Assessment of Coronary Artery Disease in Stroke Patients (ACADIS)

This study is currently recruiting participants. (see Contacts and Locations)
Verified May 2013 by Seoul National University Hospital
Sponsor:
Collaborator:
National Reserch Foundation of Korea
Information provided by (Responsible Party):
Seoul National University Hospital
ClinicalTrials.gov Identifier:
NCT01850693
First received: May 3, 2013
Last updated: May 6, 2013
Last verified: May 2013

May 3, 2013
May 6, 2013
January 2006
December 2013   (final data collection date for primary outcome measure)
MACE (Major Adverse Cardiac Event) [ Time Frame: Participants will be followed until Dec. 2013, an expeded average of 5 years ] [ Designated as safety issue: No ]
MACE was included as follows: 1) all-cause mortality, 2) myocardial infarction, 3) unstable angina requiring hospitalization
Same as current
Complete list of historical versions of study NCT01850693 on ClinicalTrials.gov Archive Site
Revascularization [ Time Frame: Participants will be followed until Dec. 2013, an expeded average of 5 years ] [ Designated as safety issue: No ]
However, early revascularization less than 90days after CCTA scan is excluded from events, because these subjects directly affected by CT findings
Same as current
Repeated stroke [ Time Frame: Participants will be followed until Dec. 2013, an expeded average of 5 years ] [ Designated as safety issue: No ]
newly developed stroke after CCTA scan
Same as current
 
Assessment of Coronary Artery Disease in Stroke Patients
Prevalence and Characteristics of Coronary Atherosclerosis in Stroke Patients Using Coronary CT Angiography

This study is to evaluate the prevalence, plaque characteristics (plaque types, stenosis degree, remodeling) and predictors of coronary atherosclerosis in stroke patients with coronary CT angiography.

Stroke and coronary artery disease (CAD) share common risk factors and pathological mechanisms. CAD is an important cause of death in patients with stroke.

Currently, coronary CT angiography (CCTA) is very useful non-invasive tool for detection of CAD and plaque analysis.

Therefore, the investigators aimed to evaluate the prevalence, plaque characteristics (plaque types, stenosis degree, remodeling) and predictors of CAD in stroke patients through follow-up (more than 5 years) using CCTA.

Observational [Patient Registry]
Observational Model: Cohort
Time Perspective: Prospective
5 Years
Not Provided
Non-Probability Sample

Stroke patients on the basis of TOAST classification

Coronary Artery Disease
Not Provided
Coronary artery disease, Stroke
Coronary artery disease, stroke, coronary CT angiography
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Recruiting
2500
December 2015
December 2013   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • Stroke patients who diagnosed by clinical and brain imaging
  • Who performed coronary CT angiography between 2006 and 2012

Exclusion Criteria:

  • Traumatic brain injury or traumatic stroke patients
  • Previous myocardial infarction or coronary artery disease
  • Previously performed percutaneous coronary intervention (PCI), coronary artery bypass graft (CABG) or other cardiac surgery
  • Insufficient medical record
  • Poor image quality of CCTA scan
Both
30 Years and older
No
Contact: Eun Ju Chun, MD +82-31-787-7618 drejchun@daum.net
Contact: Eun Hee Kim, MD +82-31-787-7609 xmida@hanmail.net
Korea, Republic of
 
NCT01850693
NRF 2010-0023504
Not Provided
Seoul National University Hospital
Seoul National University Hospital
National Reserch Foundation of Korea
Principal Investigator: Eun Ju Chun, MD Department of Radiology, Seoul National University Bundang Hospital
Seoul National University Hospital
May 2013

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP