Postural Responses to External Perturbation in Post-Stroke

This study is not yet open for participant recruitment. (see Contacts and Locations)
Verified July 2013 by University of Sao Paulo
Sponsor:
Information provided by (Responsible Party):
Alessandra Rezende Martinelli, University of Sao Paulo
ClinicalTrials.gov Identifier:
NCT01912794
First received: July 26, 2013
Last updated: July 30, 2013
Last verified: July 2013

July 26, 2013
July 30, 2013
August 2013
February 2014   (final data collection date for primary outcome measure)
Displacement amplitude of the CP to the anterior-posterior and medial-lateral [ Time Frame: 2 months ] [ Designated as safety issue: Yes ]
This outcome measure quantified by the difference between the maximum values ​​of the anterior-posterior and medial-lateral after the start of trial and average position in the axis anteroposterior and mediolateral, respectively, in the 200 ms prior to the onset of the trial.
center of pressure [ Time Frame: 2 months ] [ Designated as safety issue: Yes ]
Complete list of historical versions of study NCT01912794 on ClinicalTrials.gov Archive Site
Coordination between the hip and ankle joint [ Time Frame: 2 months ] [ Designated as safety issue: Yes ]
Coordination between the hip and ankle joints, which is evaluated by adjusting the angle displacement data, hip and ankle angle within 95% of an ellipse surrounding the values ​​of the disturbance moment until the end of the trial. Will be carried out a regression analysis to identify the slope of the fitted ellipse. Slopes greater indicate a greater share of the ankle in relation to the hip
Not Provided
Muscle activation latency [ Time Frame: 2 months ] [ Designated as safety issue: Yes ]
This outcome measure is time between the time of release and the first load value 3 standard deviations above the mean magnitude in the 200 ms prior to postural disturbance, with subsequent values ​​increasing.
Not Provided
 
Postural Responses to External Perturbation in Post-Stroke
Postural Responses to External Perturbation in Post-Stroke: Sensorimotor Integration and Rehabilitation

To maintain stable body balance in daily activities, the ability to respond to external perturbations is an essential factor. Such capacity is limited in pathological conditions, such as in stroke, in which postural control is impaired due to lesions to the central nervous system. Impairment to postural control increases body sway during upright posture and leads to augmented frequency of falls. In this sense, the identification of mechanisms involved in body balance disorders after stroke is particularly important in situations of postural perturbation. The purpose of this project is to evaluate reactive postural responses to unpredictable external perturbations, analyzing postural dysfunctions caused by lesion to different brain areas as a result of stroke, and test principles of dynamic body balance rehabilitation.

Not Provided
Interventional
Not Provided
Endpoint Classification: Safety/Efficacy Study
Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Treatment
Stroke
Other: Sensory Intervention
  1. full sensory information, whose participants will practice balancing tasks without constraint sensory body;
  2. sensory constraint, whose participants will practice the same balance tasks with constraint body of visual and tactile information from the soles of the feet;
  3. control, whose participants will exercise activities involving cognitive and upper limbs.
Experimental: Sensory Conditions
Intervention: Other: Sensory Intervention
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Not yet recruiting
24
October 2014
February 2014   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • Inclusion criteria are as follows. Healthy participants: absence of detectable neurological or physical malfunction which might affect postural control, no use of drugs affecting body balance and preserved mental capacity. Stroke patients: capacity to sustain independently orthostatic posture for at least 5 min. and preserved mental capacity.

Exclusion Criteria:

  • Exclusion Criteria are: no orthopedic malfunction, no clinical instability associated with systemic disease, no use of drugs affecting body balance and presence of "pusher syndrome".
Both
45 Years to 70 Years
No
Contact: Alessandra R Martinelli, Master +551681490337 lerezendemartinelli@yahoo.com.br
Brazil
 
NCT01912794
SMH-2011/18173-3
Yes
Alessandra Rezende Martinelli, University of Sao Paulo
University of Sao Paulo
Not Provided
Study Director: Luis A Teixeira, PhD
University of Sao Paulo
July 2013

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP