DISEASE CHARACTERISTICS:

• Histologically or cytologically confirmed unresectable primary (M0) or metastatic renal cell cancer

• At least 1 unidimensionally measurable lesion

  • At least 20 mm by conventional techniques OR
  • At least 10 mm by spiral CT scan
  • Soft tissue disease that has been previously irradiated within the past 2 months is not considered measurable
  • Soft tissue disease within a previously irradiated field is considered measurable provided disease has progressed and other measurable disease exists outside of the radiation field
• No prior or concurrent brain metastases

PATIENT CHARACTERISTICS:

Age:

• Not specified

Performance status:

• Zubrod 0-2

Life expectancy:

• Not specified

Hematopoietic:

• No hypercoagulable state other than renal cell cancer

Hepatic:

• Not specified

Renal:

• Not specified

Cardiovascular:

• No symptomatic congestive heart failure
• No unstable angina pectoris
• No cardiac arrhythmia
• No prior isolated occurrence of deep venous thrombosis within the past 6 months

Pulmonary:

• No prior isolated occurrence of pulmonary embolism within the past 6 months

Other:

• No other malignancy within the past 5 years except adequately treated basal cell or squamous cell skin cancer, carcinoma in situ of the cervix, or stage I or II cancer in complete remission
• No history of allergic reactions to compounds of similar chemical or biologic composition to flavopiridol (e.g., staurosporine, deschloroflavopiridol, or butyrolactone I)
• No other uncontrolled illness (e.g., diabetes mellitus)
• No ongoing or active infection
• No psychiatric illness or social situation that would preclude study compliance
• Not pregnant or nursing
• Negative pregnancy test
• Fertile patients must use effective contraception

PRIOR CONCURRENT THERAPY:

Biologic therapy:

• 1 prior immunotherapy regimen comprising interferon and/or interleukin-2 allowed
• At least 28 days since prior immunotherapy and recovered
• No concurrent prophylactic filgrastim (G-CSF)

Chemotherapy:

• No prior chemotherapy for renal cell cancer

Endocrine therapy:

• Not specified

Radiotherapy:

• See Disease Characteristics
• At least 21 days since prior radiotherapy and recovered

Surgery:

• See Disease Characteristics
• Prior resection of primary tumor allowed
• At least 28 days since prior surgery and recovered