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Study of Association Between Maternal Uric Acid , Maternal and Fetal Outcome in Pregnant Women With Hypertension

This study is currently recruiting participants.
Verified January 2012 by Ain Shams Maternity Hospital
Sponsor:
Information provided by (Responsible Party):
nermin marzouk agaibi, Ain Shams Maternity Hospital
ClinicalTrials.gov Identifier:
NCT01523327
First received: January 30, 2012
Last updated: January 31, 2012
Last verified: January 2012
History of Changes

January 30, 2012
January 31, 2012
October 2011
November 2011   (final data collection date for primary outcome measure)
Not Provided
Not Provided
Complete list of historical versions of study NCT01523327 on ClinicalTrials.gov Archive Site
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Not Provided
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Study of Association Between Maternal Uric Acid , Maternal and Fetal Outcome in Pregnant Women With Hypertension
Association of Maternal Uric Acid With Maternal Condition and Fetal Outcome in Pregnant Women With Hypertension

Association of maternal uric acid with maternal condition and fetal outcome in pregnant women with hypertension.

Association of maternal uric acid with maternal condition(renal function,liver function,...ect.) and fetal outcome(birth weight,APGER score) in pregnant women with hypertension.
Observational
Time Perspective: Cross-Sectional
Not Provided
Not Provided
Probability Sample

The study will include 80 pregnant ladies with hypertension admitted to the maternity ward of the hospital who will be divided into two groups according to their uric acid level.
Uric Acid and Hypertension in Pregnancy
Other: measuring protein creatinin ratio,serum uric acid

A non-deproteinized Jaffe reaction is employed to measure creatinine and urinary protein measured by an automated colorimetric assay using pyrogallol red and sodium molybdate.

Measuring of serum uric acid by(2,4,6-tribromo-3-hydroxybenzoic acid)TBHBA by uricase method.
  • A
    40 pregnant Women with hypertension who have uric acid level more than 6 mg per dL.
    Intervention: Other: measuring protein creatinin ratio,serum uric acid
  • B
    40 pregnant women with hypertension who have uric acid level less than 6 mg per dl.
    Intervention: Other: measuring protein creatinin ratio,serum uric acid

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Recruiting
80
October 2012
November 2011   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • Age:18-40 years old
  • Gestational age:28-42 weeks gestation singleton pregnancy of living fetus
  • Non smoker

Exclusion Criteria:

  • women who refuse the study
  • Any medical or obstetric disorders especially D.M.,renal disease,hepatic, cardiac disorders or gout arthritis, other than hypertension if present.
  • Previously elevated uric acid level.
  • Hemolytic or sickle cell anemia,urinary tract infection.
  • Use of diuretics or anti-inflammatory drugs.
Female
18 Years to 40 Years
No
Contact: Nermin marzouk touma, M.B.,B.Ch 01222740182 ext 002 nermindave@gmail.com
Contact: nermin Marzouk touma, M.B.,B.Ch 0862636607 ext 002 nermindave@gmail.com
Egypt
 
NCT01523327
ainshamsMH
Yes
nermin marzouk agaibi, Ain Shams Maternity Hospital
Ain Shams Maternity Hospital
Not Provided
Study Director: Mohamed Saeedeldin Elsafty, assistant lecture Ain Shams Maternity Hospital
Ain Shams Maternity Hospital
January 2012

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP