Effects of an Innovative Balance Training Programme in Enhancing Postural Control and Reducing Falls in Patients With Parkinson's Disease

The recruitment status of this study is unknown because the information has not been verified recently.
Verified August 2011 by The Hong Kong Polytechnic University.
Recruitment status was  Recruiting
Sponsor:
Information provided by (Responsible Party):
Margaret Kit Yi Mak, The Hong Kong Polytechnic University
ClinicalTrials.gov Identifier:
NCT01427062
First received: August 30, 2011
Last updated: NA
Last verified: August 2011
History: No changes posted

August 30, 2011
August 30, 2011
March 2009
March 2012   (final data collection date for primary outcome measure)
  • reaction time of limits of stability test [ Time Frame: One year ] [ Designated as safety issue: No ]
  • one-leg-stance time [ Time Frame: one year ] [ Designated as safety issue: No ]
  • pull test [ Time Frame: one year ] [ Designated as safety issue: No ]
    it reflects the ability of compensatory postural control in patients with Parkinson's disease
  • fall rate [ Time Frame: previous one year before baseline assessment, each following one month for 3-month of training and 12-month of follow-up ] [ Designated as safety issue: No ]
  • movement velocity of limit of stability test [ Time Frame: one year ] [ Designated as safety issue: No ]
  • end point excursion of limits of stability test [ Time Frame: One year ] [ Designated as safety issue: No ]
Same as current
No Changes Posted
  • Unified Parkinson`s Disease rating scale- motor examination subscale [ Time Frame: one year ] [ Designated as safety issue: No ]
    it reflects motor impairment of patients with Parkinson's disease
  • Gait velocity [ Time Frame: one year ] [ Designated as safety issue: No ]
  • Stride length [ Time Frame: One year ] [ Designated as safety issue: No ]
  • Cadence [ Time Frame: One year ] [ Designated as safety issue: No ]
Same as current
Not Provided
Not Provided
 
Effects of an Innovative Balance Training Programme in Enhancing Postural Control and Reducing Falls in Patients With Parkinson's Disease
Not Provided

Falling is a complex and most disabling feature for patients with Parkinson's disease (PD). Previous studies suggested that falls in patients with PD are related to postural instability characterized by deficits in anticipatory postural adjustment (APA) for postural orientation in walking and standing and inadequate postural response to perturbation. The present study developed an innovative balance treatment with focus of anticipatory and compensatory postural control and examined its effects on enhancing balance and gait performance and decreasing fall rate in people with PD.

Participants: Forty-two eligible subjects with PD were randomly allocated into balance with focus of anticipatory and compensatory postural control (EXP) or control (CON) group with strength-focused training, with 26 subjects in each group.

Methods: Subjects in the EXP group were trained the speed and amplitude of anticipatory postural adjustment during stepping and walking and postural response to perturbation during walking. Subjects In the CON group were trained to improve the strength of lower limb muscles. Treatment period in both groups lasted for 12 weeks, which consisted of 4-week laboratory-based training (phase 1), 4-week home-based exercise (phase 2) and final 4-week laboratory-based training (phase 3). Outcome measures included reaction time(RT), movement velocity (MV) and endpoint excursion (EPE) of limit-of-stability test, one-leg-stance (OLS) time, gait velocity, stride length (SL), cadence, and fall rate. All tests were conducted for 6 time intervals including baseline, after each training phase, at 3-month follow-up and at 12-month follow-up.

Interventional
Not Provided
Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Single Blind (Outcomes Assessor)
Primary Purpose: Treatment
Parkinson's Disease
  • Other: experimental
    Subjects in the experimental group were trained the speed and amplitude of anticipatory postural adjustment during fall-prone activities and postural response to perturbation during walking. Training was provided with preparatory cues, computerized machines and treadmill.
  • Other: control
    Subjects in control group were provided with strength training of leg muscles using machines and during functional activities.
  • Experimental: anticipatory and compensatory postural control training
    Subjects in the experimental group were trained the speed and amplitude of anticipatory postural adjustment during fall-prone activities and postural response to perturbation during walking. Training was provided with preparatory cues, computerized machines and treadmill.
    Intervention: Other: experimental
  • Active Comparator: strength-focused training
    Subjects in control group were provided with strength training of leg muscles using machines and during functional activities.
    Intervention: Other: control
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Recruiting
52
June 2012
March 2012   (final data collection date for primary outcome measure)

Inclusion Criteria:

  1. diagnosed as parkinson's disease
  2. 45 years old or above
  3. stable on anti-parkinsonian medications for at least 6 weeks prior to entry into the study, which will remain unchanged for the duration of the study
  4. able to walk a 10 meter distance at least 3 times with or without walking aids independently
  5. at stage 2 or 3 of the Hoehn and Yahr staging
  6. able to provide informed consent

Exclusion Criteria:

  1. neurological conditions other than PD
  2. uncompensated cardiovascular disease
  3. less than 23 score on the Mini-Mental State examination,
  4. History of fracture or recent musculoskeletal disorders in back or lower limbs which would interfere with the balance during exercise and daily activities
  5. visual disturbance or vestibular dysfunction limiting locomotion or balance
  6. participation in other balance-related training program more than one time per week
Both
45 Years and older
No
Contact: Xia SHEN, PHD candidate +85262378126 08901970r@polyu.edu.hk
China
 
NCT01427062
PD-001
Not Provided
Margaret Kit Yi Mak, The Hong Kong Polytechnic University
The Hong Kong Polytechnic University
Not Provided
Principal Investigator: Xia SHEN, PHD candidate Department of Rehabilitation Sciences, The Hong Kong Polytechnic University
The Hong Kong Polytechnic University
August 2011

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP