Adiponectin and Ethnic Differences in Insulin Resistance

This study has been completed.
Sponsor:
Information provided by (Responsible Party):
University of Colorado, Denver
ClinicalTrials.gov Identifier:
NCT01831102
First received: April 5, 2013
Last updated: April 9, 2013
Last verified: April 2013

April 5, 2013
April 9, 2013
March 2011
August 2011   (final data collection date for primary outcome measure)
total adiponectin concentration [ Time Frame: measured once during second study visit, in fasting condition ] [ Designated as safety issue: No ]
Same as current
Complete list of historical versions of study NCT01831102 on ClinicalTrials.gov Archive Site
Insulin sensitivity [ Time Frame: Measured once, during second study visit. ] [ Designated as safety issue: No ]
Calculated from insulin and glucose values obtained during IV glucose tolerance test.
Same as current
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Not Provided
 
Adiponectin and Ethnic Differences in Insulin Resistance
Adiponectin as an Independent Determinant of Ethnic Differences in Insulin Resistance

The purpose of this protocol is to measure and compare levels of the circulating protein adiponectin and adiponectin's association with insulin sensitivity in Mexican Americans and non-Latino white subjects. The investigators also aimed to examine associations between nutritional factors and adiponectin levels.

Not Provided
Observational
Observational Model: Case-Only
Time Perspective: Cross-Sectional
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Non-Probability Sample

Community sample

  • Insulin Resistance
  • Type 2 Diabetes
Other: none- observational study
  • non-Latino white
    no Latino ancestry, Caucasian
    Intervention: Other: none- observational study
  • Mexican American
    Mexican American ancestry
    Intervention: Other: none- observational study
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
43
August 2011
August 2011   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • 18-60 years of age
  • BMI 20.0-34.9 m/kg2
  • Mexican American with at least 3 grandparents born in Mexico or white with no grandparents of Latino descent.

Exclusion Criteria:

  • pregnancy
  • breastfeeding
  • diabetes mellitus
  • blood pressure > 160/100 mmHg
  • creatinine > 1.5 mg/dl or glomerular filtration rate (GFR) < 60
  • liver function tests > 3x upper limit of normal (ULN)
  • h/o heart failure
  • h/o eating disorder
Both
18 Years to 60 Years
Yes
Contact information is only displayed when the study is recruiting subjects
United States
 
NCT01831102
10-1260
Not Provided
University of Colorado, Denver
University of Colorado, Denver
Not Provided
Principal Investigator: Rocio Pereira, MD University of Colorado, Denver
University of Colorado, Denver
April 2013

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP