Clinical Characteristics, Management and Outcomes of Chinese Patients With Acute Aortic Dissection (CCMOCPAAD)

This study is currently recruiting participants.

Verified March 2012 by Xijing Hospital

Sponsor:

Information provided by (Responsible Party):

Yang Li, MD, Xijing Hospital

ClinicalTrials.gov Identifier:

NCT01552720

First received: March 7, 2012

Last updated: March 12, 2012

Last verified: March 2012

History of Changes

Tracking Information

First Received Date ^ICMJE

March 7, 2012

Last Updated Date

March 12, 2012

Start Date ^ICMJE

January 2011

Estimated Primary Completion Date

November 2015 (final data collection date for primary outcome measure)

Current Primary Outcome Measures ^ICMJE

Not Provided

Original Primary Outcome Measures ^ICMJE

Not Provided

Change History

Complete list of historical versions of study NCT01552720 on ClinicalTrials.gov Archive Site

Current Secondary Outcome Measures ^ICMJE

Not Provided

Original Secondary Outcome Measures ^ICMJE

Not Provided

Current Other Outcome Measures ^ICMJE

Not Provided

Original Other Outcome Measures ^ICMJE

Not Provided

Descriptive Information

Brief Title ^ICMJE

Clinical Characteristics, Management and Outcomes of Chinese Patients With Acute Aortic Dissection

Official Title ^ICMJE

Clinical Investigation of Chinese Patients With Aortic Dissection

Brief Summary

Data reported by the international registry of acute aortic dissection (IRAD) in not sufficient to reflect clinical characteristics of acute aortic dissection in China. Moreover, clinical characteristics of Acute aortic dissection have not evaluated to data. The aim of this study is analyze changing trend of clinical characteristics of Chinese patients with acute aortic dissection.

Detailed Description

Acute aortic dissection is the most common aortic emergency, with an annual incidence of 3-5 cases per 100 000 population. About 50% of these patients are dead within 48 hours, if untreated. To assess the clinical manifestation, diagnosis, management, and outcomes of patients with AAD, the International Registry of Acute Aortic Dissection (IRAD) was established in 1996, and has grown to include about 2000 patients from 26 large referral centers to date. All patients from IRAD are caucasians from developed countries wiht advanced medical care, however, the proportion of Asian is very low. Data reported by the IRAD in not sufficient to reflect clinical characteristics of Acute aortic dissection in China. Clinical characteristics of Chinese patients with acute aortic dissection have not evaluated to data. The aim of this study is to analyze clinical characteristics of Chinese patients with acute aortic dissection and clinical trend of acute aortic dissection.

Study Type ^ICMJE

Observational

Study Design ^ICMJE

Observational Model: Case-Only
Time Perspective: Retrospective

Target Follow-Up Duration

Not Provided

Biospecimen

Not Provided

Sampling Method

Probability Sample

Study Population

Chinese patients suffering acute aortic dissection

Condition ^ICMJE

Aortic Dissection

Intervention ^ICMJE

Not Provided

Study Group/Cohort (s)

Not Provided

Publications *

Not Provided

* Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.

Recruitment Information

Recruitment Status ^ICMJE

Recruiting

Estimated Enrollment ^ICMJE

5000

Estimated Completion Date

December 2015

Estimated Primary Completion Date

November 2015 (final data collection date for primary outcome measure)

Eligibility Criteria ^ICMJE

Inclusion Criteria:

Clinical diagnosis of acute aortic dissection
Type A dissection
Type B dissection
Retrograde type B dissection

Exclusion Criteria:

Aortic aneurysm
Myocardial infarction
Cerebral accident
Active infection
Unwillingness to cooperation with study procedures or follow-up visits

Gender

Both

Ages

18 Years to 80 Years

Accepts Healthy Volunteers

Contacts ^ICMJE

Contact: Yang Li, MD

029-6787564

liyangcenter@sina.com

Location Countries ^ICMJE

China

Administrative Information

NCT Number ^ICMJE

NCT01552720

Other Study ID Numbers ^ICMJE

XJHEART2012, CRAD201203

Has Data Monitoring Committee

Yes

Responsible Party

Yang Li, MD, Xijing Hospital

Study Sponsor ^ICMJE

Xijing Hospital

Collaborators ^ICMJE

Not Provided

Investigators ^ICMJE

Study Director:

Dihua Yi, PhD, MD

Xijing Hospital

Information Provided By

Xijing Hospital

Verification Date

March 2012

^ICMJE Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP

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