Toothbrushing and Ventilator-associated Pneumonia

This study has been completed.
Sponsor:
Information provided by (Responsible Party):
Miriam Cervino, Hospital Universitario de Canarias
ClinicalTrials.gov Identifier:
NCT01477099
First received: November 16, 2011
Last updated: November 18, 2011
Last verified: November 2011

November 16, 2011
November 18, 2011
August 2010
August 2011   (final data collection date for primary outcome measure)
Prevention of ventilator-associated pneumonia [ Time Frame: 60 days ] [ Designated as safety issue: No ]
Same as current
Complete list of historical versions of study NCT01477099 on ClinicalTrials.gov Archive Site
Not Provided
Not Provided
Not Provided
Not Provided
 
Toothbrushing and Ventilator-associated Pneumonia
Efficacy of Toothbrushing for the Prevention of Ventilator-associated Pneumonia

The hypothesis is that adding the toothbrushing to the oral care with clorhexidine 0.12% could be reduce the incidence of ventilator-associated pneumonia due to that oral cavity may be an important reservoir of pathogens that could cause pneumonia.

Not Provided
Interventional
Phase 4
Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Prevention
Ventilator Associated Pneumonia
Device: Toothbrushing with a manual brush
Toothbrushing with a manual brush
  • Experimental: Toothbrushing with a manual brush
    Toothbrushing with a manual brush
    Intervention: Device: Toothbrushing with a manual brush
  • No Intervention: No toothbrushing
    no toothbrushing
Lorente L, Lecuona M, Jiménez A, Palmero S, Pastor E, Lafuente N, Ramos MJ, Mora ML, Sierra A. Ventilator-associated pneumonia with or without toothbrushing: a randomized controlled trial. Eur J Clin Microbiol Infect Dis. 2012 Oct;31(10):2621-9. Epub 2012 Mar 16.

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
436
August 2011
August 2011   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • mechanical ventilation

Exclusion Criteria:

  • edentulous
Both
18 Years and older
No
Contact information is only displayed when the study is recruiting subjects
Spain
 
NCT01477099
BRUSH-2009
Yes
Miriam Cervino, Hospital Universitario de Canarias
Hospital Universitario de Canarias
Not Provided
Principal Investigator: Leonardo Lorente, Medical Hospital Universitario de Canarias
Hospital Universitario de Canarias
November 2011

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP