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Synchronization to Improve Non-Adherence to Cardiovascular Medications (SyNCMed)

This study is ongoing, but not recruiting participants.
Sponsor:
Collaborator:
CVS Caremark
Information provided by (Responsible Party):
Niteesh K. Choudhry, MD, PhD, Brigham and Women's Hospital
ClinicalTrials.gov Identifier:
NCT01963156
First received: October 10, 2013
Last updated: June 18, 2014
Last verified: June 2014

October 10, 2013
June 18, 2014
November 2013
June 2014   (final data collection date for primary outcome measure)
Medication adherence [ Time Frame: 12 months ] [ Designated as safety issue: No ]
Average adherence to medications for the treatment of cardiovascular disease and diabetes medications as assessed using administrative pharmacy claims
Same as current
Complete list of historical versions of study NCT01963156 on ClinicalTrials.gov Archive Site
Full adherence to medications for the treatment of diabetes or cardiovascular disease [ Time Frame: 12 months ] [ Designated as safety issue: No ]
Percent of subjects achieving full adherence (defined as a Medication Possession Ratio > 80%) to medications for cardiovascular disease and diabetes
Same as current
Rates of de-synchronization [ Time Frame: 12 months ] [ Designated as safety issue: No ]
Rate at which members whose prescriptions have been synchronized elect to discontinue with the synchronization during the study period
Same as current
 
Synchronization to Improve Non-Adherence to Cardiovascular Medications
Synchronization to Improve Non-Adherence to Cardiovascular Medications (SyNCMed)

The aim of this study is to evaluate if synchronizing when patients with diabetes and/or coronary artery disease fill their prescriptions improves long-term adherence to these medications.

Not Provided
Interventional
Not Provided
Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Health Services Research
  • Chronic Disease
  • Cardiovascular Disease
  • Diabetes Mellitus
Behavioral: Prescription synchronization

Each patient's medication that has the greatest quantity of pills on hand after randomization will be defined as the "index "medication and partial supplies will be provided for all other eligible medications in order to synchronize all of a patient's medication. Prescribers will be contacted for a new prescription to ensure all eligible medications are on the same renewal schedule.

Randomization will occur within strata of whether patients are enrolled in the "ReadyFill@Mail" program. Once synchronized, patients who are not enrolled in the ReadyFill@Mail program will initiate their own refills. Patients who are enrolled in the ReadyFill@Mail program will have their refills automatically filled, however patients may disenroll from ReadyFill@Mail at any time, in which case they will initiate their own refills. Patients may disenroll in whole or in part from the program at any point.

  • Experimental: Prescription synchronization
    Intervention: Behavioral: Prescription synchronization
  • No Intervention: Control
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Active, not recruiting
3675
June 2014
June 2014   (final data collection date for primary outcome measure)

We will enroll patients 18 years of age and older who within 6 months of study enrollment have filled ≥ 2 medications intended for long-term use (i.e. maintenance medications) by mail order at CVS Caremark. At least 1 of these 2 medications of must be for the treatment of diabetes or cardiovascular disease. In addition, these medications must be delivered on two or more unique delivery dates, there must be at least one refill remaining for all eligible medications and either all or none of their prescriptions must be enrolled in the ReadyFill@Mail program (see Intervention Description for details).

Both
18 Years and older
No
Contact information is only displayed when the study is recruiting subjects
United States
 
NCT01963156
Pro00008813
Not Provided
Niteesh K. Choudhry, MD, PhD, Brigham and Women's Hospital
Brigham and Women's Hospital
CVS Caremark
Principal Investigator: Niteesh K Choudhry, MD, PhD Brigham and Women's Hospital/Harvard Medical School
Brigham and Women's Hospital
June 2014

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP