DISEASE CHARACTERISTICS:

• Histologically or pathologically confirmed ovarian epithelial, primary peritoneal, or fallopian tube cancer

  • No mixed mullerian and borderline ovarian tumors
• Surgically staged as stage III or IV at initial diagnosis

• Must meet one of the following criteria for refractory/relapsed disease:

  • Relapsed within 6 months after completing front-line concurrent or sequential platinum (either cisplatin or carboplatin) and taxane (paclitaxel or docetaxel) chemotherapy

  • Had a best response of increasing disease during this front-line regimen

    • Consolidation chemotherapy and reinduction therapy are counted as part of the front-line regimen

• Unidimensionally measurable disease

  • At least 2 cm by medical photograph (skin or oral lesion), palpation, plain x-ray, CT scan, MRI, or other conventional technique (bone lesions not included)
  • At least 1 cm by spiral CT scan
  • Measurable disease must remain outside of radiotherapy field
• If the tumor is known to be KIT (CD117) or PDGFR positive, patient must be offered SWOG-S0211 if available

PATIENT CHARACTERISTICS:

Age

• Not specified

Performance status

• Zubrod 0-2

Life expectancy

• Not specified

Hematopoietic

• Not specified

Hepatic

• Not specified

Renal

• Not specified

Cardiovascular

• No myocardial infarction within the past 6 months
• No angina pectoris
• No uncontrolled congestive heart failure
• No uncontrolled cardiac arrhythmia

Other

• Not pregnant or nursing
• Negative pregnancy test
• Fertile patients must use effective contraception

• No other malignancy within the past 5 years except for the following:

  • Adequately treated basal cell or squamous cell skin cancer
  • Carcinoma in situ of the cervix
  • Adequately treated stage I or II cancer from which the patient is currently in complete remission

PRIOR CONCURRENT THERAPY:

Biologic therapy

• No more than 1 prior biological response modifier
• At least 28 days since prior biological response modifier and recovered

Chemotherapy

• See Disease Characteristics
• No prior topotecan or other topoisomerase I inhibitor
• One other additional prior chemotherapy regimen allowed
• At least 28 days since prior chemotherapy (14 days for weekly chemotherapy) and recovered

Endocrine therapy

• Prior hormonal therapy allowed
• No concurrent hormonal therapy

Radiotherapy

• At least 28 days since prior radiotherapy and recovered
• No prior radiotherapy to more than 25% of bone marrow
• No concurrent palliative radiotherapy

Surgery

• At least 14 days since prior major surgery and recovered

Other

• At least 28 days since prior investigational drugs and recovered
• No other concurrent antitumor therapy