Development of a Prenatal Test for Fetal Aneuploidy Detection

This study is currently recruiting participants.
Verified January 2013 by Ariosa Diagnostics, Inc
Sponsor:
Information provided by (Responsible Party):
Ariosa Diagnostics, Inc
ClinicalTrials.gov Identifier:
NCT01451671
First received: October 10, 2011
Last updated: January 8, 2013
Last verified: January 2013

October 10, 2011
January 8, 2013
November 2010
November 2015   (final data collection date for primary outcome measure)
Identification of aneuploidy [ Time Frame: At enrollment ] [ Designated as safety issue: No ]
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Complete list of historical versions of study NCT01451671 on ClinicalTrials.gov Archive Site
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Development of a Prenatal Test for Fetal Aneuploidy Detection
Prenatal Test for Fetal Aneuploidy Detection

This is an observational study to develop and evaluate a blood based prenatal blood test. Pregnant women confirmed to be carrying a fetus with a chromosomal abnormality will be eligible. Subjects will be asked to provide a blood sample and a limited amount of clinical data that will be recorded on a case report form. All samples and clinical data will be stripped of subject identifiers prior to submission to Tandem.

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Observational
Observational Model: Case-Only
Time Perspective: Prospective
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Non-Probability Sample

Pregnant women carrying a fetus with an abnormal chromosomal condition that has been confirmed by invasive testing.

Fetal Complications
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*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Recruiting
500
November 2015
November 2015   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • Subject has singleton pregnancy
  • Subject is confirmed via invasive testing to be carrying a fetus with a chromosomal abnormality
  • Subject is able to provide informed consent
  • Subject is ≥ 18 years of age

Exclusion Criteria:

  • Subject is pregnant with more than one fetus
  • Subject (mother) has a known aneuploidy
Female
18 Years and older
No
Contact: Desiree Hollemon, MSN, MPH 503-686-8972 hollemon@ariosadx.com
Contact: Thomas Musci, MD 408-229-7500 tmusci@ariosadx.com
United States
 
NCT01451671
TD002
No
Ariosa Diagnostics, Inc
Ariosa Diagnostics, Inc
Not Provided
Study Chair: Thomas Musci, MD Ariosa Diagnostics
Ariosa Diagnostics, Inc
January 2013

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP