Apixaban for the Prevention of Stroke in Subjects With Atrial Fibrillation (ARISTOTLE)

This study has been completed.

Sponsor:

Information provided by (Responsible Party):

Bristol-Myers Squibb

ClinicalTrials.gov Identifier:

NCT00412984

First received: December 18, 2006

Last updated: April 29, 2013

Last verified: April 2013

History of Changes

Purpose

The trial seeks to determine if apixaban, an investigational anticoagulant (blood-thinner) is as effective as standard therapy (warfarin) in preventing stroke and systemic embolism in subjects with atrial fibrillation and risk factors for stroke.

Condition	Intervention	Phase
Atrial Fibrillation Atrial Flutter	Drug: warfarin Drug: apixaban	Phase 3

Study Type:	Interventional
Study Design:	Allocation: Randomized Endpoint Classification: Efficacy Study Intervention Model: Parallel Assignment Masking: Double Blind (Subject, Investigator) Primary Purpose: Prevention
Official Title:	A Phase 3, Active (Warfarin) Controlled, Randomized, Double-Blind, Parallel Arm Study to Evaluate Efficacy and Safety of Apixaban in Preventing Stroke and Systemic Embolism in Subjects With Nonvalvular Atrial Fibrillation

Resource links provided by NLM:

Genetics Home Reference related topics: familial atrial fibrillation

MedlinePlus related topics: Atrial Fibrillation Blood Thinners

Drug Information available for: Warfarin Warfarin sodium Apixaban

U.S. FDA Resources

Further study details as provided by Bristol-Myers Squibb:

Primary Outcome Measures:

Number of Participants With First Event of Ischemic/Unspecified Stroke, Hemorrhagic Stroke, or Systemic Embolism (SE) During the Intended Treatment Period [ Time Frame: Time to first event in "Intended Treatment Period": started on day of randomization, ended at efficacy cut-off date (date target number of primary efficacy events [448] was expected to have occurred; set to 30-Jan-2011, prior to unblinding). ] [ Designated as safety issue: No ]
All suspected efficacy events were adjudicated by the Central Events Committee (CEC). Diagnosis of stroke=the nontraumatic focal neurological deficit lasting at least 24 hours, and includes ischemic stroke, hemorrhagic stroke, ischemic stroke with hemorrhagic conversion, stroke of uncertain type, and retinal ischemic event (embolism, infarction). Diagnosis of SE=clinical history consistent with an acute loss of blood flow to a peripheral artery (or arteries), supported by evidence of embolism from surgical specimens, autopsy, angiography, vascular imaging, or other objective testing.
Rate of Adjudicated Stroke or Systemic Embolism (SE) During the Intended Treatment Period [ Time Frame: "Intended Treatment Period" started on the day of randomization and ended at the efficacy cut-off date (date on which it was expected that the target number of primary efficacy events [448] would have occurred; set to 30-Jan-2011, prior to unblinding). ] [ Designated as safety issue: No ]
Rate=Number of adjudicated stroke or SE events per 100 patient years. Diagnosis of stroke=the nontraumatic focal neurological deficit lasting at least 24 hours, and includes ischemic stroke, hemorrhagic stroke, ischemic stroke with hemorrhagic conversion, stroke of uncertain type, and retinal ischemic event (embolism, infarction). Diagnosis of SE=clinical history consistent with an acute loss of blood flow to a peripheral artery (or arteries), supported by evidence of embolism from surgical specimens, autopsy, angiography, vascular imaging, or other objective testing.
Number of Participants With Event of Major (International Society on Thrombosis and Hemostasis [ISTH]) Bleeding During Treatment Period [ Time Frame: "Treatment Period" started with first dose of blinded study drug and ended 2 days after the last dose of blinded study drug. Mean duration of exposure to double-blind study drug was 1.7 years in each treatment group. ] [ Designated as safety issue: Yes ]
ISTH Bleeding Criteria: Major bleeding=a bleeding event that was: clinically overt bleeding accompanied by a decrease in hemoglobin (Hgb) of 2 g/dL or more and/or a transfusion of 2 or more units of packed red blood cells; bleeding that occurred in at least one of the following critical sites: intracranial, intraspinal, intraocular (within the corpus of the eye; a conjunctival bleed is not an intraocular bleed), pericardial, intra-articular, intramuscular with compartment syndrome, and retroperitoneal; bleeding that was fatal.
Rate of Adjudicated Major (ISTH) Bleed Events During Treatment Period [ Time Frame: "Treatment Period" started with first dose of blinded study drug and ended 2 days after the last dose of blinded study drug. Mean duration of exposure to double-blind study drug was 1.7 years in each treatment group. ] [ Designated as safety issue: Yes ]
Rate=number of adjudicated major (ISTH) bleed events per 100 patient years. ISTH Bleeding Criteria: Major bleeding=a bleeding event that was: clinically overt bleeding accompanied by a decrease in hemoglobin (Hgb) of 2 g/dL or more and/or a transfusion of 2 or more units of packed red blood cells; bleeding that occurred in at least 1 of the following sites: intracranial, intraspinal, intraocular (within the corpus of the eye; a conjunctival bleed is not an intraocular bleed), pericardial, intra-articular, intramuscular with compartment syndrome, and retroperitoneal; bleeding that was fatal.

Secondary Outcome Measures:

Number of Participants With Events of All-Cause Death During the Intended Treatment Period [ Time Frame: "Intended Treatment Period" started on the day of randomization and ended at the efficacy cut-off date (date on which it was expected that the target number of primary efficacy events [448] would have occurred; set to 30-Jan-2011, prior to unblinding). ] [ Designated as safety issue: No ]
Death was defined as all-cause mortality. All unobserved deaths were assumed to be cardiovascular in nature unless a non-cardiovascular cause could be clearly provided. Cardiovascular=deaths due to ischemic and hemorrhagic stroke, SE, myocardial infarction (MI), sudden death, heart failure, other cardiovascular, and unobserved deaths. Non-cardiovascular=all deaths due to a clearly documented non-cardiovascular cause (further classified into the categories: bleeding, study drug toxicity other than bleeding, malignancy, infection, trauma, and pulmonary causes of death).
Rate of Adjudicated All-Cause Death During the Intended Treatment Period [ Time Frame: "Intended Treatment Period" started on the day of randomization and ended at the efficacy cut-off date (date on which it was expected that the target number of primary efficacy events [448] would have occurred; set to 30-Jan-2011, prior to unblinding). ] [ Designated as safety issue: No ]
All unobserved deaths were assumed to be cardiovascular in nature unless a non-cardiovascular cause could be clearly provided. Cardiovascular=deaths due to ischemic and hemorrhagic stroke, SE, MI, sudden death, heart failure, other cardiovascular, and unobserved deaths. Non-cardiovascular=all deaths due to a clearly documented non-cardiovascular cause (further classified into the categories: bleeding, study drug toxicity other than bleeding, malignancy, infection, trauma, and pulmonary causes of death).
Rate of Ischemic or Unspecified Stroke, Hemorrhagic Stroke, Systemic Embolism (SE), and Myocardial Infarction (MI) (as Individual Endpoints) During the Intended Treatment Period [ Time Frame: "Intended Treatment Period" started on the day of randomization and ended at the efficacy cut-off date (date on which it was expected that the target number of primary efficacy events [448] would have occurred; set to 30-Jan-2011, prior to unblinding). ] [ Designated as safety issue: No ]
Diagnosis for an acute or evolving MI=elevation of creatine kinase-MB isoenzyme (CK-MB) or Troponin T or I ≥ 2 × the upper limit of normal (ULN), or if no CK-MB or troponin values are available, a total CK ≥ 2×ULN, or new, significant (≥0.04 s) Q waves in ≥2 contiguous leads. For descriptions of Stroke and SE, see Outcome Measure 1.
Rate of Ischemic or Unspecified Stroke, Hemorrhagic Stroke, Systemic Embolism (SE), Myocardial Infarction (MI) and All-Cause Death (ACD) (as Composite Endpoints) During the Intended Treatment Period [ Time Frame: "Intended Treatment Period" started on the day of randomization and ended at the efficacy cut-off date (date on which it was expected that the target number of primary efficacy events [448] would have occurred; set to 30-Jan-2011, prior to unblinding). ] [ Designated as safety issue: No ]
Diagnosis for an acute or evolving MI=elevation of CK-MB or Troponin T or I ≥ 2 × the ULN, or if no CK-MB or troponin values are available, a total CK ≥ 2×ULN, or new, significant (≥0.04 s) Q waves in ≥2 contiguous leads. For descriptions of Stroke and SE, see Outcome Measure 1. For description of ACD, see Outcome Measure 5.
Number of Warfarin/Vitamin K Antagonist (VKA) Naive Participants With Composite Stroke / Systemic Embolism (SE) / Major Bleeding During the Intended Treatment Period [ Time Frame: "Intended Treatment Period" started on the day of randomization and ended at the efficacy cut-off date (date on which it was expected that the target number of primary efficacy events [448] would have occurred; set to 30-Jan-2011, prior to unblinding). ] [ Designated as safety issue: No ]
For descriptions of Stroke and SE, see Outcome Measure 1. For description of Major bleeding, see Outcome Measure 3.
Rate of Composite Stroke / Systemic Embolism / Major Bleeding in Warfarin/Vitamin K Antagonist (VKA) Naive Participants During the Intended Treatment Period [ Time Frame: "Intended Treatment Period" started on the day of randomization and ended at the efficacy cut-off date (date on which it was expected that the target number of primary efficacy events [448] would have occurred; set to 30-Jan-2011, prior to unblinding). ] [ Designated as safety issue: No ]
Number of Participants With Events of Major or Clinically Relevant Non-Major (CRNM) Bleed During Treatment Period [ Time Frame: "Treatment Period" started with first dose of blinded study drug and ended 2 days after the last dose of blinded study drug. Mean duration of exposure to double-blind study drug was 1.7 years in each treatment group. ] [ Designated as safety issue: Yes ]
Major bleeding=bleeding that is clinically overt and that either 1) resulted in a decrease in hemoglobin of 2 g/dL or more over a 24-hour period, or 2)led to a transfusion of 2 or more units of packed red blood cells, or 3) occurred in a critical site, or 4) led to death. CRNM bleeding=bleeding that is clinically overt, that satisfies none of the additional criteria required for the event to be adjudicated as a major bleeding event, that led to either 1) hospital admission for bleeding or 2) physician guided medical or surgical treatment for bleeding or 3) a change in antithrombotic therapy.
Rate of Events of Major or Clinically Relevant Non-Major (CRNM) Bleed During Treatment Period [ Time Frame: "Treatment Period" started with first dose of blinded study drug and ended 2 days after the last dose of blinded study drug. Mean duration of exposure to double-blind study drug was 1.7 years in each treatment group. ] [ Designated as safety issue: Yes ]
Rate=number of major or CRNM bleed events per 100 patient years. Major=clinically overt and either 1) resulted in a decrease in hemoglobin of 2 g/dL or more over a 24-hour period, or 2) led to a transfusion of 2 or more units of packed red blood cells, or 3) occurred in a critical site, or 4) led to death. CRNM bleeding=clinically overt, but satisfied no additional criteria required to be adjudicated as a major bleeding event, and led to either 1) hospital admission for bleeding or 2) physician guided medical or surgical treatment for bleeding or 3) a change in antithrombotic therapy.
Number of Participants With All Bleeding Events During Treatment Period [ Time Frame: "Treatment Period" started with first dose of blinded study drug and ended 2 days after the last dose of blinded study drug. Mean duration of exposure to double-blind study drug was 1.7 years in each treatment group. ] [ Designated as safety issue: Yes ]
All bleeding events include major bleeding, CRNM bleeding (see Outcome Measure 12 Description for definitions), plus events of minor bleeding and fatal bleeding. Minor bleeding: All acute clinically overt bleeding events not meeting the criteria for either major bleeding or clinically relevant non-major bleeding will be classified as minor bleeding. Fatal bleeding is defined as a bleeding event that the Clinical Events Committee determines is the primary cause of death or contributes directly to death.
Rate of All Bleeding Events During Treatment Period [ Time Frame: "Treatment Period" started with first dose of blinded study drug and ended 2 days after the last dose of blinded study drug. Mean duration of exposure to double-blind study drug was 1.7 years in each treatment group. ] [ Designated as safety issue: Yes ]
Rate=number of all bleeding events per 100 patient years. "All bleeding events" include major bleeding, CRNM bleeding (see Outcome Measure 12 Description for definitions), plus events of minor bleeding and fatal bleeding. Minor bleeding: All acute clinically overt bleeding events not meeting the criteria for either major bleeding or clinically relevant non-major bleeding will be classified as minor bleeding. Fatal bleeding is defined as a bleeding event that the Clinical Events Committee determines is the primary cause of death or contributes directly to death.

Other Outcome Measures:

Number of Participants With Adverse Events (AEs), Bleeding AEs, Serious Adverse Events (SAEs), Discontinuations Due to AEs, or Deaths During the Treatment Period [ Time Frame: "Treatment Period" started with first dose of blinded study drug and ended 2 days after the last dose of blinded study drug. Mean duration of exposure to double-blind study drug was 1.7 years in each treatment group. ] [ Designated as safety issue: Yes ]
AE: all SAEs or AEs with onset from first dose through 2 days (AEs) or 30 days (SAEs) after the last dose of blinded study drug (BSD). SAE: all SAEs with onset from first dose through 30 days after the last dose of BSD. Bleeding AE: all serious or non-serious bleeding-related AEs with onset from first dose through 2 days after the last dose of BSD. Discontinuations due to AE: all SAEs or AEs with onset from first dose of BSD and with action taken=drug discontinued. Deaths: all deaths occurring from first dose through 30 days after the last dose of BSD.
Rate of Adjudicated Bleeding Endpoints Per Global Use of Strategies to Open Occluded Coronary Arteries (GUSTO) During the Treatment Period [ Time Frame: "Treatment Period" started with first dose of blinded study drug and ended 2 days after the last dose of blinded study drug. Mean duration of exposure to double-blind study drug was 1.7 years in each treatment group. ] [ Designated as safety issue: Yes ]
Rate=number of adjudicated GUSTO bleeding events per 100 patient years. GUSTO Bleeding Criteria: GUSTO severe (or life-threatening) bleeding: either intracranial hemorrhage or bleeding that causes hemodynamic compromise and requires intervention. GUSTO moderate bleeding: bleeding that requires blood transfusion but does not result in hemodynamic compromise.
Rate of Adjudicated Bleeding Endpoints Per Thrombolysis in Myocardial Infarction (TIMI) During the Treatment Period [ Time Frame: "Treatment Period" started with first dose of blinded study drug and ended 2 days after the last dose of blinded study drug. Mean duration of exposure to double-blind study drug was 1.7 years in each treatment group. ] [ Designated as safety issue: Yes ]
Rate=number of adjudicated TIMI bleeding events per 100 patient years. TIMI Bleeding Criteria: Major bleeding=Intracranial bleeding and/or clinically overt bleeding associated with ≥5 gm/dL fall in Hgb or 15% fall in hematocrit (Hct) from baseline, accounting for transfusions. Minor bleeding=Clinically overt bleeding associated with ≥3 gm/dL fall in Hgb or a ≥10% fall in Hct from baseline, accounting for transfusions.
Number of Participants With Net-Clinical Benefit During Treatment Period [ Time Frame: "Treatment Period" started with first dose of blinded study drug and ended 2 days after the last dose of blinded study drug. Mean duration of exposure to double-blind study drug was 1.7 years in each treatment group. ] [ Designated as safety issue: No ]
Net-Clinical Benefit = Composite of stroke, systemic embolism and ISTH major bleeding.
Rate of Net-Clinical Benefit During Treatment Period [ Time Frame: "Treatment Period" started with first dose of blinded study drug and ended 2 days after the last dose of blinded study drug. Mean duration of exposure to double-blind study drug was 1.7 years in each treatment group. ] [ Designated as safety issue: Yes ]
Rate=number of events of net-clinical benefit per 100 patient years. Net-Clinical Benefit = Composite of stroke, systemic embolism and ISTH major bleeding

Enrollment:	18201
Study Start Date:	December 2006
Study Completion Date:	June 2011
Primary Completion Date:	June 2011 (Final data collection date for primary outcome measure)

Arms	Assigned Interventions
Active Comparator: 1	Drug: warfarin Oral tablets, 2.0 mg, adjusted to an INR of 2.5 (range 2.0 to 3.0) Other Names: Coumadin BMS-565793
Experimental: 2	Drug: apixaban Oral tablets, 5.0 mg or 2.5 mg, twice daily Other Name: BMS-562247

Eligibility

Ages Eligible for Study:	18 Years and older
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No

Criteria

Inclusion Criteria:

Males and females ≥ 18 yrs with atrial fibrillation (AF) and one or more of the following risk factors for stroke:
Age ≥ 75, previous stroke
transient ischemic attack (TIA) or Systemic Embolism (SE)
Symptomatic congestive heart failure or left ventricular dysfunction with left ventricular ejection fraction (LVEF) ≤ 40%
Diabetes mellitus or hypertension requiring pharmacological treatment

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00412984

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Locations

United States, Alabama
Cardiovascular Associates, Pc
Birmingham, Alabama, United States, 35209
Birmingham Heart Clinic P.C.
Birmingham, Alabama, United States, 35235
Alabama Internal Medicine Pc
Birmingham, Alabama, United States, 35235
Heart Center, Inc.
Huntsville, Alabama, United States, 35801
Mobile Heart Specialists, Pc
Mobile, Alabama, United States, 36608
Clara V. Massey, Md
Mobile, Alabama, United States, 36617
United States, Alaska
Alaska Heart Institute
Anchorage, Alaska, United States, 99508
United States, Arizona
Internal Medicine Physicians Associates, P.C.
Phoenix, Arizona, United States, 85006
Southern Arizona Va Health Care System
Tucson, Arizona, United States, 85723
Pima Research Foundation
Tucson, Arizona, United States, 85745
Southwest Heart
Tucson, Arizona, United States, 85710
United States, Arkansas
Dr. Rajesh Shroff
Hot Springs, Arkansas, United States, 71913
Mary K. Richards, Md Pa
Little Rock, Arkansas, United States, 72204
United States, California
Advanced Clinical Reserach Institute
Anaheim, California, United States, 92801
Act/Cardiovascular Research Institute
Beverly Hills, California, United States, 90210
Capitol Interventional Cardiology
Carmichael, California, United States, 95608
Escondido Cardiology Associates, Inc.
Escondido, California, United States, 92025
William D. Bowden, D.O.
Healdsburg, California, United States, 95448
La Mesa Cardiac Center, A Medical Group
Lamesa, California, United States, 91942
Va Greater Los Angeles Healthcare System
Los Angeles, California, United States, 90073
Coastal Cardiology
Mission Viejo, California, United States, 92691
Kenneth W. Carr Md
Oceanside, California, United States, 92056
Desert Med Grp Inc, Dba Desert Oasis Healthcare Med Group
Palm Springs, California, United States, 92262
Desert Cardiology Consultants Medical Group, Inc
Rancho Mirage, California, United States, 92270
Regional Cardiolody Associates
Sacramento, California, United States, 95819
Northern California Research
Sacramento, California, United States, 95821
Sacramento Heart And Vascular Medical Associates
Sacramento, California, United States, 95825
Arrhythmia Consultants Of The Central Coast Medical Group
Santa Barbara, California, United States, 93105
Northern California Medical Associates
Santa Rosa, California, United States, 95403
Progressive Clinical Research
Vista, California, United States, 92083
Cardivasclular Consultants Medical Group
Walnut Creek, California, United States, 94598
Shiva Heart Center Medical Group
Wildomar, California, United States, 92595
United States, Colorado
Electrophysiology Associates, Pc
Colorado Springs, Colorado, United States, 80910
Aurora Denver Cardiology Associates, P.C.
Denver, Colorado, United States, 80218
Denver Va Medical Center
Denver, Colorado, United States, 80220
New West Physicians Clinical Research
Golden, Colorado, United States, 80401
South Denver Cardiology Associates Pc
Littleton, Colorado, United States, 80120
United States, Connecticut
Bridgeport Hospital
Brideport, Connecticut, United States, 06610
Connecticut Clinical Research, Llc
Bridgeport, Connecticut, United States, 06606
Cardiology Associates Of New Haven,Pc
Guilford, Connecticut, United States, 06437
The William W. Backus Hospital
Norwich, Connecticut, United States, 06360
Stamford Therapeutics Consortium
Stamford, Connecticut, United States, 06905
Chase Medical Research, Llc
Waterbury, Connecticut, United States, 06708
United States, Delaware
Alfieri Cardiology
Newark, Delaware, United States, 19713
United States, District of Columbia
George Washington University Medical Faculty Associates
Washington, District of Columbia, United States, 20037
Washington Va Medical Center
Washington, District of Columbia, United States, 20422
United States, Florida
Medical Specialist Of The Palm Beach
Atlantis, Florida, United States, 33462
Miami International Cardiology Consultants
Aventura, Florida, United States, 33180
David Charles Mishkel, Md, Pa
Boca Raton, Florida, United States, 33431
The Heart & Vascular Institute Of Florida
Clearwater, Florida, United States, 33756
The Heart And Vascular Institute Of Florida
Clearwater, Florida, United States, 33756
Cardiovascular Specialist Of South Florida
Davie, Florida, United States, 33324
Daytona Heart Group
Daytona Beach, Florida, United States, 32114
Cardiology Associates Of Fort Lauderdale, P.A.
Fort Lauderdale, Florida, United States, 33308
Broward General Medical Center
Ft. Lauderdale, Florida, United States, 33316
Florida Heart Associates
Ft. Myers, Florida, United States, 33907
Florida Research Network, Llc
Gainesville, Florida, United States, 32605
Luis Tami, Md
Hollywood, Florida, United States, 33021
Healthworx
Hollywood, Florida, United States, 33021
Nature Coast Clinical Research
Inverness, Florida, United States, 34452
St. Vincent'S Ambulatory Care, Inc
Jacksonville, Florida, United States, 32204
Jacksonville Center For Clinical Research
Jacksonville, Florida, United States, 32216
Jacksonville Heart Center, Pa
Jacksonville, Florida, United States, 32207
St. Luke'S Cardiology
Jacksonville, Florida, United States, 32216
Jacksonville Cardiovascular Center
Jacksonville, Florida, United States, 32216
Jacksonville Heart Center, Pa
Jacksonville, Florida, United States, 32258
Jacksonville Heart Center, P.A.
Jacksonville Beach, Florida, United States, 32250
Cvms Research Institute, Llc
Jupiter, Florida, United States, 33458
Ricardo Bedoya, M.D.
Jupiter, Florida, United States, 33458
Melbourne Internal Medicine Associates
Melbourne, Florida, United States, 32901
Miami International Cardiology Consultants
Miami, Florida, United States, 33137
Physicians Regional Medical Group
Naples, Florida, United States, 34119
Florida Heart Group
Orlando, Florida, United States, 32803
Alpha Medical Research
Oviedo, Florida, United States, 32765
Cardiology Consultants
Pensacola, Florida, United States, 32501
Niranjan Seshadri, Md
Sarasota, Florida, United States, 34232
Heart & Vascular Center Research, Inc.
Sarasota, Florida, United States, 34239
The Heart And Vascular Institute Of Florida
St. Petersburg, Florida, United States, 33709
Research, Inc.
Vero Beach, Florida, United States, 32960
United States, Georgia
Cardiovascular Specialits, Pc
Atlanta, Georgia, United States, 30342
Augusta Cardiology Clinic, P.C.
Augusta, Georgia, United States, 30901
Columbus Cardiology Associates,Pc
Columbus, Georgia, United States, 31909
Georgia Heart Specialists, L.L.C.
Covington, Georgia, United States, 30014
Atlanta Institute For Medical Research, Inc
Decatur, Georgia, United States, 30030
Northeast Georgia Heart Center, Pc
Gainesville, Georgia, United States, 30501
Wellstar Cardiovascular Medicine, Pc
Marietta, Georgia, United States, 30060
United States, Illinois
Fox Valley Clinical Research Center, Llc
Aurora, Illinois, United States, 60504
Nmff
Chicago, Illinois, United States, 60611
Clinical Investigation Specialists, Inc
Gurnee, Illinois, United States, 60031
Loyola University Medical Center
Maywood, Illinois, United States, 60153
Illinois Heart & Lung Research Center, Sc
Normal, Illinois, United States, 61761
Cpt. James A Lovell Federal Health Care Center
North Chicago, Illinois, United States, 60064
United States, Indiana
Community Clinical Research Center
Anderson, Indiana, United States, 46011
Premier Healthcare, Llc
Bloomington, Indiana, United States, 47403
Elkhart Clinic, Llc
Elkhart, Indiana, United States, 46514
Fort Wayne Cardiology
Fort Wayne, Indiana, United States, 46805
Lutheran Medical Group, Llc
Fort Wayne, Indiana, United States, 46804
St Francis Medical Group - Indiana Heart Physicians
Indianapolis, Indiana, United States, 46237
The Care Group, Llc.
Indianapolis, Indiana, United States, 46290
Dali, Sammi
Michigan City, Indiana, United States, 46360
Cardiology Associates, Inc.
South Bend, Indiana, United States, 46601
United States, Iowa
Mcfarland Clinic Pc
Ames, Iowa, United States, 50010
United States, Kansas
Midwest Cardiology Associates , P.C.
Overland Park, Kansas, United States, 66209
United States, Kentucky
Central Cardiology Assoc.
Elizabethtown, Kentucky, United States, 42701
New Lexington Clinic, P.S.C.
Lexington, Kentucky, United States, 40504
Va Medical Center
Louisville, Kentucky, United States, 40202
Norton Cardiovascular Associates
Louisville, Kentucky, United States, 40205
Owensboro Heart & Vascular
Owensboro, Kentucky, United States, 42303
United States, Louisiana
Alexandria Cardiology Clinic
Alexandria, Louisiana, United States, 71301
Cardiovascular Institute Of The South
Houma, Louisiana, United States, 70360
Smith, Patel & Amkieh, Llc
Lacombe, Louisiana, United States, 70445
Imperial Calcasieu Medical Group, Llp
Lake Charles, Louisiana, United States, 70601
Cardiology Center, Llc
Marrero, Louisiana, United States, 70072
Cardiology Associates
Shreveport, Louisiana, United States, 71105
Medical Research Institute, Inc
Slidell, Louisiana, United States, 70458
Louisiana Heart Center
Slidell, Louisiana, United States, 70458
Ventura Cardio. Cond. Med. Group, Inc.
Ventura, Louisiana, United States, 93003
United States, Maine
Central Maine Heart & Vascular Institute
Lewiston, Maine, United States, 04240
United States, Maryland
Midatlantic Cardiovascular Associates, P.A.
Baltimore, Maryland, United States, 21218
Midatlantic Cardiovascular Associates, P.A.
Baltimore, Maryland, United States, 21204
Midatlantic Cardiovascular Associates, Pa
Baltimore, Maryland, United States, 21237
Franklin Square Hospital
Baltimore, Maryland, United States, 21237
Johns Hopkins Bayview Medical Center
Baltimore, Maryland, United States, 21224
Midatlantic Cardiovascular Associates, Pa
Baltimore, Maryland, United States, 21208
Midatlantic Cardiovascular Associates, Pa
Bel Air, Maryland, United States, 21014
Cardiovascular Specialists Of Central Maryland, P.A.
Columbia, Maryland, United States, 21044
Clinical Associates Research
Reisterstown, Maryland, United States, 21136
Midatlantic Cardiovascular Associates, Pa
Westminster, Maryland, United States, 21157
United States, Massachusetts
Burlington Medical Associates
Billerica, Massachusetts, United States, 01821
Caritas St. Elizabeth'S Medical Center
Boston, Massachusetts, United States, 02135
Lahey Clinic Medical Center
Burlington, Massachusetts, United States, 01805
Neccr Internal Medicine & Cardiology Associates,Llc
Fall River, Massachusetts, United States, 02720
Pentucket Medical Associates
Haverhill, Massachusetts, United States, 01830
Charles River Medical Associates
Natick, Massachusetts, United States, 01760
United States, Michigan
Great Lakes Heart Center Of Alpena
Alpena, Michigan, United States, 49707
Henry Ford Hospital
Detroit, Michigan, United States, 48202
Thoracic And Cardiovascular Healthcare Foundation
Lansing, Michigan, United States, 48910
Advanced Cardiovascular Health Specialists, Pc
Livonia, Michigan, United States, 48154
Michigan Heart And Vascular Specialists
Petoskey, Michigan, United States, 49770
William Beaumont Hospital
Royal Oak, Michigan, United States, 48073
Michigan Heart, P.C.
Ypsilanti, Michigan, United States, 48197
United States, Minnesota
University Of Minnesota
Minneapolis, Minnesota, United States, 55455
Minneapolis Va Medical Center
Minneapolis, Minnesota, United States, 55417
North Memorial Health Care
Robbinsdale, Minnesota, United States, 55422
United States, Mississippi
Olive Branch Family Medical Center
Olive Branch, Mississippi, United States, 38654
Tupelo Neurology Clinic, Pa
Tupelo, Mississippi, United States, 38801
United States, Missouri
University Of Missouri
Columbia, Missouri, United States, 65212
Saint Luke'S Lipid And Diabetes Research Center
Kansas City, Missouri, United States, 64111
Truman Medical Center
Kansas City, Missouri, United States, 64108
United States, Nebraska
Internal Medical Associates Of Grand Island, P.C
Grand Island, Nebraska, United States, 68803
Nebraska Heart Institute
Hastings, Nebraska, United States, 68901
United States, Nevada
Va Southern Nevada Healthcare System
Las Vegas, Nevada, United States, 89106
United States, New Jersey
Comprehensive Clinical Research
Berlin, New Jersey, United States, 08009
Cardiovascular Associates Of The Delware Valley, P.A.
Elmer, New Jersey, United States, 08318
Cardiovascular Associates Of The Delaware Valley, P.A.
Haddon Heights, New Jersey, United States, 08035
Princeton Medical Institute
Princeton, New Jersey, United States, 08540
Cardio Assoc Of Del Val, P.A.
Sewell, New Jersey, United States, 08080
Central New Jersey Cardiology
South Plainfield, New Jersey, United States, 07080
United States, New Mexico
Abq Health Partners, Llc
Albuquerque, New Mexico, United States, 87012
University Of New Mexico/University Hospital
Albuquerque, New Mexico, United States, 87131
United States, New York
Albany Assoc. In Cardiology
Albany, New York, United States, 12205
Cardiology Associates, Pc
Binghamton, New York, United States, 13905
Bruce L. Platt, Md
Buffalo, New York, United States, 14215
Buffalo Heart Group, Llp
Buffalo, New York, United States, 14215
Heart Care Center, P.C.
East Syracuse, New York, United States, 13057
Huntington Hospital
Huntington, New York, United States, 11743
Sjh Cardiology Associates
Liverpool, New York, United States, 13088
Long Island Heart Associates
Mineola, New York, United States, 11501
Saratoga Cardiology Associates, Pc
Saratoga Springs, New York, United States, 12866
Suburban Cardiology
Williamsville, New York, United States, 14221
Office Of Dr. Kozinn
Williamsville, New York, United States, 14221
United States, North Carolina
Asheville Cardiology Associates
Asheville, North Carolina, United States, 28803
Kernodle Clinic, Inc.
Burlington, North Carolina, United States, 27215
Carolina Cardiology Associates, Pa
High Point, North Carolina, United States, 27262
Pinehurst Medical Center, Inc
Pinehurst, North Carolina, United States, 28374
United States, North Dakota
Lillestol Research Llc
Fargo, North Dakota, United States, 58103
United States, Ohio
Akron Cardiology Consultants
Akron, Ohio, United States, 44304
Christopher M. Johnson, D.O.
Bucyrus, Ohio, United States, 44820
Community Health Care, Inc.
Canal Fulton, Ohio, United States, 44614
Cardiology Associates
Canton, Ohio, United States, 44710
The Carl & Edyth Lindner Center For R&E At The Christ Hosp
Cincinnati, Ohio, United States, 45219
Toledo Cardiology Consultants
Toledo, Ohio, United States, 43608
Family Practice Center Of Wadsworth, Inc.
Wadsworth, Ohio, United States, 44281
United States, Oklahoma
Jack C. Va Medical Center
Muskogee, Oklahoma, United States, 74401
Plaza Medical Group, Pc
Oklahoma City, Oklahoma, United States, 73112
Oklahoma Heart Hospital Physicians
Oklahoma City, Oklahoma, United States, 73120
Cor Clinical Research, Llc
Oklahoma City, Oklahoma, United States, 73103
South Oklahoma Heart Research
Oklahoma City, Oklahoma, United States, 73135
Eminence Research, Llc
Oklahoma City, Oklahoma, United States, 73139
University Of Oklahoma Health Sciences Center
Oklahoma City, Oklahoma, United States, 73104
Castlerock Clinical Research Consultants, Llc
Tulsa, Oklahoma, United States, 74136
United States, Oregon
St. Charles Health System, Inc.
Bend, Oregon, United States, 97701
Oregon Medical Group - Clinical Research
Eugene, Oregon, United States, 97401
Hillsboro Cardiology Pc
Hillsboro, Oregon, United States, 97123
Rogue Valley Physicians - Clinical Research Group
Medford, Oregon, United States, 97504
United States, Pennsylvania
Abington Medical Specialists
Abington, Pennsylvania, United States, 19001
Blair Medical Associates, Inc.
Altoona, Pennsylvania, United States, 16602
Heritage Cardiology Assoc.
Camp Hill, Pennsylvania, United States, 17011
Central Bucks Cardiology
Doylestown, Pennsylvania, United States, 18901
Internal Medicine And Lipid Mgmt.
Erie, Pennsylvania, United States, 16509
Kandra, Fierer, Kuskin Associates
Harrisburg, Pennsylvania, United States, 17112
Pivotal Clinical Research, Llc
Hatfield, Pennsylvania, United States, 19440
Lycoming Internal Medicine Inc.
Jerssey Shore, Pennsylvania, United States, 17740
Guthrie Clinic Ltd.
Sayre, Pennsylvania, United States, 18840
Preferred Primary Care Physicians
Uniontown, Pennsylvania, United States, 15401
West Chester Cardiology, Pc
West Chester, Pennsylvania, United States, 19380
Cardiology Consultants Of Philadelphia
Yardley, Pennsylvania, United States, 19067
United States, Rhode Island
Rhode Island Hospital
Providence, Rhode Island, United States, 02903
United States, South Carolina
Southeastern Research Associates, Inc
Anderson, South Carolina, United States, 29621
Lowcountry Medical Group
Beaufort, South Carolina, United States, 29906
Medical University Of South Carolina
Charleston, South Carolina, United States, 29425
Columbia Heart Clinic
Columbia, South Carolina, United States, 29203
Upstate Cardiology
Greenville, South Carolina, United States, 29607
Internal Medicine Of Greer
Greer, South Carolina, United States, 29650
Palmetto Nephrology Pa
Orangeburg, South Carolina, United States, 29118
S. Carolina Pharmaceutical Research
Spartanburg, South Carolina, United States, 29303
United States, South Dakota
Avera Medical Associates Clinic
Peirre, South Dakota, United States, 57501
United States, Tennessee
Holston Medical Group
Bristol, Tennessee, United States, 37620
Holston Medical Group
Kingsport, Tennessee, United States, 37660
Knoxville Heart Group
Knoxville, Tennessee, United States, 37916
Volunteer Research Group
Knoxville, Tennessee, United States, 37920
Tennessee Center For Clinical Trials
Tullahoma, Tennessee, United States, 37388
United States, Texas
Amarillo Heart Clinical Research Institute Inc.
Amarillo, Texas, United States, 79106
Corsicana Medical Research, Pllc
Corsicana, Texas, United States, 75110
Soltero Cardiovascular Research Center
Dallas, Texas, United States, 75226
Heartplace
Dallas, Texas, United States, 75230
Heart Center Of North Texas
Ft. Worth, Texas, United States, 76104
The Methodist Hospital Neurology Institute
Houston, Texas, United States, 77030
Center For Atrial Fibrillation
Houston, Texas, United States, 77030
The University Of Texas Md Anderson Cancer Center
Houston, Texas, United States, 77030
Northwest Houston Cardiology, Pa
Houston, Texas, United States, 77070
Woodlands North Houston Heart Center
Houston, Texas, United States, 77090
Francisco R. Maislos
Houston, Texas, United States, 77074
The Methodist Hospital
Houston, Texas, United States, 77030
Regional Medical Center And Diagnostic Clinics
Humble, Texas, United States, 77338
Wilford Hall Medical Center
Lackland Afb, Texas, United States, 78236
Dcol Center For Clinical Research
Longview, Texas, United States, 75605
North Dallas Research Associates
Mckinney, Texas, United States, 75069
Legacy Heart Center
Plano, Texas, United States, 75024
North Texas Medical Research
Plano, Texas, United States, 75093
Bhs Specialty Network, Inc
San Antonio, Texas, United States, 78217
Star Clinical Trails
San Antonio, Texas, United States, 78229
Covenant Clinical Research, Pa
San Antonio, Texas, United States, 78229
Edward Balli, Md, Pa
Seguin, Texas, United States, 78155
Northwest Heart Center
Tomball, Texas, United States, 77375
The Univ. Of Texas Health Science Ctr. At Tyler
Tyler, Texas, United States, 75708
Tyler Cardiovascular Consultants
Tyler, Texas, United States, 75701
United States, Utah
Utah Cardiology P.C
Layton, Utah, United States, 84041
United States, Virginia
Sentara York Clinical Research
Norfolk, Virginia, United States, 23510
Medical Research Initiatives
Richmond, Virginia, United States, 23220
Roanoke Heart Institute, Plc
Roanoke, Virginia, United States, 24014
Cardiovascular Associates
Virginia Beach, Virginia, United States, 23454
United States, Washington
Daniel William Gottlieb, Md
Burien, Washington, United States, 98166
Rockwood Clinic Research Cent.
Spokane, Washington, United States, 99202
Walla Walla Clinic
Walla Walla, Washington, United States, 99362
United States, West Virginia
Lynn N. Smith, Md
Lewisburg, West Virginia, United States, 24901
United States, Wisconsin
Cardiology Associates Of Green Bay Ltd-Bellin Hospital
Green Bay, Wisconsin, United States, 54301
St.Mary'S Hospital
Madison, Wisconsin, United States, 53715
Aurora Health Care
Milwaukee, Wisconsin, United States, 53215
Medical College Of Wisconsin
Milwaukee, Wisconsin, United States, 53226
Cardiology Assc. Of Waukesha
Waukesha, Wisconsin, United States, 53188
Argentina
Local Institution
Adrogue, Buenos Aires, Argentina, 1846
Local Institution
Bahia Blanca, Buenos Aires, Argentina, B8000FTD
Local Institution
Ciudad Autonoma, Buenos Aires, Argentina, C1426 EGR
Local Institution
Ciudad Autonoma, Buenos Aires, Argentina, CP1425AWC
Local Institution
Ciudad Autonoma, Buenos Aires, Argentina, 1128
Local Institution
Ciudad Autonoma De, Buenos Aires, Argentina, 1180
Local Institution
Ciudad Autonoma De Buenos Aire, Buenos Aires, Argentina, CI094AAD
Local Institution
Coronel Suarez, Buenos Aires, Argentina, B7540GHD
Local Institution
Haedo, Buenos Aires, Argentina, B1706AJU
Local Institution
Junin, Buenos Aires, Argentina, 6000
Local Institution
La Plata, Buenos Aires, Argentina, B1900AXI
Local Institution
La Plata, Buenos Aires, Argentina, 1902
Local Institution
La Plata, Buenos Aires, Argentina, 1900
Local Institution
Mar Del Plata, Buenos Aires, Argentina, 7600
Local Institution
Merlo, Buenos Aires, Argentina, 1722
Local Institution
Olivos, Buenos Aires, Argentina, 1602
Local Institution
Quilmes, Buenos Aires, Argentina, 1878
Local Institution
Ramos Mejia, Buenos Aires, Argentina, B1704ESN
Local Institution
Ramos Mejia, Buenos Aires, Argentina, 1706
Local Institution
San Justo, Buenos Aires, Argentina, 1754
Local Institution
San Martin, Buenos Aires, Argentina, 1650
Local Institution
San Nicolas, Buenos Aires, Argentina, 2900
Local Institution
Zarate, Buenos Aires, Argentina, 2800
Local Institution
Cordoba, Provincia De Cordoba, Argentina, 5000
Local Institution
Cipolletti, Rio Negro, Argentina, 8324
Local Institution
Rosario, Santa Fe, Argentina, S2001ODA
Local Institution
Rosario, Santa Fe, Argentina, 2000
Local Institution
Rosario, Santa Fe, Argentina, S2000 CVD
Local Institution
Rosario, Santa Fe, Argentina, S2000CVD
Local Institution
San Miquel De Tucuman, Tucuman, Argentina, 4000
Local Institution
Buenos Aires, Argentina, 1280
Local Institution
Buenos Aires, Argentina, C1426ANZ
Local Institution
Buenos Aires, Argentina, 1119
Local Institution
Buenos Aires, Argentina, 1181
Local Institution
Cordoba, Argentina, X5000EPU
Local Institution
Cordoba, Argentina, X5003DCE
Local Institution
Cordoba, Argentina, 5000
Local Institution
Cordoba, Argentina, X5008KKF
Local Institution
Salta, Argentina, 4400
Local Institution
Santa Fe, Argentina, 3000
Local Institution
Tucuman, Argentina, T4000NIL
Australia, New South Wales
Local Institution
Coffs Harbour, New South Wales, Australia, 2450
Local Institution
Concord, New South Wales, Australia, 2139
Local Institution
Gosford, New South Wales, Australia, 2250
Local Institution
Kogarah, New South Wales, Australia, 2217
Local Institution
Miranda, New South Wales, Australia, 2228
Australia, Queensland
Local Institution
Auchenflower, Queensland, Australia, 4066
Local Institution
Brisbane, Queensland, Australia, 4032
Local Institution
Caboolture, Queensland, Australia, 4510
Local Institution
Herston, Queensland, Australia, 4029
Local Institution
Kippa Ring, Queensland, Australia, 4021
Local Institution
Nambour, Queensland, Australia, 4560
Local Institution
Sherwood, Queensland, Australia, 4075
Australia, South Australia
Local Institution
Adelaide, South Australia, Australia, SA 5000
Local Institution
Ashford, South Australia, Australia, 5035
Local Institution
Bedford Park, South Australia, Australia, 5042
Local Institution
Woodville, South Australia, Australia, 5011
Australia, Victoria
Local Institution
Box Hill, Victoria, Australia, 3128
Local Institution
Dandenong, Victoria, Australia, 3175
Local Institution
Geelong, Victoria, Australia, 3220
Australia, Western Australia
Local Institution
Fremantle, Western Australia, Australia, 6160
Local Institution
Joondalup, Western Australia, Australia, 6027
Austria
Local Institution
Graz, Austria, 8036
Local Institution
Oberpullendorf, Austria, 7350
Local Institution
Vienna, Austria, 1160
Belgium
Local Institution
Aalst, Belgium, 9300
Local Institution
Antwerpen, Belgium, 2020
Local Institution
Antwerpen, Belgium, 2060
Local Institution
Arlon, Belgium, 6700
Local Institution
Brugge, Belgium, 8000
Local Institution
Brussels, Belgium, 1090
Local Institution
Genk, Belgium, 3600
Local Institution
Gent, Belgium, 9000
Local Institution
Gilly, Belgium, 6060
Local Institution
Hasselt, Belgium, 3500
Local Institution
Huy, Belgium, 4500
Local Institution
Kortrijk, Belgium, 8500
Local Institution
Menen, Belgium, 8930
Local Institution
Mol, Belgium, 2400
Local Institution
Montegnee, Belgium, 4420
Local Institution
Verviers, Belgium, 4800
Local Institution
Woluwe- Saint Lambert, Belgium, 1200
Local Institution
Yvoir, Belgium, 5530
Brazil
Local Institution
Salvador, Bahia, Brazil, 40144
Local Institution
Salvador, Bahia, Brazil, 41810
Local Institution
Belo Horzonte, Minas Gerais, Brazil, 30150
Local Institution
Juiz De Fora, Minas Gerais, Brazil, 36021
Local Institution
Uberaba, Minas Gerais, Brazil, 38056 055
Local Institution
Uberlandia, Minas Gerais, Brazil, 38400
Local Institution
Campina Grande Do Sul, Parana, Brazil, 83430
Local Institution
Curitiba, Parana, Brazil, 80010
Local Institution
Curitiba, Parana, Brazil, 80730
Local Institution
Londrina, Parana, Brazil, 86010
Local Institution
Belem, Para, Brazil, 66087
Local Institution
Natal, Rio Grande Do Norte, Brazil, 59020
Local Institution
Porte Alegre, Rio Grande Do Sul, Brazil, 90610
Local Institution
Porte Alegre, Rio Grande Do Sul, Brazil, 90880480
Local Institution
Porto Alegre, Rio Grande Do Sul, Brazil, 91350
Local Institution
Porto Alegre, Rio Grande Do Sul, Brazil, 90035
Local Institution
Porto Alegre, Rio Grande Do Sul, Brazil, 90020
Local Institution
Porto Alegre, Rio Grande Do Sul, Brazil, 90620
Local Institution
Blumenau, Santa Catarina, Brazil, 89010
Local Institution
Sao Jose, Santa Catarina, Brazil, 88103
Local Institution
Botucatu, Sao Paulo, Brazil, 18618
Local Institution
Campinas, Sao Paulo, Brazil, 13059
Local Institution
Marilia, Sao Paulo, Brazil, 17515
Local Institution
Marilia, Sao Paulo, Brazil, 17519
Local Institution
San Jose Do Rio Preto, Sao Paulo, Brazil, 15090
Local Institution
Santo Andre, Sao Paulo, Brazil, 09190
Local Institution
Sao Jose Do Rio Preto, Sao Paulo, Brazil, 15015
Local Institution
Rio De Janeiro, Brazil, 22251
Local Institution
Rio De Janeiro, Brazil, 20551
Local Institution
Sao Paulo, Brazil, 04038
Local Institution
Sao Paulo, Brazil, 08270
Local Institution
Sao Paulo, Brazil, 04012
Local Institution
Sao Paulo, Brazil, 01221
Local Institution
Sao Paulo, Brazil, 01323
Local Institution
Sao Paulo, Brazil, 04024
Local Institution
Sao Paulo, Brazil, 01322
Canada, Alberta
Local Institution
Calgary, Alberta, Canada, T2E 7C5
Local Institution
Edmonton, Alberta, Canada, T6G 2B7
Local Institution
Edmonton, Alberta, Canada, T56-3NJ
Local Institution
Edmonton, Alberta, Canada, TSA 4L8
Canada, British Columbia
Local Institution
Burnaby, British Columbia, Canada, V5G 1T4
Local Institution
Nanaimo, British Columbia, Canada, V9R 3G9
Local Institution
New Westminster, British Columbia, Canada, V3L 3W4
Local Institution
North Vancouver, British Columbia, Canada, V7N 4M2
Local Institution
Victoria, British Columbia, Canada, V8R 4R2
Canada, Manitoba
Local Institution
Winnipeg, Manitoba, Canada, R2V 4W3
Canada, New Brunswick
Local Institution
Bathurst, New Brunswick, Canada, E2A 4X7
Canada, Newfoundland and Labrador
Local Institution
Mount Pearl, Newfoundland and Labrador, Canada, A1N 1W7
Local Institution
St Johns, Newfoundland and Labrador, Canada, A1B 3V6
Local Institution
St. John'S, Newfoundland and Labrador, Canada, A1A 3R5
Local Institution
St. John'S, Newfoundland and Labrador, Canada, A1E 2C2
Canada, Ontario
Local Institution
Brampton, Ontario, Canada, L6Z 4N5
Local Institution
Burlington, Ontario, Canada, L7M 4Y1
Local Institution
Cambridge, Ontario, Canada, N1R 7R1
Local Institution
Cambridge, Ontario, Canada, N1R 6V6
Local Institution
Hamilton, Ontario, Canada, L8L 2X2
Local Institution
London, Ontario, Canada, N6G 2V2
Local Institution
Mississauga, Ontario, Canada, L5B 4A2
Local Institution
Newmarket, Ontario, Canada, L3Y 5G8
Local Institution
Newmarket, Ontario, Canada, L3Y 8C3
Local Institution
Niagara Falls, Ontario, Canada, L2E 7H1
Local Institution
North Bay, Ontario, Canada, P1B 2H3
Local Institution
Oshawa, Ontario, Canada, L1J 2J9
Local Institution
Oshawa, Ontario, Canada, L1J 2K1
Local Institution
Ottawa, Ontario, Canada, K1Y 4E9
Local Institution
Ottawa, Ontario, Canada, K1Y 4W7
Local Institution
Sarnia, Ontario, Canada, N7T 4X3
Local Institution
Scarborough, Ontario, Canada, M1B 5N1
Local Institution
Sudbury, Ontario, Canada, P3E 2N8
Local Institution
Sudbury, Ontario, Canada, P3E 3B8
Local Institution
Sudbury, Ontario, Canada, P3C 5K7
Local Institution
Toronto, Ontario, Canada, M9W 4L6
Local Institution
Toronto, Ontario, Canada, M5B 1W8
Local Institution
Weston, Ontario, Canada, M9N 1W4
Canada, Prince Edward Island
Local Institution
Charlottetown, Prince Edward Island, Canada, C1A 5Y9
Canada, Quebec
Local Institution
Drummondville, Quebec, Canada, J2B 7T1
Local Institution
Greenfield Park, Quebec, Canada, J4V 2G8
Local Institution
Lachine, Quebec, Canada, H8S 2E4
Local Institution
Levis, Quebec, Canada, G6V 4Z5
Local Institution
Longueuil, Quebec, Canada, J4N 0C9
Local Institution
Longueuil, Quebec, Canada, J4K 1C8
Local Institution
Longueuil, Quebec, Canada, J4N 1C2
Local Institution
Montreal, Quebec, Canada, H1T 1C8
Local Institution
Montreal, Quebec, Canada, H3A 1A1
Local Institution
Montreal, Quebec, Canada, H2W 1T8
Local Institution
Montreal, Quebec, Canada, H3T 1E2
Local Institution
Pointe- Claire, Quebec, Canada, H9R 3J1
Local Institution
St-Lambert, Quebec, Canada, J4P 2H4
Local Institution
Ste-Foy, Quebec, Canada, G1W 4R4
Canada, Saskatchewan
Local Institution
Saskatoon, Saskatchewan, Canada, S7L OY7
Canada
Local Institution
Quebec, Canada, G1J 1Z6
Chile
Local Institution
Osorno, Los Lagos, Chile, 5311089
Local Institution
Osorno, Los Lagos, Chile, 5311523
Local Institution
Santiago, Metropolitana, Chile, 7500922
Local Institution
Santiago, Metropolitana, Chile, 8330074
Local Institution
Santiago, Metropolitana, Chile, 7500520
Local Institution
Temuco, Region De La Araucania, Chile, 4781156
Local Institution
Temuco, Valparaiso, Chile, 4781173
Local Institution
Vina Del Mar, Valparaiso, Chile, 2570017
China, Beijing
Local Institution
Beijing, Beijing, China, 100101
Local Institution
Beijing, Beijing, China, 100001
Local Institution
Beijing, Beijing, China, 100088
Local Institution
Beijing, Beijing, China, 100020
Local Institution
Beijing, Beijing, China, 100050
China, Gansu
Local Institution
Lanzhou, Gansu, China, 730000
Local Institution
Lanzhou, Gansu, China, 730030
China, Guangdong
Local Institution
Guangzhou, Guangdong, China, 510120
Local Institution
Guangzhou, Guangdong, China, 510080
China, Hebei
Local Institution
Shijiazhuang, Hebei, China, 050000
China, Heilongjiang
Local Institution
Daqing, Heilongjiang, China, 163001
Local Institution
Haerbin, Heilongjiang, China, 150001
Local Institution
Haerbin, Heilongjiang, China, 150086
China, Hubei
Local Institution
Wuhan, Hubei, China, 430060
China, Hunan
Local Institution
Changsha, Hunan, China, 410000
China, Jiangsu
Local Institution
Hangzhou, Jiangsu, China, 310009
Local Institution
Nanjing, Jiangsu, China, 210029
China, Liaoning
Local Institution
Dalian, Liaoning, China, 116021
Local Institution
Dalian, Liaoning, China, 116011
Local Institution
Dalian, Liaoning, China, 116027
Local Institution
Shenyang, Liaoning, China, 110016
Local Institution
Shenyang, Liaoning, China, 110003
China, Shandong
Local Institution
Jinan, Shandong, China, 250033
Local Institution
Jinan, Shandong, China, 250012
Local Institution
Qingdao, Shandong, China, 266011
China, Shanghai
Local Institution
Shanghai, Shanghai, China, 200011
Local Institution
Shanghai, Shanghai, China, 200031
Local Institution
Shanghai, Shanghai, China, 200233
Local Institution
Shanghai, Shanghai, China, 200025
Local Institution
Shanghai, Shanghai, China, 100037
Local Institution
Shanghai, Shanghai, China, 200003
Local Institution
Shanghai, Shanghai, China, 200433
Local Institution
Shanghai, Shanghai, China, 200080
China, Sichuan
Local Institution
Chengdu, Sichuan, China, 610041
Local Institution
Chongqing, Sichuan, China, 400010
China, Zhejiang
Local Institution
Hangzhou, Zhejiang, China, 310009
Colombia
Local Institution
Medellin, Antioquia, Colombia
Local Institution
Barranquilla, Colombia, -----
Local Institution
Bogota, Colombia
Local Institution
Bogota, Colombia, 000
Local Institution
Cali, Colombia, -----
Local Institution
Medellin, Colombia
Czech Republic
Local Institution
Boskovice, Czech Republic, 680 21
Local Institution
Brno, Czech Republic, 625 00
Local Institution
Brno-Malomerice, Czech Republic, 614 00
Local Institution
Ivancice, Czech Republic, 664 91
Local Institution
Kladno, Czech Republic, 272 59
Local Institution
Litomysl, Czech Republic, 570 14
Local Institution
Mestec Kralove, Czech Republic, 289 03
Local Institution
Ostrava, Czech Republic, 70852
Local Institution
Prague 13, Czech Republic, 158 00
Local Institution
Prague 2, Czech Republic, 128 08
Local Institution
Pribram, Czech Republic, 261 01
Local Institution
Usti Nad Orlici, Czech Republic, 562 18
Denmark
Local Institution
Arhus C, Denmark, 8000
Local Institution
Esbjerg, Denmark, 6700
Local Institution
Frederiksberg, Denmark, 2000
Local Institution
Frederikssund, Denmark, 3600
Local Institution
Gentofte, Denmark, 2900
Local Institution
Haderslev, Denmark, 6100
Local Institution
Hellerup, Denmark, 2900
Local Institution
Herlev, Denmark, 2730
Local Institution
Herning, Denmark, 7400
Local Institution
Hillerod, Denmark, 3400
Local Institution
Hvidovre, Denmark, 2650
Local Institution
Kobenhavn, Denmark, 2100
Local Institution
Kolding, Denmark, 6000
Local Institution
Odense, Denmark, 5000
Local Institution
Silkeborg, Denmark, 8600
Local Institution
Slagelse, Denmark, 4200
Local Institution
Svendborg, Denmark, 5700
Finland
Local Institution
Helsinki, Finland, 00280
Local Institution
Hus, Finland, 00029
Local Institution
Jyvaskyla, Finland, 40100
Local Institution
Kemi, Finland, 94100
Local Institution
Oulu, Finland, 90100
Local Institution
Pori, Finland, 28120
Local Institution
Tampere, Finland, 33100
France
Local Institution
Amiens Cedex 1, France, 80054
Local Institution
Bordeaux Cedex, France, 33075
Local Institution
Brest, France, 29609
Local Institution
Grenoble Cedex 09, France, 38043
Local Institution
La Seyne Sur Mer, France, 83500
Local Institution
Paris Cedex 18, France, 75018
Local Institution
Six Fours Les Plages, France, 83140
Germany
Local Institution
Aachen, Germany, 52074
Local Institution
Bad Krozingen, Germany, 79189
Local Institution
Bad Neustadt/ Salle, Germany, 97616
Local Institution
Bad Oeynhausen, Germany, 32545
Local Institution
Berlin, Germany, 12043
Local Institution
Berlin, Germany, 14050
Local Institution
Berlin, Germany, 10787
Local Institution
Berlin, Germany, 13353
Local Institution
Berlin, Germany, 10789
Local Institution
Berlin-Kopenick, Germany, 12559
Local Institution
Betzdorf, Germany, 57518
Local Institution
Bochum, Germany, 44789
Local Institution
Bochum, Germany, 44791
Local Institution
Bonn, Germany, 53127
Local Institution
Coburg, Germany, 96450
Local Institution
Dillingen, Germany, 66763
Local Institution
Dresden, Germany, 01099
Local Institution
Duisburg, Germany, 47139
Local Institution
Essen, Germany, 45122
Local Institution
Frankfurt Am Main, Germany, 60594
Local Institution
Gottingen, Germany, 37075
Local Institution
Halle/Saale, Germany, 06120
Local Institution
Hannover, Germany, 30625
Local Institution
Heidelberg, Germany, 69120
Local Institution
Heidelberg, Germany, 69115
Local Institution
Kassel, Germany, 34121
Local Institution
Lahr, Germany, 77933
Local Institution
Ludwigshafen, Germany, 67073
Local Institution
Mannheim, Germany, 68167
Local Institution
Marburg, Germany, 35043
Local Institution
Munchen, Germany, 81545
Local Institution
Munchen, Germany, 81675
Local Institution
Munchen, Germany, 80636
Local Institution
Osnabruck, Germany, 49076
Local Institution
Regensburg, Germany, 93053
Local Institution
Riesa, Germany, D-01587
Local Institution
Rostiock, Germany, 18057
Local Institution
Trier, Germany, 54292
Local Institution
Waren, Germany, 17192
Local Institution
Witten, Germany, 58455
Local Institution
Wolmirstedt, Germany, 39326
Local Institution
Worms, Germany, 67550
Hong Kong
Local Institution
Hong Kong, Hong Kong
Local Institution
Shatin, Hong Kong
Hungary
Local Institution
Budapest, Hungary, 1096
Local Institution
Budapest, Hungary, 1085
Local Institution
Budapest, Hungary, 1125
Local Institution
Budapest, Hungary, 1023
Local Institution
Budapest, Hungary, 1032
Local Institution
Debrecen, Hungary, 4032
Local Institution
Dunaujvaros, Hungary, 2400
Local Institution
Gyor, Hungary, 9023
Local Institution
Gyula, Hungary, 5700
Local Institution
Hodmezovasarhely, Hungary, 6800
Local Institution
Komarom, Hungary, 2921
Local Institution
Mosonmagyarovar, Hungary, 9200
Local Institution
Oroshaza, Hungary, 5900
Local Institution
Pecs, Hungary, 7624
Local Institution
Siofok, Hungary, 8600
Local Institution
Sopron, Hungary, 9400
Local Institution
Szentes, Hungary, 6600
Local Institution
Zalaegerszeg, Hungary, 8900
India
Local Institution
Visakhapatnam, Andhra Pradesh, India, 530003
Local Institution
Visakhapatnam, Andhrapradesh, India, 530002
Local Institution
Hyderabad, Andra Pradesh, India, 500004
Local Institution
Ahmedabad, Gujarat, India, 380060
Local Institution
Vadodara, Gujarat, India, 390007
Local Institution
Bangalore, Karnataka, India, 560094
Local Institution
Bangalore, Karnataka, India, 5600034
Local Institution
Bangalore, Karnataka, India, 560054
Local Institution
Mysore, Karnataka, India, 570004
Local Institution
Calicut, Kerela, India, 673 004
Local Institution
Pune, Maharashta, India, 411011
Local Institution
Nagpur, Maharashtra, India, 440010
Local Institution
Nagpur, Maharashtra, India, 440012
Local Institution
Pune, Maharashtra, India, 421006
Local Institution
Pune, Maharashtra, India, 411001
Local Institution
Jalandhar, Punjab, India, 144008
Local Institution
Bikaner, Rajasthan, India, 334003
Local Institution
Lucknow, Uttar Pradesh, India, 226003
Local Institution
Ahmedabad, India, 380014
Local Institution
Annamalainagar, India, 608002
Local Institution
Bangalore, India, 560052
Local Institution
Chennai, India, 600006
Local Institution
Hyderabad, India, 500044
Local Institution
Hyderabad, India, 500001
Local Institution
Indore, India, 452001
Local Institution
Indore, India, 452014
Local Institution
Kolkata, India, 700054
Local Institution
Kottayam, India, 686016
Local Institution
Lucknow, India, 226003
Local Institution
Mumbai Naka, India, 422005
Local Institution
Nashik, India, 422002
Local Institution
New Delhi, India, 110060
Local Institution
New Delhi, India, 110025
Local Institution
Pune, India, 411001
Local Institution
Pune, India, 411004
Local Institution
Thrissur, India, 680002
Local Institution
Vijayawada, India, 520008
Israel
Local Institution
Afula, Israel, 18101
Local Institution
Ashkelon, Israel, 78306
Local Institution
Givatayim, Israel, 53583
Local Institution
Hadera, Israel, 38100
Local Institution
Haifa, Israel, 31096
Local Institution
Haifa, Israel, 34362
Local Institution
Holon, Israel, 58100
Local Institution
Jerusalem, Israel, 91240
Local Institution
Jerusalem, Israel, 91120
Local Institution
Kfar-Saba, Israel, 44281
Local Institution
Nazareth, Israel, 16000
Local Institution
Nazareth, Israel, 16100
Local Institution
Petach-Tikva, Israel, 49100
Local Institution
Safed, Israel, 13100
Local Institution
Tel Aviv, Israel, 64239
Italy
Local Institution
Lido Di Camaiore, Lucca, Italy, 55043
Local Institution
Ascoli Piceno, Italy, 63100
Local Institution
Campobasso, Italy, 86100
Local Institution
Chieti, Italy, 66013
Local Institution
Cremona, Italy, 26100
Local Institution
Fidenza (Pr), Italy, 43036
Local Institution
Genova, Italy, 16132
Local Institution
Isernia, Italy, 86170
Local Institution
Livorno, Italy, 57100
Local Institution
Milano, Italy, 20132
Local Institution
Napoli, Italy, 80131
Local Institution
Palermo, Italy, 90127
Local Institution
Reggio Emilia, Italy, 42100
Local Institution
Roma, Italy, 00168
Local Institution
San Daniele De Friuli, Italy, 33038
Local Institution
Torino, Italy, 10153
Local Institution
Vittorio Veneto (Tv), Italy, 31029
Japan
Local Institution
Itoshima City, Fukuoka, Japan, 819-1104
Local Institution
Kurume, Fukuoka, Japan, 8390863
Local Institution
Ohkawa-City, Fukuoka, Japan, 8310016
Local Institution
Shirakawa City, Fukushima, Japan, 961-0005
Local Institution
Takasaki City, Gunma, Japan, 3700829
Local Institution
Asahikawa-Shi, Hokkaido, Japan, 0788214
Local Institution
Katou-Gun, Hokkaido, Japan, 0800111
Local Institution
Sapporo-Shi, Hokkaido, Japan, 0028043
Local Institution
Tomakomai-Shi, Hokkaido, Japan, 002-8043
Local Institution
Yubari, Hokkaido, Japan, 0680402
Local Institution
Kobe, Hyogo, Japan, 6540026
Local Institution
Izumi City, Kagoshima Prefecture, Japan, 8990131
Local Institution
Isehara, Kanagawa, Japan, 2591193
Local Institution
Yokohama, Kanagawa, Japan, 2458575
Local Institution
Yokohama City, Kanagawa, Japan, 2278501
Local Institution
Yokosuka, Kanagawa, Japan, 2388567
Local Institution
Sendai City, Miyagi, Japan, 983-8520
Local Institution
Nara City, Nara, Japan, 630-8305
Local Institution
Izumi City, Osaka, Japan, 594-0071
Local Institution
Osaka City, Osaka, Japan, 5330022
Local Institution
Osaka-Shi, Osaka, Japan, 540-0006
Local Institution
Suita-City, Osaka, Japan, 5658565
Local Institution
Takatsuki City, Osaka, Japan, 5690852
Local Institution
Yao, Osaka, Japan, 5810036
Local Institution
Saga City, Saga, Japan, 840-8571
Local Institution
Saga City, Saga, Japan, 849-8501
Local Institution
Kasukabe-Shi, Saitama, Japan, 344-0035
Local Institution
Itabashi-Ku, Tokyo, Japan, 173-0015
Local Institution
Meguro-Ku, Tokyo, Japan, 153-8515
Local Institution
Shinagawa-Ku, Tokyo, Japan, 1428666
Local Institution
Toyama City, Toyama, Japan, 9308550
Local Institution
Iwakuni, Yamaguchi, Japan, 7400021
Local Institution
Fukui, Japan, 9100067
Local Institution
Kagoshima, Japan, 8920822
Local Institution
Kyoto, Japan, 6168152
Local Institution
Nagasaki, Japan, 852-8102
Local Institution
Oita, Japan, 8700033
Local Institution
Osaka, Japan, 558-8558
Local Institution
Osaka, Japan, 5510032
Local Institution
Saga, Japan, 8490917
Korea, Republic of
Local Institution
Anyang-Si, Gyeonggi-Do, Korea, Republic of, 431-070
Local Institution
Incheon, Korea, Korea, Republic of, 400-711
Local Institution
Busan, Korea, Republic of, 602-702
Local Institution
Daegu, Korea, Republic of, 705-717
Local Institution
Daegu, Korea, Republic of, 700-712
Local Institution
Daejon, Korea, Republic of, 302-718
Local Institution
Goyang, Korea, Republic of, 411-706
Local Institution
Gwang Ju, Korea, Republic of, 501-757
Local Institution
Gyeonggi, Korea, Republic of, 463-707
Local Institution
Pusan, Korea, Republic of, 602-739
Local Institution
Scongnam-Si, Korea, Republic of, 463-712
Local Institution
Seoul, Korea, Republic of, 110-744
Local Institution
Seoul, Korea, Republic of, 143-729
Local Institution
Seoul, Korea, Republic of, 130-709
Local Institution
Suwon, Korea, Republic of, 443-721
Malaysia
Local Institution
Kubang Kerian, Kelantan, Malaysia, 16150
Local Institution
Kota Samarahan, Sarawak, Malaysia, 94300
Local Institution
Batu Caves, Selangor, Malaysia, 68100
Local Institution
Kuala Lumpur, Malaysia, 56000
Local Institution
Kuala Lumpur, Malaysia, 59100
Mexico
Local Institution
Tijuana, Baja California, Mexico, 22500
Local Institution
Col. Toriello Guerra, Distrito Federal, Mexico, CP 14050
Local Institution
Mexico City, Distrito Federal, Mexico, 07760
Local Institution
Mexico City, Distrito Federal, Mexico, 14080
Local Institution
Mexico City, Distrito Federal, Mexico, 10700
Local Institution
Mexico City, Distrito Federal, Mexico, 06726
Local Institution
Mexico City, Distrito Federal, Mexico, 06070
Local Institution
Guadalajara, Jalisco, Mexico, 44600
Local Institution
Guadalajara, Jalisco, Mexico, 44656
Local Institution
Guadalajara, Jalisco, Mexico, 44200
Local Institution
Morelia, Michoacan, Mexico, 58000
Local Institution
Monterrey, Nuevo Leon, Mexico, 64000
Local Institution
Monterrey, Nuevo Leon, Mexico, 64700
Local Institution
Monterrey, Nuevo Leon, Mexico, 64710
Local Institution
Culiacan, Sinaloa, Mexico, 80020
Local Institution
Jalapa, Veracruz, Mexico, 91020
Local Institution
Puebla, Mexico, 11490
Local Institution
Queretaro, Mexico, 76000
Netherlands
Local Institution
Breda, Netherlands, 4818 CK
Local Institution
Deventer, Netherlands, 7416 SE
Local Institution
Eindhoven, Netherlands, 5623 EJ
Local Institution
Enschede, Netherlands, 7513 ER
Local Institution
Hardenberg, Netherlands, 7772 SE
Local Institution
Hilversum, Netherlands, 1213 XZ
Local Institution
Nijmegen, Netherlands, 6525 GA
Local Institution
Oss, Netherlands, 5342 BT
Local Institution
Rotterdam, Netherlands, 3045 PM
Local Institution
S-Hertogenbosch, Netherlands, 5211 NL
Local Institution
Tiel, Netherlands, 4002 WP
Local Institution
Utrecht, Netherlands, 3582 KE
Local Institution
Velp, Netherlands, 6883 AZ
Norway
Local Institution
Alesund, Norway, 6003
Local Institution
Bergen, Norway, 5021
Local Institution
Elverum, Norway, 2408
Local Institution
Flekkefjord, Norway, 4400
Local Institution
Nesttun, Norway, 5221
Local Institution
Oslo, Norway, 0407
Local Institution
Skien, Norway, 3710
Local Institution
Stavanger, Norway, 4064
Local Institution
Straume, Norway, 5353
Local Institution
Tonsberg, Norway, 3116
Local Institution
Tromso, Norway, 9038
Peru
Local Institution
Bellavista, Callao, Peru, 2176
Local Institution
Bellavista, Callao, Peru, CALLAO 2
Local Institution
Chiclayo, Lambayeque, Peru, CIX
Local Institution
Jesus Maria, Lima, Peru, LIMA 11
Local Institution
Miraflores, Lima, Peru, LIMA 18
Local Institution
San Borja, Lima, Peru, LIMA 41
Local Institution
San Martin De Porres, Lima, Peru, LIMA 31
Local Institution
Lima, Peru, LIMA 1
Local Institution
Lima, Peru, LIMA 33
Philippines
Local Institution
Laoag City, Ilocos Norte, Philippines, 2900
Local Institution
Manila, Philippines, 1000
Local Institution
Manila, Philippines, 1008
Local Institution
Naga City, Philippines, 4400
Local Institution
Pasig City, Philippines, 1600
Local Institution
Quezon, Philippines, 1100
Local Institution
Quezon City, Philippines, 1102
Local Institution
San Juan, Philippines, 1100
Poland
Local Institution
Gdynia, Poland, 81-472
Local Institution
Gdynia, Poland, 81-519
Local Institution
Gdynia, Poland, 81-423
Local Institution
Grodzisk Mazowiecki, Poland, 05-825
Local Institution
Inowroclaw, Poland, 88-100
Local Institution
Kielce, Poland, 25-763
Local Institution
Krakow, Poland, 31-135
Local Institution
Krakow, Poland, 30-092
Local Institution
Krakow, Poland, 31-202
Local Institution
Lodz, Poland, 91-347
Local Institution
Piotrkow Trybunalski, Poland, 97-300
Local Institution
Plock, Poland, 09-402
Local Institution
Plock, Poland, 09-400
Local Institution
Plonsk, Poland, 09-100
Local Institution
Poznan, Poland, 60479
Local Institution
Poznan, Poland, 60-531
Local Institution
Ruda Slaska, Poland, 41-703
Local Institution
Skierniewice, Poland, 96-100
Local Institution
Slupsk, Poland, 76-200
Local Institution
Torun, Poland, 87100
Local Institution
Warszawa, Poland, 01-138
Local Institution
Warszawa, Poland, 04-749
Local Institution
Warszawa, Poland, 04-073
Local Institution
Warszawa, Poland, 04-628
Local Institution
Wegrow, Poland, 07100
Puerto Rico
Local Institution
Cayey, Puerto Rico, 00736
Local Institution
Cidra, Puerto Rico, 00739
Local Institution
Ponce, Puerto Rico, 00717
Romania
Local Institution
Baia Mare, Romania, 430031
Local Institution
Bucharest, Romania, 050098
Local Institution
Bucharest, Romania, 030572
Local Institution
Bucharest, Romania, 020125
Local Institution
Bucharest, Romania, 021659
Local Institution
Bucharest, Romania, 011192
Local Institution
Cluj Napoca, Romania, 400347
Local Institution
Cluj Napoca, Romania, 400001
Local Institution
Iasi, Romania, 700503
Local Institution
Oradea, Romania, 410169
Local Institution
Sibiu, Romania, 550245
Local Institution
Targu-Mures, Romania, 540103
Local Institution
Timisoara, Romania, 300320
Local Institution
Timisoara, Romania, 300024
Local Institution
Tirgu Mures, Romania, 540136
Russian Federation
Local Institution
Chelyabinsk, Russian Federation, 454136
Local Institution
Chita, Russian Federation, 672090
Local Institution
Dzerzhinskiy, Russian Federation, 140091
Local Institution
Kazan, Russian Federation, 420012
Local Institution
Kemerovo, Russian Federation, 650002
Local Institution
Kirovsk, Russian Federation, 187342
Local Institution
Krasnodar, Russian Federation, 350042
Local Institution
Moscow, Russian Federation, 129090
Local Institution
Moscow, Russian Federation, 117556
Local Institution
Moscow, Russian Federation, 125424
Local Institution
Moscow, Russian Federation, 111539
Local Institution
Moscow, Russian Federation, 125367
Local Institution
Moscow, Russian Federation, 121356
Local Institution
Moscow, Russian Federation, 109240
Local Institution
Moscow, Russian Federation, 123182
Local Institution
Moscow, Russian Federation, 105229
Local Institution
Moscow, Russian Federation, 119992
Local Institution
Moscow, Russian Federation, 117593
Local Institution
Moscow, Russian Federation, 115093
Local Institution
Moscow, Russian Federation, 115487
Local Institution
Moscow, Russian Federation, 121552
Local Institution
Moscow, Russian Federation, 119048
Local Institution
Moscow, Russian Federation, 111020
Local Institution
Moscow, Russian Federation, 119121
Local Institution
Moscow, Russian Federation, 127018
Local Institution
Moscow, Russian Federation, 125284
Local Institution
Moscow, Russian Federation, 125206
Local Institution
Nizhni Novgorod, Russian Federation, 603005
Local Institution
Nizhni Novgorod, Russian Federation, 603003
Local Institution
Novosibirsk, Russian Federation, 630008
Local Institution
Novosibirsk, Russian Federation, 630054
Local Institution
Odintsovo, Russian Federation, 143000
Local Institution
Penza, Russian Federation, 440026
Local Institution
Perm, Russian Federation, 614097
Local Institution
Rostov-On-Don, Russian Federation, 344022
Local Institution
Ryazan, Russian Federation, 390026
Local Institution
Saint Petersburg, Russian Federation, 193312
Local Institution
Saint Petersburg, Russian Federation, 193144
Local Institution
Saint-Petersburg, Russian Federation, 193163
Local Institution
Saint-Petersburg, Russian Federation, 190103
Local Institution
Saint-Petersburg, Russian Federation, 196601
Local Institution
Saint-Petersburg, Russian Federation, 198013
Local Institution
Saint-Petersburg, Russian Federation, 191025
Local Institution
Samara, Russian Federation, 443070
Local Institution
Saratov, Russian Federation, 410002
Local Institution
St Petersburg, Russian Federation, 198013
Local Institution
St Petersburg, Russian Federation, 192288
Local Institution
St-Petersburg, Russian Federation, 195271
Local Institution
St-Petersburg, Russian Federation, 194354
Local Institution
St. Petersburg, Russian Federation, 197341
Local Institution
St. Petersburg, Russian Federation, 197110
Local Institution
St.-Petersburg, Russian Federation, 197341
Local Institution
St.Petersburg, Russian Federation, 199106
Local Institution
Tomsk, Russian Federation, 634012
Local Institution
Tumen, Russian Federation, 625023
Local Institution
Tver, Russian Federation, 170036
Local Institution
Voronezh, Russian Federation, 394065
Local Institution
Voronezh, Russian Federation, 394066
Local Institution
Yaroslavl, Russian Federation, 150003
Local Institution
Yaroslavl, Russian Federation, 150002
Local Institution
Yaroslavl, Russian Federation, 150030
Local Institution
Zheleznodorozhniy, Russian Federation, 143920
Local Institution
Zhukovsky, Russian Federation, 140180
Singapore
Local Institution
Singapore, Singapore, 168752
South Africa
Local Institution
Westdene, Bloemfontein, South Africa, 9301
Local Institution
Observatory, Cape Town, South Africa, 7925
Local Institution
Pretoria, Gauteng, South Africa, 0084
Local Institution
Pretoria, Gauteng, South Africa, 0132
Local Institution
Richards Bay, Kwa Zulu Natal, South Africa, 3900
Local Institution
Bellville Cape Town, Western Cape, South Africa, 7530
Local Institution
George, Western Cape, South Africa, 6529
Local Institution
Parow, Western Cape, South Africa, 7505
Local Institution
Somerset West, Western Cape, South Africa, 7130
Local Institution
Worcester, Western Cape, South Africa, 6850
Spain
Local Institution
San Juan, Alicante, Spain, 03550
Local Institution
Torrevieja, Alicante, Spain, 03186
Local Institution
La Canada, Almeria, Spain, 04120
Local Institution
Lugo, Galicia, Spain, 27003
Local Institution
Albacete, Spain, 02006
Local Institution
Barcelona, Spain, 08003
Local Institution
Barcelona, Spain, 08035
Local Institution
Elda, Spain, 03600
Local Institution
Figueres, Spain, 17600
Local Institution
Gerona, Spain, 17007
Local Institution
Las Palmas, Spain, 35010
Local Institution
Madrid, Spain, 28046
Local Institution
Madrid, Spain, 28040
Local Institution
Madrid, Spain, 28006
Local Institution
Palma De Mallorca, Spain, 07010
Local Institution
San Sebastian De Los Reyes, Spain, 28703
Local Institution
Tarragona, Spain, 43007
Local Institution
Viladecans, Spain, 08840
Sweden
Local Institution
Goteberg, Sweden, 413 45
Local Institution
Helsingborg, Sweden, 251 87
Local Institution
Linkoping, Sweden, 581 85
Local Institution
Lund, Sweden, 222 21
Local Institution
Orebro, Sweden, 701 85
Local Institution
Skelleftea, Sweden, 931 86
Local Institution
Stockholm, Sweden, 111 35
Local Institution
Stockholm, Sweden, 141 86
Local Institution
Stockholm, Sweden, 118 83
Local Institution
Stockholm, Sweden, 111 57
Local Institution
Uppsala, Sweden, 751 85
Local Institution
Vaxjo, Sweden, 351 85
Switzerland
Local Institution
Baden, Switzerland, 5404
Local Institution
Bern, Switzerland, 3010
Taiwan
Local Institution
Taipei, Taiwan, 112
Local Institution
Taipei, Taiwan, 104
Local Institution
Taipei, Taiwan, 111
Local Institution
Taipei, Taiwan, 100
Local Institution
Taipei, Taiwan, 220
Turkey
Local Institution
Ankara, Turkey, 06100
Local Institution
Eskisehir, Turkey, 26480
Local Institution
Izmir, Turkey, 35100
Ukraine
Local Institution
Chernivtsy, Ukraine, 58013
Local Institution
Dnipropetrovsk, Ukraine, 49060
Local Institution
Dnipropetrovsk, Ukraine, 49006
Local Institution
Donetsk, Ukraine, 83003
Local Institution
Donetsk, Ukraine, 83045
Local Institution
Donetsk, Ukraine, 83114
Local Institution
Ivano-Frankivsk, Ukraine, 76025
Local Institution
Kharkiv, Ukraine, 61018
Local Institution
Kharkiv, Ukraine, 61115
Local Institution
Kharkov, Ukraine, 61039
Local Institution
Kharkov, Ukraine, 61178
Local Institution
Kharkov, Ukraine, 61002
Local Institution
Kiev, Ukraine, 01032
Local Institution
Kyiv, Ukraine, 03680
Local Institution
Kyiv, Ukraine, 01103
Local Institution
Kyiv, Ukraine, 04050
Local Institution
Kyiv, Ukraine, 04107
Local Institution
Kyiv, Ukraine, 02660
Local Institution
Kyiv, Ukraine, 03115
Local Institution
Kyiv, Ukraine, 03049
Local Institution
Kyiv, Ukraine, 01023
Local Institution
Kyiv, Ukraine, 02091
Local Institution
Lugansk, Ukraine, 91011
Local Institution
Lugansk, Ukraine, 91016
Local Institution
Lutsk, Ukraine, 43024
Local Institution
Lviv, Ukraine, 79015
Local Institution
Lviv, Ukraine, 79013
Local Institution
Mykolayiv, Ukraine, 54003
Local Institution
Odessa, Ukraine, 65039
Local Institution
Odessa, Ukraine, 65114
Local Institution
Odessa, Ukraine, 65025
Local Institution
Odessa, Ukraine, 65009
Local Institution
Uzhgorod, Ukraine, 88000
Local Institution
Vinnitsa, Ukraine, 21029
Local Institution
Zaporozhye, Ukraine, 69035
Local Institution
Zhytomyr, Ukraine, 10002
United Kingdom
Local Institution
Aberdeen, Aberdeenshire, United Kingdom, AB25 2ZN
Local Institution
Glasgow, Aberdeenshire, United Kingdom, G11 6NT
Local Institution
Belfast, Antrim, United Kingdom, BT14 6AB
Local Institution
Craigavon, Armagh, United Kingdom, BT63 5QQ
Local Institution
Cambridge, Cambridgeshire, United Kingdom, CB2 2QQ
Local Institution
Peterborough, Cambridgeshire, United Kingdom, PE2 5GP
Local Institution
Chesterfield, Derbyshire, United Kingdom, S44 5BL
Local Institution
Chesterfield, Derbyshire, United Kingdom, S40 4TF
Local Institution
Bournemouth, Dorset, United Kingdom, BH7 7DW
Local Institution
Glasgow, Dumbartonshire, United Kingdom, G11 6NT
Local Institution
Chichester, East Sussex, United Kingdom, PO19 6SE
Local Institution
Colchester, Essex, United Kingdom, C03 4LN
Local Institution
Romford, Essex, United Kingdom, RH7 0AG
Local Institution
Denmark Hill, Greater London, United Kingdom, SE5 9RS
Local Institution
London, Greater London, United Kingdom, SW17 0RE
Local Institution
Newport, Gwent, United Kingdom, NP20 2UB
Local Institution
Barnet, Hertfordshire, United Kingdom, EN5 3DJ
Local Institution
Cardiff, Mid Glamorgan, United Kingdom, CF14 4XW
Local Institution
Llandough, Mid Glamorgan, United Kingdom, CF64 2XX
Local Institution
Harrow, Middlesex, United Kingdom, HA1 3UJ
Local Institution
Nottingham, Nottinghamshire, United Kingdom, NG5 1PB
Local Institution
Worksop, Nottinghamshire, United Kingdom, S81 OBD
Local Institution
Paisley, Renfrewshire, United Kingdom, PA2 9PN
Local Institution
Barnsley, South Yorkshire, United Kingdom, S75 2EP
Local Institution
Doncaster, South Yorkshire, United Kingdom, DN2 5LT
Local Institution
Stirling, Stirlingshire, United Kingdom, FK8 2AU
Local Institution
Glasgow, Strathclyde, United Kingdom, G51 4TF
Local Institution
Bury St Edmunds, Suffolk, United Kingdom, IP31 2HD
Local Institution
Bury St Edmunds, Suffolk, United Kingdom, IP33 2QZ
Local Institution
Bury St. Edmunds, Suffolk, United Kingdom, IP30 9QU
Local Institution
Ipswich, Suffolk, United Kingdom, IP14 2PU
Local Institution
Ipswich, Suffolk, United Kingdom, IP7 5DN
Local Institution
Newcastle Upon Tyne, Tyne And Wear, United Kingdom, NE1 4LP
Local Institution
Swansea, West Glamorgan, United Kingdom, SA6 6NL
Local Institution
Livingston, West Lothian, United Kingdom, EH54 6PP
Local Institution
Birmingham, West Midlands, United Kingdom, B18 7QH
Local Institution
Westbury, Wiltshire, United Kingdom, BA13 3JD
Local Institution
York, Yorkshire, United Kingdom, YO31 8HE
Local Institution
Antrim, United Kingdom, BT41 2RL
Local Institution
Blackpool, United Kingdom, FY3 8NR
Local Institution
Glasgow, United Kingdom, G21 3UW

Sponsors and Collaborators

Bristol-Myers Squibb

Investigators

Study Director:

Bristol-Myers Squibb

More Information

Additional Information:

BMS Clinical Trials Disclosure This link exits the ClinicalTrials.gov site

Investigator Inquiry form This link exits the ClinicalTrials.gov site

For FDA Safety Alerts and Recalls refer to the following link: http://www.fda.gov/MEDWATCH/safety.htm This link exits the ClinicalTrials.gov site

No publications provided by Bristol-Myers Squibb

Additional publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):

Lopes RD, Al-Khatib SM, Wallentin L, Yang H, Ansell J, Bahit MC, De Caterina R, Dorian P, Easton JD, Erol C, Ezekowitz JA, Gersh BJ, Granger CB, Hohnloser SH, Horowitz J, Hylek EM, McMurray JJ, Mohan P, Vinereanu D, Alexander JH. Efficacy and safety of apixaban compared with warfarin according to patient risk of stroke and of bleeding in atrial fibrillation: a secondary analysis of a randomised controlled trial. Lancet. 2012 Nov 17;380(9855):1749-58. doi: 10.1016/S0140-6736(12)60986-6. Epub 2012 Oct 2.

Granger CB, Alexander JH, McMurray JJ, Lopes RD, Hylek EM, Hanna M, Al-Khalidi HR, Ansell J, Atar D, Avezum A, Bahit MC, Diaz R, Easton JD, Ezekowitz JA, Flaker G, Garcia D, Geraldes M, Gersh BJ, Golitsyn S, Goto S, Hermosillo AG, Hohnloser SH, Horowitz J, Mohan P, Jansky P, Lewis BS, Lopez-Sendon JL, Pais P, Parkhomenko A, Verheugt FW, Zhu J, Wallentin L; ARISTOTLE Committees and Investigators. Apixaban versus warfarin in patients with atrial fibrillation. N Engl J Med. 2011 Sep 15;365(11):981-92. Epub 2011 Aug 27.

Responsible Party:	Bristol-Myers Squibb
ClinicalTrials.gov Identifier:	NCT00412984 History of Changes
Other Study ID Numbers:	CV185-030
Study First Received:	December 18, 2006
Results First Received:	January 25, 2013
Last Updated:	April 29, 2013
Health Authority:	United States: Food and Drug Administration

Additional relevant MeSH terms:

Atrial Fibrillation
Atrial Flutter
Arrhythmias, Cardiac
Heart Diseases
Cardiovascular Diseases
Pathologic Processes

Warfarin
Anticoagulants
Hematologic Agents
Therapeutic Uses
Pharmacologic Actions

ClinicalTrials.gov processed this record on May 23, 2013

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