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| Sponsor: | Telik |
|---|---|
| Information provided by: | Telik |
| ClinicalTrials.gov Identifier: | NCT00057720 |
Purpose
The purpose of this study is to demonstrate superiority in survival in favor of TLK286 as compared to active control therapy with Doxil/Caelyx or Hycamtin in the intent-to-treat (ITT) populations.
| Condition | Intervention | Phase |
|---|---|---|
|
Ovarian Neoplasms |
Drug: TLK286 HCl for injection Drug: topotecan hydrochloride for injection Drug: doxorubicin HCl liposome injection |
Phase III |
| Study Type: | Interventional |
| Study Design: | Treatment, Randomized, Open Label, Active Control, Safety/Efficacy Study |
| Official Title: | Phase 3 Randomized Study of TLK286 (Telcyta) Versus Doxil/Caelyx or Hycamtin as Third-Line Therapy in Platinum Refractory or Resistant Ovarian Cancer [ASSIST-1 (Assessment of Survival In Solid Tumors-1)] |
Eligibility| Ages Eligible for Study: | 18 Years and older |
| Genders Eligible for Study: | Female |
| Accepts Healthy Volunteers: | No |
Inclusion criteria include:
Exclusion criteria include:
Contacts and Locations
Hide Study Locations| United States, Arkansas | |
| Little Rock Hematology Oncology Associates | |
| Little Rock, Arkansas, United States, 72205 | |
| University of Arkansas for Medical Sciences | |
| Little Rock, Arkansas, United States, 72205 | |
| United States, California | |
| Southwest Cancer Care | |
| Poway, California, United States, 92064 | |
| David Geffen School of Medicine at UCLA | |
| Los Angeles, California, United States, 90095 | |
| Loma Linda University Medical Center | |
| Loma Linda, California, United States, 92354 | |
| Gyncologic Oncology Associates | |
| Newport Beach, California, United States, 92663 | |
| Southwest Cancer Care | |
| Escondido, California, United States, 92025 | |
| Southwest Cancer Care | |
| Murrieta, California, United States, 92562 | |
| Sharp Healthcare Clinical Oncology Research | |
| San Diego, California, United States, 92123 | |
| Bay Area Research Cancer Group | |
| Concord, California, United States, 94520 | |
| Gynecologic Oncology Associates | |
| La Jolla, California, United States, 92037 | |
| Kaiser Permanente Oncology Clinical Trials Program | |
| Vallejo, California, United States, 94589 | |
| Kaiser Permanente Oncology Clinical Trials Program | |
| Oakland, California, United States, 94611 | |
| Kaiser Permanente Oncology Clinical Trials Program | |
| Sacramento, California, United States, 95825 | |
| Kaiser Permanente Oncology Clinical Trials Program | |
| San Francisco, California, United States, 94115 | |
| Kaiser Permanente Oncology Clinical Trials Program | |
| Santa Clara, California, United States, 95051 | |
| Kaiser Permanente Oncology Clinical Trails Program | |
| Santa Teresa, California, United States, 95119 | |
| Kaiser Permanente Oncology Clinial Trials Program | |
| Walnut Creek, California, United States, 94596 | |
| Kaiser Permanente Oncology Clinical Trials Program | |
| Hayward, California, United States, 94545 | |
| Kaiser Permanente Oncology Clinical Trials Program | |
| Roseville, California, United States, 95661 | |
| Providence Saint Joseph Medical Center | |
| Burbank, California, United States, 91505-4866 | |
| Kaiser Permanente Oncology Clinical Trials Program | |
| Santa Rosa, California, United States, 95403 | |
| Kaiser Permanente Oncology Clinical Trials Program | |
| South San Francisco, California, United States, 94080 | |
| Kaiser Permanente Oncology Clinical Trials Program | |
| Redwood City, California, United States, 94063 | |
| Sharp Memorial Hospital | |
| San Diego, California, United States, 92123 | |
| Grossmont Hospital | |
| La Mesa, California, United States, 91942 | |
| Sharp Rees-Stealy | |
| San Diego, California, United States, 92123 | |
| Sharp Rees-Stealy | |
| La Mesa, California, United States, 91942 | |
| Medical Oncology Associates-SD | |
| San Diego, California, United States, 92123 | |
| Rosalba Rodriguez, M. D. | |
| Chula Vista, California, United States, 91911 | |
| Marilyn Norton, M. D. | |
| Chula Vista, California, United States, 91911 | |
| N. County Oncology Medical | |
| Oceanside, California, United States, 92056 | |
| LLU Faculty Medical Offices | |
| Loma Linda, California, United States, 92354 | |
| Southern California Permanente Medical Group | |
| San Diego, California, United States, 92120 | |
| Southern California Permanente Medical Group | |
| Baldwin Park, California, United States, 91706 | |
| California Oncology of the Central Valley | |
| Fresno, California, United States, 93710 | |
| Loma Linda University Medical Center | |
| Loma Linda, California, United States, 92354 | |
| LLU Faculty Meidical Offices | |
| Loma Linda, California, United States, 92354 | |
| Women's Cancer Center - Community Hospital Los Gatos | |
| Los Gatos, California, United States, 95032 | |
| Kaiser Permanente Oncology Clinical Trials Program | |
| San Rafael, California, United States, 94903 | |
| United States, Connecticut | |
| Whittingham Cancer Center at Norwalk Hospital | |
| Norwalk, Connecticut, United States, 06856 | |
| Hematology Oncology, P.C. | |
| Stamford, Connecticut, United States, 06902 | |
| United States, Florida | |
| Gynecologic Oncology | |
| Orlando, Florida, United States, 32804 | |
| Women's Cancer Research Foundation, Inc. | |
| S. Miami, Florida, United States, 33143 | |
| Sheridan Clinical Research, Inc. | |
| Hollywood, Florida, United States, 33021 | |
| University of Florida Health Science Center/Jacksonville | |
| Jacksonville, Florida, United States, 32209 | |
| Palm Beach Cancer Institute | |
| Palm Beach Gardens, Florida, United States, 33410 | |
| Memorial Regional Hospital | |
| Hollywood, Florida, United States, 33021 | |
| Gynecologic Oncology Associates | |
| Pembroke Pines, Florida, United States, 33028 | |
| Palm Beach Cancer Institute | |
| West Palm Beach, Florida, United States, 33401 | |
| Florida Hospital | |
| Orlando, Florida, United States, 32803 | |
| Palm Beach Cancer Institute | |
| Wellington, Florida, United States, 33414 | |
| Sheridan Clinical Research, Inc. | |
| Hollywood, Florida, United States, 33021 | |
| Memorial Regional Hospital | |
| Hollywood, Florida, United States, 33021 | |
| Gynecologic Oncology Associates | |
| Pembroke Pines, Florida, United States, 33028 | |
| The Center for Hematology-Oncology | |
| Boca Raton, Florida, United States, 33486 | |
| The Center for Hematology-Oncology | |
| Delray Beach, Florida, United States, 33484 | |
| Hematology/Oncology Associates of Treasure Coast | |
| Port St. Lucie, Florida, United States, 34952 | |
| Florida Hospital Memorial Division, Cancer Care Center | |
| Ormond Beach, Florida, United States, 32174 | |
| Florida Hospital Memorial Division | |
| Ormond Beach, Florida, United States, 32174 | |
| United States, Georgia | |
| Suburban Hematology-Oncology Associates | |
| Lawrenceville, Georgia, United States, 30045 | |
| Memorial Health University Medical Center | |
| Savannah, Georgia, United States, 31404 | |
| Suburban Hematology Oncology | |
| Snellville, Georgia, United States, 30078 | |
| Suburban Hematology Oncology | |
| Duluth, Georgia, United States, 30096 | |
| United States, Hawaii | |
| Univ. of Hawaii, Kapiolani Medical Center for Women and Children | |
| Honolulu, Hawaii, United States, 96826 | |
| Straub Clinic and Hospital | |
| Honolulu, Hawaii, United States, 96826 | |
| Kaiser Permanente - Moanalua Medical Center | |
| Honolulu, Hawaii, United States, 96819 | |
| United States, Illinois | |
| MacNeal Cancer Center | |
| Berwyn, Illinois, United States, 60402 | |
| Cancer Care Specialists of Central IL | |
| Decatur, Illinois, United States, 62526 | |
| Cancer Care Specialists of Central IL-Crossroads Cancer Care Center | |
| Effingham, Illinois, United States, 62401 | |
| Decatur Memorial Hospital | |
| Decatur, Illinois, United States, 62526 | |
| North Shore Oncology Hematology Associates | |
| McHenry, Illinois, United States, 60050 | |
| Joliet Oncology-Hematology Associates, Ltd. | |
| Morris, Illinois, United States, 60450 | |
| Joliet Oncology-Hematology Associates, Ltd. | |
| Flossmoor, Illinois, United States, 60422 | |
| Hematology Oncology Associates of Illinois (HOAI) | |
| Chicago, Illinois, United States, 60657 | |
| Hematology Oncology Associates of Illinois (HOAI) | |
| Skokie, Illinois, United States, 60076 | |
| Swedish Covenant Cancer Center | |
| Chicago, Illinois, United States, 60625 | |
| North Shore Oncology Hematology Associates - Deerpath Medical Associates | |
| Lake Forest, Illinois, United States, 60045 | |
| North Shore Oncology Hematology Associates | |
| Barrington, Illinois, United States, 60010 | |
| North Shore Oncology Hematology Associates | |
| Libertyville, Illinois, United States, 60048 | |
| Joliet Oncology-Hematology Associates, Ltd. | |
| Joliet, Illinois, United States, 60435 | |
| Midwest Cancer Research Group, Inc. | |
| Skokie, Illinois, United States, 60077 | |
| United States, Indiana | |
| Indiana University Medical Center | |
| Indianapolis, Indiana, United States, 46202 | |
| St. Joseph's Regional | |
| South Bend, Indiana, United States, 46617 | |
| St. Vincent Gynecologic Oncology | |
| Indianapolis, Indiana, United States, 46260 | |
| Michiana Hematology Oncology | |
| Elkhart, Indiana, United States, 46514 | |
| St. Vincent Hospital and Health Care Center | |
| Indianapolis, Indiana, United States, 46260 | |
| St. Vincent Hospital and Helath Care Center | |
| Indianapolis, Indiana, United States, 46260 | |
| Saint Joseph's Regional | |
| South Bend, Indiana, United States, 46634 | |
| Elkhart General Hospital | |
| Elkhart, Indiana, United States, 46514 | |
| Michiana Hematology Oncology | |
| South Bend, Indiana, United States, 46617 | |
| Indiana Cancer Pavilion | |
| Indianapolis, Indiana, United States, 46202 | |
| United States, Iowa | |
| University of Iowa | |
| Iowa City, Iowa, United States, 52242 | |
| University of Iowa Hospitals and Clinics | |
| Iowa City, Iowa, United States, 52242 | |
| United States, Kansas | |
| Associates in Women's Health | |
| Wichita, Kansas, United States, 67214 | |
| Research Support Personnel, LLC | |
| Wichita, Kansas, United States, 67208 | |
| United States, Kentucky | |
| Oncology/Hematology Care, Inc. | |
| Crestview, Kentucky, United States, 41017 | |
| Univ. of Louisville, Div. of Gynecologic Oncology | |
| Louisville, Kentucky, United States, 40202 | |
| United States, Louisiana | |
| LSU Health Sciences Center | |
| Shreveport, Louisiana, United States, 71103 | |
| Ochsner Clinic Foundation | |
| New Orleans, Louisiana, United States, 70121 | |
| Hematology and Oncology Specialists, LLC | |
| New Orleans, Louisiana, United States, 70115 | |
| Hematology and Oncology Specialists, LLC | |
| Covington, Louisiana, United States, 70433 | |
| OncRx (Pharmacy) | |
| Metairie, Louisiana, United States, 70002 | |
| United States, Maryland | |
| Center for Cancer and Blood Disorders | |
| Bethesda, Maryland, United States, 20817 | |
| Sinai Cancer Institute | |
| Baltimore, Maryland, United States, 21205 | |
| United States, Massachusetts | |
| St. Elizabeth's Med. Ctr. | |
| Boston, Massachusetts, United States, 02135 | |
| United States, Michigan | |
| Sparrow Regional Cancer Center | |
| Lansing, Michigan, United States, 48909 | |
| St. Joseph Mercy Hospital | |
| Ann Arbor, Michigan, United States, 48106 | |
| United States, Minnesota | |
| St. Mary's Duluth Clinic | |
| Duluth, Minnesota, United States, 55805 | |
| United States, Missouri | |
| Gynecology & Oncology Consultants, PC | |
| St. Louis, Missouri, United States, 63141 | |
| Ellis Fischel Cancer Center | |
| Columbia, Missouri, United States, 65203 | |
| St. Louis University, Dept. of Ob-Gyn and Women's Health | |
| St. Louis, Missouri, United States, 63117 | |
| Saint John's Mercy Hospital | |
| St. Louis, Missouri, United States, 63141 | |
| United States, Montana | |
| Hematology & Oncology Centers Northern Rockies | |
| Billings, Montana, United States, 59101 | |
| Deaconess Billings Clinic | |
| Billings, Montana, United States, 59101 | |
| Hematology Oncology Centers of the Northern Rockies | |
| Butte, Montana, United States, 59701 | |
| United States, Nebraska | |
| Horizon's West Medical Group | |
| Scottsbluff, Nebraska, United States, 69361 | |
| United States, Nevada | |
| Nevada Cancer Center | |
| Las Vegas, Nevada, United States, 89109 | |
| United States, New Jersey | |
| The Cancer Institute of New Jersey | |
| New Brunswick, New Jersey, United States, 08901 | |
| Jersey Shore University Medical Center | |
| Neptune, New Jersey, United States, 07754 | |
| Robert Wood Johnson University Hospital | |
| New Brunswick, New Jersey, United States, 08903 | |
| United States, New Mexico | |
| UNM Cancer Research and Treatment Center | |
| Albuquerque, New Mexico, United States, 87131 | |
| United States, New York | |
| The Mary Imogene Bassett Hospital | |
| Cooperstown, New York, United States, 13326 | |
| NYU School of Medicine | |
| New York, New York, United States, 10016 | |
| The Union State Bank Cancer Center at Nyack Hospital | |
| Nyack, New York, United States, 10960 | |
| Med-Onc/Hem | |
| Malone, New York, United States, 12953 | |
| Gynecologic-Oncology | |
| Rochester, New York, United States, 14620 | |
| Hematology-Oncology Associates of Rockland | |
| New City, New York, United States, 10956 | |
| Good Samaritan Hospital Medical Center | |
| West Islip, New York, United States, 11795 | |
| Benjamin Schwartz, M.D. | |
| Babylon, New York, United States, 11702 | |
| South Bay OB/GYN | |
| West Islip, New York, United States, 11795 | |
| Memorial Sloan Kettering Cancer Center | |
| New York, New York, United States, 11021 | |
| Comprehensive Cancer Center Medical Practice Offices | |
| New York, New York, United States, 10016 | |
| Bellevue Hospital Center | |
| New York, New York, United States, 10016 | |
| North Shore-Long Island Jewish Health System/Medical Center | |
| New Hyde Park, New York, United States, 11040 | |
| New York University Medical Center - Tisch Hospital | |
| New York, New York, United States, 10016 | |
| Long Island Jewish Medical Center | |
| New Hyde Park, New York, United States, 11040 | |
| United States, North Carolina | |
| Presbyterian Hospital Center for Cancer Research | |
| Charlotte, North Carolina, United States, 28204 | |
| Wake Forest University School of Medicine | |
| Winston-Salem, North Carolina, United States, 27157 | |
| Blumenthal Cancer Center | |
| Charlotte, North Carolina, United States, 28203 | |
| Salem Research Group, Inc. | |
| Winston-Salem, North Carolina, United States, 27103 | |
| Piedmont Hematology Oncology Assoc., PA-Salem Research Group | |
| Winston-Salem, North Carolina, United States, 27103 | |
| Presbyterian Gynecologic Oncology | |
| Charlotte, North Carolina, United States, 28204 | |
| United States, North Dakota | |
| Dakota Cancer Institute | |
| Fargo, North Dakota, United States, 58103 | |
| Mid Dakota Clinic | |
| Bismarck, North Dakota, United States, 58501 | |
| Odyssey Research Services | |
| Bismarck, North Dakota, United States, 58501 | |
| Odyssey Research Services | |
| Fargo, North Dakota, United States, 58104 | |
| United States, Ohio | |
| Gynecologic Oncology | |
| Columbus, Ohio, United States, 43222 | |
| Mid-Ohio Oncology Hematology | |
| Columbus, Ohio, United States, 43213 | |
| Mid-Ohio Oncology Hematology St. Anne's | |
| Columbus, Ohio, United States, 43081 | |
| Oncology/Hematology Care, Inc. | |
| Cincinnati, Ohio, United States, 45242 | |
| Oncology/Hematology Care, Inc. | |
| Cincinnati, Ohio, United States, 45236 | |
| Mount Carmel Health | |
| Columbus, Ohio, United States, 43222 | |
| Oncology/Hematology Care, Inc. | |
| Cincinnati, Ohio, United States, 45230 | |
| Oncology/Hematology Care, Inc. | |
| Cincinnati, Ohio, United States, 45219 | |
| Wright State Univ. School of Medicine | |
| Dayton, Ohio, United States, 45409 | |
| MetroHealth Medical Center | |
| Cleveland, Ohio, United States, 44109 | |
| University Hospital | |
| Cincinnati, Ohio, United States, 45219 | |
| Hillcrest Hospital Cancer Center | |
| Mayfield Heights, Ohio, United States, 44124 | |
| Barrett Cancer Center | |
| Cincinnati, Ohio, United States, 45219 | |
| UC Physician's Medical Arts Bldg. | |
| Cincinnati, Ohio, United States, 45219 | |
| Oncology/Hematology Care, Inc. | |
| Cincinnati, Ohio, United States, 45013 | |
| Mid Ohio Oncology Hematology | |
| Columbus, Ohio, United States, 43213 | |
| Metro Health Medical Center | |
| Cleveland, Ohio, United States, 44109 | |
| Barrett Cancer Center | |
| Cincinnati, Ohio, United States, 45219-0501 | |
| UC Physician's Medical Arts Building | |
| Cincinnati, Ohio, United States, 45219 | |
| United States, Oklahoma | |
| University of Oklahoma Health Sciences Center | |
| Oklahoma City, Oklahoma, United States, 73104 | |
| OU Medical Center - Everett Tower | |
| Oklahoma City, Oklahoma, United States, 73104 | |
| Presbyterian | |
| Oklahoma City, Oklahoma, United States, 73104 | |
| OU Physicians' Bldg. | |
| Oklahoma City, Oklahoma, United States, 73104 | |
| United States, Oregon | |
| Oregon Health Science University | |
| Portland, Oregon, United States, 97239 | |
| Kaiser Permanente Nw, Oncology Research | |
| Portland, Oregon, United States, 97227 | |
| Oregon Health & Science University | |
| Portland, Oregon, United States, 97239-3098 | |
| United States, Pennsylvania | |
| Hematology & Oncology Associates of NEPA | |
| Dunmore, Pennsylvania, United States, 18512 | |
| Magee-Womens Hospital | |
| Pittsburgh, Pennsylvania, United States, 15213 | |
| Abington Mem. Hospita/Rosenfield Cancer Center | |
| Abington, Pennsylvania, United States, 19001 | |
| Mercy Health Partners | |
| Scranton, Pennsylvania, United States, 18510 | |
| Moses Taylor Hospital | |
| Scranton, Pennsylvania, United States, 18510 | |
| Community Medical Center | |
| Scranton, Pennsylvania, United States, 18510 | |
| Viewmont Medical Services | |
| Scranton, Pennsylvania, United States, 18508 | |
| Advanced Imaging | |
| Dunmore, Pennsylvania, United States, 18512 | |
| Associates in Hematology-Oncology, P.C. | |
| Upland, Pennsylvania, United States, 19013 | |
| United States, South Carolina | |
| Gynecologic Oncology Research and Development | |
| Greenville, South Carolina, United States, 29605 | |
| Carolina Center of Gynecologic Oncology, PA | |
| Charleston, South Carolina, United States, 29407 | |
| Gynecologic Oncology Research and Development | |
| Spartanburg, South Carolina, United States, 29303 | |
| South Carolina Oncology Associates, PA | |
| Columbia, South Carolina, United States, 29201 | |
| United States, South Dakota | |
| Sioux Calley Clinic OBGYN Ltd. | |
| Sioux Falls, South Dakota, United States, 57105 | |
| Sioux Valley Hospital - North Center Radiology | |
| Sioux Falls, South Dakota, United States, 57104 | |
| Sioux Valley Clinic Oncology | |
| Sioux Falls, South Dakota, United States, 57104 | |
| Sioux Valley Clinic Clinical Research Center | |
| Sioux Falls, South Dakota, United States, 57104 | |
| United States, Tennessee | |
| The Consultant Group | |
| Nashville, Tennessee, United States, 37205 | |
| Fort Sanders Parkwest Medical Center | |
| Knoxville, Tennessee, United States, 37923 | |
| The Sarah Cannon Cancer Center/Tennessee Oncology, PLLC | |
| Nashville, Tennessee, United States, 37203 | |
| Chattanooga Oncology & Hematology Associates, P.C. | |
| Chattanooga, Tennessee, United States, 37404 | |
| The Sarah Cannon Cancer Center/Tennessee Oncology, PLLC | |
| Hermitage, Tennessee, United States, 37076 | |
| The Sarah Cannon Cancer Center/Tennessee Oncology, PLLC | |
| Nashville, Tennessee, United States, 37207 | |
| The Sarah Cannon Cancer Center/Tennessee Oncology, PLLC | |
| Murfreesboro, Tennessee, United States, 37130 | |
| The Sarah Cannon Cancer Center/Tennessee Oncology, PLLC | |
| Nashville, Tennessee, United States, 37205 | |
| The Sarah Cannon Cancer Center/Tennessee Oncology, PLLC | |
| Gallatin, Tennessee, United States, 37066 | |
| The Sarah Cannon Cancer Center/Tennessee Oncology, PLLC | |
| Lebanon, Tennessee, United States, 37087 | |
| The Sarah Cannon Cancer Center/Tennessee Oncology, PLLC | |
| Smyma, Tennessee, United States, 37167 | |
| Memorial Hospital | |
| Chattanooga, Tennessee, United States, 37404 | |
| The Sarah Cannon Cancer Center/Tennessee Oncology, PLLC | |
| Nashville, Tennessee, United States, 37211 | |
| Saint Mary's Health System, Inc. | |
| Knoxville, Tennessee, United States, 37917 | |
| Hall and Martin, M.D.'s, P.C. | |
| Knoxville, Tennessee, United States, 37920 | |
| The Consultant Group | |
| Franklin, Tennessee, United States, 37067 | |
| United States, Texas | |
| Arlington Cancer Center | |
| Arlington, Texas, United States, 76012 | |
| Univ. of TX, MD Anderson Cancer Center | |
| Houston, Texas, United States, 77030 | |
| Dallas Oncology Consultants | |
| Dallas, Texas, United States, 75201 | |
| Texas Oncology, PA | |
| Fort Worth, Texas, United States, 76104 | |
| Southwest Fort Worth Cancer Center | |
| Fort Worth, Texas, United States, 76132 | |
| Amarillo Cancer Center | |
| Amarillo, Texas, United States, 79106 | |
| Texas Cancer Associates | |
| Dallas, Texas, United States, 75231 | |
| United States, Virginia | |
| Danville Hematology and Oncology, Inc. | |
| Danville, Virginia, United States, 24541 | |
| United States, Washington | |
| Western Washington Oncology | |
| Olympia, Washington, United States, 98502 | |
| MultiCare Health System - Medical Oncology | |
| Tacoma, Washington, United States, 98405 | |
| Western Washington Oncology | |
| Olympia, Washington, United States, 98506 | |
| Western Washington Oncology | |
| Centralia, Washington, United States, 98531 | |
| Western Washington Oncology | |
| Shelton, Washington, United States, 98584 | |
| Western Washington Oncology | |
| Aberdeen, Washington, United States, 98520 | |
| Allenmore Hospital - Hematology Oncology Clinic | |
| Tacoma, Washington, United States, 98405 | |
| Covington Multicare - Oncology Clinic | |
| Covington, Washington, United States, 98042 | |
| United States, Wisconsin | |
| Medical Consultants, Ltd. | |
| Milwaukee, Wisconsin, United States, 53215 | |
| Marshfield Clinic Research Foundation | |
| Marshfield, Wisconsin, United States, 54449 | |
| Saint Joseph's Hospital | |
| Marshfield, Wisconsin, United States, 54449 | |
| Chippewa Falls Cancer Center | |
| Chippewa Falls, Wisconsin, United States, 54729 | |
| Merrill Cancer Center | |
| Merrill, Wisconsin, United States, 54452 | |
| Wausau Cancer Center | |
| Wausau, Wisconsin, United States, 54401 | |
| Marshfield Clinc - Lakeland Center | |
| Minocqua, Wisconsin, United States, 54548 | |
| Regional Cancer Center | |
| Eau Claire, Wisconsin, United States, 54701 | |
| Saint Michael Hospital | |
| Stevens Point, Wisconsin, United States, 54481 | |
| Marshfield Clinic - Indianhead Center | |
| Rice Lake, Wisconsin, United States, 54868 | |
| Wisconsin Rapid Cancer Center | |
| Marshfield, Wisconsin, United States, 54494 | |
| Marshfield Clinic - Lakeland Center | |
| Minocqua, Wisconsin, United States, 54548 | |
| Diagnostic Radiology Associates | |
| Rice Lake, Wisconsin, United States, 54868 | |
| Lakeview Medical Center | |
| Rice Lake, Wisconsin, United States, 54868 | |
| United States, Wyoming | |
| Hematology Oncology Centers of the Northern Rockies | |
| Cody, Wyoming, United States, 82414 | |
| Hematology Oncology of the Northern Rockies | |
| Sheridan, Wyoming, United States, 82801 | |
| Argentina | |
| Complejo Medico de la Policia Federal Argentina "Churruca-Visca" | |
| Buenos Aires, Argentina, C1437JCP | |
| Hospital Donacion Francisco Santojanni | |
| Buenos Aires, Argentina, 1408 | |
| Complejo Medico de la Policia Federal Argentina "Churruca-Visca" | |
| Buenos Aires, Argentina, 1437 | |
| Sanatorio Municipal Dr. Julio Mendez | |
| Buenos Aires, Argentina, C1405CNF | |
| Sociedad de Beneficencia Hospital Italiano | |
| Cordoba, Argentina | |
| Hospital General de Agudos "Carlos G. Durand" | |
| Buenos Aires, Argentina, C1405DCS | |
| Hospital Italiano de Buenos Aires | |
| Buenos Aires, Argentina, C1181ACH | |
| Policlinica Privada Instituto de Medicina Nuclear | |
| Buenos Aires, Argentina | |
| Hospital de Oncologia Maria Curie | |
| Buenos Aires, Argentina | |
| ISIS Clinica Especializada | |
| Santa Fe, Argentina, 03000 | |
| Argentina, Buenos Aires | |
| Hospital General de Agudos Donacion F. Santojanni | |
| Capital Federal, Buenos Aires, Argentina, 1408 | |
| Hospital Universitario Austral | |
| Pilar, Buenos Aires, Argentina, B1629AHJ | |
| Hospital Italiano Regional del Sur | |
| Bahia Blanca, Buenos Aires, Argentina, B8001HXM | |
| Belgium | |
| Cliniques Universitaires Saint-Luc | |
| Brussels, Belgium, B 1200 | |
| Universitair Ziekenhuis Gent. | |
| Gent, Belgium, 9000 | |
| AZ-VUB Dienst Oncologie | |
| Brussels, Belgium, 1090 | |
| Centre Hospitalier Regional de la Citadelle | |
| Liege, Belgium, 4000 | |
| Belgium, Antwerpen | |
| Algemeen Ziekenhuis Antwerpen | |
| Lindedreef, Antwerpen, Belgium, 2020 | |
| Belgium, Edegem | |
| Universitaire Ziekenhuis Antwerpen | |
| Wilrijkstraat, Edegem, Belgium, 2650 | |
| Belgium, Leuven | |
| University Hospital Gasthuisberg | |
| Herestraat, Leuven, Belgium, 49 | |
| Brazil | |
| INCA Hospital de Oncologia Clinica | |
| Rio de Janeiro, Brazil, 20220-410 | |
| Instituto de Saude e Bem Estar da Mulher | |
| Sao Paolo, Brazil | |
| Hospital do Cancer - A.C. Camargo | |
| Sao Paolo, Brazil, 01509 | |
| UNIFESP/EPM | |
| Sao Paulo, Brazil, 04024-002 | |
| Brazil, CE | |
| Instituto do Cancer do Ceara | |
| Fortaleza, CE, Brazil, 60430-230 | |
| Brazil, mg | |
| Hospital Vera Cruz | |
| Belo Horizonte, mg, Brazil, 30190-130 | |
| Hospital Luxemburgo | |
| Belo Horizonte, mg, Brazil, 32380 | |
| Brazil, Porto Alegre | |
| Hospital de Clinicas de Porto Alegre | |
| Bairro Bom Fim, Porto Alegre, Brazil, 90035-003 | |
| Brazil, PR | |
| Hospital de Clinicas da Universidade Federal do Parana | |
| Curitiba, PR, Brazil | |
| Centro de Tratamento Oncologico de Londrina | |
| Londrina, PR, Brazil, 86010-640 | |
| Brazil, SP | |
| Hospital das Clinicas de Sao Paulo-FMUSP | |
| Sao Paolo, SP, Brazil, 05403 | |
| Instituto Arnaldo Vieira de Carvalho | |
| Sao Paolo, SP, Brazil, 01223 | |
| Chile | |
| Clinica Santa Maria | |
| Santiago de Chile, Chile | |
| Chile, Santiago | |
| Servicio de Oncologia-Hospital Clinico Unversidad de Chile | |
| Independencia, Santiago, Chile, Santos Dumontt 999 | |
| Czech Republic | |
| Masarykuv Onkologicky Ustav | |
| Brno, Czech Republic, 656 53 | |
| Fakultni nemocnice, Onkologicka klinika | |
| Plzen, Czech Republic | |
| Czech Republic, Olomouc | |
| Fakultni nemocnice Olomouc, Onkologicka klinika | |
| Pardubice, Olomouc, Czech Republic, 77520 | |
| Czech Republic, Pardubice | |
| Krajska nemocnice Pardubice, Oddeleni radiacni onklogie | |
| Kyjevska 44, Pardubice, Czech Republic, 53203 | |
| Czech Republic, Plzen | |
| Fakultni Nemocnice - Onkologicka Klinika | |
| Doudlevecka 69, Plzen, Czech Republic, 301 31 | |
| Czech Republic, Praha | |
| Vseobecna Fakultni Nemocnice - Onkologicka Klinika | |
| Unemocnice, Praha, Czech Republic, 12808 | |
| Czech Republic, Zlin | |
| Batova krajska nemocnice Zlin, prispevkova organizace, Onkologicke oddeleni | |
| Havlickovo nabrezi 600, Zlin, Czech Republic, 76001 | |
| Batova krajska nemocnice Zlin, prispevkova organizace, Radiodiagnosticke oddeleni | |
| Havlickovo nabrezi, Zlin, Czech Republic, 76001 | |
| Germany | |
| St. Vincentius Kliniken - Radiology | |
| Karlsruhe, Germany, D76137 | |
| Klinikum GroBhadern-Zentrum fur Frauenheilkunde | |
| Munich, Germany, D81377 | |
| Klinikum GroBhadern-Institut fur Radiologie | |
| Munich, Germany, D-81377 | |
| St. Vincentius Kliniken - Frauenkinik | |
| Karlsruhe, Germany, D76137 | |
| Universitaets-Frauenklinik Ulm | |
| Ulm, Germany, D89075 | |
| Dr. Horst-Schmidt-Kliniken GmbH | |
| Wiesbaden, Germany, D65199 | |
| Universitatsklinikum Charite - Campus Virchow-Klinikum | |
| Berlin, Germany, D13353 | |
| St. Vincentius Kliniken | |
| Karlsruhe, Germany, D-76137 | |
| Hungary | |
| SZTE, Department of Oncotherapy | |
| Szeged, Hungary, 6720 | |
| Baranya County Hospital - Department of Oncology | |
| Rakoczi, Hungary | |
| Baranya County Hospital | |
| Pecs, Hungary, 7632 | |
| Uzsoki Street Hospital Dept. of Radiooncology | |
| Budapest, Hungary, H-1145 | |
| Semmelweis University, 1st Dept. of Obstetrics and Gynaecology | |
| Baross, Hungary, H-1088 | |
| Faculty of Gynaecologycal Oncology/Univ. of Debrecen | |
| Debrecen, Hungary, 4032 | |
| Baranya County Hospital - Department of Radiology | |
| Rakoczi, Hungary | |
| Ireland | |
| Oncology Dept., University Floor, Belfast City Hospital | |
| Belfast, Ireland, BT9 7AB | |
| Netherlands | |
| Vrije Universiteit Medical Centre (VUMC) | |
| HV Amsterdam, Netherlands, 1081 | |
| University Medical Centre Nijmegen (UMCN) | |
| Nijmegen, Netherlands, 6525 | |
| South Africa | |
| Eastern Cape Oncology Research Centre | |
| Port Elizabeth, South Africa, 6001 | |
| South Africa, Cape Town | |
| Panorama Medical Centre | |
| Panorama, Cape Town, South Africa, 7500 | |
| South Africa, Durban | |
| Hopelands Cancer Centre | |
| Overport, Durban, South Africa, 4091 | |
| South Africa, Johannesburg | |
| Rosebank Oncology Centre | |
| Saxonwold, Johannesburg, South Africa, 2196 | |
| Medical and Dental Centre | |
| Rosebank, Johannesburg, South Africa, 2196 | |
| South Africa, Pretoria | |
| Wilgers Oncology Centre | |
| Die Wilgers x14, Pretoria, South Africa, 41 | |
| Spain | |
| Servicio de Oncologia | |
| Madrid, Spain, 28007 | |
| Hospital Clinic i Provincial | |
| Barcelona, Spain, 8035 | |
| Hospital General de Guadalajara | |
| Guadalajara, Spain | |
| Instituto Valenciano de Oncologia (IVO) Servicio de Oncologia | |
| Valencia, Spain, 46009 | |
| Instituto Valenciano de Oncologia (IVO) Servicio de Radiologia | |
| Valencia, Spain, 46009 | |
| Hospital Clinic i Provincial de Barcelona - Servicio de Oncologia Medica | |
| Barcelona, Spain, 08036 | |
| Spain, Barcelona | |
| Servicio Oncologia Hospital General Vall d'HebronPaseo | |
| Vall d'Hebron, Barcelona, Spain, 119-129 | |
| Spain, Valencia | |
| Instituto Valenciano de Oncologia (IVO) | |
| Profesor Beltran Baguena, Valencia, Spain, 46009 | |
| United Kingdom | |
| Department of Medical Oncology, Christie Hospital | |
| Manchester, United Kingdom, M20 4BX | |
| St. Chad's Outpatients Unit, City Hospital | |
| Birmingham, United Kingdom, B18 7QH | |
| Beatson Oncology Centre | |
| Glasgow, United Kingdom, G11 6NT | |
| Medical Oncology (NCCT) - Newcastle General Hospital | |
| Newcastle-upon-Tyne, United Kingdom, NE4 6BE | |
| Medical Oncology - Guy's and St. Thomas' Hospital | |
| London, United Kingdom, SE1 9RT | |
| Dorset Cancer Centre - Poole Hospital | |
| Poole, United Kingdom, BH15 2JB | |
| Beatson Oncology Unit | |
| Glasgow, United Kingdom, G11 6NT | |
| United Bristol Healthcare Trust - Bristol Oncology Centre | |
| Bristol, United Kingdom, BS2 8ED | |
| Velindre NHS Trust - Velindre Hospital | |
| Wales, United Kingdom, CFT142TL | |
| Department of Medicine-Royal Marsden Hospital | |
| London, United Kingdom, SW3 6JJ | |
| United Kingdom, Dundee | |
| Department of Cancer Medicine - Ninewells Hospital & Medical School | |
| Scotland, Dundee, United Kingdom, DD1 9SY | |
| United Kingdom, Surrey | |
| Dept. of Med. Oncology/The Royal Marsden Hospital | |
| Sutton, Surrey, United Kingdom, SMT 5PT | |
More Information
| Study ID Numbers: | TLK286.3017 |
| Study First Received: | April 7, 2003 |
| Last Updated: | January 10, 2008 |
| ClinicalTrials.gov Identifier: | NCT00057720 History of Changes |
| Health Authority: | United States: Food and Drug Administration |
|
ovary |
|
Ovarian Neoplasms Molecular Mechanisms of Pharmacological Action Antineoplastic Agents Gonadal Disorders Genital Neoplasms, Female Endocrine System Diseases Enzyme Inhibitors Urogenital Neoplasms Ovarian Diseases Antibiotics, Antineoplastic |
Pharmacologic Actions Doxorubicin Adnexal Diseases Genital Diseases, Female Neoplasms Neoplasms by Site Therapeutic Uses Topotecan Endocrine Gland Neoplasms |
