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Benidipine-based Comparison of Angiotensin Receptors, β-blockers, or Thiazide Diuretics in Hypertensive Patients (COPE)

This study has been completed.

Sponsor:

Collaborators:

The Japanese Society of Hypertension

Yamaguchi University Hospital

Kyowa Hakko Kogyo Co., Ltd.

Information provided by (Responsible Party):

Seiji Umemoto, M.D., Ph.D., COPE Trial Group

ClinicalTrials.gov Identifier:

NCT00135551

First received: August 24, 2005

Last updated: February 19, 2012

Last verified: February 2012

History of Changes

No Study Results Posted on ClinicalTrials.gov for this Study

About Study Results Reporting on ClinicalTrials.gov

Study Status:	This study has been completed.
Study Completion Date:	November 2010
Primary Completion Date:	May 2010 (Final data collection date for primary outcome measure)

Publications:

Matsuzaki M, Ogihara T, Umemoto S, Rakugi H, Matsuoka H, Shimada K, Abe K, Suzuki N, Eto T, Higaki J, Ito S, Kamiya A, Kikuchi K, Suzuki H, Tei C, Ohashi Y, Saruta T; Combination Therapy of Hypertension to Prevent Cardiovascular Events Trial Group. Prevention of cardiovascular events with calcium channel blocker-based combination therapies in patients with hypertension: a randomized controlled trial. J Hypertens. 2011 Aug;29(8):1649-59.

Ogihara T, Matsuzaki M, Umemoto S, Rakugi H, Matsuoka H, Shimada K, Higaki J, Ito S, Kamiya A, Suzuki H, Ohashi Y, Shimamoto K, Saruta T. Combination therapy for hypertension in the elderly: a sub-analysis of the Combination Therapy of Hypertension to Prevent Cardiovascular Events (COPE) Trial. Hypertens Res. 2012 Jan 26. doi: 10.1038/hr.2011.216. [Epub ahead of print]