Effects of Alcohol History on Effects of Nitrous Oxide - 9

This study has been completed.

First Received: September 20, 1999 Last Updated: August 16, 2005 History of Changes

Sponsor:	National Institute on Drug Abuse (NIDA)
Collaborator:	University of Chicago
Information provided by:	National Institute on Drug Abuse (NIDA)
ClinicalTrials.gov Identifier:	NCT00000257

Purpose

The purpose of this study is to conduct experiments to examine subjective and reinforcing effects of nitrous oxide. Mood altering and psychomotor effects will be tested on non-drug abusers and preference procedures will be used to assess reinforcing effects. Comparisons between nitrous oxide, opiates, and benzodiazepine antagonists will be made. To determine effects of alcohol history on the reinforcing, subjective and psychomotor effects of nitrous oxide in healthy volunteers.

Condition	Intervention	Phase
Alcohol-Related Disorders Opioid-Related Disorders Substance-Related Disorders	Drug: Nitrous oxide	Phase II

Study Type:	Interventional
Study Design:	Treatment
Official Title:	Effects of Alcohol History on Effects of Nitrous Oxide

Resource links provided by NLM:

Drug Information available for: Nitrous oxide

U.S. FDA Resources

Further study details as provided by National Institute on Drug Abuse (NIDA):

Primary Outcome Measures:

Mood
Psychomotor performance
Choice of nitrous oxide vs placebo

Estimated Enrollment:	0
Study Start Date:	September 1995

Eligibility

Ages Eligible for Study:	21 Years to 37 Years
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No

Criteria

Please contact site for information.

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00000257

Locations

United States, Illinois
University of Chicago, Anesthesia & Critical Care
Chicago, Illinois, United States, 60637

Sponsors and Collaborators

National Institute on Drug Abuse (NIDA)

University of Chicago

Investigators

Principal Investigator:

James Zacny, Ph.D.

University of Chicago

More Information

No publications provided

Study ID Numbers:	NIDA-08391-9, R01-08391-9
Study First Received:	September 20, 1999
Last Updated:	August 16, 2005
ClinicalTrials.gov Identifier:	NCT00000257 History of Changes
Health Authority:	United States: Federal Government

Additional relevant MeSH terms:

Disease
Nitrous Oxide
Physiological Effects of Drugs
Central Nervous System Depressants
Anesthetics
Disorders of Environmental Origin
Opioid-Related Disorders
Pharmacologic Actions
Anesthetics, Inhalation
Pathologic Processes

Anesthetics, General
Mental Disorders
Analgesics, Non-Narcotic
Sensory System Agents
Therapeutic Uses
Substance-Related Disorders
Alcohol-Related Disorders
Analgesics
Peripheral Nervous System Agents
Central Nervous System Agents

ClinicalTrials.gov processed this record on November 27, 2009