago, Illinois, United States, 60637
Weiss Memorial Hospital Terminated
Chicago, Illinois, United States, 60640
Sudarshan K Sharma MD Limted-Gynecologic Oncology Recruiting
Hinsdale, Illinois, United States, 60521
Contact: Sudarshan K. Sharma    630-856-6757      
Principal Investigator: Sudarshan K. Sharma         
Good Samaritan Regional Health Center Recruiting
Mount Vernon, Illinois, United States, 62864
Contact: Jay W. Carlson    888-244-6061    sherrijr@iora.org   
Principal Investigator: Jay W. Carlson         
West Suburban Medical Center Terminated
River Forest, Illinois, United States, 60305
Central DuPage Hospital Cancer Center Recruiting
Warrenville, Illinois, United States, 60555
Contact: Barbara M. Buttin    630-352-5300    cancer@northwestern.edu   
Principal Investigator: Barbara M. Buttin         
United States, Indiana
Saint Francis Hospital and Health Centers Recruiting
Beech Grove, Indiana, United States, 46107
Contact: Howard M. Gross    765-983-3000      
Principal Investigator: Howard M. Gross         
Elkhart Clinic Recruiting
Elkhart, Indiana, United States, 46514-2098
Contact: Michael W. Method    574-237-1328      
Principal Investigator: Michael W. Method         
Michiana Hematology Oncology PC-Elkhart Recruiting
Elkhart, Indiana, United States, 46514
Contact: Michael W. Method    574-237-1328      
Principal Investigator: Michael W. Method         
Elkhart General Hospital Recruiting
Elkhart, Indiana, United States, 46515
Contact: Michael W. Method    574-237-1328      
Principal Investigator: Michael W. Method         
Franciscan Saint Francis Health-Indianapolis Active, not recruiting
Indianapolis, Indiana, United States, 46237
Saint Vincent Oncology Center Recruiting
Indianapolis, Indiana, United States, 46260
Contact: Gregory P. Sutton    317-338-2194      
Principal Investigator: Gregory P. Sutton         
Community Howard Regional Health Recruiting
Kokomo, Indiana, United States, 46904
Contact: Michael W. Method    574-237-1328      
Principal Investigator: Michael W. Method         
Indiana University Health La Porte Hospital Recruiting
La Porte, Indiana, United States, 46350
Contact: Michael W. Method    574-237-1328      
Principal Investigator: Michael W. Method         
Michiana Hematology Oncology PC-Mishawaka Recruiting
Mishawaka, Indiana, United States, 46545-1470
Contact: Michael W. Method    574-237-1328      
Principal Investigator: Michael W. Method         
Cancer Care Partners LLC Terminated
Mishawaka, Indiana, United States, 46545
Saint Joseph Regional Medical Center-Mishawaka Recruiting
Mishawaka, Indiana, United States, 46545-1470
Contact: Michael W. Method    574-237-1328      
Principal Investigator: Michael W. Method         
Michiana Hematology Oncology PC-Plymouth Recruiting
Plymouth, Indiana, United States, 46563
Contact: Michael W. Method    574-237-1328      
Principal Investigator: Michael W. Method         
Reid Hospital and Health Care Services Recruiting
Richmond, Indiana, United States, 47374
Contact: Howard M. Gross    765-983-3000      
Principal Investigator: Howard M. Gross         
Michiana Hematology Oncology PC-South Bend Recruiting
South Bend, Indiana, United States, 46601
Contact: Michael W. Method    574-237-1328      
Principal Investigator: Michael W. Method         
Northern Indiana Cancer Research Consortium Recruiting
South Bend, Indiana, United States, 46628
Contact: Michael W. Method    574-237-1328      
Principal Investigator: Michael W. Method         
Memorial Hospital of South Bend Terminated
South Bend, Indiana, United States, 46601
South Bend Clinic Recruiting
South Bend, Indiana, United States, 46617
Contact: Michael W. Method    574-237-1328      
Principal Investigator: Michael W. Method         
Michiana Hematology Oncology-PC Westville Recruiting
Westville, Indiana, United States, 46391
Contact: Michael W. Method    574-237-1328      
Principal Investigator: Michael W. Method         
United States, Iowa
McFarland Clinic PC-William R Bliss Cancer Center Recruiting
Ames, Iowa, United States, 50010
Contact: Joseph J. Merchant    515-239-2621      
Principal Investigator: Joseph J. Merchant         
Cedar Rapids Oncology Association Terminated
Cedar Rapids, Iowa, United States, 52403
Mercy Hospital Terminated
Cedar Rapids, Iowa, United States, 52403
Oncology Associates at Mercy Medical Center Terminated
Cedar Rapids, Iowa, United States, 52403
Mercy Cancer Center-West Lakes Recruiting
Clive, Iowa, United States, 50325
Contact: Robert J. Behrens    888-244-6061    sherrijr@iora.org   
Principal Investigator: Robert J. Behrens         
Medical Oncology and Hematology Associates-West Des Moines Recruiting
Clive, Iowa, United States, 50325
Contact: Robert J. Behrens    888-244-6061    sherrijr@iora.org   
Principal Investigator: Robert J. Behrens         
Medical Oncology and Hematology Associates-Laurel Recruiting
Des Moines, Iowa, United States, 50314
Contact: Robert J. Behrens    888-244-6061    sherrijr@iora.org   
Principal Investigator: Robert J. Behrens         
Medical Oncology and Hematology Associates-Des Moines Recruiting
Des Moines, Iowa, United States, 50309
Contact: Robert J. Behrens    888-244-6061    sherrijr@iora.org   
Principal Investigator: Robert J. Behrens         
Iowa Methodist Medical Center Recruiting
Des Moines, Iowa, United States, 50309
Contact: Robert J. Behrens    888-244-6061    sherrijr@iora.org   
Principal Investigator: Robert J. Behrens         
Iowa Lutheran Hospital Recruiting
Des Moines, Iowa, United States, 50316
Contact: Robert J. Behrens    888-244-6061    sherrijr@iora.org   
Principal Investigator: Robert J. Behrens         
Mercy Medical Center - Des Moines Recruiting
Des Moines, Iowa, United States, 50314
Contact: Robert J. Behrens    888-244-6061    sherrijr@iora.org   
Principal Investigator: Robert J. Behrens         
Iowa Oncology Research Association CCOP Recruiting
Des Moines, Iowa, United States, 50309
Contact: Robert J. Behrens    888-244-6061    sherrijr@iora.org   
Principal Investigator: Robert J. Behrens         
University of Iowa Hospitals and Clinics Recruiting
Iowa City, Iowa, United States, 52242
Contact: David P. Bender    800-237-1225      
Principal Investigator: David P. Bender         
Mercy Medical Center-Sioux City Recruiting
Sioux City, Iowa, United States, 51104
Contact: Donald B. Wender    712-252-0088      
Principal Investigator: Donald B. Wender         
Saint Luke's Regional Medical Center Recruiting
Sioux City, Iowa, United States, 51104
Contact: Donald B. Wender    712-252-0088      
Principal Investigator: Donald B. Wender         
Siouxland Hematology Oncology Associates Recruiting
Sioux City, Iowa, United States, 51101
Contact: Donald B. Wender    712-252-0088      
Principal Investigator: Donald B. Wender         
Mercy Medical Center-West Lakes Recruiting
West Des Moines, Iowa, United States, 50266
Contact: Robert J. Behrens    888-244-6061    sherrijr@iora.org   
Principal Investigator: Robert J. Behrens         
Methodist West Hospital Recruiting
West Des Moines, Iowa, United States, 50266-7700
Contact: Robert J. Behrens    888-244-6061    sherrijr@iora.org   
Principal Investigator: Robert J. Behrens         
United States, Kansas
Cancer Center of Kansas - Chanute Recruiting
Chanute, Kansas, United States, 66720
Contact: Shaker R. Dakhil    316-262-4467      
Principal Investigator: Shaker R. Dakhil         
Cancer Center of Kansas - Dodge City Recruiting
Dodge City, Kansas, United States, 67801
Contact: Shaker R. Dakhil    316-262-4467      
Principal Investigator: Shaker R. Dakhil         
Cancer Center of Kansas - El Dorado Recruiting
El Dorado, Kansas, United States, 67042
Contact: Shaker R. Dakhil    316-262-4467      
Principal Investigator: Shaker R. Dakhil         
Cancer Center of Kansas - Fort Scott Recruiting
Fort Scott, Kansas, United States, 66701
Contact: Shaker R. Dakhil    316-262-4467      
Principal Investigator: Shaker R. Dakhil         
Cancer Center of Kansas-Independence Recruiting
Independence, Kansas, United States, 67301
Contact: Shaker R. Dakhil    316-262-4467      
Principal Investigator: Shaker R. Dakhil         
Providence Medical Center Terminated
Kansas City, Kansas, United States, 66112
Cancer Center of Kansas-Kingman Recruiting
Kingman, Kansas, United States, 67068
Contact: Shaker R. Dakhil    316-262-4467      
Principal Investigator: Shaker R. Dakhil         
Lawrence Memorial Hospital Recruiting
Lawrence, Kansas, United States, 66044
Contact: Shaker R. Dakhil    316-262-4467      
Principal Investigator: Shaker R. Dakhil         
Cancer Center of Kansas-Liberal Recruiting
Liberal, Kansas, United States, 67901
Contact: Shaker R. Dakhil    316-262-4467      
Principal Investigator: Shaker R. Dakhil         
Cancer Center of Kansas-Manhattan Recruiting
Manhattan, Kansas, United States, 66502
Contact: Shaker R. Dakhil    316-262-4467      
Principal Investigator: Shaker R. Dakhil         
Cancer Center of Kansas - McPherson Recruiting
McPherson, Kansas, United States, 67460
Contact: Shaker R. Dakhil    316-262-4467      
Principal Investigator: Shaker R. Dakhil         
Cancer Center of Kansas - Newton Recruiting
Newton, Kansas, United States, 67114
Contact: Shaker R. Dakhil    316-262-4467      
Principal Investigator: Shaker R. Dakhil         
Saint Luke's South Hospital Recruiting
Overland Park, Kansas, United States, 66213
Contact: Rakesh Gaur    913-948-5588    aroland@kccop.org   
Principal Investigator: Rakesh Gaur         
Menorah Medical Center Recruiting
Overland Park, Kansas, United States, 66209
Contact: Rakesh Gaur    913-948-5588    aroland@kccop.org   
Principal Investigator: Rakesh Gaur         
Cancer Center of Kansas - Parsons Recruiting
Parsons, Kansas, United States, 67357
Contact: Shaker R. Dakhil    316-262-4467      
Principal Investigator: Shaker R. Dakhil         
Kansas City CCOP Recruiting
Prairie Village, Kansas, United States, 66208
Contact: Rakesh Gaur    913-948-5588    aroland@kccop.org   
Principal Investigator: Rakesh Gaur         
Cancer Center of Kansas - Pratt Recruiting
Pratt, Kansas, United States, 67124
Contact: Shaker R. Dakhil    316-262-4467      
Principal Investigator: Shaker R. Dakhil         
Cancer Center of Kansas - Salina Recruiting
Salina, Kansas, United States, 67401
Contact: Shaker R. Dakhil    316-262-4467      
Principal Investigator: Shaker R. Dakhil         
Stormont-Vail Regional Health Center Terminated
Topeka, Kansas, United States, 66604
Cancer Center of Kansas - Wellington Recruiting
Wellington, Kansas, United States, 67152
Contact: Shaker R. Dakhil    316-262-4467      
Principal Investigator: Shaker R. Dakhil         
Cancer Center of Kansas-Wichita Medical Arts Tower Recruiting
Wichita, Kansas, United States, 67208
Contact: Shaker R. Dakhil    316-262-4467      
Principal Investigator: Shaker R. Dakhil         
Cancer Center of Kansas - Main Office Recruiting
Wichita, Kansas, United States, 67214
Contact: Shaker R. Dakhil    316-262-4467      
Principal Investigator: Shaker R. Dakhil         
Associates In Womens Health Recruiting
Wichita, Kansas, United States, 67208
Contact: Shaker R. Dakhil    316-262-4467      
Principal Investigator: Shaker R. Dakhil         
Via Christi Regional Medical Center Recruiting
Wichita, Kansas, United States, 67214
Contact: Shaker R. Dakhil    316-262-4467      
Principal Investigator: Shaker R. Dakhil         
Wichita CCOP Recruiting
Wichita, Kansas, United States, 67214
Contact: Shaker R. Dakhil    316-262-4467      
Principal Investigator: Shaker R. Dakhil         
Cancer Center of Kansas - Winfield Recruiting
Winfield, Kansas, United States, 67156
Contact: Shaker R. Dakhil    316-262-4467      
Principal Investigator: Shaker R. Dakhil         
United States, Kentucky
Saint Elizabeth Medical Center South Recruiting
Edgewood, Kentucky, United States, 41017
Contact: Jack B. Basil    859-301-5473    darla.hehman@stelizabeth.com   
Principal Investigator: Jack B. Basil         
Baptist Health Lexington Recruiting
Lexington, Kentucky, United States, 40503
Contact: Hope M. Cottrill    859-260-6425      
Principal Investigator: Hope M. Cottrill         
Norton Health Care Pavilion - Downtown Recruiting
Louisville, Kentucky, United States, 40202
Contact: Mary E. Gordinier    502-629-2500      
Principal Investigator: Mary E. Gordinier         
United States, Louisiana
Woman's Hospital Recruiting
Baton Rouge, Louisiana, United States, 70817
Contact: Giles Fort    225-215-1353    clinicalreserach@marybird.com   
Principal Investigator: Giles Fort         
Ochsner Medical Center Recruiting
New Orleans, Louisiana, United States, 70121
Contact: Richard C. Kline    888-562-4763      
Principal Investigator: Richard C. Kline         
Tulane University Health Sciences Center Active, not recruiting
New Orleans, Louisiana, United States, 70112
United States, Maine
Harold Alfond Center for Cancer Care Recruiting
Augusta, Maine, United States, 04330
Contact: Thomas H. Openshaw    207-973-4274      
Principal Investigator: Thomas H. Openshaw         
Eastern Maine Medical Center Recruiting
Bangor, Maine, United States, 04401
Contact: Thomas H. Openshaw    207-973-4274      
Principal Investigator: Thomas H. Openshaw         
Maine Medical Center-Bramhall Campus Recruiting
Portland, Maine, United States, 04102
Contact: Christopher J. Darus    207-885-7565      
Principal Investigator: Christopher J. Darus         
United States, Maryland
University of Maryland Greenebaum Cancer Center Recruiting
Baltimore, Maryland, United States, 21201-1595
Contact: Sarah M. Temkin    800-888-8823      
Principal Investigator: Sarah M. Temkin         
Greater Baltimore Medical Center Recruiting
Baltimore, Maryland, United States, 21204
Contact: Paul Celano    443-849-3706      
Principal Investigator: Paul Celano         
Union Hospital of Cecil County Terminated
Elkton MD, Maryland, United States, 21921
United States, Massachusetts
Boston Medical Center Active, not recruiting
Boston, Massachusetts, United States, 02118
Lahey Hospital and Medical Center Recruiting
Burlington, Massachusetts, United States, 01805
Contact: Corrine L. Zarwan    781-744-8027      
Principal Investigator: Corrine L. Zarwan         
Beth Israel Deaconess Hospital-Plymouth Terminated
Plymouth, Massachusetts, United States, 02360
University of Massachusetts Memorial Health Care Active, not recruiting
Worcester, Massachusetts, United States, 01605
United States, Michigan
Michigan Cancer Research Consortium Community Clinical Oncology Program Recruiting
Ann Arbor, Michigan, United States, 48106
Contact: Philip J. Stella    734-712-3456      
Principal Investigator: Philip J. Stella         
Saint Joseph Mercy Hospital Recruiting
Ann Arbor, Michigan, United States, 48106-0995
Contact: Philip J. Stella    734-712-3456      
Principal Investigator: Philip J. Stella         
Oakwood Hospital Recruiting
Dearborn, Michigan, United States, 48124
Contact: Philip J. Stella    734-712-3456      
Principal Investigator: Philip J. Stella         
Wayne State University-Karmanos Cancer Institute Recruiting
Detroit, Michigan, United States, 48201
Contact: Robert T. Morris    313-576-9363      
Principal Investigator: Robert T. Morris         
Henry Ford Hospital Recruiting
Detroit, Michigan, United States, 48202
Contact: Thomas E. Buekers    313-916-1784      
Principal Investigator: Thomas E. Buekers         
Saint John Hospital and Medical Center Recruiting
Detroit, Michigan, United States, 48236
Contact: Philip J. Stella    734-712-3456      
Principal Investigator: Philip J. Stella         
Green Bay Oncology - Escanaba Recruiting
Escanaba, Michigan, United States, 49431
Contact: Jonathan E. Tammela    920-433-8889      
Principal Investigator: Jonathan E. Tammela         
Genesys Regional Medical Center-West Flint Campus Recruiting
Flint, Michigan, United States, 48532
Contact: Philip J. Stella    734-712-3456      
Principal Investigator: Philip J. Stella         
Genesys Hurley Cancer Institute Recruiting
Flint, Michigan, United States, 48503
Contact: Philip J. Stella    734-712-3456      
Principal Investigator: Philip J. Stella         
Hurley Medical Center Recruiting
Flint, Michigan, United States, 48502
Contact: Philip J. Stella    734-712-3456      
Principal Investigator: Philip J. Stella         
Genesys Regional Medical Center Terminated
Grand Blanc, Michigan, United States, 48439
Green Bay Oncology - Iron Mountain Recruiting
Iron Mountain, Michigan, United States, 49801
Contact: Jonathan E. Tammela    920-433-8889      
Principal Investigator: Jonathan E. Tammela         
Allegiance Health Recruiting
Jackson, Michigan, United States, 49201
Contact: Philip J. Stella    734-712-3456      
Principal Investigator: Philip J. Stella         
Borgess Medical Center Recruiting
Kalamazoo, Michigan, United States, 49001
Contact: Raymond S. Lord    269-373-7458      
Principal Investigator: Raymond S. Lord         
West Michigan Cancer Center Recruiting
Kalamazoo, Michigan, United States, 49007
Contact: Raymond S. Lord    269-373-7458      
Principal Investigator: Raymond S. Lord         
Bronson Methodist Hospital Recruiting
Kalamazoo, Michigan, United States, 49007
Contact: Raymond S. Lord    269-373-7458      
Principal Investigator: Raymond S. Lord         
Sparrow Hospital Recruiting
Lansing, Michigan, United States, 48912
Contact: Philip J. Stella    734-712-3456      
Principal Investigator: Philip J. Stella         
Saint Mary Mercy Hospital Recruiting
Livonia, Michigan, United States, 48154
Contact: Philip J. Stella    734-712-3456      
Principal Investigator: Philip J. Stella         
Saint Joseph Mercy Oakland Recruiting
Pontiac, Michigan, United States, 48341-2985
Contact: Philip J. Stella    734-712-3456      
Principal Investigator: Philip J. Stella         
Saint Joseph Mercy Port Huron Recruiting
Port Huron, Michigan, United States, 48060
Contact: Philip J. Stella    734-712-3456      
Principal Investigator: Philip J. Stella         
William Beaumont Hospital-Royal Oak Recruiting
Royal Oak, Michigan, United States, 48073
Contact: Jayson B. Field    248-551-7695      
Principal Investigator: Jayson B. Field         
Saint Mary's of Michigan Recruiting
Saginaw, Michigan, United States, 48601
Contact: Philip J. Stella    734-712-3456      
Principal Investigator: Philip J. Stella         
Marie Yeager Cancer Center Recruiting
Saint Joseph, Michigan, United States, 49085
Contact: Michael W. Method    574-237-1328      
Principal Investigator: Michael W. Method         
Providence Hospital Recruiting
Southfield, Michigan, United States, 48075
Contact: Vinay K. Malviya    248-849-5337    jaswinder.grewal@stjohn.org   
Principal Investigator: Vinay K. Malviya         
Lakeland Hospital Recruiting
St. Joseph, Michigan, United States, 49085
Contact: Michael W. Method    574-237-1328      
Principal Investigator: Michael W. Method         
William Beaumont Hospital - Troy Active, not recruiting
Troy, Michigan, United States, 48098
Saint John Macomb-Oakland Hospital Recruiting
Warren, Michigan, United States, 48093
Contact: Philip J. Stella    734-712-3456      
Principal Investigator: Philip J. Stella         
United States, Minnesota
Sanford Clinic North-Bemidgi Recruiting
Bemidji, Minnesota, United States, 56601
Contact: Maria C. Bell    218-333-5000      
Principal Investigator: Maria C. Bell         
University of Minnesota Medical Center-Fairview Recruiting
Minneapolis, Minnesota, United States, 55455
Contact: Peter A. Argenta    612-624-2620      
Principal Investigator: Peter A. Argenta         
Mayo Clinic Recruiting
Rochester, Minnesota, United States, 55905
Contact: Jamie N. Bakkum-Gamez    507-538-7623      
Principal Investigator: Jamie N. Bakkum-Gamez         
Park Nicollet Clinic - Saint Louis Park Active, not recruiting
Saint Louis Park, Minnesota, United States, 55416
Park Nicollet Frauenshuh Cancer Center Terminated
Saint Louis Park, Minnesota, United States, 55426
United States, Missouri
Saint Luke's Hospital of Kansas City Recruiting
Kansas City, Missouri, United States, 64111
Contact: Rakesh Gaur    913-948-5588    aroland@kccop.org   
Principal Investigator: Rakesh Gaur         
Heartland Hematology and Oncology Associates Incorporated Recruiting
Kansas City, Missouri, United States, 64118
Contact: Rakesh Gaur    913-948-5588    aroland@kccop.org   
Principal Investigator: Rakesh Gaur         
North Kansas City Hospital Terminated
Kansas City, Missouri, United States, 64116
Saint Luke's Cancer Institute Terminated
Kansas City, Missouri, United States, 64111
Research Medical Center Recruiting
Kansas City, Missouri, United States, 64132
Contact: Rakesh Gaur    913-948-5588    aroland@kccop.org   
Principal Investigator: Rakesh Gaur         
Saint Luke's East - Lee's Summit Recruiting
Lee's Summit, Missouri, United States, 64086
Contact: Rakesh Gaur    913-948-5588    aroland@kccop.org   
Principal Investigator: Rakesh Gaur         
Liberty Radiation Oncology Clinic Recruiting
Liberty, Missouri, United States, 64068
Contact: Rakesh Gaur    913-948-5588    aroland@kccop.org   
Principal Investigator: Rakesh Gaur         
Saint John's Clinic-Rolla-Cancer and Hematology Active, not recruiting
Rolla, Missouri, United States, 65401
Heartland Regional Medical Center Recruiting
Saint Joseph, Missouri, United States, 64506
Contact: Rakesh Gaur    913-948-5588    aroland@kccop.org   
Principal Investigator: Rakesh Gaur         
Saint Joseph Oncology Inc Recruiting
Saint Joseph, Missouri, United States, 64507
Contact: Rakesh Gaur    913-948-5588    aroland@kccop.org   
Principal Investigator: Rakesh Gaur         
Washington University School of Medicine Recruiting
Saint Louis, Missouri, United States, 63110
Contact: David G. Mutch    800-600-3606    info@ccadmin.wustl.edu   
Principal Investigator: David G. Mutch         
CoxHealth South Hospital Recruiting
Springfield, Missouri, United States, 65807
Contact: Jay W. Carlson    888-244-6061    sherrijr@iora.org   
Principal Investigator: Jay W. Carlson         
Mercy Hospital Springfield Recruiting
Springfield, Missouri, United States, 65804
Contact: Jay W. Carlson    888-244-6061    sherrijr@iora.org   
Principal Investigator: Jay W. Carlson         
Ozark Health Ventures LLC dba Cancer Research for The Ozarks Springfield Active, not recruiting
Springfield, Missouri, United States, 65802
United States, Montana
Billings Clinic Recruiting
Billings, Montana, United States, 59107-7000
Contact: Benjamin T. Marchello    800-648-6274      
Principal Investigator: Benjamin T. Marchello         
Montana Cancer Consortium CCOP Recruiting
Billings, Montana, United States, 59101
Contact: Benjamin T. Marchello    800-648-6274      
Principal Investigator: Benjamin T. Marchello         
Saint Vincent Healthcare Recruiting
Billings, Montana, United States, 59101
Contact: Benjamin T. Marchello    800-648-6274      
Principal Investigator: Benjamin T. Marchello         
Hematology-Oncology Centers of the Northern Rockies PC Terminated
Billings, Montana, United States, 59102
Bozeman Deaconess Hospital Recruiting
Bozeman, Montana, United States, 59715
Contact: Benjamin T. Marchello    800-648-6274      
Principal Investigator: Benjamin T. Marchello         
Bozeman Deaconess Cancer Center Terminated
Bozeman, Montana, United States, 59715
Saint James Community Hospital and Cancer Treatment Center Recruiting
Butte, Montana, United States, 59701
Contact: Benjamin T. Marchello    800-648-6274      
Principal Investigator: Benjamin T. Marchello         
Benefis Healthcare- Sletten Cancer Institute Recruiting
Great Falls, Montana, United States, 59405
Contact: Benjamin T. Marchello    800-648-6274      
Principal Investigator: Benjamin T. Marchello         
Great Falls Clinic Terminated
Great Falls, Montana, United States, 59405
Northern Montana Hospital Terminated
Havre, Montana, United States, 59501
Saint Peter's Community Hospital Recruiting
Helena, Montana, United States, 59601
Contact: Benjamin T. Marchello    800-648-6274      
Principal Investigator: Benjamin T. Marchello         
Glacier Oncology PLLC Terminated
Kalispell, Montana, United States, 59901
Kalispell Regional Medical Center Active, not recruiting
Kalispell, Montana, United States, 59901
Kalispell Medical Oncology Terminated
Kalispell, Montana, United States, 59901
Saint Patrick Hospital - Community Hospital Recruiting
Missoula, Montana, United States, 59802
Contact: Benjamin T. Marchello    800-648-6274      
Principal Investigator: Benjamin T. Marchello         
Montana Cancer Specialists Active, not recruiting
Missoula, Montana, United States, 59802
United States, Nebraska
Good Samaritan Hospital Recruiting
Kearney, Nebraska, United States, 68847
Contact: George K. Bascom    308-865-7963      
Principal Investigator: George K. Bascom         
Nebraska Methodist Hospital Recruiting
Omaha, Nebraska, United States, 68114
Contact: Peter C. Morris    402-354-7939    kathryn.bartz@nmhs.org   
Principal Investigator: Peter C. Morris         
United States, Nevada
Women's Cancer Center of Nevada Recruiting
Las Vegas, Nevada, United States, 89169
Contact: Nicola M. Spirtos    702-851-4672      
Principal Investigator: Nicola M. Spirtos         
United States, New Jersey
Cooper Hospital University Medical Center Recruiting
Camden, New Jersey, United States, 08103
Contact: David P. Warshal    856-325-6757      
Principal Investigator: David P. Warshal         
Hackensack University Medical Center Recruiting
Hackensack, New Jersey, United States, 07601
Contact: Donna T. McNamara    201-996-2879      
Principal Investigator: Donna T. McNamara         
Hackensack University Medical CCOP Terminated
Hackensack, New Jersey, United States, 07601
Fox Chase Cancer Center at Virtua Memorial Hospital of Burlington County Recruiting
Mount Holly, New Jersey, United States, 08060
Contact: Randolph B. Deger    888-847-8823      
Principal Investigator: Randolph B. Deger         
UMDNJ - New Jersey Medical School Recruiting
Newark, New Jersey, United States, 07103
Contact: Bernadette M. Cracchiolo    732-235-8675      
Principal Investigator: Bernadette M. Cracchiolo         
Virtua West Jersey Hospital Voorhees Recruiting
Voorhees, New Jersey, United States, 08043
Contact: Randolph B. Deger    888-847-8823      
Principal Investigator: Randolph B. Deger         
United States, New Mexico
Southwest Gynecologic Oncology Associates Inc Recruiting
Albuquerque, New Mexico, United States, 87106
Contact: Teresa L. Rutledge    505-272-6972      
Principal Investigator: Teresa L. Rutledge         
University of New Mexico Recruiting
Albuquerque, New Mexico, United States, 87106
Contact: Teresa L. Rutledge    505-272-6972      
Principal Investigator: Teresa L. Rutledge         
United States, New York
Women's Cancer Care Associates LLC Recruiting
Albany, New York, United States, 12208
Contact: Thomas P. Morrissey    518-458-1390      
Principal Investigator: Thomas P. Morrissey         
State University of New York Downstate Medical Center Active, not recruiting
Brooklyn, New York, United States, 11203
Roswell Park Cancer Institute Recruiting
Buffalo, New York, United States, 14263
Contact: Shashikant B. Lele    877-275-7724      
Principal Investigator: Shashikant B. Lele         
Glens Falls Hospital Terminated
Glens Falls, New York, United States, 12801
Monter Cancer Center Recruiting
Lake Success, New York, United States, 11042
Contact: Veena S. John    516-562-3467      
Principal Investigator: Veena S. John         
North Shore University Hospital Recruiting
Manhasset, New York, United States, 11030
Contact: Veena S. John    516-562-3467      
Principal Investigator: Veena S. John         
Long Island Jewish Medical Center Recruiting
New Hyde Park, New York, United States, 11040
Contact: Veena S. John    516-562-3467      
Principal Investigator: Veena S. John         
Memorial Sloan-Kettering Cancer Center Recruiting
New York, New York, United States, 10065
Contact: William P. Tew    212-639-7202      
Principal Investigator: William P. Tew         
Columbia University Medical Center Active, not recruiting
New York, New York, United States, 10032
New York University Langone Medical Center Recruiting
New York, New York, United States, 10016
Contact: Stephanie V. Blank    212-263-4434    prmc.coordinator@nyumc.org   
Principal Investigator: Stephanie V. Blank         
Stony Brook University Medical Center Recruiting
Stony Brook, New York, United States, 11794
Contact: Michael L. Pearl    800-862-2215      
Principal Investigator: Michael L. Pearl         
State University of New York Upstate Medical University Recruiting
Syracuse, New York, United States, 13210
Contact: Mary J. Cunningham    315-464-5476      
Principal Investigator: Mary J. Cunningham         
United States, North Carolina
Cone Health Alamance Regional Medical Center Recruiting
Burlington, North Carolina, United States, 27216
Contact: Janak K. Choksi    336-538-7725      
Principal Investigator: Janak K. Choksi         
University of North Carolina Recruiting
Chapel Hill, North Carolina, United States, 27599
Contact: Linda Van Le    877-668-0683    cancerclinicaltrials@med.unc.edu   
Principal Investigator: Linda Van Le         
Carolinas Medical Center Recruiting
Charlotte, North Carolina, United States, 28203
Contact: Robert V. Higgins    704-355-2884      
Principal Investigator: Robert V. Higgins         
Novant Health Presbyterian Medical Center Recruiting
Charlotte, North Carolina, United States, 28204
Contact: John M. McDonald    704-384-5369      
Principal Investigator: John M. McDonald         
Carolinas Medical Center - Northeast Recruiting
Concord, North Carolina, United States, 28025
Contact: Brigitte E. Miller    704-403-1520      
Principal Investigator: Brigitte E. Miller         
Duke University Medical Center Recruiting
Durham, North Carolina, United States, 27710
Contact: Angeles A. Secord    888-275-3853      
Principal Investigator: Angeles A. Secord         
Wayne Memorial Hospital Recruiting
Goldsboro, North Carolina, United States, 27534
Contact: James N. Atkins    919-580-0000      
Principal Investigator: James N. Atkins         
Duke Raleigh Hospital Recruiting
Raleigh, North Carolina, United States, 27609
Contact: Angeles A. Secord    888-275-3853      
Principal Investigator: Angeles A. Secord         
Wake Forest University Health Sciences Recruiting
Winston-Salem, North Carolina, United States, 27157
Contact: Samuel S. Lentz    336-713-6771      
Principal Investigator: Samuel S. Lentz         
United States, North Dakota
Bismarck Cancer Center Recruiting
Bismarck, North Dakota, United States, 58501
Contact: John T. Reynolds    701-323-5760    tfischer@mohs.org   
Principal Investigator: John T. Reynolds         
Mid Dakota Clinic Terminated
Bismarck, North Dakota, United States, 58501
Saint Alexius Medical Center Terminated
Bismarck, North Dakota, United States, 58501
Sanford Bismarck Medical Center Withdrawn
Bismarck, North Dakota, United States, 58501
Roger Maris Cancer Center Recruiting
Fargo, North Dakota, United States, 58122
Contact: Maria C. Bell    218-333-5000      
Principal Investigator: Maria C. Bell         
Sanford Clinic North-Fargo Recruiting
Fargo, North Dakota, United States, 58122
Contact: Maria C. Bell    218-333-5000      
Principal Investigator: Maria C. Bell         
Sanford Medical Center-Fargo Active, not recruiting
Fargo, North Dakota, United States, 58122
United States, Ohio
Akron General Medical Center Recruiting
Akron, Ohio, United States, 44307
Contact: Esther H. Rehmus    330-344-6348      
Principal Investigator: Esther H. Rehmus         
Summa Akron City Hospital/Cooper Cancer Center Recruiting
Akron, Ohio, United States, 44304
Contact: Vivian E. von Gruenigen    330-375-6101      
Principal Investigator: Vivian E. von Gruenigen         
Strecker Cancer Center-Belpre Recruiting
Belpre, Ohio, United States, 45714
Contact: John P. Kuebler    614-566-3275      
Principal Investigator: John P. Kuebler         
Aultman Health Foundation Active, not recruiting
Canton, Ohio, United States, 44710
Adena Regional Medical Center Recruiting
Chillicothe, Ohio, United States, 45601
Contact: John P. Kuebler    614-566-3275      
Principal Investigator: John P. Kuebler         
Good Samaritan Hospital - Cincinnati Active, not recruiting
Cincinnati, Ohio, United States, 45220
Bethesda North Hospital Terminated
Cincinnati, Ohio, United States, 45242
Cleveland Clinic Cancer Center/Fairview Hospital Recruiting
Cleveland, Ohio, United States, 44111
Contact: Steven E. Waggoner    800-641-2422      
Principal Investigator: Steven E. Waggoner         
Cleveland Clinic Foundation Recruiting
Cleveland, Ohio, United States, 44195
Contact: Steven E. Waggoner    800-641-2422      
Principal Investigator: Steven E. Waggoner         
Case Western Reserve University Recruiting
Cleveland, Ohio, United States, 44106
Contact: Steven E. Waggoner    800-641-2422      
Principal Investigator: Steven E. Waggoner         
MetroHealth Medical Center Active, not recruiting
Cleveland, Ohio, United States, 44109
Ohio State University Medical Center Recruiting
Columbus, Ohio, United States, 43210
Contact: David M. O'Malley    866-627-7616    osu@emergingmed.com   
Principal Investigator: David M. O'Malley         
Columbus Oncology and Hematology Associates Inc Recruiting
Columbus, Ohio, United States, 43214
Contact: John P. Kuebler    614-566-3275      
Principal Investigator: John P. Kuebler         
Columbus CCOP Recruiting
Columbus, Ohio, United States, 43215
Contact: John P. Kuebler    614-566-3275      
Principal Investigator: John P. Kuebler         
Mount Carmel East Hospital Active, not recruiting
Columbus, Ohio, United States, 43213
The Mark H Zangmeister Center Recruiting
Columbus, Ohio, United States, 43219
Contact: John P. Kuebler    614-566-3275      
Principal Investigator: John P. Kuebler         
Doctors Hospital Recruiting
Columbus, Ohio, United States, 43228
Contact: John P. Kuebler    614-566-3275      
Principal Investigator: John P. Kuebler         
Riverside Methodist Hospital Recruiting
Columbus, Ohio, United States, 43214
Contact: Jeffrey G. Bell    614-566-4475      
Principal Investigator: Jeffrey G. Bell         
Mount Carmel Health Center West Recruiting
Columbus, Ohio, United States, 43222
Contact: John P. Kuebler    614-566-3275      
Principal Investigator: John P. Kuebler         
Grant Medical Center Recruiting
Columbus, Ohio, United States, 43215
Contact: John P. Kuebler    614-566-3275      
Principal Investigator: John P. Kuebler         
Grandview Hospital Recruiting
Dayton, Ohio, United States, 45405
Contact: Howard M. Gross    765-983-3000      
Principal Investigator: Howard M. Gross         
Good Samaritan Hospital - Dayton Recruiting
Dayton, Ohio, United States, 45406
Contact: Howard M. Gross    765-983-3000      
Principal Investigator: Howard M. Gross         
Dayton CCOP Recruiting
Dayton, Ohio, United States, 45420
Contact: Howard M. Gross    765-983-3000      
Principal Investigator: Howard M. Gross         
Miami Valley Hospital Recruiting
Dayton, Ohio, United States, 45409
Contact: Howard M. Gross    765-983-3000      
Principal Investigator: Howard M. Gross         
Samaritan North Health Center Terminated
Dayton, Ohio, United States, 45415
Delaware Health Center-Grady Cancer Center Recruiting
Delaware, Ohio, United States, 43015
Contact: John P. Kuebler    614-566-3275      
Principal Investigator: John P. Kuebler         
Grady Memorial Hospital Recruiting
Delaware, Ohio, United States, 43015
Contact: John P. Kuebler    614-566-3275      
Principal Investigator: John P. Kuebler         
Blanchard Valley Hospital Recruiting
Findlay, Ohio, United States, 45840
Contact: Howard M. Gross    765-983-3000      
Principal Investigator: Howard M. Gross         
Atrium Medical Center-Middletown Regional Hospital Recruiting
Franklin, Ohio, United States, 45005-1066
Contact: Howard M. Gross    765-983-3000      
Principal Investigator: Howard M. Gross         
Wayne Hospital Recruiting
Greenville, Ohio, United States, 45331
Contact: Howard M. Gross    765-983-3000      
Principal Investigator: Howard M. Gross         
Fairfield Medical Center Recruiting
Lancaster, Ohio, United States, 43130
Contact: John P. Kuebler    614-566-3275      
Principal Investigator: John P. Kuebler         
Marietta Memorial Hospital Recruiting
Marietta, Ohio, United States, 45750
Contact: John P. Kuebler    614-566-3275      
Principal Investigator: John P. Kuebler         
Hillcrest Hospital Cancer Center Recruiting
Mayfield Heights, Ohio, United States, 44124
Contact: Steven E. Waggoner    800-641-2422      
Principal Investigator: Steven E. Waggoner         
Lake University Ireland Cancer Center Recruiting
Mentor, Ohio, United States, 44060
Contact: Steven E. Waggoner    800-641-2422      
Principal Investigator: Steven E. Waggoner         
Knox Community Hospital Recruiting
Mount Vernon, Ohio, United States, 43050
Contact: John P. Kuebler    614-566-3275      
Principal Investigator: John P. Kuebler         
Licking Memorial Hospital Recruiting
Newark, Ohio, United States, 43055
Contact: John P. Kuebler    614-566-3275      
Principal Investigator: John P. Kuebler         
Southern Ohio Medical Center Recruiting
Portsmouth, Ohio, United States, 45662
Contact: John P. Kuebler    614-566-3275      
Principal Investigator: John P. Kuebler         
Springfield Regional Medical Center Recruiting
Springfield, Ohio, United States, 45505
Contact: John P. Kuebler    614-566-3275      
Principal Investigator: John P. Kuebler         
Upper Valley Medical Center Recruiting
Troy, Ohio, United States, 45373
Contact: Howard M. Gross    765-983-3000      
Principal Investigator: Howard M. Gross         
Saint Ann's Hospital Recruiting
Westerville, Ohio, United States, 43081
Contact: John P. Kuebler    614-566-3275      
Principal Investigator: John P. Kuebler         
Greene Memorial Hospital Terminated
Xenia, Ohio, United States, 45385
Genesis HealthCare System Recruiting
Zanesville, Ohio, United States, 43701
Contact: John P. Kuebler    614-566-3275      
Principal Investigator: John P. Kuebler         
United States, Oklahoma
University of Oklahoma Health Sciences Center Recruiting
Oklahoma City, Oklahoma, United States, 73104
Contact: Robert S. Mannel    405-271-4272    julie-traylor@ouhsc.edu   
Principal Investigator: Robert S. Mannel         
Tulsa Cancer Institute Recruiting
Tulsa, Oklahoma, United States, 74146
Contact: Robert S. Mannel    405-271-4272    julie-traylor@ouhsc.edu   
Principal Investigator: Robert S. Mannel         
Warren Clinic-Tulsa South Recruiting
Tulsa, Oklahoma, United States, 74136
Contact: David G. McIntosh    601-815-6700      
Principal Investigator: David G. McIntosh         
Warren Cancer Research Foundation Recruiting
Tulsa, Oklahoma, United States, 74136
Contact: David G. McIntosh    601-815-6700      
Principal Investigator: David G. McIntosh         
Natalie Warren Bryant Cancer Center at Saint Francis Recruiting
Tulsa, Oklahoma, United States, 74136
Contact: David G. McIntosh    601-815-6700      
Principal Investigator: David G. McIntosh         
United States, Pennsylvania
Saint Luke's University Hospital-Bethlehem Campus Recruiting
Bethlehem, Pennsylvania, United States, 18015
Contact: Nicholas P. Taylor    610-954-3582    infolink@slhn.org   
Principal Investigator: Nicholas P. Taylor         
Adams Cancer Center Recruiting
Gettysburg, Pennsylvania, United States, 17325
Contact: Timothy B. McGuinness    877-441-7957      
Principal Investigator: Timothy B. McGuinness         
Cherry Tree Cancer Center Recruiting
Hanover, Pennsylvania, United States, 17331
Contact: Timothy B. McGuinness    877-441-7957      
Principal Investigator: Timothy B. McGuinness         
Fox Chase Cancer Center Recruiting
Philadelphia, Pennsylvania, United States, 19111-2497
Contact: Stephaine A. King    215-728-4790      
Principal Investigator: Stephaine A. King         
Temple University Hospital Recruiting
Philadelphia, Pennsylvania, United States, 19140
Contact: Enrique Hernandez    215-728-2983      
Principal Investigator: Enrique Hernandez         
Thomas Jefferson University Hospital Recruiting
Philadelphia, Pennsylvania, United States, 19107
Contact: Allison M. Zibelli    215-955-6084      
Principal Investigator: Allison M. Zibelli         
University of Pittsburgh Recruiting
Pittsburgh, Pennsylvania, United States, 15232
Contact: Robert P. Edwards    412-647-2811      
Principal Investigator: Robert P. Edwards         
Guthrie Medical Group PC-Robert Packer Hospital Terminated
Sayre, Pennsylvania, United States, 18840
Chester County Hospital Terminated
West Chester, Pennsylvania, United States, 19380
Reading Hospital Recruiting
West Reading, Pennsylvania, United States, 19611
Contact: Bernice L. Robinson-Bennett    610-988-9323      
Principal Investigator: Bernice L. Robinson-Bennett         
WellSpan Health-York Hospital Recruiting
York, Pennsylvania, United States, 17405
Contact: Timothy B. McGuinness    877-441-7957      
Principal Investigator: Timothy B. McGuinness         
United States, Rhode Island
Women and Infants Hospital Recruiting
Providence, Rhode Island, United States, 02905
Contact: Paul A. DiSilvestro    401-274-1122      
Principal Investigator: Paul A. DiSilvestro         
United States, South Dakota
Avera Cancer Institute Recruiting
Sioux Falls, South Dakota, United States, 57105
Contact: Luis A. Rojas-Espaillat    800-657-4377    Jan.Healy@avera.org   
Principal Investigator: Luis A. Rojas-Espaillat         
Sanford Cancer Center-Oncology Clinic Recruiting
Sioux Falls, South Dakota, United States, 57104
Contact: Maria C. Bell    218-333-5000      
Principal Investigator: Maria C. Bell         
Sanford USD Medical Center - Sioux Falls Recruiting
Sioux Falls, South Dakota, United States, 57117-5134
Contact: Maria C. Bell    218-333-5000      
Principal Investigator: Maria C. Bell         
United States, Tennessee
University of Tennessee - Knoxville Terminated
Knoxville, Tennessee, United States, 37920
United States, Texas
M D Anderson Cancer Center Recruiting
Houston, Texas, United States, 77030
Contact: Jubilee Brown    713-792-3245    jbbrown@mdanderson.org   
Principal Investigator: Jubilee Brown         
M D Anderson Cancer Center Active, not recruiting
Houston, Texas, United States, 77030
Scott and White Memorial Hospital Active, not recruiting
Temple, Texas, United States, 76508
United States, Vermont
Fletcher Allen Health Care-Medical Center Recruiting
Burlington, Vermont, United States, 05401
Contact: Cheung Wong    802-656-8990      
Principal Investigator: Cheung Wong         
United States, Virginia
Carilion Clinic Gynecological Oncology Recruiting
Roanoke, Virginia, United States, 24016
Contact: Janet L. Osborne    540-985-8510      
Principal Investigator: Janet L. Osborne         
United States, West Virginia
Monongalia Hospital Active, not recruiting
Morgantown, West Virginia, United States, 26505
United States, Wisconsin
Marshfield Clinic Cancer Center at Sacred Heart Recruiting
Eau Claire, Wisconsin, United States, 54701
Contact: Anthony C. Evans    715-389-4457      
Principal Investigator: Anthony C. Evans         
Green Bay Oncology at Saint Vincent Hospital Recruiting
Green Bay, Wisconsin, United States, 54301-3526
Contact: Jonathan E. Tammela    920-433-8889      
Principal Investigator: Jonathan E. Tammela         
Saint Mary's Hospital Recruiting
Green Bay, Wisconsin, United States, 54303
Contact: Jonathan E. Tammela    920-433-8889      
Principal Investigator: Jonathan E. Tammela         
Saint Vincent Hospital Recruiting
Green Bay, Wisconsin, United States, 54301
Contact: Jonathan E. Tammela    920-433-8889      
Principal Investigator: Jonathan E. Tammela         
Green Bay Oncology Limited at Saint Mary's Hospital Recruiting
Green Bay, Wisconsin, United States, 54303
Contact: Jonathan E. Tammela    920-433-8889      
Principal Investigator: Jonathan E. Tammela         
Gundersen Lutheran Terminated
La Crosse, Wisconsin, United States, 54601
University of Wisconsin Hospital and Clinics Recruiting
Madison, Wisconsin, United States, 53792
Contact: David M. Kushner    877-405-6866      
Principal Investigator: David M. Kushner         
Holy Family Memorial Hospital Recruiting
Manitowoc, Wisconsin, United States, 54221
Contact: Jonathan E. Tammela    920-433-8889      
Principal Investigator: Jonathan E. Tammela         
Bay Area Medical Center Recruiting
Marinette, Wisconsin, United States, 54143
Contact: Jonathan E. Tammela    920-433-8889      
Principal Investigator: Jonathan E. Tammela         
Marshfield Clinic Recruiting
Marshfield, Wisconsin, United States, 54449
Contact: Anthony C. Evans    715-389-4457      
Principal Investigator: Anthony C. Evans         
Froedtert and the Medical College of Wisconsin Recruiting
Milwaukee, Wisconsin, United States, 53226
Contact: William H. Bradley    414-805-4380      
Principal Investigator: William H. Bradley         
Aurora Saint Luke's Medical Center Recruiting
Milwaukee, Wisconsin, United States, 53215
Contact: Scott A. Kamelle    414-649-7200      
Principal Investigator: Scott A. Kamelle         
Marshfield Clinic-Minocqua Center Recruiting
Minocqua, Wisconsin, United States, 54548
Contact: Anthony C. Evans    715-389-4457      
Principal Investigator: Anthony C. Evans         
D N Greenwald Center Recruiting
Mukwonago, Wisconsin, United States, 53149
Contact: Janet G. Drake    262-928-7632      
Principal Investigator: Janet G. Drake         
Oconomowoc Memorial Hospital-ProHealth Care Inc Recruiting
Oconomowoc, Wisconsin, United States, 53066-3896
Contact: Janet G. Drake    262-928-7632      
Principal Investigator: Janet G. Drake         
Green Bay Oncology - Oconto Falls Recruiting
Oconto Falls, Wisconsin, United States, 54154
Contact: Jonathan E. Tammela    920-433-8889      
Principal Investigator: Jonathan E. Tammela         
Vince Lombardi Cancer Clinic - Oshkosh Recruiting
Oshkosh, Wisconsin, United States, 54904
Contact: Zahid N. Dar    800-252-2990      
Principal Investigator: Zahid N. Dar         
Marshfield Clinic at James Beck Cancer Center Recruiting
Rhinelander, Wisconsin, United States, 54501
Contact: Anthony C. Evans    715-389-4457      
Principal Investigator: Anthony C. Evans         
Marshfield Clinic-Rice Lake Center Recruiting
Rice Lake, Wisconsin, United States, 54868
Contact: Anthony C. Evans    715-389-4457      
Principal Investigator: Anthony C. Evans         
Vince Lombardi Cancer Clinic-Sheboygan Recruiting
Sheboygan, Wisconsin, United States, 53081
Contact: Santhosh Kumar    414-649-7200      
Principal Investigator: Santhosh Kumar         
Marshfield Clinic Cancer Care at Saint Michael's Hospital Recruiting
Stevens Point, Wisconsin, United States, 54481
Contact: Anthony C. Evans    715-389-4457      
Principal Investigator: Anthony C. Evans         
Green Bay Oncology - Sturgeon Bay Recruiting
Sturgeon Bay, Wisconsin, United States, 54235
Contact: Jonathan E. Tammela    920-433-8889      
Principal Investigator: Jonathan E. Tammela         
Aurora Medical Center in Summit Recruiting
Summit, Wisconsin, United States, 53066
Contact: Ali Mahdavi    414-649-5717    ucstudy@uci.edu   
Principal Investigator: Ali Mahdavi         
Waukesha Memorial Hospital - ProHealth Care Recruiting
Waukesha, Wisconsin, United States, 53188
Contact: Janet G. Drake    262-928-7632      
Principal Investigator: Janet G. Drake         
Marshfield Clinic-Wausau Center Recruiting
Wausau, Wisconsin, United States, 54401
Contact: Anthony C. Evans    715-389-4457      
Principal Investigator: Anthony C. Evans         
Aurora Women's Pavilion of Aurora West Allis Medical Center Recruiting
West Allis, Wisconsin, United States, 53227
Contact: Peter R. Johnson    800-252-2990      
Principal Investigator: Peter R. Johnson         
Marshfield Clinic - Weston Center Recruiting
Weston, Wisconsin, United States, 54476
Contact: Anthony C. Evans    715-389-4457      
Principal Investigator: Anthony C. Evans         
Marshfield Clinic - Wisconsin Rapids Center Recruiting
Wisconsin Rapids, Wisconsin, United States, 54494
Contact: Anthony C. Evans    715-389-4457      
Principal Investigator: Anthony C. Evans         
United States, Wyoming
Rocky Mountain Oncology Recruiting
Casper, Wyoming, United States, 82609
Contact: Benjamin T. Marchello    800-648-6274      
Principal Investigator: Benjamin T. Marchello         
Welch Cancer Center Recruiting
Sheridan, Wyoming, United States, 82801
Contact: Benjamin T. Marchello    800-648-6274      
Principal Investigator: Benjamin T. Marchello         
Sponsors and Collaborators
Gynecologic Oncology Group
Investigators
Principal Investigator: Vivian von Gruenigen Gynecologic Oncology Group
  More Information

No publications provided

Responsible Party: Gynecologic Oncology Group
ClinicalTrials.gov Identifier: NCT01366183     History of Changes
Other Study ID Numbers: GOG-0273, NCI-2011-02900, GOG-0273, GOG-0273, GOG-0273, U10CA101165
Study First Received: June 2, 2011
Last Updated: March 25, 2014
Health Authority: United States: Institutional Review Board

Additional relevant MeSH terms:
Peritoneal Neoplasms
Fallopian Tube Neoplasms
Neoplasms, Glandular and Epithelial
Ovarian Neoplasms
Abdominal Neoplasms
Neoplasms by Site
Neoplasms
Digestive System Neoplasms
Digestive System Diseases
Peritoneal Diseases
Genital Neoplasms, Female
Urogenital Neoplasms
Fallopian Tube Diseases
Adnexal Diseases
Genital Diseases, Female
Neoplasms by Histologic Type
Endocrine Gland Neoplasms
Ovarian Diseases
Endocrine System Diseases
Gonadal Disorders
Carboplatin
Paclitaxel
Lenograstim
Antineoplastic Agents
Therapeutic Uses
Pharmacologic Actions
Tubulin Modulators
Antimitotic Agents
Mitosis Modulators
Molecular Mechanisms of Pharmacological Action

ClinicalTrials.gov processed this record on April 23, 2014