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| Sponsor: | Radiation Therapy Oncology Group |
|---|---|
| Collaborator: |
National Cancer Institute (NCI) |
| Information provided by: | National Cancer Institute (NCI) |
| ClinicalTrials.gov Identifier: | NCT00002602 |
Purpose
RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells and may be an effective treatment for prostate cancer.
PURPOSE: Phase I/II trial to study the effectiveness of radiation therapy in treating patients who have previously untreated stage II or stage III prostate cancer.
| Condition | Intervention | Phase |
|---|---|---|
|
Prostate Cancer |
Radiation: radiation therapy |
Phase I Phase II |
| Study Type: | Interventional |
| Study Design: | Treatment |
| Official Title: | A PHASE I/II DOSE ESCALATION STUDY USING THREE DIMENSIONAL CONFORMAL RADIATION THERAPY FOR ADENOCARCINOMA OF THE PROSTATE |
| Estimated Enrollment: | 801 |
| Study Start Date: | May 1994 |
OBJECTIVES: I. Determine the maximum tolerated dose of 3-dimensional conformal radiotherapy to the prostate gland and immediately surrounding tissues in patients with stage II or III adenocarcinoma of the prostate. II. Determine the normal tissue toxicity rate of this regimen in the rectums and bladders of these patients. III. Determine local control by clinical and pathologic examination and by PSA determinations in patients treated with this regimen. IV. Determine the distant failure and overall survival of patients treated with this regimen.
OUTLINE: This is a dose escalation study. Patients are stratified according to 1 of the following 3 prognostic groups: Group 1: T1b-c or T2a-b with combined PSA/Gleason (CPG) score 15 and under Group 2: T1b-c or T2a-b with CPG score more than 15, or any T2c with PSA less than 70 ng/mL Group 3: T3 with PSA less than 70 ng/mL Patients receive 3-dimensional (3-D) conformal radiotherapy 5 days a week for 7.6, 8.2, or 8.8 weeks. Cohorts of 120-270 patients receive escalating doses of 3-D conformal radiotherapy until the maximum tolerated dose (MTD) is determined. The MTD is defined as the dose preceding that at which 20% of patients experience dose-limiting toxicity. Patients are followed every 3 months for 1 year, every 4 months for 1 year, every 6 months for 3 years, and then annually thereafter.
PROJECTED ACCRUAL: A total of 549-801 patients (120-204 patients for the first dose level, 237-321 patients for the second dose level, and 192-276 patients for the third dose level) will be accrued for this study within 4.75 to 5.25 years.
Eligibility| Ages Eligible for Study: | 18 Years and older |
| Genders Eligible for Study: | Male |
| Accepts Healthy Volunteers: | No |
DISEASE CHARACTERISTICS: Previously untreated adenocarcinoma of the prostate T1b-c or T2a-b with a Gleason score more than 5 and PSA greater than 4 ng/mL OR Any T3 PSA under 70 ng/mL within 3 weeks prior to entry and at least 10 days after prostate biopsy No biopsy proven regional nodal involvement No distant metastases
PATIENT CHARACTERISTICS: Age: 18 and over Performance status: Karnofsky 80-100% Hematopoietic: WBC at least 4,000/mm3 Platelet count at least 100,000/mm3 Hemoglobin at least 11 g/dL Hepatic: Not specified Renal: Not specified Other: No major medical or psychiatric illness that would preclude study No other malignancy within the past 5 years
PRIOR CONCURRENT THERAPY: Biologic therapy: Not specified Chemotherapy: No prior or concurrent chemotherapy Endocrine therapy: Prior hormonal therapy allowed Radiotherapy: No prior pelvic irradiation Surgery: No prior prostatectomy or cryosurgery for prostate cancer
Contacts and Locations
Hide Study Locations| United States, Alabama | |
| Alabama Oncology, LLC | |
| Montgomery, Alabama, United States, 36106-2801 | |
| Comprehensive Cancer Institute of Huntsville | |
| Huntsville, Alabama, United States, 35801 | |
| MBCCOP - University of South Alabama | |
| Mobile, Alabama, United States, 36688 | |
| Mobile Infirmary Medical Center | |
| Mobile, Alabama, United States, 36640-0460 | |
| Radiation Oncology Associates of West Alabama | |
| Tuscaloosa, Alabama, United States, 35401 | |
| University of Alabama Comprehensive Cancer Center | |
| Birmingham, Alabama, United States, 35294 | |
| United States, Alaska | |
| Providence Cancer Therapy Center | |
| Anchorage, Alaska, United States, 99508 | |
| United States, Arizona | |
| Arizona Cancer Center | |
| Tucson, Arizona, United States, 85724 | |
| United States, California | |
| Beckman Research Institute, City of Hope | |
| Los Angeles, California, United States, 91010 | |
| California Cancer Center | |
| Fresno, California, United States, 93720 | |
| Cancer Care Center | |
| Pomona, California, United States, 91767 | |
| Glendale Memorial Hospital and Health Center | |
| Glendale, California, United States, 91204 | |
| CCOP - Santa Rosa Memorial Hospital | |
| Santa Rosa, California, United States, 95403 | |
| CCOP - Bay Area Tumor Institute | |
| Oakland, California, United States, 94609-3305 | |
| Jonsson Comprehensive Cancer Center, UCLA | |
| Los Angeles, California, United States, 90095-1781 | |
| Kaiser Permanente Medical Center - Los Angeles | |
| Los Angeles, California, United States, 90027 | |
| Loma Linda University Medical Center | |
| Loma Linda, California, United States, 92354 | |
| Mount Diablo Medical Center | |
| Concord, California, United States, 94524-4110 | |
| Saint Agnes Cancer Center | |
| Fresno, California, United States, 93720 | |
| Radiation Oncology Center - Sacramento | |
| Sacramento, California, United States, 95816 | |
| O'Connor Hospital | |
| San Jose, California, United States, 95128 | |
| Stanford University | |
| Stanford, California, United States, 94305 | |
| Sutter Health Western Division Cancer Research Group | |
| Greenbrae, California, United States, 94904 | |
| UCSF Cancer Center and Cancer Research Institute | |
| San Francisco, California, United States, 94115-0128 | |
| USC/Norris Comprehensive Cancer Center | |
| Los Angeles, California, United States, 90033-0800 | |
| Veterans Affairs Medical Center - Long Beach | |
| Long Beach, California, United States, 90822 | |
| United States, Colorado | |
| Memorial Hospital Cancer Center | |
| Colorado Springs, Colorado, United States, 80909 | |
| University of Colorado Cancer Center | |
| Denver, Colorado, United States, 80262 | |
| United States, Connecticut | |
| Bridgeport Hospital | |
| Bridgeport, Connecticut, United States, 06610 | |
| Whittingham Cancer Center | |
| Norwalk, Connecticut, United States, 06856 | |
| United States, Delaware | |
| CCOP - Christiana Care Health Services | |
| Wilmington, Delaware, United States, 19899 | |
| United States, District of Columbia | |
| Walter Reed Army Medical Center | |
| Washington, District of Columbia, United States, 20307-5000 | |
| United States, Florida | |
| Baptist Hospital of Miami | |
| Miami, Florida, United States, 33176-2197 | |
| Bayfront Medical Center | |
| Saint Petersburg, Florida, United States, 33701 | |
| CCOP - Mount Sinai Medical Center | |
| Miami Beach, Florida, United States, 33140 | |
| Florida Radiation Oncology Group | |
| Orange Park, Florida, United States, 32073 | |
| Sarasota Radiation and Medical Oncology Center | |
| Sarasota, Florida, United States, 34233 | |
| H. Lee Moffitt Cancer Center and Research Institute | |
| Tampa, Florida, United States, 33612 | |
| Halifax Medical Center | |
| Daytona Beach, Florida, United States, 32114 | |
| Health First Holmes Regional Medical Center | |
| Melbourne, Florida, United States, 32901 | |
| MD Anderson Cancer Center Orlando | |
| Orlando, Florida, United States, 32806 | |
| Radiation Therapy Associates - Fort Myers | |
| Fort Myers, Florida, United States, 33901 | |
| Gulf Coast Cancer Treatment Center | |
| Panama City, Florida, United States, 32405-4587 | |
| Sylvester Cancer Center, University of Miami | |
| Miami, Florida, United States, 33136 | |
| University of Florida Health Science Center | |
| Gainesville, Florida, United States, 32610-0296 | |
| West Florida Cancer Institute - Pensacola | |
| Pensacola, Florida, United States, 32514 | |
| United States, Georgia | |
| CCOP - Atlanta Regional | |
| Atlanta, Georgia, United States, 30342-1701 | |
| Medical Center/John B. Amos Community Cancer Center | |
| Columbus, Georgia, United States, 31902 | |
| InterCommunity Cancer Center at Rome | |
| Rome, Georgia, United States, 30161 | |
| Emory University Hospital - Atlanta | |
| Atlanta, Georgia, United States, 30322 | |
| United States, Illinois | |
| Northwestern Memorial Hospital | |
| Chicago, Illinois, United States, 60611 | |
| Ingalls Memorial Hospital | |
| Harvey, Illinois, United States, 60426 | |
| Loyola University Medical Center | |
| Maywood, Illinois, United States, 60153 | |
| Lutheran General Cancer Care Center | |
| Park Ridge, Illinois, United States, 60068 | |
| Methodist Medical Center of Illinois | |
| Peoria, Illinois, United States, 61636 | |
| Northwest Community Hospital | |
| Arlington Heights, Illinois, United States, 60005 | |
| CCOP - Central Illinois | |
| Decatur, Illinois, United States, 62526 | |
| University of Chicago Cancer Research Center | |
| Chicago, Illinois, United States, 60637 | |
| United States, Indiana | |
| Ball Memorial Hospital | |
| Muncie, Indiana, United States, 47303-3499 | |
| Clarion Health Partners Inc. | |
| Indianapolis, Indiana, United States, 46206-1367 | |
| Community Hospitals of Indianapolis - Regional Cancer Center | |
| Indianapolis, Indiana, United States, 46219 | |
| Memorial Hospital of South Bend | |
| South Bend, Indiana, United States, 46601 | |
| St. John's Medical Center | |
| Anderson, Indiana, United States, 46016 | |
| St. Joseph's Radiation Oncology Center | |
| South Bend, Indiana, United States, 46617 | |
| United States, Iowa | |
| University of Iowa Hospitals and Clinics | |
| Iowa City, Iowa, United States, 52242 | |
| Wendt Regional Cancer Center of Finley Hospital | |
| Dubuque, Iowa, United States, 52001 | |
| United States, Kentucky | |
| Albert B. Chandler Medical Center, University of Kentucky | |
| Lexington, Kentucky, United States, 40536-0084 | |
| James Graham Brown Cancer Center | |
| Louisville, Kentucky, United States, 40202 | |
| Louisville Radiation Oncology | |
| Louisville, Kentucky, United States, 40215 | |
| Western Baptist Hospital | |
| Paducah, Kentucky, United States, 42001 | |
| Veterans Affairs Medical Center - Lexington | |
| Lexington, Kentucky, United States, 40511-1093 | |
| Merle M. Mahr Cancer Center | |
| Madisonville, Kentucky, United States, 42431 | |
| United States, Louisiana | |
| CCOP - Ochsner | |
| New Orleans, Louisiana, United States, 70121 | |
| Mary Bird Perkins Cancer Center | |
| Baton Rouge, Louisiana, United States, 70809 | |
| MBCCOP - LSU Medical Center | |
| New Orleans, Louisiana, United States, 70112 | |
| Romagosa Radiation Oncology Center | |
| Lafayette, Louisiana, United States, 70501 | |
| Tulane University School of Medicine | |
| New Orleans, Louisiana, United States, 70112 | |
| United States, Maine | |
| Maine Medical Center | |
| Portland, Maine, United States, 04102 | |
| United States, Maryland | |
| Anne Arundel Oncology Center | |
| Annapolis, Maryland, United States, 21401 | |
| Greater Baltimore Medical Center and Cancer Center | |
| Baltimore, Maryland, United States, 21204 | |
| Harbor Hospital Center | |
| Baltimore, Maryland, United States, 21225 | |
| Johns Hopkins Oncology Center | |
| Baltimore, Maryland, United States, 21231 | |
| Radiation Oncology Affiliates of Maryland, P.A. | |
| Baltimore, Maryland, United States, 21237 | |
| United States, Massachusetts | |
| Cape Cod Hospital | |
| Hyannis, Massachusetts, United States, 02601 | |
| Veterans Affairs Medical Center - Boston (Jamaica Plain) | |
| Jamaica Plain, Massachusetts, United States, 02130 | |
| United States, Michigan | |
| Barbara Ann Karmanos Cancer Institute | |
| Detroit, Michigan, United States, 48201 | |
| CCOP - Ann Arbor Regional | |
| Ann Arbor, Michigan, United States, 48106 | |
| CCOP - Kalamazoo | |
| Kalamazoo, Michigan, United States, 49007-3731 | |
| Henry Ford Hospital | |
| Detroit, Michigan, United States, 48202 | |
| Hurley Medical Center | |
| Flint, Michigan, United States, 48503 | |
| MidMichigan Regional Medical Center | |
| Midland, Michigan, United States, 48670 | |
| McLaren Regional Cancer Center | |
| Flint, Michigan, United States, 48432 | |
| Marquette General Hospital | |
| Marquette, Michigan, United States, 49855 | |
| St. Mary's Medical Center | |
| Saginaw, Michigan, United States, 48601 | |
| University of Michigan Comprehensive Cancer Center | |
| Ann Arbor, Michigan, United States, 48109-0752 | |
| United States, Minnesota | |
| CCOP - Metro-Minnesota | |
| Saint Louis Park, Minnesota, United States, 55416 | |
| Mayo Clinic Cancer Center | |
| Rochester, Minnesota, United States, 55905 | |
| United States, Missouri | |
| CCOP - Kansas City | |
| Kansas City, Missouri, United States, 64131 | |
| CCOP - Cancer Research for the Ozarks | |
| Springfield, Missouri, United States, 65807 | |
| Cancer Research for the Ozarks | |
| Springfield, Missouri, United States, 65807 | |
| Ellis Fischel Cancer Center - Columbia | |
| Columbia, Missouri, United States, 65203 | |
| Mallinckrodt Institute of Radiology | |
| Saint Louis, Missouri, United States, 63110 | |
| St. Louis University Health Sciences Center | |
| Saint Louis, Missouri, United States, 63110-0250 | |
| United States, Montana | |
| CCOP - Montana Cancer Consortium | |
| Billings, Montana, United States, 59101 | |
| United States, Nebraska | |
| Methodist Cancer Center - Omaha | |
| Omaha, Nebraska, United States, 68114 | |
| United States, Nevada | |
| CCOP - Southern Nevada Cancer Research Foundation | |
| Las Vegas, Nevada, United States, 89106 | |
| United States, New Hampshire | |
| Elliot Regional Cancer Center | |
| Manchester, New Hampshire, United States, 03103 | |
| Norris Cotton Cancer Center | |
| Lebanon, New Hampshire, United States, 03756 | |
| United States, New Jersey | |
| Community Medical Center | |
| Toms River, New Jersey, United States, 08755 | |
| Fox Chase Cancer Center at Virtua-Memorial Hospital Burlington County | |
| Mount Holly, New Jersey, United States, 08060 | |
| John F. Kennedy Medical Center | |
| Edison, New Jersey, United States, 08818 | |
| St. Francis Medical Center | |
| Trenton, New Jersey, United States, 08629 | |
| South Jersey Hospital - Millville | |
| Millville, New Jersey, United States, 08332 | |
| Newark Beth Israel Medical Center | |
| Newark, New Jersey, United States, 07112 | |
| Trinitas Hospital - Jersey Street Campus | |
| Elizabeth, New Jersey, United States, 07201 | |
| Veterans Affairs Medical Center - East Orange | |
| East Orange, New Jersey, United States, 07018-1095 | |
| United States, New Mexico | |
| Saint Joseph Medical Center | |
| Albuquerque, New Mexico, United States, 87102 | |
| United States, New York | |
| Albert Einstein Comprehensive Cancer Center | |
| Bronx, New York, United States, 10461 | |
| Beth Israel Medical Center | |
| New York, New York, United States, 10003 | |
| Cancer Center of Albany Medical Center | |
| Albany, New York, United States, 12208 | |
| CCOP - North Shore University Hospital | |
| Manhasset, New York, United States, 11030 | |
| Champlain Valley Physicians Hospital Medical Center | |
| Plattsburgh, New York, United States, 12901 | |
| State University of New York Health Science Center at Brooklyn | |
| Brooklyn, New York, United States, 11203 | |
| Kaplan Cancer Center | |
| New York, New York, United States, 10016 | |
| Memorial Sloan-Kettering Cancer Center | |
| New York, New York, United States, 10021 | |
| New York Medical College | |
| Valhalla, New York, United States, 10595 | |
| New York Methodist Hospital | |
| Brooklyn, New York, United States, 11215-3609 | |
| Roswell Park Cancer Institute | |
| Buffalo, New York, United States, 14263-0001 | |
| Finger Lakes Radiation Oncology, P.C. | |
| Clifton Springs, New York, United States, 14432 | |
| University of Rochester Cancer Center | |
| Rochester, New York, United States, 14642 | |
| Vassar Brothers Hospital | |
| Poughkeepsie, New York, United States, 12601 | |
| United States, North Carolina | |
| Catawba Memorial Hospital | |
| Hickory, North Carolina, United States, 28601 | |
| CCOP - Southeast Cancer Control Consortium | |
| Winston-Salem, North Carolina, United States, 27104-4241 | |
| Lineberger Comprehensive Cancer Center, UNC | |
| Chapel Hill, North Carolina, United States, 27599-7295 | |
| East Carolina University School of Medicine | |
| Greenville, North Carolina, United States, 27858-4354 | |
| Comprehensive Cancer Center of Wake Forest University Baptist Medical Center | |
| Winston-Salem, North Carolina, United States, 27157-1082 | |
| Northeast Medical Center | |
| Concord, North Carolina, United States, 28025 | |
| United States, North Dakota | |
| Meritcare Roger Maris Cancer Center | |
| Fargo, North Dakota, United States, 58122 | |
| UNIMED Medical Center | |
| Minot, North Dakota, United States, 58701 | |
| United States, Ohio | |
| Akron City Hospital | |
| Akron, Ohio, United States, 44309 | |
| CCOP - Columbus | |
| Columbus, Ohio, United States, 43206 | |
| Arthur G. James Cancer Hospital - Ohio State University | |
| Columbus, Ohio, United States, 43210 | |
| Akron General Medical Center | |
| Akron, Ohio, United States, 44302 | |
| CCOP - Dayton | |
| Kettering, Ohio, United States, 45429 | |
| CCOP - Toledo Community Hospital Oncology Program | |
| Toledo, Ohio, United States, 43623-3456 | |
| Christ Hospital | |
| Cincinnati, Ohio, United States, 45219 | |
| Cleveland Clinic Cancer Center | |
| Cleveland, Ohio, United States, 44195 | |
| Ireland Cancer Center | |
| Cleveland, Ohio, United States, 44106-5065 | |
| University Hospitals of Cleveland | |
| Cleveland, Ohio, United States, 44106 | |
| United States, Oklahoma | |
| St. John Medical Center | |
| Tulsa, Oklahoma, United States, 74104 | |
| United States, Oregon | |
| CCOP - Columbia River Program | |
| Portland, Oregon, United States, 97213 | |
| United States, Pennsylvania | |
| Albert Einstein Cancer Center | |
| Philadelphia, Pennsylvania, United States, 19141 | |
| CCOP - MainLine Health | |
| Wynnewood, Pennsylvania, United States, 19096 | |
| Delaware County Memorial Hospital | |
| Drexel Hill, Pennsylvania, United States, 19026 | |
| Kimmel Cancer Center of Thomas Jefferson University - Philadelphia | |
| Philadelphia, Pennsylvania, United States, 19107 | |
| Hahnemann University Hospital | |
| Philadelphia, Pennsylvania, United States, 19102-1192 | |
| Fox Chase Cancer Center | |
| Philadelphia, Pennsylvania, United States, 19111 | |
| Lehigh Valley Hospital | |
| Allentown, Pennsylvania, United States, 18103 | |
| Mercy Catholic Medical Center, Mercy Fitzgerald Divison | |
| Darby, Pennsylvania, United States, 19023 | |
| Mercy Hospital Cancer Center - Scranton | |
| Scranton, Pennsylvania, United States, 18501 | |
| Mercy Hospital of Pittsburgh | |
| Pittsburgh, Pennsylvania, United States, 15219 | |
| Reading Hospital and Medical Center | |
| Reading, Pennsylvania, United States, 19612-6052 | |
| Penn State Geisinger Medical Center | |
| Danville, Pennsylvania, United States, 17822-2001 | |
| Penn State Geisinger Cancer Center | |
| Hershey, Pennsylvania, United States, 17033 | |
| University of Pennsylvania Cancer Center | |
| Philadelphia, Pennsylvania, United States, 19104 | |
| University of Pittsburgh Cancer Institute | |
| Pittsburgh, Pennsylvania, United States, 15213 | |
| Veterans Affairs Medical Center - Philadelphia | |
| Philadelphia, Pennsylvania, United States, 19104 | |
| Western Pennsylvania Hospital | |
| Pittsburgh, Pennsylvania, United States, 15224 | |
| Wilkes Barre General Hospital | |
| Wilkes-Barre, Pennsylvania, United States, 18764 | |
| York Hospital | |
| York, Pennsylvania, United States, 17315 | |
| United States, Rhode Island | |
| Roger Williams Medical Center/BUSM | |
| Providence, Rhode Island, United States, 02908-4735 | |
| United States, South Carolina | |
| CCOP - Greenville | |
| Greenville, South Carolina, United States, 29615 | |
| CCOP - Upstate Carolina | |
| Spartanburg, South Carolina, United States, 29303 | |
| Medical University of South Carolina | |
| Charleston, South Carolina, United States, 29425-0721 | |
| United States, Tennessee | |
| Baptist Regional Cancer Center - Knoxville | |
| Knoxville, Tennessee, United States, 37901 | |
| Vanderbilt Cancer Center | |
| Nashville, Tennessee, United States, 37232-6838 | |
| Jackson-Madison County General Hospital | |
| Jackson, Tennessee, United States, 38301 | |
| University of Tennessee, Memphis Cancer Center | |
| Memphis, Tennessee, United States, 38163 | |
| CCOP - Baptist Cancer Institute | |
| Memphis, Tennessee, United States, 38117 | |
| United States, Texas | |
| Wilford Hall - 59th Medical Wing | |
| Lackland Air Force Base, Texas, United States, 78236-5300 | |
| East Texas Medical Center - Cancer Institute | |
| Tyler, Texas, United States, 75701 | |
| Harrington Cancer Center | |
| Amarillo, Texas, United States, 79106 | |
| Joe Arrington Cancer Research and Treatment Center | |
| Lubbock, Texas, United States, 79410-1894 | |
| Julie and Ben Rogers Cancer Institute | |
| Beaumont, Texas, United States, 77701 | |
| University of Texas Medical Branch | |
| Galveston, Texas, United States, 77555-1329 | |
| Bayshore Medical Center | |
| Pasadena, Texas, United States, 77504 | |
| United States, Utah | |
| Dixie Regional Medical Center | |
| Saint George, Utah, United States, 84770 | |
| LDS Hospital | |
| Salt Lake City, Utah, United States, 84143 | |
| United States, Vermont | |
| CCOP - Southwestern Vermont Regional Cancer Center | |
| Bennington, Vermont, United States, 05201 | |
| Green Mountain Oncology Group | |
| Rutland, Vermont, United States, 05701 | |
| Vermont Cancer Center | |
| Burlington, Vermont, United States, 05401-3498 | |
| United States, Virginia | |
| Cancer Center, University of Virginia HSC | |
| Charlottesville, Virginia, United States, 22908 | |
| Martha Jefferson Hospital | |
| Charlottesville, Virginia, United States, 22901 | |
| Naval Medical Center, Portsmouth | |
| Portsmouth, Virginia, United States, 23708-2197 | |
| Virginia Baptist Hospital | |
| Lynchburg, Virginia, United States, 24503 | |
| United States, Washington | |
| Deaconess Medical Center | |
| Spokane, Washington, United States, 99210-0248 | |
| Swedish Cancer Institute | |
| Seattle, Washington, United States, 98104 | |
| Virginia Mason Medical Center | |
| Seattle, Washington, United States, 98111 | |
| Yakima Valley Memorial Hospital | |
| Yakima, Washington, United States, 98902 | |
| United States, West Virginia | |
| Schiffler Cancer Center | |
| Wheeling, West Virginia, United States, 26003 | |
| United States, Wisconsin | |
| Columbia Hospital | |
| Milwaukee, Wisconsin, United States, 53211 | |
| Community Memorial Hospital | |
| Menomonee Falls, Wisconsin, United States, 53051 | |
| Gundersen Lutheran Medical Foundation | |
| La Crosse, Wisconsin, United States, 54601 | |
| Marshfield Clinic | |
| Marshfield, Wisconsin, United States, 54449 | |
| Southern Wisconsin Radiotherapy Center | |
| Madison, Wisconsin, United States, 53713 | |
| Southeastern Wisconsin Regional Cancer Center | |
| Racine, Wisconsin, United States, 53405 | |
| Medical College of Wisconsin | |
| Milwaukee, Wisconsin, United States, 53226 | |
| St. Joseph's Hospital | |
| Milwaukee, Wisconsin, United States, 53210 | |
| St. Luke's Medical Center | |
| Milwaukee, Wisconsin, United States, 53215 | |
| St. Vincent Hospital | |
| Green Bay, Wisconsin, United States, 54307-3508 | |
| University of Wisconsin Comprehensive Cancer Center | |
| Madison, Wisconsin, United States, 53792 | |
| Veterans Affairs Medical Center - Milwaukee (Zablocki) | |
| Milwaukee, Wisconsin, United States, 53295 | |
| Waukesha Memorial Hospital | |
| Waukesha, Wisconsin, United States, 53188 | |
| Canada, Alberta | |
| Cross Cancer Institute | |
| Edmonton, Alberta, Canada, T6G 1Z2 | |
| Tom Baker Cancer Center - Calgary | |
| Calgary, Alberta, Canada, T2N 4N2 | |
| Canada, New Brunswick | |
| Doctor Leon Richard Oncology Centre | |
| Moncton, New Brunswick, Canada, E1C 8X3 | |
| Saint John Regional Hospital | |
| Saint John, New Brunswick, Canada, E2L 4L2 | |
| Canada, Nova Scotia | |
| Nova Scotia Cancer Centre | |
| Halifax, Nova Scotia, Canada, B3H 1V7 | |
| Canada, Ontario | |
| Kingston Regional Cancer Centre | |
| Kingston, Ontario, Canada, K7L 5P9 | |
| Cancer Care Ontario-London Regional Cancer Centre | |
| London, Ontario, Canada, N6A 4L6 | |
| Cancer Care Ontario-Hamilton Regional Cancer Centre | |
| Hamilton, Ontario, Canada, L8V 5C2 | |
| Northeastern Ontario Regional Cancer Centre, Sudbury | |
| Sudbury, Ontario, Canada, P3E 5J1 | |
| Northwestern Ontario Regional Cancer Centre, Thunder Bay | |
| Thunder Bay, Ontario, Canada, P7A 7T1 | |
| Ottawa Regional Cancer Centre - Civic Campus | |
| Ottawa, Ontario, Canada, K1Y 4K7 | |
| Princess Margaret Hospital | |
| Toronto, Ontario, Canada, M5G 2M9 | |
| Toronto Sunnybrook Regional Cancer Centre | |
| Toronto, Ontario, Canada, M4N 3M5 | |
| Canada, Quebec | |
| McGill University Department of Oncology | |
| Montreal, Quebec, Canada, H2W 1S6 | |
| Canada, Saskatchewan | |
| Saskatoon Cancer Centre | |
| Saskatoon, Saskatchewan, Canada, S7N 4H4 | |
| Study Chair: | James D. Cox, MD | M.D. Anderson Cancer Center |
More Information
| Study ID Numbers: | CDR0000063854, RTOG-3D/OG-9406 |
| Study First Received: | November 1, 1999 |
| Last Updated: | July 11, 2009 |
| ClinicalTrials.gov Identifier: | NCT00002602 History of Changes |
| Health Authority: | United States: Federal Government |
|
adenocarcinoma of the prostate stage II prostate cancer stage III prostate cancer |
|
Neoplasms Neoplasms by Site Prostatic Diseases Genital Neoplasms, Male |
Urogenital Neoplasms Genital Diseases, Male Prostatic Neoplasms |
