Executive Functioning and Mindfulness in Adults With Attention Deficit/Hyperactivity Disorder Imaging (EFMImaging)

This study has been withdrawn prior to enrollment.
(study close-out)
Sponsor:
Information provided by (Responsible Party):
Duke University
ClinicalTrials.gov Identifier:
NCT01629914
First received: June 26, 2012
Last updated: January 28, 2013
Last verified: January 2013

June 26, 2012
January 28, 2013
June 2012
January 2013   (final data collection date for primary outcome measure)
change from baseline in blood-oxygenation-level-dependent (BOLD) fMRI signal [ Time Frame: baseline and 8-weeks ] [ Designated as safety issue: No ]
Participants will be scanned prior to and following an 8-week group-based mindfulness meditation intervention
Same as current
Complete list of historical versions of study NCT01629914 on ClinicalTrials.gov Archive Site
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Executive Functioning and Mindfulness in Adults With Attention Deficit/Hyperactivity Disorder Imaging
Executive Functioning and Mindfulness in Adults With ADHD Imaging

The main purpose of this study is to evaluate changes in brain functioning using an MRI machine following mindfulness meditation training.

The broad objective of this proposal is to identify functional neuroanatomical correlates of changes in executive brain functioning prior to and following an 8-week, group-based mindfulness meditation intervention within a group of 10 adults diagnosed with Attention-deficit/hyperactivity disorder (ADHD). Another group of 10 adults diagnosed with ADHD will be placed in the waitlist condition.

Our primary hypothesis is that adults with ADHD in the treatment group will exhibit improved performance on a series of executive functioning tasks and that exposure to task stimuli will correspond to changes in neural functioning following an 8-week, group-based mindfulness intervention. Brain responses will be measured using blood-oxygenation-level-dependent (BOLD) fMRI signal in brain regions associated with emotional and executive processes prior to and following treatment.

Interventional
Not Provided
Intervention Model: Single Group Assignment
Masking: Open Label
Attention-deficit/Hyperactivity Disorder
Behavioral: Mindfulness Meditation
8-week, group-based mindfulness meditation intervention
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*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Withdrawn
0
January 2013
January 2013   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • ages 18-50 years
  • meet DSM-IV criteria for ADHD
  • intellectual functioning ≥ 80 as assessed by an IQ screener
  • generally healthy (i.e., no major medical problems)

Exclusion Criteria:

  • major medical condition that would make participation unsafe (e.g., have pacemaker or other metallic implant), uncomfortable (e.g., chronic pain)
  • claustrophobic, or abnormally afraid of closed-in places
  • current drug use
Both
18 Years to 50 Years
Yes
Contact information is only displayed when the study is recruiting subjects
Not Provided
 
NCT01629914
Pro00037192
No
Duke University
Duke University
Not Provided
Principal Investigator: John T Mitchell, Ph.D Duke University
Duke University
January 2013

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP