Cytokine Levels in Conversion Disorder

This study has been completed.

Sponsor:

Information provided by:

Trakya University

ClinicalTrials.gov Identifier:

NCT00971360

First received: September 2, 2009

Last updated: October 19, 2010

Last verified: September 2009

History of Changes

Purpose

The aim of this study is whether the proinflammatory cytokine levels in patients with conversion disorder is increased or not changed in the acute phase and subacute - chronic periode, compared with controls.

Condition	Intervention
Conversion Disorder	Other: conversion disorder

Study Type:	Observational
Study Design:	Observational Model: Cohort Time Perspective: Prospective
Official Title:	Proinflammatory Cytokine Levels in Patients With Conversion Disorder

Further study details as provided by Trakya University:

Estimated Enrollment:	30
Study Start Date:	September 2009
Study Completion Date:	September 2010
Primary Completion Date:	September 2010 (Final data collection date for primary outcome measure)

Groups/Cohorts	Assigned Interventions
Conversion disorder	Other: conversion disorder Proinflammatory cytokine levels in conversion disorder
Healthy control	Other: conversion disorder Proinflammatory cytokine levels in conversion disorder

Eligibility

Ages Eligible for Study:	18 Years to 65 Years
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No
Sampling Method:	Non-Probability Sample

Study Population

primary care clinic

Criteria

Inclusion Criteria:

Clinical diagnosis of Alzheimer's Disease

Exclusion Criteria:

Autoimmune disease
Neurological disease
Any organic disorder that could possibly affect proinflammatory cytokines
Pregnancy
Any drug usage within 2 weeks
Any active or passive immunization within 6 months
Any other DSM-IV axis I psychiatric disorder
Mental retardation
Developmental disorder of childhood

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00971360

Locations

Turkey
Trakya University Faculty of Medicine; Department of Psychiatry
Edirne, Turkey, 22030

Sponsors and Collaborators

Trakya University

More Information

Publications:

Rief W, Pilger F, Ihle D, Bosmans E, Egyed B, Maes M. Immunological differences between patients with major depression and somatization syndrome. Psychiatry Res. 2001 Dec 31;105(3):165-74.

Ziemssen T, Kern S. Psychoneuroimmunology--cross-talk between the immune and nervous systems. J Neurol. 2007 May;254 Suppl 2:II8-11. Review. Erratum in: J Neurol. 2008 Feb;255(2):309-10.

Dantzer R. Somatization: a psychoneuroimmune perspective. Psychoneuroendocrinology. 2005 Nov;30(10):947-52. Review.

Responsible Party:	Trakya University Scientific Research Unit (TUBAB)
ClinicalTrials.gov Identifier:	NCT00971360 History of Changes
Other Study ID Numbers:	TUTFEK 2009/173
Study First Received:	September 2, 2009
Last Updated:	October 19, 2010
Health Authority:	United States: Institutional Review Board Turkey: Ethics Committee

Keywords provided by Trakya University:

conversion
cytokine
inflammation

Additional relevant MeSH terms:

Conversion Disorder
Hysteria
Dissociative Disorders
Somatoform Disorders

Mental Disorders
Histrionic Personality Disorder
Personality Disorders

ClinicalTrials.gov processed this record on May 21, 2013

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