Now Available for Public Comment: Notice of Proposed Rulemaking (NPRM) for FDAAA 801 and NIH Draft Reporting Policy for NIH-Funded Trials

Mediators of Inflammation, Prognostic Markers and Genetic Polymorphisms in Patients With Sepsis (MaSep)

This study is currently recruiting participants. (see Contacts and Locations)
Verified February 2012 by Universitätsmedizin Mannheim
Sponsor:
Information provided by (Responsible Party):
Dr. med. Ursula Hoffmann, University Hospital Mannheim
ClinicalTrials.gov Identifier:
NCT01535534
First received: February 14, 2012
Last updated: February 16, 2012
Last verified: February 2012

February 14, 2012
February 16, 2012
January 2012
Not Provided
Not Provided
Not Provided
Complete list of historical versions of study NCT01535534 on ClinicalTrials.gov Archive Site
Not Provided
Not Provided
Not Provided
Not Provided
 
Mediators of Inflammation, Prognostic Markers and Genetic Polymorphisms in Patients With Sepsis
Evaluation of Mediators of Inflammation, Prognostic Markers and Genetic Polymorphisms in Patients With Sepsis

During the past years many investigators have focused on the immunological changes in sepsis disease, and great attention has been paid to the development of practicable means of immunomonitoring. Little is known about diagnostic and prognostic vascular biomarkers during the time course of patients with sepsis.

Primary Outcome Measures:

New diagnostic and prognostic markers for septic patients

Estimated Enrollment: 300 patients Study Start Date: January 2012 Estimated Study Completion Date: open Estimated Primary Completion Date: open

Intervention Details:

Procedure: vein puncture comparison of different inflammatory markers in the blood of septic patients

Observational
Observational Model: Cohort
Time Perspective: Prospective
Not Provided
Retention:   Samples Without DNA
Description:

Peripheral blood samples

Probability Sample

Patients suffering from sepsis

Sepsis
Not Provided
Not Provided
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Recruiting
300
January 2015
Not Provided

Inclusion Criteria:

  • SIRS-Criteria
  • Proven Infection
  • One sepsis-induced organ-failure
  • Adults < 18 years old

Exclusion Criteria:

  • Anemia
  • Pregnancy
  • Blood donor in the last 3 month
Both
18 Years to 90 Years
Yes
Germany
 
NCT01535534
2011-384N-MA
No
Dr. med. Ursula Hoffmann, University Hospital Mannheim
Universitätsmedizin Mannheim
Not Provided
Principal Investigator: Ursula Hoffmann, MD Universitätsmedizin Mannheim
Study Director: Michael Behnes, MD Universitätsmedizin Mannheim
Universitätsmedizin Mannheim
February 2012

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP