Remifentanil and Nitroprusside for Controlled Hypotension

This study has been completed.
Sponsor:
Information provided by (Responsible Party):
Hyun Jung Kim, Jeju National University School of Medicine
ClinicalTrials.gov Identifier:
NCT02001298
First received: November 24, 2013
Last updated: December 3, 2013
Last verified: November 2013

November 24, 2013
December 3, 2013
June 2012
July 2013   (final data collection date for primary outcome measure)
Cardiac index [ Time Frame: Cardiac index was continuously measured during controlled hypotension, an average of 90 min ] [ Designated as safety issue: Yes ]
Cardiac index was continuously measured during controlled hypotension using noninvasive cardiac output monitor. The average of cardiac index during controlled hypotension was compared with baseline value.
Same as current
Complete list of historical versions of study NCT02001298 on ClinicalTrials.gov Archive Site
Total peripheral resistance index [ Time Frame: Total peripheral resistance index was continuously measured during controlled hypotension, an average of 90 min ] [ Designated as safety issue: Yes ]
Total peripheral resistance index was continuously measured during controlled hypotension using noninvasive cardiac output monitor. The average of total peripheral resistance index during controlled hypotension was compared with baseline value.
Same as current
Stroke volume index [ Time Frame: Stroke volume index was continuously measured during controlled hypotension, an average of 90 min ] [ Designated as safety issue: Yes ]
Stroke volume index was continuously measured during controlled hypotension using noninvasive cardiac output monitor. The average of stroke volume index during controlled hypotension was compared with baseline value.
Same as current
 
Remifentanil and Nitroprusside for Controlled Hypotension
The Comparison of the Cardiovascular Effects of Remifentanil and Nitroprusside for Controlled Hypotension

The purpose of this study is the comparison of the cardiovascular effects of remifentanil and nitroprusside for controlled hypotension

Not Provided
Interventional
Not Provided
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Open Label
Hypotension, Controlled
  • Drug: remifentanil
  • Drug: nitroprusside
  • Experimental: nitroprusside
    After induction of anesthesia, controlled hypotension was induced with continuous infusion of nitroprusside. Cardiac index, stroke volume index, and total peripheral resistance index were continuously measured using noninvasive cardiac output monitor (Cheetah NICOM, Cheetah Medical Inc, UK).
    Intervention: Drug: nitroprusside
  • Experimental: remifentanil
    After induction of anesthesia, controlled hypotension was induced with continuous infusion of remifentanil. Cardiac index, stroke volume index, and total peripheral resistance index were continuously measured using noninvasive cardiac output monitor (Cheetah NICOM, Cheetah Medical Inc, UK).
    Intervention: Drug: remifentanil
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
30
Not Provided
July 2013   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • Patients who underwent endoscopic sinus surgery

Exclusion Criteria:

  • patient who took any drug to influence this study
  • patient with cardiovascular disease, renal disease or liver disease
Both
20 Years to 60 Years
No
Contact information is only displayed when the study is recruiting subjects
Korea, Republic of
 
NCT02001298
HJKim3
Not Provided
Hyun Jung Kim, Jeju National University School of Medicine
Jeju National University School of Medicine
Not Provided
Not Provided
Jeju National University School of Medicine
November 2013

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP