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Prevalence of Pulmonary Embolism in ICU (PEICU)

This study has been completed.
Sponsor:
Information provided by (Responsible Party):
University Hospital, Grenoble
ClinicalTrials.gov Identifier:
NCT01457963
First received: October 20, 2011
Last updated: October 21, 2011
Last verified: October 2011
History of Changes

October 20, 2011
October 21, 2011
December 2009
April 2011   (final data collection date for primary outcome measure)
Find a pulmonary embolism on the CT scan [ Time Frame: CT scan at the day of inclusion ] [ Designated as safety issue: No ]
TO estimate the prevalence of PE among consecutive ICU patients receiving MV who required thoracic computed tomography (CT) with contrast agent injection, regardless of whether PE was suspected clinically.
Same as current
Complete list of historical versions of study NCT01457963 on ClinicalTrials.gov Archive Site
To find thrombus on compression ultrasound (CUS) of the four limbs [ Time Frame: CUS within 48 hours after the CT scan ] [ Designated as safety issue: No ]
Same as current
Not Provided
Not Provided
 
Prevalence of Pulmonary Embolism in ICU
Pulmonary Embolism in Mechanically Ventilated Patients Requiring Computed Tomography: Prevalence, Risk Factors and Outcome

The primary objective of this study was to estimate the prevalence of PE among consecutive ICU patients receiving MV who required thoracic computed tomography (CT) with contrast agent injection, regardless of whether PE was suspected clinically. The secondary objectives were to assess the association between PE and DVT, to identify risk factors for VTE, and to determine the outcome of VTE.

Background: Pulmonary embolism (PE) produces nonspecific or minimal symptoms in mechanically ventilated (MV) patients, leading to underdiagnosis. We estimated the prevalence of PE and associations with deep vein thrombosis (DVT) among MV patients.

Methods: Consecutive MV patients who required thoracic computed tomography (CT) in a single ICU. Compression ultrasound of the four limbs was performed within 48 hours of inclusion. Curative anticoagulation therapy was given immediately after PE diagnosis.
Observational
Observational Model: Cohort
Time Perspective: Prospective
Not Provided
Not Provided
Non-Probability Sample

Patients in ICU, mecanically ventilated with a CT scab with iodine injection
  • Pulmonary Embolism
  • Deep Venous Thrombosis
Not Provided
pulmonary embolism, deep venous thrombosis
Minet C, Lugosi M, Savoye PY, Menez C, Ruckly S, Bonadona A, Schwebel C, Hamidfar-Roy R, Dumanoir P, Ara-Somohano C, Ferretti GR, Timsit JF. Pulmonary embolism in mechanically ventilated patients requiring computed tomography: Prevalence, risk factors, and outcome. Crit Care Med. 2012 Dec;40(12):3202-8. doi: 10.1097/CCM.0b013e318265e461.

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
176
April 2011
April 2011   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • all patients requiring invasive MV and thoracic contrast-enhanced CT for any reason

Exclusion Criteria:

  • a diagnosis of PE before ICU admission,
  • allergy to contrast agents,
  • and age younger than 18 years.
Both
18 Years and older
No
Contact information is only displayed when the study is recruiting subjects
France
 
NCT01457963
5891
No
University Hospital, Grenoble
University Hospital, Grenoble
Not Provided
Principal Investigator: Jean Francois TIMSIT, PU/PH University Hospital, Grenoble
University Hospital, Grenoble
October 2011

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP