Data and Sample Collection Study to Elucidate the Mechanisms of Eosinophilic Disorders

This study is currently recruiting participants. (see Contacts and Locations)
Verified April 2013 by Children's Hospital Medical Center, Cincinnati
Sponsor:
Information provided by (Responsible Party):
Children's Hospital Medical Center, Cincinnati
ClinicalTrials.gov Identifier:
NCT00267501
First received: December 15, 2005
Last updated: January 7, 2014
Last verified: April 2013
  Purpose

The purpose of this study is to elucidate the mechanisms underlying eosinophil growth, survival, migration, and function and to investigate and further characterize the pathophysiology of, clinical manifestations of, and spectrum of disease severity of eosinophilic inflammation in humans.


Condition
Eosinophilic Gastrointestinal Disease Eosinophilic Inflammatory Disease
Food Allergy

Study Type: Observational
Study Design: Time Perspective: Prospective
Official Title: Eosinophils and Inflammation, an Expanded Study

Resource links provided by NLM:


Further study details as provided by Children's Hospital Medical Center, Cincinnati:

Estimated Enrollment: 5000
Study Start Date: May 2005
Estimated Study Completion Date: January 2050
Estimated Primary Completion Date: January 2050 (Final data collection date for primary outcome measure)
  Eligibility

Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population

Patients with eosinophilic disorders and patients without eosinophilic disorders to serve as normal controls

Criteria

Inclusion Criteria:

  • Signed informed consent obtained from the patient or parent/guardian. Assent will be obtained from all minors 11 years of age and older.
  • Carrying a diagnosis of eosinophilic gastrointestinal disease, eosinophilic inflammatory disease, or food allergy OR family member, or normal control
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00267501

Contacts
Contact: Tommie Grotjan, BS 513-803-1655 tommie.grotjan@cchmc.org

Locations
United States, Ohio
Cincinnati Children's Hospital Medical Center Recruiting
Cincinnati, Ohio, United States, 45229-3039
Principal Investigator: Marc E. Rothenberg, M.D., Ph.D.         
Sponsors and Collaborators
Children's Hospital Medical Center, Cincinnati
Investigators
Principal Investigator: Marc E. Rothenberg, M.D., Ph.D. Children's Hospital Medical Center, Cincinnati
  More Information

No publications provided

Responsible Party: Children's Hospital Medical Center, Cincinnati
ClinicalTrials.gov Identifier: NCT00267501     History of Changes
Other Study ID Numbers: 04-12-8, R01 DK075401
Study First Received: December 15, 2005
Last Updated: January 7, 2014
Health Authority: United States: Institutional Review Board

Keywords provided by Children's Hospital Medical Center, Cincinnati:
Eosinophilic Disorders

Additional relevant MeSH terms:
Food Hypersensitivity
Gastrointestinal Diseases
Digestive System Diseases
Eosinophilia
Hypersensitivity, Immediate
Hypersensitivity
Immune System Diseases
Leukocyte Disorders
Hematologic Diseases

ClinicalTrials.gov processed this record on July 29, 2014