|
|
Home
Search
Study Topics
Glossary
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
||||||||||||||||||||||||||||||||||||
| Sponsor: | Southwest Oncology Group |
|---|---|
| Collaborators: |
National Cancer Institute (NCI) Eastern Cooperative Oncology Group North Central Cancer Treatment Group Radiation Therapy Oncology Group |
| Information provided by: | National Cancer Institute (NCI) |
| ClinicalTrials.gov Identifier: | NCT00004011 |
Purpose
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. It is not yet known if surgery plus combination chemotherapy is more effective than surgery alone for non-small cell lung cancer.
PURPOSE: Randomized phase III trial to compare the effectiveness of surgery with or without combination chemotherapy in treating patients who have non-small cell lung cancer.
| Condition | Intervention | Phase |
|---|---|---|
|
Lung Cancer |
Drug: carboplatin Drug: paclitaxel Procedure: conventional surgery |
Phase III |
| Study Type: | Interventional |
| Study Design: | Treatment, Randomized, Active Control |
| Official Title: | A Randomized Phase III Trial of Surgery Alone or Surgery Plus Preoperative Paclitaxel/Carboplatin in Clinical Stage IB (T2N0), II (T1-2N1, T3N0) and Selected IIIA (T3N1) Non-Small Cell Lung Cancer (NSCLC) |
| Study Start Date: | October 1999 |
OBJECTIVES:
OUTLINE: This is a randomized, multicenter study. Patients are stratified according to clinical stage (IB or IIA vs IIB or IIIA).
Patients are randomized to one of two treatment arms:
Patients are followed every 3 months for 1 year, every 6 months for 5 years, and then annually until year 10.
PROJECTED ACCRUAL: A total of 600 patients (300 per treatment arm) will be accrued for this study within 4 years.
Eligibility| Ages Eligible for Study: | 18 Years and older |
| Genders Eligible for Study: | Both |
| Accepts Healthy Volunteers: | No |
DISEASE CHARACTERISTICS:
Histologically or cytologically proven non-small cell lung cancer (NSCLC), meeting 1 of the following staging criteria:
Stage II
Selected stage IIIA with negative mediastinoscopies
No symptomatic tumors (T3, N0 or T3, N1) involving the superior sulcus
Bidimensionally measurable or evaluable disease by chest x-ray or contrast-enhanced CT scan
PATIENT CHARACTERISTICS:
Age:
Performance status:
Life expectancy:
Hematopoietic:
Hepatic:
Renal:
Pulmonary:
Other:
PRIOR CONCURRENT THERAPY:
Biologic therapy:
Chemotherapy:
Endocrine therapy:
Radiotherapy:
Surgery:
Other:
Contacts and Locations
Hide Study Locations| United States, Alabama | |
| Comprehensive Cancer Institute | |
| Huntsville, Alabama, United States, 35801 | |
| DCH Cancer Treatment Center | |
| Tuscaloosa, Alabama, United States, 35401 | |
| Huntsville Hospital | |
| Huntsville, Alabama, United States, 35807 | |
| MBCCOP - Gulf Coast | |
| Mobile, Alabama, United States, 36607 | |
| Montgomery Cancer Center | |
| Montgomery, Alabama, United States, 36106-3657 | |
| Radiation Oncology Associates of West Alabama | |
| Tuscaloosa, Alabama, United States, 35401 | |
| University of Alabama at Birmingham Comprehensive Cancer Center | |
| Birmingham, Alabama, United States, 35294-3300 | |
| United States, Arizona | |
| CCOP - Mayo Clinic Scottsdale Oncology Program | |
| Scottsdale, Arizona, United States, 85259-5404 | |
| Foundation for Cancer Research and Education | |
| Phoenix, Arizona, United States, 85013 | |
| United States, California | |
| California Cancer Center | |
| Fresno, California, United States, 93720 | |
| CCOP - Bay Area Tumor Institute | |
| Oakland, California, United States, 94609-3305 | |
| CCOP - Santa Rosa Memorial Hospital | |
| Santa Rosa, California, United States, 95403 | |
| David Grant Medical Center | |
| Travis Air Force Base, California, United States, 94535 | |
| Mount Diablo Medical Center | |
| Concord, California, United States, 94524-4110 | |
| Jonsson Comprehensive Cancer Center, UCLA | |
| Los Angeles, California, United States, 90095-1714 | |
| Loma Linda University Cancer Institute at Loma Linda University Medical Center | |
| Loma Linda, California, United States, 92354 | |
| Huntington Cancer Center at Huntington Hospital | |
| Pasadena, California, United States, 91105 | |
| Naval Medical Center - San Diego | |
| San Diego, California, United States, 92134-3202 | |
| O'Connor Hospital | |
| San Jose, California, United States, 95128 | |
| Providence Saint Joseph Medical Center - Burbank | |
| Burbank, California, United States, 91505 | |
| Radiation Medical Group, Incorporated | |
| San Diego, California, United States, 92101 | |
| Radiation Oncology Centers - Sacramento | |
| Sacramento, California, United States, 95816 | |
| Sutter Health Western Division Cancer Research Group | |
| Greenbrae, California, United States, 94904 | |
| Saint Agnes Cancer Center | |
| Fresno, California, United States, 93720 | |
| Stanford Cancer Center at Stanford University Medical Center | |
| Stanford, California, United States, 94305-5408 | |
| Robert and Beverly Lewis Family Cancer Care Center at Pomona Valley Hospital Medical Center | |
| Pomona, California, United States, 91767 | |
| Torrance Memorial Medical Center | |
| Torrance, California, United States, 90505 | |
| UCSF Comprehensive Cancer Center | |
| San Francisco, California, United States, 94115 | |
| USC/Norris Comprehensive Cancer Center and Hospital | |
| Los Angeles, California, United States, 90033-0804 | |
| Veterans Affairs Medical Center - Long Beach | |
| Long Beach, California, United States, 90822 | |
| United States, Colorado | |
| CCOP - Colorado Cancer Research Program, Incorporated | |
| Denver, Colorado, United States, 80224 | |
| Memorial Hospital Cancer Center | |
| Colorado Springs, Colorado, United States, 80909 | |
| St. Mary's Regional Cancer Center at St. Mary's Hospital and Medical Center | |
| Grand Junction, Colorado, United States, 81502-1628 | |
| University of Colorado Cancer Center at University of Colorado Health Sciences Center | |
| Denver, Colorado, United States, 80010 | |
| United States, Connecticut | |
| Hospital of St. Raphael | |
| New Haven, Connecticut, United States, 06511 | |
| Yale Comprehensive Cancer Center | |
| New Haven, Connecticut, United States, 06520-8040 | |
| United States, Delaware | |
| CCOP - Christiana Care Health Services | |
| Newark, Delaware, United States, 19713 | |
| United States, District of Columbia | |
| Sibley Memorial Hospital | |
| Washington, District of Columbia, United States, 20016 | |
| United States, Florida | |
| 21st Century Oncology - Fort Myers | |
| Fort Myers, Florida, United States, 33901-8082 | |
| Baptist Hospital of Miami | |
| Miami, Florida, United States, 33176-2197 | |
| Bay Medical Center | |
| Panama City, Florida, United States, 32401 | |
| CCOP - Mount Sinai Medical Center | |
| Miami Beach, Florida, United States, 33140 | |
| Florida Radiation Oncology Group | |
| Jacksonville, Florida, United States, 32207 | |
| Gulf Coast Cancer Treatment Center | |
| Panama City, Florida, United States, 32405-4587 | |
| University of Miami Sylvester Cancer Center | |
| Miami, Florida, United States, 33136 | |
| Halifax Medical Center | |
| Daytona Beach, Florida, United States, 32114 | |
| Holmes Regional Medical Center | |
| Melbourne, Florida, United States, 32901-3276 | |
| Mayo Clinic - Jacksonville | |
| Jacksonville, Florida, United States, 32224 | |
| MD Anderson Cancer Center Orlando | |
| Orlando, Florida, United States, 32806-2134 | |
| Sarasota Radiation and Medical Oncology Center | |
| Sarasota, Florida, United States, 34233 | |
| Shands Cancer Center at the University of Florida Health Science Center | |
| Gainesville, Florida, United States, 32610-0385 | |
| Tallahassee Memorial Hospital | |
| Tallahassee, Florida, United States, 32308 | |
| H. Lee Moffitt Cancer Center and Research Institute | |
| Tampa, Florida, United States, 33612-9497 | |
| United States, Georgia | |
| CCOP - Atlanta Regional | |
| Atlanta, Georgia, United States, 30342-1701 | |
| Medical Center/John B. Amos Community Cancer Center | |
| Columbus, Georgia, United States, 31901 | |
| Regional Radiation Oncology Center at Rome | |
| Rome, Georgia, United States, 30165 | |
| Veterans Affairs Medical Center - Atlanta (Decatur) | |
| Decatur, Georgia, United States, 30033 | |
| Winship Cancer Institute of Emory University | |
| Atlanta, Georgia, United States, 30322 | |
| United States, Hawaii | |
| MBCCOP - Hawaii | |
| Honolulu, Hawaii, United States, 96813 | |
| United States, Illinois | |
| Cancer Care Center at Advocate Good Samaritan Hospital | |
| Downers Grove, Illinois, United States, 60515 | |
| Cardinal Bernardin Cancer Center at Loyola University Medical Center | |
| Maywood, Illinois, United States, 60153 | |
| CCOP - Carle Cancer Center | |
| Urbana, Illinois, United States, 61801 | |
| CCOP - Central Illinois | |
| Decatur, Illinois, United States, 62526 | |
| CCOP - Illinois Oncology Research Association | |
| Peoria, Illinois, United States, 61602 | |
| CCOP - Scott and White Hospital | |
| Peoria, Illinois, United States, 61602 | |
| Ingalls Memorial Hospital | |
| Harvey, Illinois, United States, 60426 | |
| Lutheran General Cancer Care Center | |
| Park Ridge, Illinois, United States, 60068 | |
| Methodist Medical Center of Illinois | |
| Peoria, Illinois, United States, 61636 | |
| Northwest Community Hospital | |
| Arlington Heights, Illinois, United States, 60005 | |
| Robert H. Lurie Comprehensive Cancer Center at Northwestern University | |
| Chicago, Illinois, United States, 60611 | |
| United States, Indiana | |
| Ball Memorial Hospital Cancer Center | |
| Muncie, Indiana, United States, 47303-3499 | |
| Bloomington Hospital | |
| Bloomington, Indiana, United States, 47402 | |
| CCOP - Northern Indiana CR Consortium | |
| South Bend, Indiana, United States, 46601 | |
| Community Regional Cancer Care | |
| Indianapolis, Indiana, United States, 46219 | |
| Indiana University Cancer Center | |
| Indianapolis, Indiana, United States, 46202-5289 | |
| Methodist Cancer Center at Methodist Hospital | |
| Indianapolis, Indiana, United States, 46206-1367 | |
| St. John's Cancer Center at St. John's Medical Center | |
| Anderson, Indiana, United States, 46016 | |
| Veterans Affairs Medical Center - Indianapolis (Roudebush) | |
| Indianapolis, Indiana, United States, 46202 | |
| United States, Iowa | |
| CCOP - Cedar Rapids Oncology Project | |
| Cedar Rapids, Iowa, United States, 52403-1206 | |
| CCOP - Iowa Oncology Research Association | |
| Des Moines, Iowa, United States, 50309-1016 | |
| Siouxland Hematology-Oncology | |
| Sioux City, Iowa, United States, 51101-1733 | |
| Wendt Regional Cancer Center of Finley Hospital | |
| Dubuque, Iowa, United States, 52001 | |
| United States, Kansas | |
| CCOP - Wichita | |
| Wichita, Kansas, United States, 67214-3882 | |
| United States, Kentucky | |
| Central Baptist Hospital | |
| Lexington, Kentucky, United States, 40503 | |
| James Graham Brown Cancer Center at University of Louisville | |
| Louisville, Kentucky, United States, 40202 | |
| St. Elizabeth Medical Center | |
| Edgewood, Kentucky, United States, 41017 | |
| Markey Cancer Center at University of Kentucky Chandler Medical Center | |
| Lexington, Kentucky, United States, 40536-0293 | |
| Merle M. Mahr Cancer Center at Regional Medical Center of Hopkins County | |
| Madisonville, Kentucky, United States, 42431 | |
| Louisville Radiation Oncology Center at Caritas Regional Cancer Center | |
| Louisville, Kentucky, United States, 40215 | |
| United States, Louisiana | |
| CCOP - Ochsner | |
| New Orleans, Louisiana, United States, 70121 | |
| Mary Bird Perkins Cancer Center | |
| Baton Rouge, Louisiana, United States, 70809 | |
| MBCCOP - LSU Health Sciences Center | |
| New Orleans, Louisiana, United States, 70112 | |
| Tulane Cancer Center at Tulane University Hospital and Clinic | |
| New Orleans, Louisiana, United States, 70112-2699 | |
| United States, Maine | |
| Maine Medical Center | |
| Portland, Maine, United States, 04102 | |
| United States, Maryland | |
| Harbor Hospital Center | |
| Baltimore, Maryland, United States, 21215-1290 | |
| Greater Baltimore Medical Center and Cancer Center | |
| Baltimore, Maryland, United States, 21204 | |
| Greenebaum Cancer Center at University of Maryland Medical Center | |
| Baltimore, Maryland, United States, 21201 | |
| Anne Arundel Oncology Center | |
| Annapolis, Maryland, United States, 21401 | |
| Peninsula Regional Medical Center | |
| Salisbury, Maryland, United States, 21801 | |
| Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | |
| Baltimore, Maryland, United States, 21231-2410 | |
| Sinai Hospital of Baltimore | |
| Baltimore, Maryland, United States, 21215 | |
| St. Agnes Cancer Center | |
| Baltimore, Maryland, United States, 21229 | |
| United States, Massachusetts | |
| Beth Israel Deaconess Medical Center | |
| Boston, Massachusetts, United States, 02215 | |
| NSMC Cancer Center | |
| Peabody, Massachusetts, United States, 01960 | |
| Cape Cod Hospital | |
| Hyannis, Massachusetts, United States, 02601 | |
| Dana-Farber/Harvard Cancer Center at Dana Farber Cancer Institute | |
| Boston, Massachusetts, United States, 02114 | |
| Cancer Research Center at Boston Medical Center | |
| Boston, Massachusetts, United States, 02118 | |
| Tufts - New England Medical Center | |
| Boston, Massachusetts, United States, 02111 | |
| Veterans Affairs Medical Center - Boston (Jamaica Plain) | |
| Jamaica Plain, Massachusetts, United States, 02130 | |
| United States, Michigan | |
| Barbara Ann Karmanos Cancer Institute | |
| Detroit, Michigan, United States, 48201 | |
| CCOP - Beaumont | |
| Royal Oak, Michigan, United States, 48073-6769 | |
| CCOP - Kalamazoo | |
| Kalamazoo, Michigan, United States, 49007-3731 | |
| Marquette General Hospital | |
| Marquette, Michigan, United States, 49855 | |
| Hurley Medical Center | |
| Flint, Michigan, United States, 48503 | |
| Josephine Ford Cancer Center at Henry Ford Hospital | |
| Detroit, Michigan, United States, 48202 | |
| CCOP - Michigan Cancer Research Consortium | |
| Ann Arbor, Michigan, United States, 48106 | |
| McLaren Regional Cancer Center | |
| Flint, Michigan, United States, 48532-3685 | |
| MidMichigan Medical Center - Midland | |
| Midland, Michigan, United States, 48670 | |
| University of Michigan Comprehensive Cancer Center | |
| Ann Arbor, Michigan, United States, 48109-0010 | |
| William Beaumont Hospital - Royal Oak | |
| Royal Oak, Michigan, United States, 48073 | |
| William Beaumont Hospital - Troy | |
| Troy, Michigan, United States, 48085 | |
| United States, Minnesota | |
| Fairview University Medical Center - University Campus | |
| Minneapolis, Minnesota, United States, 55455 | |
| CCOP - Metro-Minnesota | |
| Saint Louis Park, Minnesota, United States, 55416 | |
| Coborn Cancer Center | |
| Saint Cloud, Minnesota, United States, 56303 | |
| CCOP - Duluth | |
| Duluth, Minnesota, United States, 55805 | |
| Mayo Clinic Cancer Center | |
| Rochester, Minnesota, United States, 55905-0001 | |
| Veterans Affairs Medical Center - Minneapolis | |
| Minneapolis, Minnesota, United States, 55417-2399 | |
| United States, Missouri | |
| Cancer Research for the Ozarks | |
| Springfield, Missouri, United States, 65807 | |
| CCOP - Cancer Research for the Ozarks | |
| Springfield, Missouri, United States, 65807 | |
| CCOP - Kansas City | |
| Kansas City, Missouri, United States, 64131 | |
| Ellis Fischel Cancer Center at University of Missouri - Columbia | |
| Columbia, Missouri, United States, 65203 | |
| Siteman Cancer Center | |
| St. Louis, Missouri, United States, 63110 | |
| St. Louis University Hospital Cancer Center | |
| Saint Louis, Missouri, United States, 63110-0250 | |
| United States, Montana | |
| CCOP - Montana Cancer Consortium | |
| Billings, Montana, United States, 59101 | |
| United States, Nebraska | |
| CCOP - Missouri Valley Cancer Consortium | |
| Omaha, Nebraska, United States, 68106 | |
| Methodist Hospital Cancer Center at Nebraska Methodist Hospital - Omaha | |
| Omaha, Nebraska, United States, 68114-4199 | |
| UNMC Eppley Cancer Center at the University of Nebraska Medical Center | |
| Omaha, Nebraska, United States, 68198-7521 | |
| United States, Nevada | |
| CCOP - Southern Nevada Cancer Research Foundation | |
| Las Vegas, Nevada, United States, 89106 | |
| Comprehensive Cancer Centers of Nevada | |
| Las Vegas, Nevada, United States, 89109 | |
| United States, New Hampshire | |
| Elliot Regional Cancer Center | |
| Manchester, New Hampshire, United States, 03103 | |
| Norris Cotton Cancer Center at Dartmouth-Hitchcock Medical Center | |
| Lebanon, New Hampshire, United States, 03756-0002 | |
| United States, New Jersey | |
| Associated Radiologists, P.A. | |
| Warren, New Jersey, United States, 07059 | |
| Atlantic City Medical Center | |
| Pomona, New Jersey, United States, 08240 | |
| Cancer Institute of New Jersey | |
| New Brunswick, New Jersey, United States, 08903 | |
| Community Medical Center | |
| Toms River, New Jersey, United States, 08755 | |
| Fox Chase Cancer Center at St. Francis Medical Center | |
| Trenton, New Jersey, United States, 08629 | |
| Fox Chase Virtua Health Cancer Program at Virtua Memorial Hospital | |
| Mount Holly, New Jersey, United States, 08060 | |
| John F. Kennedy Medical Center | |
| Edison, New Jersey, United States, 08818 | |
| South Jersey Regional Cancer Center | |
| Millville, New Jersey, United States, 08332 | |
| Monmouth Medical Center | |
| Long Branch, New Jersey, United States, 07740-6395 | |
| Newark Beth Israel Medical Center | |
| Newark, New Jersey, United States, 07112 | |
| Medical Center of Princeton | |
| Princeton, New Jersey, United States, 08540 | |
| Trinitas Hospital - Jersey Street Campus | |
| Elizabeth, New Jersey, United States, 07201 | |
| Valley Hospital | |
| Ridgewood, New Jersey, United States, 07450 | |
| Veterans Affairs Medical Center - East Orange | |
| East Orange, New Jersey, United States, 07019 | |
| United States, New Mexico | |
| Radiation Oncology Associates of Albuquerque | |
| Albuquerque, New Mexico, United States, 87109 | |
| United States, New York | |
| Beth Israel Medical Center - Philipps Ambulatory Care Center | |
| New York, New York, United States, 10003 | |
| Champlain Valley Physicians Hospital Medical Center | |
| Plattsburgh, New York, United States, 12901-1490 | |
| CCOP - North Shore University Hospital | |
| Manhasset, New York, United States, 11030 | |
| CCOP - Syracuse Hematology-Oncology Associates of Central New York, P.C. | |
| East Syracuse, New York, United States, 13057 | |
| Cancer Center of Albany Medical Center | |
| Albany, New York, United States, 12208 | |
| Finger Lakes Radiation Oncology Center | |
| Clifton Springs, New York, United States, 14432 | |
| Herbert Irving Comprehensive Cancer Center at Columbia University | |
| New York, New York, United States, 10032 | |
| James P. Wilmot Cancer Center at University of Rochester Medical Center | |
| Rochester, New York, United States, 14642 | |
| MBCCOP-Our Lady of Mercy Cancer Center | |
| Bronx, New York, United States, 10466 | |
| Memorial Sloan-Kettering Cancer Center | |
| New York, New York, United States, 10021 | |
| SUNY Downstate Medical Center | |
| Brooklyn, New York, United States, 11203 | |
| Riverhill Radiation Oncology | |
| Yonkers, New York, United States, 10701 | |
| Roswell Park Cancer Institute | |
| Buffalo, New York, United States, 14263-0001 | |
| New York Methodist Hospital | |
| Brooklyn, New York, United States, 11215 | |
| Vassar Brothers Medical Center | |
| Poughkeepsie, New York, United States, 12601 | |
| United States, North Carolina | |
| Batte Cancer Center at Northeast Medical Center | |
| Concord, North Carolina, United States, 28025 | |
| CCOP - Southeast Cancer Control Consortium | |
| Winston-Salem, North Carolina, United States, 27104-4241 | |
| Comprehensive Cancer Center at Wake Forest University | |
| Winston-Salem, North Carolina, United States, 27157-1082 | |
| Leo W. Jenkins Cancer Center of University Health Systems of Eastern Carolina | |
| Greenville, North Carolina, United States, 27835-6028 | |
| Lineberger Comprehensive Cancer Center at University of North Carolina - Chapel Hill | |
| Chapel Hill, North Carolina, United States, 27599-7295 | |
| United States, North Dakota | |
| Altru Cancer Center | |
| Grand Forks, North Dakota, United States, 58201 | |
| CCOP - Merit Care Hospital | |
| Fargo, North Dakota, United States, 58122 | |
| Medcenter One Health System | |
| Bismarck, North Dakota, United States, 58501-5505 | |
| Trinity Cancer Care Center | |
| Minot, North Dakota, United States, 58701 | |
| United States, Ohio | |
| Akron City Hospital | |
| Akron, Ohio, United States, 44304 | |
| Akron General Medical Center | |
| Akron, Ohio, United States, 44302 | |
| Arthur G. James Cancer Hospital - Ohio State University | |
| Columbus, Ohio, United States, 43210-1240 | |
| Cancer Center at Christ Hospital | |
| Cincinnati, Ohio, United States, 45219 | |
| Charles M. Barrett Cancer Center at University Hospital | |
| Cincinnati, Ohio, United States, 45219 | |
| CCOP - Dayton | |
| Dayton, Ohio, United States, 45429 | |
| CCOP - Toledo Community Hospital | |
| Toledo, Ohio, United States, 43623-3456 | |
| CCOP - Columbus | |
| Columbus, Ohio, United States, 43206 | |
| Cleveland Clinic Taussig Cancer Center | |
| Cleveland, Ohio, United States, 44195 | |
| MetroHealth's Cancer Care Center at MetroHealth Medical Center | |
| Cleveland, Ohio, United States, 44106-5065 | |
| Parma Community General Hospital | |
| Parma, Ohio, United States, 44129 | |
| University Hospitals of Cleveland | |
| Cleveland, Ohio, United States, 44106 | |
| United States, Oklahoma | |
| CCOP - Oklahoma | |
| Tulsa, Oklahoma, United States, 74136 | |
| Frank C. Love Cancer Institute at St. Anthony Hospital | |
| Oklahoma City, Oklahoma, United States, 73102 | |
| Oklahoma University Medical Center | |
| Oklahoma City, Oklahoma, United States, 73104 | |
| St. John Health System | |
| Tulsa, Oklahoma, United States, 74104 | |
| United States, Oregon | |
| CCOP - Columbia River Oncology Program | |
| Portland, Oregon, United States, 97225 | |
| United States, Pennsylvania | |
| Reading Hospital and Medical Center | |
| Reading, Pennsylvania, United States, 19612-6052 | |
| Abramson Cancer Center at University of Pennsylvania Medical Center | |
| Philadelphia, Pennsylvania, United States, 19104 | |
| Albert Einstein Cancer Center | |
| Philadelphia, Pennsylvania, United States, 19141-3098 | |
| Allegheny General Hospital | |
| Pittsburgh, Pennsylvania, United States, 15212 | |
| CCOP - Geisinger Clinic and Medical Center | |
| Danville, Pennsylvania, United States, 17822-2001 | |
| CCOP - MainLine Health | |
| Wynnewood, Pennsylvania, United States, 19096 | |
| Dale and Frances Hughes Cancer Center | |
| East Stroudsburg, Pennsylvania, United States, 18301 | |
| Delaware County Memorial Hospital | |
| Drexel Hill, Pennsylvania, United States, 19026 | |
| Fox Chase Cancer Center | |
| Philadelphia, Pennsylvania, United States, 19111 | |
| Geisinger Medical Center | |
| Danville, Pennsylvania, United States, 17822-2001 | |
| Hillman Cancer Center at University of Pittsburgh Cancer Institute | |
| Pittsburgh, Pennsylvania, United States, 15236 | |
| John and Dorothy Morgan Cancer Center at Lehigh Valley Hospital | |
| Allentown, Pennsylvania, United States, 18105 | |
| Kimmel Cancer Center at Thomas Jefferson University - Philadelphia | |
| Philadelphia, Pennsylvania, United States, 19107-5541 | |
| Mercy Fitzgerald Hospital | |
| Darby, Pennsylvania, United States, 19023 | |
| Mercy Hospital Cancer Center - Scranton | |
| Scranton, Pennsylvania, United States, 18501 | |
| Mercy Hospital of Pittsburgh | |
| Pittsburgh, Pennsylvania, United States, 15219 | |
| Penn State Cancer Institute at Milton S. Hershey Medical Center | |
| Hershey, Pennsylvania, United States, 17033-0850 | |
| Abington Memorial Hospital | |
| Abington, Pennsylvania, United States, 19001 | |
| St. Luke's Hospital Cancer Center | |
| Bethlehem, Pennsylvania, United States, 18015 | |
| Veterans Affairs Medical Center - Philadelphia | |
| Philadelphia, Pennsylvania, United States, 19104 | |
| Wellspan Health - York Cancer Center | |
| York, Pennsylvania, United States, 17403 | |
| Western Pennsylvania Hospital | |
| Pittsburgh, Pennsylvania, United States, 15224 | |
| Wilkes-Barre General Hospital | |
| Wilkes-Barre, Pennsylvania, United States, 18764-0001 | |
| United States, Rhode Island | |
| Roger Williams Medical Center | |
| Providence, Rhode Island, United States, 02908-4735 | |
| United States, South Carolina | |
| CCOP - Greenville | |
| Greenville, South Carolina, United States, 29615 | |
| CCOP - Upstate Carolina | |
| Spartanburg, South Carolina, United States, 29303 | |
| United States, South Dakota | |
| CCOP - Sioux Community Cancer Consortium | |
| Sioux Falls, South Dakota, United States, 57104 | |
| Rapid City Regional Hospital | |
| Rapid City, South Dakota, United States, 57709 | |
| United States, Tennessee | |
| Vanderbilt-Ingram Cancer Center at Vanderbilt Medical Center | |
| Nashville, Tennessee, United States, 37232-5671 | |
| West Tennessee Cancer Center at Jackson-Madison County General Hospital | |
| Jackson, Tennessee, United States, 38301 | |
| United States, Texas | |
| Arlington Cancer Center | |
| Arlington, Texas, United States, 76012 | |
| Bayshore Medical Center | |
| Pasadena, Texas, United States, 77504 | |
| University of Texas Health Science Center at San Antonio | |
| San Antonio, Texas, United States, 78284-7811 | |
| Joe Arrington Cancer Research and Treatment Center | |
| Lubbock, Texas, United States, 79410-1894 | |
| University of Texas - MD Anderson Cancer Center | |
| Houston, Texas, United States, 77030-4009 | |
| Harrington Cancer Center | |
| Amarillo, Texas, United States, 79106 | |
| University of Texas Medical Branch | |
| Galveston, Texas, United States, 77555-0209 | |
| Wilford Hall Medical Center | |
| Lackland Air Force Base, Texas, United States, 78236-5300 | |
| United States, Utah | |
| Cottonwood Hospital Medical Center | |
| Murray, Utah, United States, 84107 | |
| Dixie Regional Medical Center | |
| Saint George, Utah, United States, 84770 | |
| LDS Hospital | |
| Salt Lake City, Utah, United States, 84143 | |
| University of Utah Health Sciences Center | |
| Salt Lake City, Utah, United States, 84132 | |
| Utah Valley Regional Medical Center - Provo | |
| Provo, Utah, United States, 84604 | |
| United States, Vermont | |
| Green Mountain Oncology Group | |
| Bennington, Vermont, United States, 05201 | |
| Vermont Cancer Center at University of Vermont | |
| Burlington, Vermont, United States, 05405-0075 | |
| United States, Virginia | |
| Bon Secours - St. Mary's Hospital | |
| Richmond, Virginia, United States, 23226 | |
| Cancer Center at the University of Virginia | |
| Charlottesville, Virginia, United States, 22908 | |
| Massey Cancer Center at Virginia Commonwealth University | |
| Richmond, Virginia, United States, 23298-0124 | |
| Naval Medical Center, Portsmouth | |
| Portsmouth, Virginia, United States, 23708-2197 | |
| RMH Regional Cancer Center | |
| Harrisonburg, Virginia, United States, 22801 | |
| United States, Washington | |
| Yakima Valley Memorial Hospital | |
| Yakima, Washington, United States, 98902 | |
| Deaconess Medical Center | |
| Spokane, Washington, United States, 99204 | |
| University Cancer Center at University of Washington Medical Center | |
| Seattle, Washington, United States, 98195-6043 | |
| Cancer Institute at Virginia Mason Medical Center | |
| Seattle, Washington, United States, 98111 | |
| United States, West Virginia | |
| Schiffler Cancer Center at Wheeling Hospital | |
| Wheeling, West Virginia, United States, 26003 | |
| United States, Wisconsin | |
| All Saints Cancer Center at All Saints Healthcare | |
| Racine, Wisconsin, United States, 53405 | |
| CCOP - Marshfield Clinic Research Foundation | |
| Marshfield, Wisconsin, United States, 54449 | |
| CCOP - St. Vincent Hospital Cancer Center, Green Bay | |
| Green Bay, Wisconsin, United States, 54307-3453 | |
| Columbia Hospital | |
| Milwaukee, Wisconsin, United States, 53211 | |
| Medical College of Wisconsin Cancer Center | |
| Milwaukee, Wisconsin, United States, 53226 | |
| Gundersen Lutheran Cancer Center at Gundersen Lutheran Medical Center | |
| La Crosse, Wisconsin, United States, 54601 | |
| Marshfield Clinic | |
| Marshfield, Wisconsin, United States, 54449 | |
| Community Memorial Hospital | |
| Menomonee Falls, Wisconsin, United States, 53051 | |
| Southern Wisconsin Radiotherapy Center | |
| Madison, Wisconsin, United States, 53713 | |
| St. Luke's Medical Center | |
| Milwaukee, Wisconsin, United States, 53215 | |
| St. Vincent Hospital | |
| Green Bay, Wisconsin, United States, 54307-3508 | |
| University of Wisconsin Comprehensive Cancer Center | |
| Madison, Wisconsin, United States, 53792-0001 | |
| Veterans Affairs Medical Center - Madison | |
| Madison, Wisconsin, United States, 53705 | |
| Veterans Affairs Medical Center - Milwaukee (Zablocki) | |
| Milwaukee, Wisconsin, United States, 53295 | |
| Waukesha Memorial Hospital Regional Cancer Center | |
| Waukesha, Wisconsin, United States, 53188 | |
| Canada, Alberta | |
| Cross Cancer Institute | |
| Edmonton, Alberta, Canada, T6G 1Z2 | |
| Tom Baker Cancer Center - Calgary | |
| Calgary, Alberta, Canada, T2N 4N2 | |
| Canada, New Brunswick | |
| Doctor Leon Richard Oncology Centre | |
| Moncton, New Brunswick, Canada, E1C 8X3 | |
| Saint John Regional Hospital | |
| Saint John, New Brunswick, Canada, E2L 4L2 | |
| Canada, Newfoundland and Labrador | |
| Newfoundland Cancer Treatment and Research Foundation | |
| St. Johns, Newfoundland and Labrador, Canada, A1B 3V6 | |
| Canada, Nova Scotia | |
| Nova Scotia Cancer Centre | |
| Halifax, Nova Scotia, Canada, B3H 1V7 | |
| Canada, Ontario | |
| Cancer Care Ontario-London Regional Cancer Centre | |
| London, Ontario, Canada, N6A 4L6 | |
| Northwestern Ontario Regional Cancer Care | |
| Thunder Bay, Ontario, Canada, P7B 6V4 | |
| Margaret and Charles Juravinski Cancer Centre | |
| Hamilton, Ontario, Canada, L8V 5C2 | |
| Northeastern Ontario Regional Cancer Centre at Regional Hospital of Sudbury Regional Hospital | |
| Sudbury, Ontario, Canada, P3E 5J1 | |
| Kingston Regional Cancer Centre | |
| Kingston, Ontario, Canada, K7L 5P9 | |
| Ottawa Regional Cancer Centre | |
| Ottawa, Ontario, Canada, K1H 1C4 | |
| Princess Margaret Hospital | |
| Toronto, Ontario, Canada, M5G 2M9 | |
| Toronto Sunnybrook Regional Cancer Centre | |
| Toronto, Ontario, Canada, M4N 3M5 | |
| Canada, Quebec | |
| Centre Hospitalier de l'Universite de Montreal | |
| Montreal, Quebec, Canada, H2L 4MI | |
| Centre Hospitalier Universitaire de Quebec | |
| Quebec City, Quebec, Canada, G1R 2J6 | |
| CHUS-Hopital Fleurimont | |
| Fleurimont, Quebec, Canada, J1H 5N4 | |
| McGill University | |
| Montreal, Quebec, Canada, H2W 1S6 | |
| Canada, Saskatchewan | |
| Allan Blair Cancer Centre | |
| Regina, Saskatchewan, Canada, S4T 7T1 | |
| Saskatoon Cancer Centre | |
| Saskatoon, Saskatchewan, Canada, S7N 4H4 | |
| Study Chair: | Paul A. Bunn, MD | University of Colorado at Denver and Health Sciences Center |
| Study Chair: | Joseph A. Treat, MD | Fox Chase Cancer Center CCOP Research Base |
| Study Chair: | Randolph S. Marks, MD | Mayo Clinic |
| Study Chair: | Corey J. Langer, MD | Fox Chase Cancer Center |
More Information
| Study ID Numbers: | CDR0000067223, SWOG-S9900, ECOG-S9900, NCCTG-S9900, RTOG-L0015 |
| Study First Received: | November 1, 1999 |
| Last Updated: | February 6, 2009 |
| ClinicalTrials.gov Identifier: | NCT00004011 History of Changes |
| Health Authority: | United States: Federal Government |
|
stage I non-small cell lung cancer stage II non-small cell lung cancer stage IIIA non-small cell lung cancer |
|
Thoracic Neoplasms Respiratory Tract Neoplasms Neoplasms by Histologic Type Molecular Mechanisms of Pharmacological Action Antineoplastic Agents Mitosis Modulators Antimitotic Agents Carboplatin Pharmacologic Actions Carcinoma Neoplasms |
Neoplasms by Site Respiratory Tract Diseases Lung Neoplasms Paclitaxel Therapeutic Uses Lung Diseases Tubulin Modulators Antineoplastic Agents, Phytogenic Carcinoma, Non-Small-Cell Lung Neoplasms, Glandular and Epithelial |
