A Study of Quantitative Assessments of Angle Width in Chinese Patients With Open-angle Glaucoma and/or Ocular Hypertension

This study has been terminated.
(Study terminated due to corporate decision.)
Sponsor:
Information provided by (Responsible Party):
Allergan
ClinicalTrials.gov Identifier:
NCT01781962
First received: January 30, 2013
Last updated: July 30, 2014
Last verified: July 2014

January 30, 2013
July 30, 2014
January 2013
June 2013   (final data collection date for primary outcome measure)
Anterior Angle Width Using Anterior Segment Optical Coherence Tomography (AS OCT) [ Time Frame: Day 1 ] [ Designated as safety issue: No ]
The angle width formed between the eye's cornea and iris in both eyes was measured in microns (µm) using AS OCT, a laser-based, noninvasive, diagnostic system providing high-resolution images of the eye.
Anterior Angle Width as Measured by Anterior Segment Optical Coherence Tomography [ Time Frame: Day 1 ] [ Designated as safety issue: No ]
Complete list of historical versions of study NCT01781962 on ClinicalTrials.gov Archive Site
  • Number of Study Eyes in Each Shaffer Grade Using Gonioscopic Lens [ Time Frame: Day 1 ] [ Designated as safety issue: No ]
    The angle width formed between the cornea and iris in both eyes was measured by gonioscopy using Shaffer grading where: grade 4=wide open, grade 3=moderately open, grade 2=moderately narrow, grade 1=very narrow or grade 0=closed. The number of eyes in each Shaffer Grade is reported.
  • Number of Study Eyes in Each Step Grade Using Gonioscopic Lens [ Time Frame: Day 1 ] [ Designated as safety issue: No ]
    The angle width formed between the cornea and iris in both eyes was measured by gonioscopy using Large Step Grading ranging from 1.0 (smallest angle width) to 7.5 (largest angle width) with 0.5 unit intervals where each Large Step unit represented a fixed length of approximately 200 µm. The number of eyes in each Large Step Grade is reported.
  • Anterior Angle Width as Measured by Gonioscopic Lens with Shaffer Grading [ Time Frame: Day 1 ] [ Designated as safety issue: No ]
  • Anterior Angle Width as Measured by Gonioscopic Lens with Step Grading [ Time Frame: Day 1 ] [ Designated as safety issue: No ]
Not Provided
Not Provided
 
A Study of Quantitative Assessments of Angle Width in Chinese Patients With Open-angle Glaucoma and/or Ocular Hypertension
Not Provided

This study will assess angle width in Chinese patients with Open-angle Glaucoma and/or Ocular Hypertension.

Not Provided
Observational
Observational Model: Cohort
Time Perspective: Prospective
Not Provided
Not Provided
Probability Sample

Chinese patients with Open-angle Glaucoma and/or Ocular Hypertension

  • Open-angle Glaucoma
  • Ocular Hypertension
Other: No Treatment
No Treatment was given in this study.
All Participants
Open-Angle Glaucoma (OAG) and/or Ocular Hypertension (OHT) patients.
Intervention: Other: No Treatment
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Terminated
206
June 2013
June 2013   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • Of Chinese descent
  • Open-angle Glaucoma or Ocular Hypertension in each eye

Exclusion Criteria:

  • History of a narrow-angle or angle closure glaucoma
  • Angle abnormalities in either eye
Both
18 Years and older
No
Contact information is only displayed when the study is recruiting subjects
China
 
NCT01781962
192024-077
No
Allergan
Allergan
Not Provided
Study Director: Medical Director Allergan
Allergan
July 2014

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP