Incidence and Predictive Factors of Intestinal Injury in Patients Undergoing Heart Valve Replacements

The recruitment status of this study is unknown because the information has not been verified recently.
Verified January 2012 by First Affiliated Hospital, Sun Yat-Sen University.
Recruitment status was  Recruiting
Sponsor:
Information provided by (Responsible Party):
Cai Li, First Affiliated Hospital, Sun Yat-Sen University
ClinicalTrials.gov Identifier:
NCT01516359
First received: January 16, 2012
Last updated: January 19, 2012
Last verified: January 2012

January 16, 2012
January 19, 2012
October 2011
October 2012   (final data collection date for primary outcome measure)
score of gut dysfunction [ Time Frame: eight months ] [ Designated as safety issue: No ]
At different time points, gut dysfunction is graded according to previous criterion.
Same as current
Complete list of historical versions of study NCT01516359 on ClinicalTrials.gov Archive Site
  • The duration of cardiopulmonary bypass [ Time Frame: Eight months ] [ Designated as safety issue: No ]
    Record the duration of cardiopulmonary bypass
  • The duration for aortic artery clamping [ Time Frame: eight months ] [ Designated as safety issue: No ]
Same as current
Not Provided
Not Provided
 
Incidence and Predictive Factors of Intestinal Injury in Patients Undergoing Heart Valve Replacements
Official Title is Required by the WHO and ICMJE

The purpose of this study is to investigate the incidence and predictive factors related to intestinal injury in patients undergoing heart valve replacement through a multicenter study in China.

Intestinal injury is one of main reasons for mobidity and mortality after heart valve replacement, but its incidence and potential risk factors remain unclear. A multicenter study in China is undertaken to investigate the incidence and predictive factors related to intestinal injury in patients undergoing heart valve replacement.

Observational
Time Perspective: Prospective
Not Provided
Retention:   Samples With DNA
Description:

Blood samples are retained for the detections of some biomarkers and gene polymorphism.

Probability Sample

Patients undergoing heart valve replacements under cardiopulmonary bypass

Injury of Other and Multiple Parts of Small Intestine
Not Provided
patients with cardiac surgery
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Recruiting
1000
November 2012
October 2012   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • Patients undergoing heart valve replacements under cardiopulmonary bypass

Exclusion Criteria:

  • Patients who die during or after operation
Both
16 Years to 80 Years
No
Contact: Ke Xuan Liu, MD,Ph.D. 86-20-87755766 ext 8273 liukexuan807@yahoo.com.cn
China
 
NCT01516359
intestinal injury
Yes
Cai Li, First Affiliated Hospital, Sun Yat-Sen University
Cai Li
Not Provided
Principal Investigator: Ke Xuan Liu, MD, Ph.D First Affiliated Hospital, Sun Yat-Sen University
First Affiliated Hospital, Sun Yat-Sen University
January 2012

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP