Tailored Intervention to Improve Medication Adherence in Patients With Hypertension

This study is ongoing, but not recruiting participants.
Sponsor:
Collaborator:
University of Southern Denmark
Information provided by (Responsible Party):
Ulla Hedegaard, Odense University Hospital
ClinicalTrials.gov Identifier:
NCT01742923
First received: December 4, 2012
Last updated: June 20, 2014
Last verified: June 2014

December 4, 2012
June 20, 2014
December 2012
February 2014   (final data collection date for primary outcome measure)
Percent of patients that are at least 80% adherent (Medication possession rate > 0.8) to antihypertensives and statins [ Time Frame: One year from inclusion ] [ Designated as safety issue: No ]
Same as current
Complete list of historical versions of study NCT01742923 on ClinicalTrials.gov Archive Site
  • Non-persistence with antihypertensives and statins measured by percent of patients that are not supplied with medications for more than three continuous months [ Time Frame: One year from inclusion ] [ Designated as safety issue: No ]
  • Reduction in systolic and diastolic blood pressure [ Time Frame: One year from inclusion ] [ Designated as safety issue: No ]
  • Composite endpoint (stroke, myocardial infarction or cardiovascular death) [ Time Frame: One year from inclusion ] [ Designated as safety issue: No ]
Same as current
Not Provided
Not Provided
 
Tailored Intervention to Improve Medication Adherence in Patients With Hypertension
Pharmacist Intervention Programme in Secondary Care to Improve Medication Adherence in Patients With Hypertension

Patients with hypertension have an increased risk of stroke and myocardial infarction. However, poor adherence to treatment with antihypertensives and lipid-lowering agents occurs frequently within this patient group. The purpose of this study is to investigate whether a complex tailored intervention in a hospital setting will lead to increased medication adherence and fewer cardiovascular events when compared to a usual care group. Interventions focus on motivational interviewing, medication review and telephone follow up.

Not Provided
Interventional
Not Provided
Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Single Blind (Outcomes Assessor)
Primary Purpose: Prevention
Hypertension
  • Behavioral: Complex tailored intervention
  • Behavioral: Usual care
  • Placebo Comparator: Usual care
    Usual care
    Intervention: Behavioral: Usual care
  • Experimental: Complex tailored intervention

    The interventions consists of 3 elements:

    1. Medication review with recommendations focused on antihypertensives and statins and adherence to guidelines and patient´s adherence to medications
    2. Consultation with a pharmacist using motivational interviewing techniques
    3. Follow-up telephone calls one month and six months after inclusion
    Intervention: Behavioral: Complex tailored intervention
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Active, not recruiting
400
September 2014
February 2014   (final data collection date for primary outcome measure)

Inclusion Criteria:

Age: 18 years or older

  • Patients receiving ambulatory treatment for hypertension in a hospital setting
  • The patient or a carer usually dispenses the patient's medications
  • Patient lives in the Southern Region of Denmark
  • Written consent

Exclusion Criteria:

  • Lives in a care home or institution
  • Receive dose dispensed medicine from a pharmacy
  • Medicine is dispensed by a nurse in the patient's home
  • Correctional mental health patients
Both
18 Years and older
No
Contact information is only displayed when the study is recruiting subjects
Denmark
 
NCT01742923
AKF-384
No
Ulla Hedegaard, Odense University Hospital
Odense University Hospital
University of Southern Denmark
Not Provided
Odense University Hospital
June 2014

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP