The Role of Primary Motor Cortex and Prefrontal Cortex for Facilitation of Motor System and Working Memory

This study is currently recruiting participants. (see Contacts and Locations)
Verified December 2013 by Taipei Veterans General Hospital, Taiwan
Sponsor:
Information provided by (Responsible Party):
vghtpe user, Taipei Veterans General Hospital, Taiwan
ClinicalTrials.gov Identifier:
NCT02006615
First received: December 5, 2013
Last updated: NA
Last verified: December 2013
History: No changes posted

December 5, 2013
December 5, 2013
July 2013
July 2015   (final data collection date for primary outcome measure)
Repeatable Battery for the Assessment of Neuropsychological Status [ Time Frame: up to 3 months ] [ Designated as safety issue: No ]
Same as current
No Changes Posted
Reaction time [ Time Frame: up to 3 months ] [ Designated as safety issue: No ]
Same as current
Not Provided
Not Provided
 
The Role of Primary Motor Cortex and Prefrontal Cortex for Facilitation of Motor System and Working Memory
The Role of Primary Motor Cortex and Prefrontal Cortex for Facilitation of Motor System and Working Memory in Stroke, Parkinson, and Elderly Patients

We hypothesize that ten sessions of repetitive transcranial magnetic stimulation yield ability to upregulate the function of primary motor cortex and prefrontal cortex that play key roles in motor and frontal memory processing.

Excitatory (>3Hz) rTMS could facilitate the brain cortex and neuroplasticity that benefits motor control and working memory when the coil is applied over primary motor cortex or dorsolateral prefrontal gyrus.

Interventional
Not Provided
Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Double Blind (Subject, Outcomes Assessor)
Primary Purpose: Treatment
Central Nervous System Diseases
Device: rTMS
5Hz rTMS over M1 and inferior frontal lobe
Other Name: Magstim rapid2
  • Experimental: 5Hz rTMS
    rTMS group
    Intervention: Device: rTMS
  • Sham Comparator: Sham rTMS
    Sham stimulation
    Intervention: Device: rTMS
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Recruiting
150
July 2015
July 2015   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • Ischemic or hemorrhagic cerebrovascular lesion, Parkinsonism disease, elderly people

Exclusion Criteria:

  • Seizure, metalic implantation, other contra-indications for TMS; Dementia or severe cognitive impairment
Both
30 Years to 80 Years
No
Contact: Po-Yi Tsai, MD 886-228757293 vivitsai0518@gmail.com
Contact: Chih-Jou Lai, MD 886-228757361 milly1204@gmail.com
Taiwan
 
NCT02006615
2013-07-011A
Yes
vghtpe user, Taipei Veterans General Hospital, Taiwan
Taipei Veterans General Hospital, Taiwan
Not Provided
Principal Investigator: Po-Yi Tsai, MD Taipei Veterans General Hospital, Taiwan
Taipei Veterans General Hospital, Taiwan
December 2013

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP