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| Sponsor: | University of Alabama at Birmingham |
|---|---|
| Information provided by: | University of Alabama at Birmingham |
| ClinicalTrials.gov Identifier: | NCT00699595 |
Purpose
To investigate if labor pain is affected by mother's hormone levels.
The hormonal effects of pregnancy are well documented. Although differences in pain sensitivity between women and men are partly attributable to social conditioning and to psychosocial factors, many laboratory studies of humans have described sex differences in sensitivity to noxious stimuli, suggesting that biological mechanisms underlie such differences. Some animal studies have suggested that sensitivity to pain decreases during pregnancy because of the progressive activation of endogenous pain inhibitory systems. This effect may be mediated by pregnancy-associated hormones, in particular progesterone.
| Condition |
|---|
|
Pregnancy Progesterone Levels Pregnancy Associated Analgesia |
| Study Type: | Observational |
| Study Design: | Cohort, Prospective |
| Official Title: | Hormonal Effects on Pain Perception |
Plasma for progesterone levels
| Estimated Enrollment: | 60 |
| Study Start Date: | September 2008 |
| Estimated Study Completion Date: | September 2010 |
| Estimated Primary Completion Date: | September 2010 (Final data collection date for primary outcome measure) |
| Groups/Cohorts |
|---|
|
Term pregnant women
Healthy women scheduled for elective Cesarean section.
|
Eligibility| Ages Eligible for Study: | 19 Years to 45 Years |
| Genders Eligible for Study: | Female |
| Accepts Healthy Volunteers: | Yes |
| Sampling Method: | Non-Probability Sample |
Healthy term pregnant women
Inclusion Criteria:
Exclusion Criteria:
Contacts and Locations| Contact: Michael Froelich, MD, MS | 205-975-0145 | froelich@uab.edu |
| Contact: Jeff Worrell, RN, BSN | 205-975-2098 | jworrell@uab.edu |
| United States, Alabama | |
| University of Alabama at Birmingham | Recruiting |
| Birmingham, Alabama, United States, 35294 | |
| Contact: Debbie Owen 205-975-2088 debbie0@uab.edu | |
| Contact: Jeff Worrell, RN, BSN 205-975-2098 jworrell@uab.edu | |
| Principal Investigator: Michael Froelich, MD, MS | |
| Sub-Investigator: Brian T. Torgerson, MD | |
| Principal Investigator: | Michael Froelich, MD, MS | University of Alabama at Birmingham |
More Information
| Responsible Party: | University at Alabama at Birmingham ( Michael Froelich, MD ) |
| Study ID Numbers: | F070721003 |
| Study First Received: | June 13, 2008 |
| Last Updated: | November 2, 2009 |
| ClinicalTrials.gov Identifier: | NCT00699595 History of Changes |
| Health Authority: | United States: Institutional Review Board |