Alcohol Harm Reduction Intervention Among Female Sex Workers in Mombasa, Kenya

This study is ongoing, but not recruiting participants.
Sponsor:
Collaborator:
United States Agency for International Development (USAID)
Information provided by (Responsible Party):
FHI 360
ClinicalTrials.gov Identifier:
NCT01756469
First received: December 20, 2012
Last updated: March 25, 2014
Last verified: March 2014

December 20, 2012
March 25, 2014
March 2011
October 2012   (final data collection date for primary outcome measure)
Alcohol use and STI/HIV infection [ Time Frame: up to 12 months ] [ Designated as safety issue: No ]
Outcomes assessed at up to 12 months follow-ups
Same as current
Complete list of historical versions of study NCT01756469 on ClinicalTrials.gov Archive Site
Condom use and sexual violence [ Time Frame: up to 12 months ] [ Designated as safety issue: No ]
Outcomes assessed at up to 12 months follow-ups
Same as current
Not Provided
Not Provided
 
Alcohol Harm Reduction Intervention Among Female Sex Workers in Mombasa, Kenya
Alcohol Harm Reduction Intervention Among Female Sex Workers in Mombasa, Kenya

The main study objective is to investigate whether female sex workers (FSWs) at drop-in centers in Mombasa, Kenya, who report harmful or hazardous alcohol intake and participate in a brief alcohol intervention (vs. those who participate in a nutrition intervention in the control group), will reduce their alcohol use and incidence of STIs, HIV, and sexual violence, as well as increase their condom use.

This is a longitudinal intervention study among female sex workers affiliated with the APHIA II program, who have harmful or hazardous alcohol use patterns. The purpose of the study is to obtain initial estimates of the impact of the intervention on alcohol use and STI acquisition, to help determine if this is a program that should be implemented more fully. Female sex workers will be recruited from three APHIA drop-in centers in Mombasa district, Kenya who serve more than 15,000 FSWs. Approximately 800 FSWs with harmful or hazardous alcohol use will be enrolled in the study over a six-month accrual period with a follow-up of 12 months for each participant. FSWs will be randomly assigned to either the intervention or "active" control arm. The intervention arm will receive the Brief Intervention for Alcohol Use (BI), which is designed for individuals with harmful or hazardous alcohol use, in addition to information about nutrition. The control arm will receive only non-alcohol related information about nutrition during the study period. A peer educator from the APHIA II project will inform potential participants about the study. A trained nurse counselor or research assistant will then screen interested volunteers for harmful alcohol use with the validated AUDIT questionnaire (WHO, 2001) and obtain informed consent from eligible participants. Arm assignment using random allocation will be made after volunteers are screened for eligibility, provide consent for participation, and complete baseline data collection procedures. Follow-up data collection will occur at six and twelve months post-randomization. Data collection procedures at all three time points will include the AUDIT questionnaire, a behavioral interview, a gynecological exam including STI diagnosis and treatment, and a HIV rapid test and counseling.

Interventional
Not Provided
Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Single Blind (Investigator)
Primary Purpose: Prevention
Alcohol Use and STI/HIV Infections, Domestic Violence
Behavioral: Behavioral Intervention for Alcohol Use
Behavioral Intervention for Alcohol Use
Other Name: BI
  • No Intervention: Control
    non-alcohol related information about nutrition
  • Active Comparator: Intervention
    Behavioral Intervention for Alcohol Use
    Intervention: Behavioral: Behavioral Intervention for Alcohol Use
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Active, not recruiting
818
October 2015
October 2012   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • Female sex worker, defined as a woman who self reports exchange of any type of sex including oral, anal, and vaginal sex for money or gifts within the six months prior to study enrollment;
  • Self-identifies as a woman;
  • 18 years or older;
  • Scores between 7-19 on the AUDIT questionnaire;
  • Willing to participate in the study and all data collection procedures;
  • Lives in Mombasa or plans on residing in Mombasa for 12 months following study enrollment;
  • Currently participating in the APHIA II sex worker peer education program; and
  • Documentation of negative tests for gonorrhea, Chlamydia, and trichomoniasis.

Exclusion Criteria:

  • Scores less than 7 (low-risk drinking) or more than 19 (high-risk drinking/alcohol dependence) on the AUDIT questionnaire;
  • Plans to be away in the next 12 months for more than six months or relocate away from the study site;
  • Currently participating in another HIV intervention study; or
  • Has any other condition that, in the opinion of the investigator or designee, would preclude provision of informed consent, make participation in the study unsafe, complicate interpretation of study outcome data, or otherwise with achieving the study objectives.
Female
18 Years and older
Yes
Contact information is only displayed when the study is recruiting subjects
Kenya
 
NCT01756469
PHE#KE.09.0235
No
FHI 360
FHI 360
United States Agency for International Development (USAID)
Principal Investigator: Peter Mwarogo, MPH FHI 360
FHI 360
March 2014

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP