Effects of Navigated Repetitive Transcranial Magnetic Stimulation According to Post-stroke Aphasia Types

This study has been completed.
Sponsor:
Information provided by (Responsible Party):
Nam-Jong Paik, Seoul National University Bundang Hospital
ClinicalTrials.gov Identifier:
NCT01877161
First received: March 11, 2013
Last updated: May 20, 2014
Last verified: May 2014

March 11, 2013
May 20, 2014
December 2012
May 2013   (final data collection date for primary outcome measure)
The Change of Reaction Time Between Before and After Stimulation in Each Session (MTG, STG, Sham) [ Time Frame: change between before and after the TMS stimulation for each sessions (at session 1, session 2, session 3) ] [ Designated as safety issue: No ]

Reaction time for lexical and repetition test were measured before and after the TMS stimulation at each sessions (at session 1, session 2, session 3 over MTG/STG/Sham).

Response times were measured via the response pad, and spoken responses were recorded via a SV-1 Voice Key apparatus.

The "reaction time post TMS - reaction time pre TMS" were used for analysis.* Arm/Group Title Arm/Group Description Maximum length (999) Repetitive magnetic stimulation (rTMS) were applied over STG

Reaction time [ Time Frame: change between before and after the TMS stimulation for each day (at Day 1, Day 2, Day 3) ] [ Designated as safety issue: No ]
reaction time for lexical and repetition test
Complete list of historical versions of study NCT01877161 on ClinicalTrials.gov Archive Site
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Effects of Navigated Repetitive Transcranial Magnetic Stimulation According to Post-stroke Aphasia Types
Effects of Navigated Repetitive Transcranial Magnetic Stimulation According to Post-stroke Aphasia Types

Repetitive transcranial magnetic stimulation induced virtual lesions for aphasia.

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Interventional
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Allocation: Randomized
Endpoint Classification: Safety Study
Intervention Model: Crossover Assignment
Masking: Single Blind (Subject)
Primary Purpose: Treatment
  • To Healthy Volunteer
  • Virtual Lesions for Aphasia
  • Device: Repetitive magnetic stimulation to superior temporal gyrus
    Repetitive magnetic stimulation to superior temporal gyrus
    Other Name: MagPro X100 magnetic stimulator
  • Device: Repetitive magnetic stimulation to middle temporal gyrus
    Repetitive magnetic stimulation to middle temporal gyrus
    Other Name: MagPro X100 magnetic stimulator
  • Device: Repetitive magnetic stimulation (Sham)
    Repetitive magnetic stimulation (Sham)
    Other Name: MagPro X100 magnetic stimulator
  • Experimental: Middle temporal gyrus
    Repetitive magnetic stimulation to middle temporal gyrus
    Intervention: Device: Repetitive magnetic stimulation to middle temporal gyrus
  • Sham Comparator: Control group
    Repetitive magnetic stimulation (Sham)
    Intervention: Device: Repetitive magnetic stimulation (Sham)
  • Experimental: Superior temporal gyrus
    Repetitive magnetic stimulation to superior temporal gyrus
    Intervention: Device: Repetitive magnetic stimulation to superior temporal gyrus
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*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
12
May 2013
May 2013   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • fluent in Korean
  • older than 18 years old

Exclusion Criteria:

  • younger than 18 years old
  • psychotic or psychiatric problems
  • pregnant
  • contraindications to MRI/fMRI
  • uncooperative
  • metalic implants, pacemaker or cochlear implants
  • cannot perform outcome measure-related task
  • known seizure history
Both
18 Years and older
Yes
Contact information is only displayed when the study is recruiting subjects
Korea, Republic of
 
NCT01877161
E-1206-158-003
Not Provided
Nam-Jong Paik, Seoul National University Bundang Hospital
Seoul National University Bundang Hospital
Not Provided
Not Provided
Seoul National University Bundang Hospital
May 2014

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP