The Effect of Marketing Variable on Effect of Active Drugs

The recruitment status of this study is unknown because the information has not been verified recently.
Verified December 2011 by Hadassah Medical Organization.
Recruitment status was  Not yet recruiting
Sponsor:
Information provided by (Responsible Party):
Hadassah Medical Organization
ClinicalTrials.gov Identifier:
NCT01493908
First received: December 15, 2011
Last updated: NA
Last verified: December 2011
History: No changes posted

December 15, 2011
December 15, 2011
January 2012
December 2012   (final data collection date for primary outcome measure)
pain thresholds [ Time Frame: 1hour ] [ Designated as safety issue: No ]
Participants will rank their pain thresholds individually and subjectively for a series of pulses. Each participant will experience a series of pulses with random intensity. Pulse intensity will range within 30-90% of the participants maximal level.
Same as current
No Changes Posted
Not Provided
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The Effect of Marketing Variable on Effect of Active Drugs
The Effect of Price and Marketing Variable on the Pain Controlling Effect of Active Drugs in a Clinical Trial.

The efficacy of the placebo effect has been proved in many prior studies by comparing the symptoms and measures of patients. Placebo has been proved to help in treating illnesses such as depression, stomach ulcer and chronic headaches.

A Meta analysis checked 47 studies about placebo and showed great significance when a patient is treated with placebo pill, no active substance, just by activating conditioning and expectation mechanism in his body, thus providing to the healing process, and that is it's importance.

In recent years studies established a relationship between marketing variables (such as price, label) to the efficacy of a product. In addition- a unique research run in 2008 showed a significant relationship between the marketing strategies and the efficacy of medication; more specifically, patients in this research experienced less (controlled) pain when treated with placebo medication introduced to them as more expensive than patients treated with placebo medication that was introduced to them as much cheaper. All patients were treated with the exact same medication.

In the investigator's experiment the investigators design a laboratory experiment to determine if marketing factors could invoke the placebo effects described earlier. For the initial laboratory experiment, we decided to examine the difference in price, on the efficacy of an OTC analgesic through the mediation of low- voltage electrical pulses to the patient's wrist.

The investigators study hypothesis is that marketing variables such as price and brand name will affect the therapeutic efficacy of an analgesic, i.e. a medicine will have greater influence when the patient is aware of its price compared to one who is not.

Not Provided
Interventional
Not Provided
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single Blind (Subject)
Primary Purpose: Treatment
Pain
  • Drug: High price
    Acetaminophen label as high price
  • Drug: Low price
    Acetaminophen label as low price
  • Drug: Low price participants aware paying part
    Acetaminophen label as low price; participants aware they are paying part of the full price
  • Drug: No price
    acetaminophen. No price - price issue not introduced to participants.
  • Drug: Free of charge
    Acetaminophen. participants aware the product is free of charge
  • Active Comparator: High price
    Intervention: Drug: High price
  • Active Comparator: Low price
    Intervention: Drug: Low price
  • Active Comparator: Low price participants aware paying part
    Intervention: Drug: Low price participants aware paying part
  • Active Comparator: No price
    Intervention: Drug: No price
  • Active Comparator: Free of charge
    Intervention: Drug: Free of charge
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Not yet recruiting
220
June 2013
December 2012   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • Healthy Volunteer participants will be between the ages of 18 and 65

Exclusion Criteria:

  • Candidates who have had a history of cardiac problems, epilepsy, diabetes, or are pregnant will be excluded.
  • Taking no pain medication at the time of the experiment.
Both
18 Years to 65 Years
Yes
Contact: Amnon - Lahad, MD, MPH +972-2-6758505 ext - amnonl@cc.huji.ac.il
Contact: Hadas - Lemberg, PhD 00 972 2 6777572 ext - lhadas@hadassah.org.il
Israel
 
NCT01493908
1727-HMO-CTIL
No
Hadassah Medical Organization
Hadassah Medical Organization
Not Provided
Principal Investigator: Amnon - Lahad, MD, MPH Hebrew University, Jerusalem Israel
Hadassah Medical Organization
December 2011

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP