Improving Walking in Older Adults With Knee Osteoarthritis - Full Text View

Sponsor:	University of Iowa
Collaborator:	National Institute on Aging (NIA)
Information provided by:	University of Iowa
ClinicalTrials.gov Identifier:	NCT00583245

Purpose

Knee osteoarthritis (OA) accounts for a significant proportion of mobility limitations and is one of the most disabling problems facing the growing population of older adults. The long-term objective of this research is to reduce disablement of older adults with symptomatic knee OA. The principle of specificity of training indicates that exercises that closely approximate the goal functional activity are most effective in improving physical performance during that activity. Based on this principle, the specific aim of this pilot study is to design a patient-specific gait training intervention using analysis of compensatory joint moments and energy expenditure. Successful completion will inform rehabilitation for maintaining or improving mobility as well as explore the mechanism of effect.

Condition	Intervention
Knee Osteoarthritis	Other: Gait Training

Study Type:	Interventional
Study Design:	Treatment, Non-Randomized, Open Label, Uncontrolled, Single Group Assignment, Safety/Efficacy Study
Official Title:	Optimizing Mobility in Older Adults With Knee Osteoarthritis

Resource links provided by NLM:

MedlinePlus related topics: Osteoarthritis Rehabilitation

U.S. FDA Resources

Further study details as provided by University of Iowa:

Primary Outcome Measures:

Changes in functional limitation assessed by the A) Summary Performance Score which includes balance tests, timed 4-meter walk, and timed chair stand test B) Timed stair climb C) Late Life Function and Disability Instrument (LLFDI) Questionnaire [ Time Frame: 12 weeks ] [ Designated as safety issue: No ]
Changes in the disability measure, a timed 400 meter walk [ Time Frame: 12 Weeks ] [ Designated as safety issue: No ]
Changes in impairments assessed using the Knee and Osteoarthritis Outcome Score (KOOS) questionnaire [ Time Frame: 12 Weeks ] [ Designated as safety issue: No ]

Estimated Enrollment:	30
Study Start Date:	December 2007
Estimated Study Completion Date:	December 2009
Estimated Primary Completion Date:	September 2008 (Final data collection date for primary outcome measure)

Arms	Assigned Interventions
1: Experimental Gait training	Other: Gait Training Gait training with physical therapist 2/week for 3 months

Eligibility

Ages Eligible for Study:	60 Years and older
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No

Criteria

Inclusion Criteria:

Symptomatic knee osteoarthritis (knee osteoarthritis diagnosed by x-ray and frequent knee symptoms)
Age 60 or older

Exclusion Criteria:

acute or terminal illness
unstable cardiovascular condition or other medical conditions that may impair ability to participate such as pulmonary disease requiring the use of supplemental oxygen, neurological disease that affects gait, or lower limb musculoskeletal surgery in the past 6 months.
Bilateral knee replacement

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00583245

Locations

United States, Iowa
University of Iowa Hospitals and Clinics
Iowa City, Iowa, United States, 52242

Sponsors and Collaborators

University of Iowa

National Institute on Aging (NIA)

Investigators

Principal Investigator:

Neil Segal, MD

University of Iowa

More Information

No publications provided

Responsible Party:	The University of Iowa ( Neil Segal, MD )
Study ID Numbers:	NCT00331110, 1K23AG030945-01
Study First Received:	December 20, 2007
Last Updated:	February 13, 2009
ClinicalTrials.gov Identifier:	NCT00583245 History of Changes
Health Authority:	United States: Institutional Review Board

Keywords provided by University of Iowa:

Osteoarthritis
Gait training
Knee pain
Rehabilitation
Physical Therapy

Additional relevant MeSH terms:

Osteoarthritis, Knee
Musculoskeletal Diseases
Osteoarthritis

Joint Diseases
Arthritis
Rheumatic Diseases

ClinicalTrials.gov processed this record on November 22, 2009