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Effect of Modified Fujita Technique Uvulopalatoplasty on Oxidative DNA Damage Levels in Patients With Obstructive Sleep Apnea SyndromE (OSAS)

This study has been completed.
Sponsor:
Information provided by (Responsible Party):
Vural Fidan, Erzurum Regional Training & Research Hospital
ClinicalTrials.gov Identifier:
NCT01635699
First received: July 4, 2012
Last updated: July 6, 2012
Last verified: July 2012
History of Changes

July 4, 2012
July 6, 2012
June 2008
June 2008   (final data collection date for primary outcome measure)
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Not Provided
Complete list of historical versions of study NCT01635699 on ClinicalTrials.gov Archive Site
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Effect of Modified Fujita Technique Uvulopalatoplasty on Oxidative DNA Damage Levels in Patients With Obstructive Sleep Apnea SyndromE (OSAS)
Effect of Modified Fujita Technique Uvulopalatoplasty on Oxidative DNA Damage Levels in Patients With Obstructive Sleep Apnea SyndromE

The purpose of this study is to determine the possible effects of uvulopalatopharngoplasty (UPPP) -which is a a therapy used on patients with Obstructive sleep apnea syndrome (OSAS- on oxidative damage.

Obstructive sleep apnea syndrome (OSAS) is a sydrome which has characteristic upper way obstruction and a decrease in blood oxygen saturation as sleeping. uvulopalatopharngoplasty (UPPP)is one of the surgical approaches applied to the patients with OSAS, since the oxidative damage markers have been found high in patients with OSAS. Although antioxidant levels were higher in patients with OSAS than those in normal population, there is report about the effect of UPPP on antioxidant status in patients with OSAS. We performed this study to confirm whether is there a We performed the present study to confirm whether there is a relationship between the OSAS and oxidative damage before and after UPPP.
Observational
Observational Model: Case-Only
Time Perspective: Prospective
Not Provided
Retention:   Samples Without DNA
Description:

serum, whole blood
Probability Sample

Patients who underwent uvulopalatopharngoplasty (UPPP)for Obstructive sleep apnea syndrome (OSAS) at the otolaryngology department of our hospital in Erzurum, Turkey.
Sleep Apnea, Obstructive
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*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
49
March 2011
June 2008   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • Patients who underwent uvulopalatopharngoplasty (UPPP)for Obstructive sleep apnea syndrome (OSAS)

Exclusion Criteria:

  • Anormal nasopharyngeal computed tomography, chronic diseases such as diabetes mellitus, hypertension etc.
Both
18 Years and older
No
Contact information is only displayed when the study is recruiting subjects
Turkey
 
NCT01635699
ATUNI-1
No
Vural Fidan, Erzurum Regional Training & Research Hospital
Erzurum Regional Training & Research Hospital
Not Provided
Principal Investigator: vural fidan, operating surgeon doctor eskisehir yunus emre state hospital (still works here)
Erzurum Regional Training & Research Hospital
July 2012

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP