Vascular Subphenotypes of Lung Disease in HIV & COPD (VAST)

The recruitment status of this study is unknown because the information has not been verified recently.
Verified April 2012 by University of Pittsburgh.
Recruitment status was  Recruiting
Sponsor:
Information provided by (Responsible Party):
University of Pittsburgh
ClinicalTrials.gov Identifier:
NCT01581086
First received: April 17, 2012
Last updated: April 19, 2012
Last verified: April 2012

April 17, 2012
April 19, 2012
January 2012
Not Provided
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Complete list of historical versions of study NCT01581086 on ClinicalTrials.gov Archive Site
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Vascular Subphenotypes of Lung Disease in HIV & COPD
Identify and Characterize Populations at Risk for Developing Pulmonary Arterial Hypertension (PAH)

This study is looking for high blood pressure in the lungs (Pulmonary artery hypertension PAH) in HIV and COPD patients.

Not Provided
Observational
Observational Model: Cohort
Time Perspective: Retrospective
Not Provided
Retention:   Samples With DNA
Description:

Whole Blood

Non-Probability Sample

Pitt mens Study(MACS).

University of Pittsburgh HIV Clinic(PACT).

Emphysema COPD Research Center Research Registry(ECRC).

Pulmonary Artery Hypertension
Not Provided
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*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Recruiting
140
January 2014
Not Provided

Inclusion Criteria:

  • Male/Female 18-80 years of age.
  • Subject has been previously enrolled in PACT/MAC/ECRC study.
  • Must have recent ProBNP test >120pg/ml or abnormal echocardiogram (right ventricular systolic pressure >or=40mmHg) without evidence of left sided heart failure.

Exclusion Criteria:

  • Previous diagnosis of congenital heart failure.
  • If evidence of Left ventricular systolic or diastolic dysfunction, echo will be reviewed by the PI on a case by case basis.
  • Creatine clearance <60ml/min per 1.73 m2.
  • Undiagnosed chest pain or myocardial infarction, stroke or cardiovascular event within 3 months.
  • Pregnancy.
  • Subjects receiving chronic anticoagulant.
  • Inability to complete the 6 minute walk test.
Both
18 Years to 80 Years
No
Contact: Tammi F Lawther, BS 412-624-8295 lawthertf@upmc.edu
United States
 
NCT01581086
VAST11060550
Yes
University of Pittsburgh
University of Pittsburgh
Not Provided
Principal Investigator: Hunter C Champion, MD University of Pittsburgh
University of Pittsburgh
April 2012

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP