Free Fatty Acids: Threshold Repeatability Study

This study has been completed.
Sponsor:
Information provided by (Responsible Party):
Richard Mattes, Purdue University
ClinicalTrials.gov Identifier:
NCT01550120
First received: March 7, 2012
Last updated: November 21, 2013
Last verified: March 2013

March 7, 2012
November 21, 2013
March 2012
November 2013   (final data collection date for primary outcome measure)
  • Non-esterified fatty acid detection thresholds in humans [ Time Frame: 6 months ] [ Designated as safety issue: No ]
  • BMI [ Time Frame: Baseline ] [ Designated as safety issue: No ]
Same as current
Complete list of historical versions of study NCT01550120 on ClinicalTrials.gov Archive Site
  • Habitual fat intake [ Time Frame: Baseline ] [ Designated as safety issue: No ]
    Block Rapid Dietary Fat Screener will be used as well as the ASA-24.
  • testing method [ Time Frame: 6 months ] [ Designated as safety issue: No ]
    Comparison of time to maximum sensitivity by participants based on forced-choice versus staircase stimulus presentation techniques.
  • hunger [ Time Frame: each visit ] [ Designated as safety issue: No ]
    Visual analog scale
  • Habitual fat intake [ Time Frame: Baseline ] [ Designated as safety issue: No ]
    Block Rapid Dietary Fat Screener will be used
  • BMI [ Time Frame: Baseline ] [ Designated as safety issue: No ]
    Is threshold sensitivity associated with BMI?
  • Sex/Gender [ Time Frame: Begining of study ] [ Designated as safety issue: No ]
  • testing method [ Time Frame: 6 months ] [ Designated as safety issue: No ]
    Comparison of time to maximum sensitivity by participants based on forced-choice versus staircase stimulus presentation techniques.
Not Provided
Not Provided
 
Free Fatty Acids: Threshold Repeatability Study
Free Fatty Acids: Threshold Repeatability Study

This study seeks to determine if non-esterified fatty acid (NEFA) taste detection thresholds change with repeated testing. Threshold testing for NEFA taste has been reported by a number of laboratories, including our own; however, these studies have reported data for only one testing occasion. The investigators seek to conduct repeated testing to measure the test-retest reliability of these methods. The investigators believe that with repeated exposure to NEFA, a person's sensitivity increases. The investigators are also testing the efficiency of testing by two methods (forced-choice ascending trial versus staircase). Additionally, the association between taste responses, diet and BMI will be explored.

Not Provided
Observational
Observational Model: Case-Crossover
Time Perspective: Prospective
Not Provided
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Non-Probability Sample

Participants between the ages of 18 and 55 years of age from any ethnic background who are in good health and are available for the next three months will be recruited. Additionally, equal numbers of lean and overweight participants will be sought.

Taste, Non-esterified Fatty Acids
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Not Provided
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*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
48
November 2013
November 2013   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • 18-55 years old
  • in good health
  • available for three months

Exclusion Criteria:

Both
18 Years to 55 Years
Yes
Contact information is only displayed when the study is recruiting subjects
United States
 
NCT01550120
055-027
No
Richard Mattes, Purdue University
Purdue University
Not Provided
Principal Investigator: Richard D Mattes, PhD Purdue University
Purdue University
March 2013

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP