Nitroglycerin Versus Terbutaline for Intrapartum Fetal Resuscitation

This study has been completed.

First Received: September 12, 2005 Last Updated: June 17, 2009 History of Changes

Sponsor:	Stanford University
Information provided by:	Stanford University
ClinicalTrials.gov Identifier:	NCT00185887

Purpose

To compare nitroglycerin and terbutaline for intrapartum fetal heart rate resuscitation

Condition	Intervention
Fetal Distress	Drug: nitroglycerin and terbutaline

Study Type:	Interventional
Study Design:	Treatment, Randomized, Double-Blind, Active Control, Single Group Assignment
Official Title:	Nitroglycerin Versus Terbutaline for Intrapartum Fetal Resuscitation

Resource links provided by NLM:

Drug Information available for: Nitroglycerin Terbutaline Terbutaline sulfate

U.S. FDA Resources

Further study details as provided by Stanford University:

Primary Outcome Measures:

resolution of abnormal fetal heart tracing

Secondary Outcome Measures:

cesarean section rate
operative vaginal delivery rate
neonatal outcomes

Enrollment:	110
Study Start Date:	October 2003
Study Completion Date:	October 2007
Primary Completion Date:	July 2006 (Final data collection date for primary outcome measure)

Eligibility

Ages Eligible for Study:	18 Years and older
Genders Eligible for Study:	Female
Accepts Healthy Volunteers:	No

Criteria

Inclusion Criteria::

nonreassuring fetal heart rate tracing

Exclusion Criteria:- maternal cardiac disease, placental abruption, intrauterine growth restriction, prior cesarean section

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00185887

Locations

United States, California
Stanford University School of Medicine
Stanford, California, United States, 94305

Sponsors and Collaborators

Stanford University

Investigators

Principal Investigator:

Yasser Yehia El-Sayed

Stanford University

More Information

Additional Information:

American Journal of Obstetrics and Gynecology. 2007 Oct;197(4):414.el-6 This link exits the ClinicalTrials.gov site

No publications provided

Responsible Party:	Stanford University School of Medicine ( Yasser Yehia El-Sayed, Principal Investigator )
Study ID Numbers:	79504
Study First Received:	September 12, 2005
Last Updated:	June 17, 2009
ClinicalTrials.gov Identifier:	NCT00185887 History of Changes
Health Authority:	United States: Institutional Review Board

Additional relevant MeSH terms:

Respiratory System Agents
Neurotransmitter Agents
Vasodilator Agents
Molecular Mechanisms of Pharmacological Action
Adrenergic Agents
Adrenergic beta-Agonists
Sympathomimetics
Physiological Effects of Drugs
Anti-Asthmatic Agents
Reproductive Control Agents
Cardiovascular Agents

Adrenergic Agonists
Pharmacologic Actions
Terbutaline
Nitroglycerin
Signs and Symptoms
Fetal Distress
Tocolytic Agents
Autonomic Agents
Therapeutic Uses
Peripheral Nervous System Agents
Bronchodilator Agents

ClinicalTrials.gov processed this record on November 25, 2009